Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_J23
(752 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O67124|RAD50_AQUAE Probable DNA double-strand break repa... 52 1e-06
sp|Q9X1X1|RAD50_THEMA Probable DNA double-strand break repa... 47 6e-05
sp|P22793|TRHY_SHEEP Trichohyalin 46 9e-05
sp|Q61879|MYH10_MOUSE Myosin-10 (Myosin heavy chain, nonmus... 45 3e-04
sp|Q91VW5|GOGA4_MOUSE Golgin subfamily A member 4 (tGolgin-1) 45 3e-04
sp|P35580|MYH10_HUMAN Myosin-10 (Myosin heavy chain, nonmus... 44 4e-04
sp|Q27991|MYH10_BOVIN Myosin-10 (Myosin heavy chain, nonmus... 44 4e-04
sp|P10587|MYH11_CHICK Myosin-11 (Myosin heavy chain, gizzar... 44 4e-04
sp|Q9JLT0|MYH10_RAT Myosin-10 (Myosin heavy chain, nonmuscl... 44 5e-04
sp|P33174|KIF4A_MOUSE Chromosome-associated kinesin KIF4A (... 44 6e-04
>sp|O67124|RAD50_AQUAE Probable DNA double-strand break repair rad50 ATPase
Length = 978
Score = 52.4 bits (124), Expect = 1e-06
Identities = 45/196 (22%), Positives = 93/196 (47%), Gaps = 26/196 (13%)
Frame = +2
Query: 17 ILADKDSQSMQDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQ 196
+ A K + ++ + + ++E+ +E+ ++L++ EELR + +K + NK +K L+
Sbjct: 529 LYAQKINSLKEEMEKLRNEVEELRKEIPENLKERIKKLEELRIEKEKLEHKLNKYRKALE 588
Query: 197 LITAMKDEMCA-------EMELLKRNVPAEDFQKLARELKDLRR--RHQEYRNIILQSDN 349
K+E A E+ELLK + + +L +E K+L R R ++Y + + N
Sbjct: 589 DRQKQKEEAQAKLHKAQTELELLKEKI--REKSRLVKEFKELYRVERLEDYEESLKEEIN 646
Query: 350 RAAINT-----------------DVPSHESRYEQSLEQLKKRLEVLDEKQQQQLPEVLQL 478
IN+ ++ S +S+ E L L + + L+E+++++L E+ +
Sbjct: 647 --YINSKLQEIEEKEKKLRKHFEELSSRKSKLEGELSALNESINSLEEERKEKLKELANI 704
Query: 479 NDYEKGDYEKPEAFFG 526
+ K E E + G
Sbjct: 705 YEVAKSpreVVELYLG 720
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/158 (22%), Positives = 74/158 (46%)
Frame = +2
Query: 20 LADKDSQSMQDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQL 199
+ +K+ + + R ++E EL+ E L+EE + K K+ N + K ++
Sbjct: 655 IEEKEKKLRKHFEELSSRKSKLEGELSALNESINSLEEERKEKLKELANIYEVAKSpreV 714
Query: 200 ITAMKDEMCAEMELLKRNVPAEDFQKLARELKDLRRRHQEYRNIILQSDNRAAINTDVPS 379
+ + AE+E K E FQ L + ++ + +EY I SD + +
Sbjct: 715 VELYLGDKEAELE-RKIKEFEESFQSLKLKKSEIEEKLKEYEGIRELSDIKGEYESVKTQ 773
Query: 380 HESRYEQSLEQLKKRLEVLDEKQQQQLPEVLQLNDYEK 493
E ++++ L ++K+ LE L E+ +++ ++++ EK
Sbjct: 774 LEEKHKK-LGEVKRELEHLGERLKRKEELQKEISELEK 810
Score = 37.4 bits (85), Expect = 0.044
Identities = 34/163 (20%), Positives = 81/163 (49%), Gaps = 12/163 (7%)
