Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_I12
(805 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9WUM3|COR1B_MOUSE Coronin-1B (Coronin-2) 140 5e-33
sp|Q9BR76|CO1B_HUMAN Coronin-1B (Coronin-2) 139 1e-32
sp|Q9ULV4|COR1C_HUMAN Coronin-1C (Coronin-3) (hCRNN4) 137 3e-32
sp|O89046|COR1B_RAT Coronin-1B (Coronin-2) 137 4e-32
sp|Q9XS70|COR1B_RABIT Coronin-1B (Coroninse) (Coronin-like ... 136 6e-32
sp|Q920M5|CORO6_MOUSE Coronin-6 (Clipin E) 135 1e-31
sp|Q9WUM4|COR1C_MOUSE Coronin-1C (Coronin-3) 135 1e-31
sp|Q920J3|CORO6_RAT Coronin-6 132 1e-30
sp|Q21624|CORO_CAEEL Coronin-like protein cor-1 129 7e-30
sp|Q92176|COR1A_BOVIN Coronin-1A (Coronin-like protein p57)... 122 1e-27
>sp|Q9WUM3|COR1B_MOUSE Coronin-1B (Coronin-2)
Length = 484
Score = 140 bits (352), Expect = 5e-33
Identities = 79/261 (30%), Positives = 138/261 (52%), Gaps = 2/261 (0%)
Frame = +1
Query: 28 AVNAKYLAVLINCSTVDV-MIRPLEEVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIG 204
AVN K+LAV++ S M+ PL + GR++ + I+WCP +D+++ G
Sbjct: 42 AVNPKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASG 101
Query: 205 QQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGA 384
++ + + +IP+ G+T + ++ + + I+ WHPT N +L++
Sbjct: 102 SEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIT--WHPTARNVLLSA-------- 151
Query: 385 GSSADTHLILWDTVKTEKLLEI-KLNNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSE 561
D +++W+ E+L + L+ + ++S+N+NGS RIID R
Sbjct: 152 --GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGT 209
Query: 562 PVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDLSNPIELIDLDANSG 741
V + H+ AR ++L +G +F+TG+S + R+ ALWD +L P+ L +LD+++G
Sbjct: 210 LVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNG 269
Query: 742 VLYPIYDADINVIYVWGKGDS 804
L P YD D +V+YV GKGDS
Sbjct: 270 ALLPFYDPDTSVVYVCGKGDS 290
>sp|Q9BR76|CO1B_HUMAN Coronin-1B (Coronin-2)
Length = 489
Score = 139 bits (349), Expect = 1e-32
Identities = 78/261 (29%), Positives = 138/261 (52%), Gaps = 2/261 (0%)
Frame = +1
Query: 28 AVNAKYLAVLINCSTVDV-MIRPLEEVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIG 204
AVN K+LAV++ S ++ PL + GR++ + I+WCP +D+++ G
Sbjct: 42 AVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASG 101
Query: 205 QQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGA 384
++ + + +IP+ G+T + ++ + + I+ WHPT N +L++
Sbjct: 102 SEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGII--AWHPTARNVLLSA-------- 151
Query: 385 GSSADTHLILWDTVKTEKLLEI-KLNNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSE 561
D +++W+ E+L + L+ + ++S+N+NGS RIID R
Sbjct: 152 --GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGT 209
Query: 562 PVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDLSNPIELIDLDANSG 741
V + H+ AR ++L +G +F+TG+S + R+ ALWD +L P+ L +LD+++G
Sbjct: 210 LVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNG 269
Query: 742 VLYPIYDADINVIYVWGKGDS 804
L P YD D +V+YV GKGDS
Sbjct: 270 ALLPFYDPDTSVVYVCGKGDS 290
>sp|Q9ULV4|COR1C_HUMAN Coronin-1C (Coronin-3) (hCRNN4)
Length = 474
Score = 137 bits (345), Expect = 3e-32
Identities = 74/261 (28%), Positives = 139/261 (53%), Gaps = 2/261 (0%)
Frame = +1
