Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_H23
(439 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O43852|CALU_HUMAN Calumenin precursor (Crocalbin) (IEF S... 66 4e-11
sp|O35887|CALU_MOUSE Calumenin precursor (Crocalbin) 66 4e-11
sp|Q05186|RCN1_MOUSE Reticulocalbin-1 precursor 65 5e-11
sp|O93434|RCN1_FUGRU Reticulocalbin-1 precursor 65 5e-11
sp|O35783|CALU_RAT Calumenin precursor (Crocalbin) (CBP-50) 63 3e-10
sp|Q8BH97|RCN3_MOUSE Reticulocalbin-3 precursor 62 5e-10
sp|Q15293|RCN1_HUMAN Reticulocalbin-1 precursor 61 9e-10
sp|Q96D15|RCN3_HUMAN Reticulocalbin-3 precursor (EF-hand ca... 59 3e-09
sp|Q62703|RCN2_RAT Reticulocalbin-2 precursor (Calcium-bind... 59 3e-09
sp|Q8BP92|RCN2_MOUSE Reticulocalbin-2 precursor (Taipoxin-a... 59 3e-09
>sp|O43852|CALU_HUMAN Calumenin precursor (Crocalbin) (IEF SSP 9302)
Length = 315
Score = 65.9 bits (159), Expect = 4e-11
Identities = 35/104 (33%), Positives = 54/104 (51%)
Frame = +1
Query: 1 DTNNDGMVDKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKP 180
D N DG +D EY+ + + E +K + E+ + DK+++GK+D EE + P
Sbjct: 201 DKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILP 260
Query: 181 GYDAPAKDEVDHLFKESDANKDGVITLDEIESHAHLWIGGEPLD 312
A+ E HL ESD NKDG +T +EI L++G + D
Sbjct: 261 SDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATD 304
Score = 37.0 bits (84), Expect = 0.019
Identities = 20/82 (24%), Positives = 44/82 (53%)
Frame = +1
Query: 76 TEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKPGYDAPAKDEVDHLFKESDANKDGVI 255
T EE K++ + K D DK+G + +E +K ++V+ +K D N+DG++
Sbjct: 65 TPEESKERLGKIVSKIDGDKDGFVTVDELKDWIKFAQKRWIYEDVERQWKGHDLNEDGLV 124
Query: 256 TLDEIESHAHLWIGGEPLDEEG 321
+ +E ++ + ++ +P ++G
Sbjct: 125 SWEEYKNATYGYVLDDPDPDDG 146
Score = 37.0 bits (84), Expect = 0.019
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Frame = +1
Query: 1 DTNNDGMVDKNEY--VTHFHDSEDKKHTE----EEIKKKNEESFDKYDKDKNGKIDPEEY 162
D N DG+V EY T+ + +D + +++ ++E F DKD + EE+
Sbjct: 117 DLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEF 176
Query: 163 YAILKP-GYDAPAKDEVDHLFKESDANKDGVITLDE 267
A L P YD V ++ D N DG I L+E
Sbjct: 177 TAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEE 212
>sp|O35887|CALU_MOUSE Calumenin precursor (Crocalbin)
Length = 315
Score = 65.9 bits (159), Expect = 4e-11
Identities = 35/104 (33%), Positives = 54/104 (51%)
Frame = +1
Query: 1 DTNNDGMVDKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKP 180
D N DG +D EY+ + + E +K + E+ + DK+++GK+D EE + P
Sbjct: 201 DKNADGFIDLEEYIGDMYSHDGNADEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILP 260