Frame = +2
Query: 56 TRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMK-----DE 220
T + R ++ +ELA ++ QEEL R + + +++++ +L +K E
Sbjct: 291 TELKVRKNKLTKELAVLKDELSFAQEELNRIEAEKEKFKEEKEREKELEHRLKKLQEIKE 350
Query: 221 MCAEMELLKRNVPAE--DFQKLARELKDLRRRHQEYRNIILQSDNRAAINTDVPSHE--- 385
+ E+ L ++ + ++++ +E +DL R ++ + ++ +++ + ++ S E
Sbjct: 351 ILKELSQLSSSLKEKEREYEQAKQEFEDLSERVEKGKKLVAETEEKLEKIKELFSEEEYT 410
Query: 386 --SRYEQSLEQLKKRLEVLDEKQQQQLPEVLQLNDYEKGDYEK 508
E+ L +L+++L+ L EK + QL + Q +K +EK
Sbjct: 411 SLKMKERLLVELQRKLKELKEK-EGQLENLTQKYKEKKKVHEK 452
>sp|Q9X1X1|RAD50_THEMA Probable DNA double-strand break repair rad50 ATPase
Length = 852
Score = 47.0 bits (110), Expect = 6e-05
Identities = 35/148 (23%), Positives = 81/148 (54%), Gaps = 5/148 (3%)
Frame = +2
Query: 35 SQSMQDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMK 214
S+ ++ + ++ +++ EE+L + LEK R E +++K + + + Q ++I K
Sbjct: 218 SEKKKELLKKREELQKEEEQLKRLLEKYR---ELVKKKERLRVLSLRRNELQKEVIYEQK 274
Query: 215 DEMCAEMELLKRNV--PAEDFQKLARELKDLRRRHQEYRNIILQSDNRAAINTDVPSHE- 385
+ E+E L R + +F++ ++EL +R++E L+S+ + AI+ ++P H
Sbjct: 275 VKKAKELEPLFREIYLRQREFERFSQELNSREKRYKE-----LESE-KEAISKEIPVHRE 328
Query: 386 --SRYEQSLEQLKKRLEVLDEKQQQQLP 463
S+ E+ E++K+ L++L++ + P
Sbjct: 329 RLSKLEEIGEKIKEELDLLEKVLKASRP 356
>sp|P22793|TRHY_SHEEP Trichohyalin
Length = 1549
Score = 46.2 bits (108), Expect = 9e-05
Identities = 32/156 (20%), Positives = 74/156 (47%)
Frame = +2
Query: 47 QDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEMC 226
+++ + Q+R K +E + LEK L +EE ++ ++ ++K+ L+ + ++E
Sbjct: 545 EEQLQRQEREKRRQEREKQYLEKVELQEEEQLQRQERQKRRQEREKQYLEKVELQEEEQL 604
Query: 227 AEMELLKRNVPAEDFQKLARELKDLRRRHQEYRNIILQSDNRAAINTDVPSHESRYEQSL 406
E KR E EL++ + ++ R Q R + ++ E R ++
Sbjct: 605 QRQEREKRRQERERQYLEKVELQEEEQVQRQEREKRRQERERQYLEKELQRQEERLQEEE 664
Query: 407 EQLKKRLEVLDEKQQQQLPEVLQLNDYEKGDYEKPE 514
+ L++ E +++++Q E ++L + E+ E+ E
Sbjct: 665 QLLREEREKRRQERERQYLEKVELQEEEQLQREERE 700
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/172 (21%), Positives = 83/172 (48%), Gaps = 10/172 (5%)
Frame = +2
Query: 29 KDSQSMQDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITA 208
++ + +Q + R ++R +E E++ LEK L +EE ++ ++ ++K+ L+ +
Sbjct: 430 REEEQLQREEREKRRRQEREKQY---LEKVELWEEEQLQREEREKRRQEREKQYLEKVEL 486
Query: 209 MKDEMCAEMELLKR----------NVPAEDFQKLARELKDLRRRHQEYRNIILQSDNRAA 358
++E E KR V ++ ++L RE ++ RR+ +E R + + + +