Query: 28 AVNAKYLAVLINCSTVDV-MIRPLEEVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIG 204
AVN +++A++I S ++ PL + GR++ + I+WCP +D ++ G
Sbjct: 40 AVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASG 99
Query: 205 QQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGA 384
++ + + +IP+ G+T ++ + + S + WHPT N +L++
Sbjct: 100 SEDCTVMVWQIPENGLT--LSLTEPVVILEGHSKRVGIVAWHPTARNVLLSA-------- 149
Query: 385 GSSADTHLILWDTVKTEKLLEIK-LNNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSE 561
D +I+W+ E L+ + +++ + ++S+N NGS + R+ID R E
Sbjct: 150 --GCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRKQE 207
Query: 562 PVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDLSNPIELIDLDANSG 741
V ++ H+ AR ++L +G +F+TG+S + R+ ALW+ ++ PI L ++D ++G
Sbjct: 208 IVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNG 267
Query: 742 VLYPIYDADINVIYVWGKGDS 804
VL P YD D ++IY+ GKGDS
Sbjct: 268 VLLPFYDPDTSIIYLCGKGDS 288
>sp|O89046|COR1B_RAT Coronin-1B (Coronin-2)
Length = 484
Score = 137 bits (344), Expect = 4e-32
Identities = 80/263 (30%), Positives = 139/263 (52%), Gaps = 4/263 (1%)
Frame = +1
Query: 28 AVNAKYLAVLINCSTVDV-MIRPLEEVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIG 204
AVN K+LAV++ S M+ PL + GR++ + I+WCP +D+++ G
Sbjct: 42 AVNPKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASG 101
Query: 205 QQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGA 384
++ + + +IP+ G+T + ++ + + I+ WHPT N +L++
Sbjct: 102 SEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIT--WHPTARNVLLSA-------- 151
Query: 385 GSSADTHLILWDTVKTEKLLEI-KLNNCYLTSLSFNYNGSK--VVCTDNSHITRIIDLRS 555
D +++W+ E+L + L+ + ++S+N+NGS C D S RIID R
Sbjct: 152 --GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCTACKDKS--VRIIDPRR 207
Query: 556 SEPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDLSNPIELIDLDAN 735
V + H+ AR ++L +G +F+ G+S + R+ ALWD + P+ L +LD++
Sbjct: 208 GTLVAEREKAHEGARPMRAIFLADGKVFTAGFSRMSERQLALWDPENFEEPMALQELDSS 267
Query: 736 SGVLYPIYDADINVIYVWGKGDS 804
+G L P YD D +V+YV GKGDS
Sbjct: 268 NGALLPFYDPDTSVVYVCGKGDS 290
>sp|Q9XS70|COR1B_RABIT Coronin-1B (Coroninse) (Coronin-like protein pp66)
Length = 486
Score = 136 bits (343), Expect = 6e-32
Identities = 79/261 (30%), Positives = 136/261 (52%), Gaps = 2/261 (0%)
Frame = +1
Query: 28 AVNAKYLAVLINCSTVDV-MIRPLEEVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIG 204
AVN K+LAV++ S ++ PL + GR++ + IEWCP +D ++ G
Sbjct: 42 AVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIEWCPHNDGVIASG 101
Query: 205 QQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGA 384
++ + + +IP+ G+T + ++ + + I+ WHPT N +L++
Sbjct: 102 SEDCTVMVWQIPEDGLTSPLTEPVVVLEGHTKRVGIVT--WHPTARNVLLSA-------- 151
Query: 385 GSSADTHLILWDTVKTEKLLEI-KLNNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSE 561
D +++W+ E+L + L+ + ++S+N NGS RIID R
Sbjct: 152 --GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNRNGSLFCSACKDKSVRIIDPRRGT 209
Query: 562 PVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDLSNPIELIDLDANSG 741
V + H+ AR ++L +G +F+TG+S + R+ ALWD +L P+ L +LD+++G
Sbjct: 210 LVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNG 269