Query: 181 GYDAPAKDEVDHLFKESDANKDGVITLDEIESHAHLWIGGEPLD 312
A+ E HL ESD NKDG +T +EI L++G + D
Sbjct: 261 SDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATD 304
Score = 38.5 bits (88), Expect = 0.006
Identities = 20/82 (24%), Positives = 44/82 (53%)
Frame = +1
Query: 76 TEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKPGYDAPAKDEVDHLFKESDANKDGVI 255
T EE K++ + K D DK+G + +E +K ++V+ +K D N+DG++
Sbjct: 65 TPEESKERLGKIVSKIDDDKDGFVTVDELKGWIKFAQKRWIHEDVERQWKGHDLNEDGLV 124
Query: 256 TLDEIESHAHLWIGGEPLDEEG 321
+ +E ++ + ++ +P ++G
Sbjct: 125 SWEEYKNATYGYVLDDPDPDDG 146
Score = 37.0 bits (84), Expect = 0.019
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Frame = +1
Query: 1 DTNNDGMVDKNEY--VTHFHDSEDKKHTE----EEIKKKNEESFDKYDKDKNGKIDPEEY 162
D N DG+V EY T+ + +D + +++ ++E F DKD + EE+
Sbjct: 117 DLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEF 176
Query: 163 YAILKP-GYDAPAKDEVDHLFKESDANKDGVITLDE 267
A L P YD V ++ D N DG I L+E
Sbjct: 177 TAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEE 212
>sp|Q05186|RCN1_MOUSE Reticulocalbin-1 precursor
Length = 325
Score = 65.5 bits (158), Expect = 5e-11
Identities = 37/116 (31%), Positives = 65/116 (56%), Gaps = 1/116 (0%)
Frame = +1
Query: 1 DTNNDGMVDKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEY-YAILK 177
D N DG VD++EY+ ED + + + E+ D D +K+GK+D +E + IL
Sbjct: 210 DKNGDGFVDQDEYIADMFSHEDNGPEPDWVLSEREQFNDFRDLNKDGKLDKDEIRHWILP 269
Query: 178 PGYDAPAKDEVDHLFKESDANKDGVITLDEIESHAHLWIGGEPLDEEGEYSHHYDD 345
YD A+ E HL ESD NKD ++T +EI + ++++G + + + + ++D+
Sbjct: 270 QDYD-HAQAEARHLVYESDKNKDEMLTKEEILDNWNMFVGSQATNYGEDLTKNHDE 324
Score = 35.4 bits (80), Expect = 0.054
Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Frame = +1
Query: 49 FHDSEDKKHTEE----EIKKKNEESFDKYDKDKNGKIDPEEYYAILKPGYDAPAKDEVDH 216
F ED K ++ E K++ + D+ D D +G + EE +K D V
Sbjct: 57 FLGKEDSKTFDQLSPDESKERLGKIVDRIDSDGDGLVTTEELKLWIKRVQKRYIYDNVAK 116
Query: 217 LFKESDANKDGVITLDEIESHAHLWIGGEPLDEEGEYSHH 336
++K+ D +KD I+ +E + + + G P + HH
Sbjct: 117 VWKDYDRDKDEKISWEEYKQATYGYYLGNPAEFHDSSDHH 156
Score = 33.9 bits (76), Expect = 0.16
Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Frame = +1
Query: 49 FHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKP-GYDAPAKDEVDHLFK 225
FHDS D HT +++ ++E F D D + EE+ A L P ++ + V +
Sbjct: 149 FHDSSDH-HTFKKMLPRDERRFKASDLDGDLTATREEFTAFLHPEEFEHMKEIVVLETLE 207
Query: 226 ESDANKDGVITLDE--IESHAHLWIGGEP---LDEEGEYSHHYD 342
+ D N DG + DE + +H G EP L E +++ D
Sbjct: 208 DIDKNGDGFVDQDEYIADMFSHEDNGPEPDWVLSEREQFNDFRD 251
>sp|O93434|RCN1_FUGRU Reticulocalbin-1 precursor