Sbjct: 487 REEEQLQRQEREKRRQERERQYLEKVELQEEEQLQREEREKRRQERE-RQYLEKVELQEE 545
Query: 359 INTDVPSHESRYEQSLEQLKKRLEVLDEKQQQQLPEVLQLNDYEKGDYEKPE 514
E R ++ +Q +++E+ +E+Q Q+ + + EK EK E
Sbjct: 546 EQLQRQEREKRRQEREKQYLEKVELQEEEQLQRQERQKRRQEREKQYLEKVE 597
Score = 39.3 bits (90), Expect = 0.011
Identities = 34/169 (20%), Positives = 78/169 (46%), Gaps = 13/169 (7%)
Frame = +2
Query: 47 QDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEMC 226
+++ + ++R K +E + LEK L +EE ++ ++ ++++ L+ + ++E
Sbjct: 461 EEQLQREEREKRRQEREKQYLEKVELREEEQLQRQEREKRRQERERQYLEKVELQEEEQL 520
Query: 227 AEMELLKR----------NVPAEDFQKLARELKDLRRRHQE---YRNIILQSDNRAAINT 367
E KR V ++ ++L R+ ++ RR+ +E + LQ + +
Sbjct: 521 QREEREKRRQERERQYLEKVELQEEEQLQRQEREKRRQEREKQYLEKVELQEEEQLQRQE 580
Query: 368 DVPSHESRYEQSLEQLKKRLEVLDEKQQQQLPEVLQLNDYEKGDYEKPE 514
+ R +Q LE ++E+ +E+Q Q+ + + E+ EK E
Sbjct: 581 RQKRRQEREKQYLE----KVELQEEEQLQRQEREKRRQERERQYLEKVE 625
Score = 39.3 bits (90), Expect = 0.011
Identities = 31/164 (18%), Positives = 76/164 (46%), Gaps = 10/164 (6%)
Frame = +2
Query: 47 QDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEMC 226
+++ + Q+R K +E + LEK L +EE ++ ++ ++++ L+ + ++E
Sbjct: 489 EEQLQRQEREKRRQERERQYLEKVELQEEEQLQREEREKRRQERERQYLEKVELQEEEQL 548
Query: 227 AEMELLKR----------NVPAEDFQKLARELKDLRRRHQEYRNIILQSDNRAAINTDVP 376
E KR V ++ ++L R+ + RR+ +E + + + + +
Sbjct: 549 QRQEREKRRQEREKQYLEKVELQEEEQLQRQERQKRRQERE-KQYLEKVELQEEEQLQRQ 607
Query: 377 SHESRYEQSLEQLKKRLEVLDEKQQQQLPEVLQLNDYEKGDYEK 508
E R ++ Q +++E+ +E+Q Q+ + + E+ EK
Sbjct: 608 EREKRRQERERQYLEKVELQEEEQVQRQEREKRRQERERQYLEK 651
Score = 37.7 bits (86), Expect = 0.033
Identities = 38/154 (24%), Positives = 71/154 (46%)
Frame = +2
Query: 47 QDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEMC 226
+D+ R++ + +++EE K E L +EE R+ + +++ +L ++E
Sbjct: 115 EDQRRFEPQDRQLEERRLKRQELEELAEEEELRE--------KQVRREQRLQRREQEEYG 166
Query: 227 AEMELLKRNVPAEDFQKLARELKDLRRRHQEYRNIILQSDNRAAINTDVPSHESRYEQSL 406
E EL +R E + L RE + R+ +E + + ++ R E R Q
Sbjct: 167 GEEELQQRPKGRELEELLNREQRFERQEQRERQRLQVEQQQR-------QRGELRERQEE 219
Query: 407 EQLKKRLEVLDEKQQQQLPEVLQLNDYEKGDYEK 508
QL+KR E Q+++L E QL ++G E+
Sbjct: 220 VQLQKR--ETQELQRERLEEEQQLQKQKRGLEER 251
Score = 37.4 bits (85), Expect = 0.044
Identities = 32/143 (22%), Positives = 67/143 (46%), Gaps = 5/143 (3%)
Frame = +2
Query: 44 MQDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEM 223
++++ Q R +E+E ++ + R QEE +R+ ++ F ++++ LQ ++E
