Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_J04
(786 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-al... 310 2e-84
sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-al... 310 2e-84
sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-al... 310 2e-84
sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alph... 310 2e-84
sp|Q8N752|KC1AL_HUMAN Casein kinase I, alpha-like isoform (... 303 5e-82
sp|P42168|YKL1_CAEEL Putative casein kinase I C03C10.1 in c... 299 7e-81
sp|P54367|KC1A_DROME Casein kinase I, alpha isoform (CKI-al... 290 4e-78
sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delt... 275 1e-73
sp|P48730|KC1D_HUMAN Casein kinase I, delta isoform (CKI-de... 275 1e-73
sp|P49674|KC1E_HUMAN Casein kinase I, epsilon isoform (CKI-... 274 2e-73
>sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67963|KC1A_XENLA Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 337
Score = 310 bits (795), Expect = 2e-84
Identities = 144/195 (73%), Positives = 165/195 (84%)
Frame = +1
Query: 1 VEFIHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTG 180
+E++H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTG
Sbjct: 124 IEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTG 183
Query: 181 TARYASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 360
TARYASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK ST
Sbjct: 184 TARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMST 243
Query: 361 PIEVLCKSFPPEFAFYLEYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQ 540
P+EVLCK FP EFA YL YCR L+F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQ
Sbjct: 244 PVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ 303
Query: 541 KAVGMQQQSHQCGGG 585
KA QQ + G G
Sbjct: 304 KAA--QQAASSSGQG 316
>sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|Q8BK63|KC1A_MOUSE Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 337
Score = 310 bits (795), Expect = 2e-84
Identities = 144/195 (73%), Positives = 165/195 (84%)
Frame = +1
Query: 1 VEFIHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTG 180
+E++H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTG
Sbjct: 124 IEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTG 183
Query: 181 TARYASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 360
TARYASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK ST
Sbjct: 184 TARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMST 243
Query: 361 PIEVLCKSFPPEFAFYLEYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQ 540
P+EVLCK FP EFA YL YCR L+F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQ
Sbjct: 244 PVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ 303
Query: 541 KAVGMQQQSHQCGGG 585
KA QQ + G G
Sbjct: 304 KAA--QQAASSSGQG 316
>sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67828|KC1A_RABIT Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67827|KC1A_BOVIN Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 325
Score = 310 bits (795), Expect = 2e-84
Identities = 144/195 (73%), Positives = 165/195 (84%)
Frame = +1
Query: 1 VEFIHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTG 180
+E++H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTG
Sbjct: 124 IEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTG 183
Query: 181 TARYASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 360
TARYASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK ST
Sbjct: 184 TARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMST 243
Query: 361 PIEVLCKSFPPEFAFYLEYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQ 540
P+EVLCK FP EFA YL YCR L+F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQ
Sbjct: 244 PVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ 303
Query: 541 KAVGMQQQSHQCGGG 585
KA QQ + G G
Sbjct: 304 KAA--QQAASSSGQG 316
>sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 325
Score = 310 bits (795), Expect = 2e-84
Identities = 144/195 (73%), Positives = 165/195 (84%)
Frame = +1
Query: 1 VEFIHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTG 180
+E++H+KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D +T+ HIPYREDKNLTG
Sbjct: 124 IEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTG 183
Query: 181 TARYASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 360
TARYASINAH GIEQSRRDDMES+GYV MYF R++LPWQGLKA KKQKYE+I EKK ST
Sbjct: 184 TARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMST 243
Query: 361 PIEVLCKSFPPEFAFYLEYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQ 540
P+EVLCK FP EFA YL YCR L+F+EAP+Y LR+ F LFRTLN YDY FDWT+LKQ
Sbjct: 244 PVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ 303
Query: 541 KAVGMQQQSHQCGGG 585
KA QQ + G G
Sbjct: 304 KAA--QQAASSSGQG 316
>sp|Q8N752|KC1AL_HUMAN Casein kinase I, alpha-like isoform (CKI-alpha-like) (CK1)
Length = 337
Score = 303 bits (775), Expect = 5e-82
Identities = 139/195 (71%), Positives = 162/195 (83%)
Frame = +1
Query: 1 VEFIHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTG 180
+E++H+KNF+HRDIKPDNFLMG GRHCNKLF++DFGL+KKY+D +T+ HIPYREDK+L G
Sbjct: 124 IEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIG 183
Query: 181 TARYASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 360