Length = 322
Score = 65.5 bits (158), Expect = 5e-11
Identities = 35/115 (30%), Positives = 65/115 (56%)
Frame = +1
Query: 1 DTNNDGMVDKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKP 180
D N+DG VD++EY+ ED+ E +K + E+ D D +K+GK+D +E + P
Sbjct: 207 DKNSDGHVDEDEYIADMFAHEDRGPEPEWVKTEREQFSDFRDLNKDGKMDLDEIRHWIMP 266
Query: 181 GYDAPAKDEVDHLFKESDANKDGVITLDEIESHAHLWIGGEPLDEEGEYSHHYDD 345
A+ E HL ESD +KD ++T +EI + ++++G + + + + ++D+
Sbjct: 267 QDYDHAQAEARHLVYESDKDKDQMLTKEEILDNWNMFVGSQATNYGEDLTRNHDE 321
Score = 39.3 bits (90), Expect = 0.004
Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 5/117 (4%)
Frame = +1
Query: 1 DTNNDGMVDKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKP 180
D + D ++ E+ + H E+ +H ++ + E+ + DK+ +G +D +EY A +
Sbjct: 170 DLDGDSAANREEFTSFLHP-EEFEHMKDIVVL---ETLEDIDKNSDGHVDEDEYIADMFA 225
Query: 181 GYDAP-----AKDEVDHLFKESDANKDGVITLDEIESHAHLWIGGEPLDEEGEYSHH 336
D K E + D NKDG + LDEI WI + D + H
Sbjct: 226 HEDRGPEPEWVKTEREQFSDFRDLNKDGKMDLDEIRH----WIMPQDYDHAQAEARH 278
>sp|O35783|CALU_RAT Calumenin precursor (Crocalbin) (CBP-50)
Length = 315
Score = 62.8 bits (151), Expect = 3e-10
Identities = 33/104 (31%), Positives = 54/104 (51%)
Frame = +1
Query: 1 DTNNDGMVDKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKP 180
D N DG +D EY+ + + + +K + E+ + DK+++GK+D EE + P
Sbjct: 201 DQNADGFIDLEEYIGDMYSHDGNADEPQWVKTEREQFVEFRDKNRDGKMDKEETKDWILP 260
Query: 181 GYDAPAKDEVDHLFKESDANKDGVITLDEIESHAHLWIGGEPLD 312
A+ E HL ESD +KDG +T +EI L++G + D
Sbjct: 261 SDYDHAEAEARHLVYESDQDKDGKLTKEEIVDKYDLFVGSQATD 304
Score = 40.8 bits (94), Expect = 0.001
Identities = 25/82 (30%), Positives = 42/82 (51%)
Frame = +1
Query: 76 TEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKPGYDAPAKDEVDHLFKESDANKDGVI 255
T EE K+K DK D DK+G + E + +K D V++ ++E D N+DG+I
Sbjct: 65 TPEESKEKLGMIVDKIDTDKDGFVTEGELKSRIKHAQKKYIYDNVENQWQEFDMNQDGLI 124
Query: 256 TLDEIESHAHLWIGGEPLDEEG 321
+ DE + + +P ++G
Sbjct: 125 SWDEYRNVTYGTYLDDPDPDDG 146
>sp|Q8BH97|RCN3_MOUSE Reticulocalbin-3 precursor
Length = 328
Score = 62.0 bits (149), Expect = 5e-10
Identities = 33/116 (28%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
Frame = +1
Query: 1 DTNNDGMVDKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEY-YAILK 177
D N DG V EY+ + E + ++ + ++ + D +K+G++D E Y +L
Sbjct: 213 DKNKDGYVQVEEYIADLYSEEPGEEEPAWVQTERQQFREFRDLNKDGRLDGSEVGYWVLP 272
Query: 178 PGYDAPAKDEVDHLFKESDANKDGVITLDEIESHAHLWIGGEPLDEEGEYSHHYDD 345
P D P E +HL ESD +KDG ++ EI S+ ++++G + + + + H+D+
Sbjct: 273 PSQDQPLV-EANHLLHESDTDKDGRLSKAEILSNWNMFVGSQATNYGEDLTRHHDE 327
>sp|Q15293|RCN1_HUMAN Reticulocalbin-1 precursor