Sbjct: 1353 LREREEQQLRRQELEGVFSQEEQLRRAEQEEEQRRQRQRDRKFLEEEQSLQ---REREEE 1409
Query: 224 CAEMELLKRNVPAEDFQKLARELKDLRRRH---QEYR--NIILQSDNRAAINTDVPSHES 388
++ R ++ Q E ++LRRR Q+YR + + R ++ E
Sbjct: 1410 KRRVQEQDRKFLEQEEQLHREEQEELRRRQQLDQQYRAEEQFAREEKRRRQEQELRQEEQ 1469
Query: 389 RYEQSLEQLKKRLEVLDEKQQQQ 457
R Q E+ + E L +QQ++
Sbjct: 1470 RRRQERERKFREEEQLRRQQQEE 1492
Score = 32.7 bits (73), Expect = 1.1
Identities = 30/136 (22%), Positives = 69/136 (50%), Gaps = 5/136 (3%)
Frame = +2
Query: 65 QQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEMCAEMELL 244
++R K +E + LEK L +EE ++ ++ ++++ L+ K+E+ + E L
Sbjct: 669 EEREKRRQERERQYLEKVELQEEEQLQREEREKRRQERERQYLE-----KEELQRQEERL 723
Query: 245 KRNVPAEDFQKLARELKDLRRRHQEYRNI---ILQSDNRAAINTDVPSHESRYEQSLE-- 409
+R + ++L RE ++ RR+ +E + + + Q ++R + + Q LE
Sbjct: 724 QR-----EKEQLQREDREKRRQVRERKYLEEELQQEEDRLQREKQLLREDREKRQYLEKV 778
Query: 410 QLKKRLEVLDEKQQQQ 457
+L++ E L ++++Q
Sbjct: 779 ELQREEEQLQREKRRQ 794
Score = 29.6 bits (65), Expect = 9.1
Identities = 41/161 (25%), Positives = 74/161 (45%), Gaps = 6/161 (3%)
Frame = +2
Query: 20 LADKDSQSMQDKTRYQQRIKEIEEELAKSLEKTRLLQE---ELRRK--NKKHGNYFNKQK 184
L +++ Q Q++ R K EE+L + E+ LQE +LR+K K H Q+
Sbjct: 1080 LLEREQQLRQERNR-----KFREEQLLREREEQLRLQEGEPQLRQKRDRKFHEEEQLLQE 1134
Query: 185 KQLQLITAMKD-EMCAEMELLKRNVPAEDFQKLARELKDLRRRHQEYRNIILQSDNRAAI 361
++ QL +D + E ++LK E ++L R+ +D + R +E + R
Sbjct: 1135 REEQLRRQERDRKFREEAQILK-----EREEQLRRQERDRKFREEEQLLQEREELRRQER 1189
Query: 362 NTDVPSHESRYEQSLEQLKKRLEVLDEKQQQQLPEVLQLND 484
+ R + EQL + E L ++Q++ P++ Q D
Sbjct: 1190 EPQLRQERDRKFREEEQLLQEREKL--RRQEREPQLRQERD 1228
>sp|Q61879|MYH10_MOUSE Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 44.7 bits (104), Expect = 3e-04
Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 4/147 (2%)
Frame = +2
Query: 56 TRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEMCAEM 235
TR ++ ++ +EEL K EK ++ EL +KH ++ + + A + E+ AE
Sbjct: 848 TRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA-ETELFAEA 906
Query: 236 ELLKRNVPAEDFQKLARELKDLRRR--HQEYRNIILQSDNR--AAINTDVPSHESRYEQS 403
E ++ + A+ Q+L L DL R +E RN ILQ++ + A D+ E +
Sbjct: 907 EEMRARLAAKK-QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 404 LEQLKKRLEVLDEKQQQQLPEVLQLND 484
++L+ + K ++ EVL L D
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEVLLLED 992
Score = 32.0 bits (71), Expect = 1.8
Identities = 32/136 (23%), Positives = 66/136 (48%), Gaps = 3/136 (2%)
Frame = +2
