Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_I17
(812 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O75175|CNOT3_HUMAN CCR4-NOT transcription complex subuni... 53 9e-07
sp|Q8K0V4|CNOT3_MOUSE CCR4-NOT transcription complex subuni... 53 9e-07
sp|Q94547|RGA_DROME Regulator of gene activity (Regena prot... 53 1e-06
sp|Q9NZN8|CNOT2_HUMAN CCR4-NOT transcription complex subuni... 52 1e-06
sp|Q8C5L3|CNOT2_MOUSE CCR4-NOT transcription complex subuni... 52 1e-06
sp|P06100|NOT2_YEAST General negative regulator of transcri... 48 4e-05
sp|P04936|POLG_HRV2 Genome polyprotein [Contains: Coat prot... 35 0.19
sp|Q12514|NOT5_YEAST General negative regulator of transcri... 35 0.24
sp|O43918|AIRE_HUMAN Autoimmune regulator (Autoimmune polye... 33 0.71
sp|P36304|POLR_KYMVJ RNA replicase polyprotein 32 2.1
>sp|O75175|CNOT3_HUMAN CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3)
Length = 753
Score = 53.1 bits (126), Expect = 9e-07
Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 3 FWIFYNLTGEECQTTAAKQLMARQWRYNKRDKFWLTRDSKGVNEPTVHPNLERGSYIVWD 182
F+IFY L G + Q AAK L + WR++ + W R + T+ E+G+YI +D
Sbjct: 672 FFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEE---PKTITDEFEQGTYIYFD 728
Query: 183 YEK-AQRVTKILTVYYKDLEN 242
YEK QR + T Y+ LE+
Sbjct: 729 YEKWGQRKKEGFTFEYRYLED 749
>sp|Q8K0V4|CNOT3_MOUSE CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3)
Length = 751
Score = 53.1 bits (126), Expect = 9e-07
Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 3 FWIFYNLTGEECQTTAAKQLMARQWRYNKRDKFWLTRDSKGVNEPTVHPNLERGSYIVWD 182
F+IFY L G + Q AAK L + WR++ + W R + T+ E+G+YI +D
Sbjct: 670 FFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEE---PKTITDEFEQGTYIYFD 726
Query: 183 YEK-AQRVTKILTVYYKDLEN 242
YEK QR + T Y+ LE+
Sbjct: 727 YEKWGQRKKEGFTFEYRYLED 747
>sp|Q94547|RGA_DROME Regulator of gene activity (Regena protein)
Length = 585
Score = 52.8 bits (125), Expect = 1e-06
Identities = 23/73 (31%), Positives = 45/73 (61%)
Frame = +3
Query: 3 FWIFYNLTGEECQTTAAKQLMARQWRYNKRDKFWLTRDSKGVNEPTVHPNLERGSYIVWD 182
F++FY G+ Q AA +L +R+WRY+ +K W+TR G+++ + ERG++ +D
Sbjct: 494 FFLFYTNIGDMMQLMAAAELHSREWRYHVEEKIWITR-IPGIDQYEKNGTKERGTFYYFD 552
Query: 183 YEKAQRVTKILTV 221
+ +R++K+ +
Sbjct: 553 AQSWKRLSKVFQI 565
>sp|Q9NZN8|CNOT2_HUMAN CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)
Length = 540
Score = 52.4 bits (124), Expect = 1e-06
Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 FWIFYNLTGEECQTTAAKQLMARQWRYNKRDKFWLTRDSKGVNEPTVHPN-LERGSYIVW 179
F+++Y G+ Q AA +L R WRY+K ++ W+TR + G+ EPT+ N ERG+Y +
Sbjct: 445 FYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITR-APGM-EPTMKTNTYERGTYYFF 502
Query: 180 DYEKAQRVTKILTVYYKDLE 239
D ++V K + Y LE
Sbjct: 503 DCLNWRKVAKEFHLEYDKLE 522
>sp|Q8C5L3|CNOT2_MOUSE CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)
Length = 540
Score = 52.4 bits (124), Expect = 1e-06
Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 FWIFYNLTGEECQTTAAKQLMARQWRYNKRDKFWLTRDSKGVNEPTVHPN-LERGSYIVW 179
F+++Y G+ Q AA +L R WRY+K ++ W+TR + G+ EPT+ N ERG+Y +
Sbjct: 445 FYLYYMNGGDVLQLLAAVELFNRDWRYHKEERVWITR-APGM-EPTMKTNTYERGTYYFF 502