Query: 742 VLYPIYDADINVIYVWGKGDS 804
L P YD D +V+YV GKGDS
Sbjct: 270 ALLPFYDPDTSVVYVCGKGDS 290
>sp|Q920M5|CORO6_MOUSE Coronin-6 (Clipin E)
Length = 471
Score = 135 bits (341), Expect = 1e-31
Identities = 83/261 (31%), Positives = 134/261 (51%), Gaps = 2/261 (0%)
Frame = +1
Query: 28 AVNAKYLAVLINCSTVDVMI-RPLEEVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIG 204
AVN K+LA+++ I PL + GRV+ + + I+WCP +D+++
Sbjct: 41 AVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASA 100
Query: 205 QQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGA 384
+ + + +IPD T V N + I S + WHPT N +L++ G
Sbjct: 101 SDDTTVMVWQIPD--YTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGG------ 152
Query: 385 GSSADTHLILWDTVKTEKLLEIK-LNNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSE 561
D +I+W+ E LL + ++ + S+ +N NGS + T RIID R S+
Sbjct: 153 ----DNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQ 208
Query: 562 PVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDLSNPIELIDLDANSG 741
V + A H+ AR V+ +G + STG+S + R+ ALWD N+ P+ L ++D ++G
Sbjct: 209 VVAERARPHEGARPLRAVFTADGKLLSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNG 268
Query: 742 VLYPIYDADINVIYVWGKGDS 804
VL P YD D +++Y+ GKGDS
Sbjct: 269 VLLPFYDPDSSIVYLCGKGDS 289
>sp|Q9WUM4|COR1C_MOUSE Coronin-1C (Coronin-3)
Length = 474
Score = 135 bits (340), Expect = 1e-31
Identities = 73/261 (27%), Positives = 139/261 (53%), Gaps = 2/261 (0%)
Frame = +1
Query: 28 AVNAKYLAVLINCSTVDV-MIRPLEEVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIG 204
AVN +++A++I S ++ PL + GR++ + I+WCP +D ++ G
Sbjct: 40 AVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASG 99
Query: 205 QQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGA 384
++ + + +IP+ G+T ++ + + S + WHPT N +L++
Sbjct: 100 SEDCTVMVWQIPENGLT--LSLTEPVVILEGHSKRVGIVAWHPTARNVLLSA-------- 149
Query: 385 GSSADTHLILWDTVKTEKLLEIK-LNNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSE 561
D +I+W+ E L+ + +++ + ++S++ NGS + R+ID R E
Sbjct: 150 --GCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQE 207
Query: 562 PVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDLSNPIELIDLDANSG 741
V ++ H+ AR ++L +G +F+TG+S + R+ ALW+ ++ PI L ++D ++G
Sbjct: 208 IVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNG 267
Query: 742 VLYPIYDADINVIYVWGKGDS 804
VL P YD D ++IY+ GKGDS
Sbjct: 268 VLLPFYDPDTSIIYLCGKGDS 288
>sp|Q920J3|CORO6_RAT Coronin-6
Length = 472
Score = 132 bits (332), Expect = 1e-30
Identities = 82/261 (31%), Positives = 132/261 (50%), Gaps = 2/261 (0%)
Frame = +1
Query: 28 AVNAKYLAVLINCSTVDVMI-RPLEEVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIG 204
AVN K+LA+++ I PL + GRV+ + I I+WCP +D+++
Sbjct: 41 AVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLITGHTGPVLDIDWCPHNDNVIASP 100
Query: 205 QQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGA 384
+ + + +IPD T V N + I S + WHPT N +L++ G
Sbjct: 101 SDDTTVMVWQIPD--YTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGG------ 152
Query: 385 GSSADTHLILWDTVKTEKLLEIK-LNNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSE 561
D +I+W+ E LL + ++ + S+ +N NGS + T RIID R S+