Query: 20 LADKDSQSMQDKTRYQQRIKEIEEELAKSLEKTRL-LQEELRRKNKKHGNYFNKQKKQLQ 196
L+ + Q ++K Q++ +E EEE K+LEK L LQ +L KK + ++
Sbjct: 1334 LSSRIRQLEEEKNSLQEQQEE-EEEARKNLEKQVLALQSQLADTKKK----VDDDLGTIE 1388
Query: 197 LITAMKDEMCAEMELLKRNVPAE--DFQKLARELKDLRRRHQEYRNIILQSDNRAAINTD 370
+ K ++ ++E L + + + + KL K R QE ++ + D++ I ++
Sbjct: 1389 SLEEAKKKLLKDVEALSQRLEEKVLAYDKLE---KTKNRLQQELDDLTVDLDHQRQIVSN 1445
Query: 371 VPSHESRYEQSLEQLK 418
+ + +++Q L + K
Sbjct: 1446 LEKKQKKFDQLLAEEK 1461
>sp|Q91VW5|GOGA4_MOUSE Golgin subfamily A member 4 (tGolgin-1)
Length = 2238
Score = 44.7 bits (104), Expect = 3e-04
Identities = 40/160 (25%), Positives = 81/160 (50%), Gaps = 14/160 (8%)
Frame = +2
Query: 47 QDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEMC 226
Q+ Y+ RI E+E L KSL++++ E L + N NK+ +TA+ ++
Sbjct: 580 QEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKE------LTALAEQHR 633
Query: 227 AEMELLKR---NVPAEDFQKLARE----LKDLRRRHQEYRNIILQSDNRAAINTDVPSHE 385
E+E L++ ++ E Q L+++ +++LR ++Q+ ++ +L+ E
Sbjct: 634 TEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLK------------EKE 681
Query: 386 SRYEQSLEQL-KKRLEVLDEKQQQ------QLPEVLQLND 484
S ++ ++ + +K LE LD+KQ + +L E L+ D
Sbjct: 682 SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARD 721
Score = 39.3 bits (90), Expect = 0.011
Identities = 42/185 (22%), Positives = 83/185 (44%), Gaps = 33/185 (17%)
Frame = +2
Query: 20 LADKDSQSMQDKT----RYQQRIKEIE--------------EELAKSLEKTRLLQEELRR 145
+ D +++Q+K +QR+KE+E E+L EK++ Q+E+
Sbjct: 1845 VVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDG 1904
Query: 146 KNK-----KHGNYFNKQKKQLQLITAMKDEMCAEMELLKRNVPAEDFQKLA-------RE 289
+NK + N Q ++Q D + +++E K D QKL+ +E
Sbjct: 1905 ENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLE-SKLTGAERDKQKLSKEVARLQKE 1963
Query: 290 LKDLRRRHQEYRNIILQSDNRAA---INTDVPSHESRYEQSLEQLKKRLEVLDEKQQQQL 460
L+ LRR HQ+ +I+ + + A + + E ++ +L+QL + +++Q+L
Sbjct: 1964 LRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQEL 2023
Query: 461 PEVLQ 475
+Q
Sbjct: 2024 ERTVQ 2028
Score = 31.6 bits (70), Expect = 2.4
Identities = 33/174 (18%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Frame = +2
Query: 14 NILADKDSQSMQDKTRYQQRIKEIEEE-LAKSLEKTRLLQEELRRK-NKKHG-NYFNKQK 184
++L + S + + Y++++ +++++ L EK+ L ++ + + +KKH + Q+
Sbjct: 821 DLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQR 880
Query: 185 KQLQLITAMKDEMCAEMELLKRNVPAEDFQKLARELKDLRRRHQEYRNIILQSDNRAAIN 364
Q+Q + + E+ ++ L + + + E + R+ E NIILQ A