Query: 180 DYEKAQRVTKILTVYYKDLE 239
D ++V K + Y LE
Sbjct: 503 DCLNWRKVAKEFHLEYDKLE 522
>sp|P06100|NOT2_YEAST General negative regulator of transcription subunit 2
Length = 191
Score = 47.8 bits (112), Expect = 4e-05
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Frame = +3
Query: 3 FWIFYNLTGEECQTTAAKQLMARQWRYNKRDKFWLTRDSKGVNEPTVHPN--LERGSYIV 176
F++FY G Q +L R WRY+K K WLT+D + EP V + ERGSY+
Sbjct: 113 FFLFYKHPGTVIQELTYLELRKRNWRYHKTLKAWLTKDP--MMEPIVSADGLSERGSYVF 170
Query: 177 WDYEKAQRVTKILTVYY 227
+D ++ ++ + ++Y
Sbjct: 171 FDPQRWEKCQRDFLLFY 187
>sp|P04936|POLG_HRV2 Genome polyprotein [Contains: Coat protein VP4 (P1A); Coat protein
VP2 (P1B); Coat protein VP3 (P1C); Coat protein VP1
(P1D); Picornain 2A (Core protein P2A); Core protein
P2B; Core protein P2C; Core protein P3A; Genome-linked
protein VPg (P3B); Picornain 3C (Protease 3C) (P3C);
RNA-directed RNA polymerase (P3D)]
Length = 2150
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 1/93 (1%)
Frame = +3
Query: 84 NKRDKFWLTRDSKGVNEPTVHPNLERGSYIVWDYEKAQRVTKILT-VYYKDLENVTPATT 260
N K L G+ EPT + G++++WD ++ ++ + N +P +
Sbjct: 454 NTTVKLLLAYTPPGIAEPTTRKDAMLGTHVIWDVGLQSTISMVVPWISASHYRNTSPGRS 513
Query: 261 KSLFPFCYNSPFIKRSAVNSSAIPPPQLPPTGR 359
S + C+ + + PPQ PPT R
Sbjct: 514 TSGYITCW---------YQTRLVIPPQTPPTAR 537
>sp|Q12514|NOT5_YEAST General negative regulator of transcription subunit 5
Length = 560
Score = 35.0 bits (79), Expect = 0.24
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Frame = +3
Query: 3 FWIFYNLTGEECQTTAAKQLMA-RQWRYNKRDKFWLTRDSKGVNEPTVHPNLERGSYIVW 179
F+IFY+ G Q AA++L R W +NK D+ W ++ + + P E S+ +
Sbjct: 478 FFIFYHYQGSYEQFLAARELFKNRNWLFNKVDRCWYYKEIEKL--PPGMGKSEEESWRYF 535
Query: 180 DYEKA 194
DY+K+
Sbjct: 536 DYKKS 540
>sp|O43918|AIRE_HUMAN Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis
ectodermal dystrophy protein) (APECED protein)
Length = 545
Score = 33.5 bits (75), Expect = 0.71
Identities = 28/113 (24%), Positives = 53/113 (46%)
Frame = +3
Query: 177 WDYEKAQRVTKILTVYYKDLENVTPATTKSLFPFCYNSPFIKRSAVNSSAIPPPQLPPTG 356
++ E+ R+ IL + KD++ P + K AV + +PPP+LP
Sbjct: 85 YNLERYGRLQPILDSFPKDVDLSQPRKGR------------KPPAVPKALVPPPRLPTKR 132
Query: 357 RTNQKNLATFLQNPSAAASVEARLLNNPISQNFSQPDQMMTSTASQIRVQINN 515
+ +++ A +A A++ R +P SQ ++P + S+A Q R+ + N
Sbjct: 133 KASEEARA------AAPAALTPRGTASPGSQLKAKPPKKPESSAEQQRLPLGN 179
>sp|P36304|POLR_KYMVJ RNA replicase polyprotein
Length = 1874
Score = 32.0 bits (71), Expect = 2.1
Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 6/75 (8%)
Frame = +3
Query: 285 NSPFIKRSAVNSSAIPPPQLPPTGRTNQKNLATFLQNPSAAASVEARLLNNP------IS 446
+SPF+ +N SA+PPPQ PT T + L P V++ L+ +P +S
Sbjct: 722 HSPFLSDGQLNYSALPPPQ-DPTNTT-----LSLLPEPKPPTEVQSPLMADPTCVGPAVS 775
Query: 447 QNFSQPDQMMTSTAS 491
+ P +TAS
Sbjct: 776 FSSLYPRDFFPNTAS 790
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,986,017
Number of Sequences: 369166
Number of extensions: 1567364
Number of successful extensions: 4483
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4296
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4475
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)