Length = 331
Score = 61.2 bits (147), Expect = 9e-10
Identities = 35/116 (30%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Frame = +1
Query: 1 DTNNDGMVDKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEY-YAILK 177
D N DG VD++EY+ E+ + + + E+ + D +K+GK+D +E + IL
Sbjct: 216 DKNGDGFVDQDEYIADMFSHEENGPEPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILP 275
Query: 178 PGYDAPAKDEVDHLFKESDANKDGVITLDEIESHAHLWIGGEPLDEEGEYSHHYDD 345
YD A+ E HL ESD NKD +T +EI + ++++G + + + + ++D+
Sbjct: 276 QDYD-HAQAEARHLVYESDKNKDEKLTKEEILENWNMFVGSQATNYGEDLTKNHDE 330
Score = 37.0 bits (84), Expect = 0.019
Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Frame = +1
Query: 49 FHDSEDKKH----TEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKPGYDAPAKDEVDH 216
F ED K T +E K++ + D+ D D +G + EE +K D V
Sbjct: 63 FLGKEDSKTFDQLTPDESKERLGKIVDRIDNDGDGFVTTEELKTWIKRVQKRYIFDNVAK 122
Query: 217 LFKESDANKDGVITLDEIESHAHLWIGGEPLDEEGEYSHH 336
++K+ D +KD I+ +E + + + G P + HH
Sbjct: 123 VWKDYDRDKDDKISWEEYKQATYGYYLGNPAEFHDSSDHH 162
>sp|Q96D15|RCN3_HUMAN Reticulocalbin-3 precursor (EF-hand calcium-binding protein RLP49)
Length = 328
Score = 59.3 bits (142), Expect = 3e-09
Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 1/116 (0%)
Frame = +1
Query: 1 DTNNDGMVDKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEY-YAILK 177
D N DG V EY+ + +E + ++ + ++ D D +K+G +D E + +L
Sbjct: 213 DRNKDGYVQVEEYIADLYSAEPGEEEPAWVQTERQQFRDFRDLNKDGHLDGSEVGHWVLP 272
Query: 178 PGYDAPAKDEVDHLFKESDANKDGVITLDEIESHAHLWIGGEPLDEEGEYSHHYDD 345
P D P E +HL ESD +KDG ++ EI + ++++G + + + + H+D+
Sbjct: 273 PAQDQPLV-EANHLLHESDTDKDGRLSKAEILGNWNMFVGSQATNYGEDLTRHHDE 327
>sp|Q62703|RCN2_RAT Reticulocalbin-2 precursor (Calcium-binding protein ERC-55)
(Taipoxin-associated calcium-binding protein 49)
(TCBP-49)
Length = 320
Score = 59.3 bits (142), Expect = 3e-09
Identities = 34/119 (28%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
Frame = +1
Query: 1 DTNNDGMVDKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKP 180
D N DG V E++ + E I + + + YDKD +G++DP+E + + P
Sbjct: 202 DKNGDGFVSLEEFLGDYRRDPTANEDPEWILVEKDRFVNDYDKDSDGRLDPQELLSWVVP 261
Query: 181 GYDAPAKDEVDHLFKESDANKDGVITLDEIESHAHLWIGGEPLD--EEGEYSHHYDDEL 351
A++E HL E D N D ++ +EI + L++ E D + + Y DEL
Sbjct: 262 NNQGIAQEEALHLIDEMDLNSDKKLSEEEILENQDLFLTSEATDYGRQLHDDYFYHDEL 320
Score = 39.7 bits (91), Expect = 0.003
Identities = 29/101 (28%), Positives = 49/101 (48%), Gaps = 12/101 (11%)
Frame = +1
Query: 1 DTNNDGMVDKNEY-------VTHFHDSEDKKHTEEE----IKKKNEESFDKYDKDKNGKI 147
D N+DG V +EY V F ++ TEEE + K+++ F+K ++D +