Sbjct: 881 AQVQQLERQRSELEEKVRSLAQ-LQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKE 939
Query: 365 TDVPSH------------ESRYEQSLEQLKKRLEVLDEKQQQQLPEVLQLNDYE 490
++ YE + +KR+E + +K ++ +L D E
Sbjct: 940 IEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQE 993
>sp|P35580|MYH10_HUMAN Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 44.3 bits (103), Expect = 4e-04
Identities = 39/147 (26%), Positives = 71/147 (48%), Gaps = 4/147 (2%)
Frame = +2
Query: 56 TRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEMCAEM 235
TR ++ ++ +EEL K EK ++ EL +KH ++ + + A + E+ AE
Sbjct: 848 TRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA-ETELFAEA 906
Query: 236 ELLKRNVPAEDFQKLARELKDLRRR--HQEYRNIILQSDNR--AAINTDVPSHESRYEQS 403
E ++ + A+ Q+L L DL R +E RN ILQ++ + A D+ E +
Sbjct: 907 EEMRARLAAKK-QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 404 LEQLKKRLEVLDEKQQQQLPEVLQLND 484
++L+ + K ++ E+L L D
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLED 992
Score = 31.6 bits (70), Expect = 2.4
Identities = 32/136 (23%), Positives = 65/136 (47%), Gaps = 3/136 (2%)
Frame = +2
Query: 20 LADKDSQSMQDKTRYQQRIKEIEEELAKSLEKTRL-LQEELRRKNKKHGNYFNKQKKQLQ 196
L+ + Q ++K Q++ +E EEE K+LEK L LQ +L KK + ++
Sbjct: 1334 LSSRIRQLEEEKNSLQEQQEE-EEEARKNLEKQVLALQSQLADTKKK----VDDDLGTIE 1388
Query: 197 LITAMKDEMCAEMELLKRNV--PAEDFQKLARELKDLRRRHQEYRNIILQSDNRAAINTD 370
+ K ++ + E L + + A + KL K R QE ++ + D++ + ++
Sbjct: 1389 SLEEAKKKLLKDAEALSQRLEEKALAYDKLE---KTKNRLQQELDDLTVDLDHQRQVASN 1445
Query: 371 VPSHESRYEQSLEQLK 418
+ + +++Q L + K
Sbjct: 1446 LEKKQKKFDQLLAEEK 1461
>sp|Q27991|MYH10_BOVIN Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 44.3 bits (103), Expect = 4e-04
Identities = 39/147 (26%), Positives = 71/147 (48%), Gaps = 4/147 (2%)
Frame = +2
Query: 56 TRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEMCAEM 235
TR ++ ++ +EEL K EK ++ EL +KH ++ + + A + E+ AE
Sbjct: 848 TRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA-ETELFAEA 906
Query: 236 ELLKRNVPAEDFQKLARELKDLRRR--HQEYRNIILQSDNR--AAINTDVPSHESRYEQS 403
E ++ + A+ Q+L L DL R +E RN ILQ++ + A D+ E +
Sbjct: 907 EEMRARLAAKK-QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 404 LEQLKKRLEVLDEKQQQQLPEVLQLND 484
++L+ + K ++ E+L L D
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLED 992
>sp|P10587|MYH11_CHICK Myosin-11 (Myosin heavy chain, gizzard smooth muscle)
Length = 1979
Score = 44.3 bits (103), Expect = 4e-04