Sbjct: 153 ----DNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQ 208
Query: 562 PVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDLSNPIELIDLDANSG 741
V + H+ R V+ + G IF+TG++ + RE LWD N+ P+ L ++D ++G
Sbjct: 209 VVAERFAAHEGMRPMRAVFTRLGHIFTTGFTRMSQRELGLWDPNNFEEPVALQEMDTSNG 268
Query: 742 VLYPIYDADINVIYVWGKGDS 804
VL P YD D +++Y+ GKGDS
Sbjct: 269 VLLPFYDPDSSIVYLCGKGDS 289
>sp|Q21624|CORO_CAEEL Coronin-like protein cor-1
Length = 605
Score = 129 bits (325), Expect = 7e-30
Identities = 77/257 (29%), Positives = 133/257 (51%)
Frame = +1
Query: 31 VNAKYLAVLINCSTVDVMIRPLEEVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIGQQ 210
VN K++A + + M+ P+ ++GRV+ D + A + + W P +D+++ +
Sbjct: 41 VNPKFIAFINRGAGGPFMVIPVNKIGRVDKDYPFVDAHKAPCLEVAWSPFNDNVIASCSE 100
Query: 211 NGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGAGS 390
+ + IPD G+ N + ++ + WHP N +LT+ G
Sbjct: 101 DTTCKVWVIPDRGLNR--NLSEPAVELTGHQKRVNTIAWHPVANNVLLTAGGENV----- 153
Query: 391 SADTHLILWDTVKTEKLLEIKLNNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSEPVL 570
+ +W+ E LLEI + + S++FN++GS+ V T RI+D + E V+
Sbjct: 154 -----MFMWNVGTGEALLEISGHPDQIWSINFNFDGSQFVTTCKDKKIRILDSHTGE-VV 207
Query: 571 QEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDLSNPIELIDLDANSGVLY 750
E M H+ + Q +++K+GLI STG++ + R YAL DLS PI +LD ++GV++
Sbjct: 208 HEGMGHEGVKPQRAIFVKDGLILSTGFTKRSERLYALRAPEDLSTPIVEEELDTSNGVVF 267
Query: 751 PIYDADINVIYVWGKGD 801
P YD D ++Y+ GKGD
Sbjct: 268 PFYDEDSGLVYLVGKGD 284
>sp|Q92176|COR1A_BOVIN Coronin-1A (Coronin-like protein p57) (Coronin-like protein A)
(CLIPINA) (Tryptophan aspartate-containing coat protein)
(TACO)
Length = 461
Score = 122 bits (306), Expect = 1e-27
Identities = 73/262 (27%), Positives = 135/262 (51%), Gaps = 3/262 (1%)
Frame = +1
Query: 28 AVNAKYLAVLINCSTVDV-MIRPLEEVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIG 204
AVN K++A++ S ++ PL + GRV+ + + + I WCP +D+++ G
Sbjct: 41 AVNPKFVALICEASGGGAFLVLPLGKTGRVDKNVPMVCGHTAPVLDIAWCPHNDNVIASG 100
Query: 205 QQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGA 384
++ + + IPDGG+T + ++ + + I+ WHPT N +L++
Sbjct: 101 SEDCSVMVWEIPDGGLTLPLREPVVTLEGHTKRVGIV--AWHPTAQNVLLSA-------- 150
Query: 385 GSSADTHLILWDTVKTEKLLEI--KLNNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSS 558
D +++WD +L + ++ + S+ ++ +G+ + + RII+ R
Sbjct: 151 --GCDNVILVWDVGTGVAVLTLGSDVHPDTIYSVDWSRDGALICTSCRDKRVRIIEPRKG 208
Query: 559 EPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDLSNPIELIDLDANS 738
V ++ H+ R V++ +G I +TG+S + R+ ALWD L P+ L +LD +S
Sbjct: 209 TIVAEKDRPHEGTRPVRAVFVSDGKILTTGFSRMSERQVALWDTKHLEEPLSLQELDTSS 268
Query: 739 GVLYPIYDADINVIYVWGKGDS 804
GVL P +D D N++Y+ GKGDS
Sbjct: 269 GVLLPFFDPDTNIVYLCGKGDS 290
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.316 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,114,269
Number of Sequences: 369166
Number of extensions: 1960599
Number of successful extensions: 5117
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4898
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5069
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7618580670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)