Sbjct: 113 DKNSDGTVTWDEYNVQMYDRVIDFDENTALDDTEEESFRQLHLKDKKRFEKANQDSGPGL 172
Query: 148 DPEEYYAILKP-GYDAPAKDEVDHLFKESDANKDGVITLDE 267
+ EE+ A P D + + +E D N DG ++L+E
Sbjct: 173 NLEEFIAFEHPEEVDYMTEFVIQEALEEHDKNGDGFVSLEE 213
Score = 34.7 bits (78), Expect = 0.092
Identities = 23/81 (28%), Positives = 34/81 (41%)
Frame = +1
Query: 25 DKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKPGYDAPAKD 204
D +EYV H EE +++ + K D D +G + E ++ + A
Sbjct: 53 DVDEYVKLGH---------EEQQRRLQSIIKKIDSDSDGFLTENELSQWIQMSFKHYAMQ 103
Query: 205 EVDHLFKESDANKDGVITLDE 267
E F E D N DG +T DE
Sbjct: 104 EAKQQFVEYDKNSDGTVTWDE 124
>sp|Q8BP92|RCN2_MOUSE Reticulocalbin-2 precursor (Taipoxin-associated calcium-binding
protein 49) (TCBP-49)
Length = 320
Score = 59.3 bits (142), Expect = 3e-09
Identities = 34/119 (28%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
Frame = +1
Query: 1 DTNNDGMVDKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKP 180
D N DG V E++ + E I + + + YDKD +G++DP+E + + P
Sbjct: 202 DKNGDGFVSLEEFLGDYRRDPTANEDPEWILVEKDRFVNDYDKDNDGRLDPQELLSWVVP 261
Query: 181 GYDAPAKDEVDHLFKESDANKDGVITLDEIESHAHLWIGGEPLD--EEGEYSHHYDDEL 351
A++E HL E D N D ++ +EI + L++ E D + + Y DEL
Sbjct: 262 NNQGIAQEEALHLIDEMDLNSDKKLSEEEILENQDLFLTSEATDYGRQLHDDYFYHDEL 320
Score = 38.1 bits (87), Expect = 0.008
Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 12/101 (11%)
Frame = +1
Query: 1 DTNNDGMVDKNEY-------VTHFHDSEDKKHTEE----EIKKKNEESFDKYDKDKNGKI 147
D N+DG V +EY V F ++ TEE ++ K+++ F+K ++D +
Sbjct: 113 DKNSDGAVTWDEYNIQMYDRVIDFDENTALDDTEEGSFRQLHLKDKKRFEKANQDSGPGL 172
Query: 148 DPEEYYAILKP-GYDAPAKDEVDHLFKESDANKDGVITLDE 267
EE+ A P D + + +E D N DG ++L+E
Sbjct: 173 SLEEFIAFEHPEEVDYMTEFVIQEALEEHDKNGDGFVSLEE 213
Score = 34.7 bits (78), Expect = 0.092
Identities = 23/81 (28%), Positives = 34/81 (41%)
Frame = +1
Query: 25 DKNEYVTHFHDSEDKKHTEEEIKKKNEESFDKYDKDKNGKIDPEEYYAILKPGYDAPAKD 204
D +EYV H EE +++ + K D D +G + E ++ + A
Sbjct: 53 DVDEYVKLGH---------EEQQRRLQSIIKKIDSDSDGFLTENELSQWIQMSFKHYAMQ 103
Query: 205 EVDHLFKESDANKDGVITLDE 267
E F E D N DG +T DE
Sbjct: 104 EAKQQFVEYDKNSDGAVTWDE 124
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,637,959
Number of Sequences: 369166
Number of extensions: 720097
Number of successful extensions: 5412
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4549
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5234
length of database: 68,354,980
effective HSP length: 100
effective length of database: 49,881,480
effective search space used: 2244666600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)