Identities = 38/155 (24%), Positives = 70/155 (45%), Gaps = 16/155 (10%)
Frame = +2
Query: 77 KEIEEELAKSLEKTRLLQEELRR-----------KNKKHGN---YFNKQKKQLQLITAMK 214
+E+ EELA + LQ+E RR +++H N ++ +K +Q +
Sbjct: 1717 EEMAEELASANSGRTSLQDEKRRLEARIAQLEEELDEEHSNIETMSDRMRKAVQQAEQLN 1776
Query: 215 DEMCAEMELLKRNVPAEDFQKLARELKDLRRRHQEYRNIILQ--SDNRAAINTDVPSHES 388
+E+ E ++N A Q+L R+ K+LR + QE + AA+ + S E
Sbjct: 1777 NELATERATAQKNENAR--QQLERQNKELRSKLQEMEGAVKSKFKSTIAALEAKIASLEE 1834
Query: 389 RYEQSLEQLKKRLEVLDEKQQQQLPEVLQLNDYEK 493
+ EQ + + + L +K ++ +LQ+ D K
Sbjct: 1835 QLEQEAREKQAAAKTLRQKDKKLKDALLQVEDERK 1869
Score = 38.5 bits (88), Expect = 0.020
Identities = 33/147 (22%), Positives = 73/147 (49%), Gaps = 4/147 (2%)
Frame = +2
Query: 56 TRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEMCAEM 235
TR ++ ++ +EEL ++ E+ + + EL+ +KH ++K LQ + E+ AE
Sbjct: 854 TRQEEEMQAKDEELQRTKERQQKAEAELKELEQKH-TQLCEEKNLLQEKLQAETELYAEA 912
Query: 236 ELLKRNVPA--EDFQKLARELKDLRRRHQEYRNIILQSDNRAAINTDVPSHESRYEQSLE 409
E ++ + A ++ +++ E+ + R +E R+ LQ++ + + E E+
Sbjct: 913 EEMRVRLAAKKQELEEILHEM-EARIEEEEERSQQLQAEKKKMQQQMLDLEEQLEEEEAA 971
Query: 410 QLKKRLE--VLDEKQQQQLPEVLQLND 484
+ K +LE D K ++ ++L + D
Sbjct: 972 RQKLQLEKVTADGKIKKMEDDILIMED 998
Score = 34.7 bits (78), Expect = 0.28
Identities = 36/170 (21%), Positives = 79/170 (46%), Gaps = 17/170 (10%)
Frame = +2
Query: 17 ILADKDSQSMQDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQ 196
I+ D++++ +++ ++R+ ++ LA+ EK + L + KH + ++ + +L+
Sbjct: 995 IMEDQNNKLTKERKLLEERVSDLTTNLAEEEEKAK----NLTKLKNKHESMISELEVRLK 1050
Query: 197 LITAMKDEMCAEMELLKRNVPAE---------DFQKLARELK-DLRRRHQEYRNIIL--- 337
+++ E+E +KR + E + Q ELK L ++ +E + +
Sbjct: 1051 ----KEEKSRQELEKIKRKLEGESSDLHEQIAELQAQIAELKAQLAKKEEELQAALARLE 1106
Query: 338 ----QSDNRAAINTDVPSHESRYEQSLEQLKKRLEVLDEKQQQQLPEVLQ 475
Q +N ++ SH S ++ LE +K EKQ++ L E L+
Sbjct: 1107 DETSQKNNALKKIRELESHISDLQEDLES-EKAARNKAEKQKRDLSEELE 1155
Score = 31.2 bits (69), Expect = 3.1
Identities = 25/106 (23%), Positives = 53/106 (50%), Gaps = 9/106 (8%)
Frame = +2
Query: 29 KDSQSMQDKTRYQQ---RIKEIEEELAKSLEKTRLLQEELRRKNKKHGN------YFNKQ 181
KD + + K R Q+ +KE+E++ + E+ LLQE+L+ + + + +
Sbjct: 863 KDEELQRTKERQQKAEAELKELEQKHTQLCEEKNLLQEKLQAETELYAEAEEMRVRLAAK 922
Query: 182 KKQLQLITAMKDEMCAEMELLKRNVPAEDFQKLARELKDLRRRHQE 319
K++L+ I + E E + + AE +K+ +++ DL + +E
Sbjct: 923 KQELEEILHEMEARIEEEEERSQQLQAEK-KKMQQQMLDLEEQLEE 967