T RYASINAH GIEQSRRDDMES+GYVFMYF R++LPWQGLKA KKQKYE+I EKK ST
Sbjct: 184 TVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKKMST 243
Query: 361 PIEVLCKSFPPEFAFYLEYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQ 540
P+EVLCK FP EFA YL YCR L+F+E P+Y LR+ F LFRTLN YDY FDWT+LKQ
Sbjct: 244 PVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ 303
Query: 541 KAVGMQQQSHQCGGG 585
KA QQ + G G
Sbjct: 304 KAA--QQAASSSGQG 316
>sp|P42168|YKL1_CAEEL Putative casein kinase I C03C10.1 in chromosome III
Length = 341
Score = 299 bits (765), Expect = 7e-81
Identities = 141/196 (71%), Positives = 160/196 (81%)
Frame = +1
Query: 1 VEFIHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTG 180
+E++H KNFIHRDIKPDNFLMGIGRHCNKLF++DFGL+KKY+D++T+ HIPYREDKNLTG
Sbjct: 123 IEYVHVKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTG 182
Query: 181 TARYASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 360
TARYASINAH GIEQSRRDDMES+GYV MYF R TLPWQGLKA KKQKYE+I EKK +T
Sbjct: 183 TARYASINAHLGIEQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTT 242
Query: 361 PIEVLCKSFPPEFAFYLEYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQ 540
+E LCK FP EF YL Y R L+FDE+P+Y LR+ F LFRTLN YDY FDWT+LKQ
Sbjct: 243 SVEHLCKGFPAEFPMYLSYTRGLRFDESPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ 302
Query: 541 KAVGMQQQSHQCGGGG 588
KA QQS G G
Sbjct: 303 KA----QQSQSSGVPG 314
>sp|P54367|KC1A_DROME Casein kinase I, alpha isoform (CKI-alpha) (DmCK1)
Length = 337
Score = 290 bits (741), Expect = 4e-78
Identities = 133/181 (73%), Positives = 154/181 (85%)
Frame = +1
Query: 1 VEFIHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTG 180
+E+IH K FIHRDIKPDNFLMGIGRHCNKLF++DFGL+KK++D T+ HI YREDKNLTG
Sbjct: 127 LEYIHLKCFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTG 186
Query: 181 TARYASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 360
TARYASINAH GIEQSRRDDMES+GYV MYF R LPWQG+KAN K+QKYE+I EKK ST
Sbjct: 187 TARYASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMST 246
Query: 361 PIEVLCKSFPPEFAFYLEYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLKQ 540
PIEVLCK P EF+ YL YCR+L+F+E P+Y LR+ F LFRTLN YDY++DWT+LKQ
Sbjct: 247 PIEVLCKGSPAEFSMYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQ 306
Query: 541 K 543
K
Sbjct: 307 K 307
>sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delta)
sp|Q9DC28|KC1D_MOUSE Casein kinase I, delta isoform (CKI-delta) (CKId)
Length = 415
Score = 275 bits (703), Expect = 1e-73
Identities = 123/179 (68%), Positives = 149/179 (83%)
Frame = +1
Query: 1 VEFIHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTG 180
+E+IHSKNFIHRD+KPDNFLMG+G+ N ++++DFGL+KKY+D +T HIPYRE+KNLTG
Sbjct: 116 IEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTG 175
Query: 181 TARYASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 360
TARYASIN H GIEQSRRDD+ES+GYV MYF +LPWQGLKA K+QKYERI EKK ST
Sbjct: 176 TARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMST 235
Query: 361 PIEVLCKSFPPEFAFYLEYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLK 537
PIEVLCK +P EFA YL +CR+L+FD+ P+Y LR+ F NLF F+YDYVFDW +LK
Sbjct: 236 PIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 294
>sp|P48730|KC1D_HUMAN Casein kinase I, delta isoform (CKI-delta) (CKId)
Length = 415
Score = 275 bits (703), Expect = 1e-73
Identities = 123/179 (68%), Positives = 149/179 (83%)
Frame = +1
Query: 1 VEFIHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTG 180
+E+IHSKNFIHRD+KPDNFLMG+G+ N ++++DFGL+KKY+D +T HIPYRE+KNLTG
Sbjct: 116 IEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTG 175
Query: 181 TARYASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 360
TARYASIN H GIEQSRRDD+ES+GYV MYF +LPWQGLKA K+QKYERI EKK ST
Sbjct: 176 TARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMST 235
Query: 361 PIEVLCKSFPPEFAFYLEYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLK 537
PIEVLCK +P EFA YL +CR+L+FD+ P+Y LR+ F NLF F+YDYVFDW +LK
Sbjct: 236 PIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 294
>sp|P49674|KC1E_HUMAN Casein kinase I, epsilon isoform (CKI-epsilon) (CKIe)
Length = 416
Score = 274 bits (700), Expect = 2e-73
Identities = 122/179 (68%), Positives = 149/179 (83%)
Frame = +1
Query: 1 VEFIHSKNFIHRDIKPDNFLMGIGRHCNKLFVVDFGLSKKYKDTKTKAHIPYREDKNLTG 180
+E+IHSKNFIHRD+KPDNFLMG+G+ N ++++DFGL+KKY+D +T HIPYRE+KNLTG
Sbjct: 116 IEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTG 175
Query: 181 TARYASINAHAGIEQSRRDDMESMGYVFMYFLRSTLPWQGLKANNKKQKYERIYEKKRST 360
TARYASIN H GIEQSRRDD+ES+GYV MYF +LPWQGLKA K+QKYERI EKK ST
Sbjct: 176 TARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMST 235
Query: 361 PIEVLCKSFPPEFAFYLEYCRNLKFDEAPNYKSLRESFSNLFRTLNFAYDYVFDWTLLK 537
PIEVLCK +P EF+ YL +CR+L+FD+ P+Y LR+ F NLF F+YDYVFDW +LK
Sbjct: 236 PIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK 294
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,858,926
Number of Sequences: 369166
Number of extensions: 1840850
Number of successful extensions: 7020
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6620
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6908
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7405750800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)