>sp|Q9JLT0|MYH10_RAT Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 43.9 bits (102), Expect = 5e-04
Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 4/147 (2%)
Frame = +2
Query: 56 TRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQLITAMKDEMCAEM 235
TR ++ ++ +EEL K EK ++ EL +KH ++ + + A + E+ AE
Sbjct: 848 TRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA-ETELFAEA 906
Query: 236 ELLKRNVPAEDFQKLARELKDLRRR--HQEYRNIILQSDNR--AAINTDVPSHESRYEQS 403
E ++ + A+ Q+L L DL R +E RN ILQ++ + A D+ E +
Sbjct: 907 EEMRARLAAKK-QELEEILHDLESRVEGEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 404 LEQLKKRLEVLDEKQQQQLPEVLQLND 484
++L+ + K ++ EVL L D
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEVLLLED 992
Score = 31.2 bits (69), Expect = 3.1
Identities = 32/136 (23%), Positives = 66/136 (48%), Gaps = 3/136 (2%)
Frame = +2
Query: 20 LADKDSQSMQDKTRYQQRIKEIEEELAKSLEKTRL-LQEELRRKNKKHGNYFNKQKKQLQ 196
L+ + Q ++K Q++ +E EEE K+LEK L LQ +L KK + ++
Sbjct: 1334 LSSRIRQLEEEKNSLQEQQEE-EEEARKNLEKQVLALQSQLADTKKK----VDDDLGTIE 1388
Query: 197 LITAMKDEMCAEMELLKRNVPAE--DFQKLARELKDLRRRHQEYRNIILQSDNRAAINTD 370
+ K ++ ++E L + + + + KL K R QE ++ + D++ I ++
Sbjct: 1389 GLEEAKKKLLKDVEALSQRLEEKVLAYDKLE---KTKNRLQQELDDLTVDLDHQRQIVSN 1445
Query: 371 VPSHESRYEQSLEQLK 418
+ + +++Q L + K
Sbjct: 1446 LEKKQKKFDQLLAEEK 1461
>sp|P33174|KIF4A_MOUSE Chromosome-associated kinesin KIF4A (Chromokinesin)
Length = 1231
Score = 43.5 bits (101), Expect = 6e-04
Identities = 40/167 (23%), Positives = 79/167 (47%), Gaps = 5/167 (2%)
Frame = +2
Query: 20 LADKDSQSMQDKTRYQQRIKEIEEELAKSLEKTRLLQEELRRKNKKHGNYFNKQKKQLQL 199
+ D+Q + +YQ IK +E E+ LQ E K++ L+L
Sbjct: 544 MTQNDNQLQPIQFQYQDNIKNLESEVLS-------LQRE-------------KEELVLEL 583
Query: 200 ITAMKDEMCAEMELLKRNVPAEDFQKLARELKDLRRRHQEYRNIILQSDNR----AAINT 367
TA KD A++ +R + Q+L ++ DL+++ QE ++ ++ + +N
Sbjct: 584 QTAKKDANQAKLSERRR----KRLQELEGQIADLKKKLQEQSKLLKLKESTEHTVSKLNQ 639
Query: 368 DVPSHESRYEQSLEQLKKRLEVLDEKQQQQLPEVLQLNDYE-KGDYE 505
++ +++ Q + Q+K+ E + +QQ+ EV+QL + + K YE
Sbjct: 640 EIRMMKNQRVQLMRQMKEDAEKFRQWKQQKDKEVIQLKERDRKRQYE 686
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,383,373
Number of Sequences: 369166
Number of extensions: 1187036
Number of successful extensions: 6270
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5394
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6130
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6873311200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)