Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_G15
(586 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UNH7|SNX6_HUMAN Sorting nexin-6 (TRAF4-associated fact... 158 1e-38
sp|Q5R613|SNX6_PONPY Sorting nexin-6 158 1e-38
sp|Q9Y5X3|SNX5_HUMAN Sorting nexin-5 142 8e-34
sp|Q9D8U8|SNX5_MOUSE Sorting nexin-5 141 1e-33
sp|P25343|RV161_YEAST Reduced viability upon starvation pro... 37 0.036
sp|P30199|EPIP_STAEP Epidermin leader peptide-processing se... 35 0.11
sp|Q8NDV3|SM1L2_HUMAN Structural maintenance of chromosome ... 35 0.11
sp|P50478|AMPH_CHICK Amphiphysin 33 0.40
sp|Q92JK8|CLPB_RICCN Chaperone clpB 32 0.89
sp|P49418|AMPH_HUMAN Amphiphysin 32 1.5
>sp|Q9UNH7|SNX6_HUMAN Sorting nexin-6 (TRAF4-associated factor 2)
Length = 406
Score = 158 bits (399), Expect = 1e-38
Identities = 76/136 (55%), Positives = 108/136 (79%)
Frame = +2
Query: 68 FLALSKVFEEVRKLENRIATDEDLKLSDTLRYYQNDSQAAKALLYRRSRALADYDSASKA 247
FL +S++F++ RK+E R++ DEDLKLSD L+YY +SQAAK LLYRRSR+L DY++A+KA
Sbjct: 267 FLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKA 326
Query: 248 VEKARIKGKEVAAAEGTQSISYDKFKKISESAKTQIMDFKQRRIAYFKKNLTELTKLQLK 427
++KAR K K+V AE +Q + KF+KISESAK +++DFK RR+A F+KNL EL +L+LK
Sbjct: 327 LDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELK 386
Query: 428 HARSHIQVLRTALNAL 475
HA+ ++Q+L+ L L
Sbjct: 387 HAKGNLQLLQNCLAVL 402
>sp|Q5R613|SNX6_PONPY Sorting nexin-6
Length = 406
Score = 158 bits (399), Expect = 1e-38
Identities = 76/136 (55%), Positives = 108/136 (79%)
Frame = +2
Query: 68 FLALSKVFEEVRKLENRIATDEDLKLSDTLRYYQNDSQAAKALLYRRSRALADYDSASKA 247
FL +S++F++ RK+E R++ DEDLKLSD L+YY +SQAAK LLYRRSR+L DY++A+KA
Sbjct: 267 FLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKA 326
Query: 248 VEKARIKGKEVAAAEGTQSISYDKFKKISESAKTQIMDFKQRRIAYFKKNLTELTKLQLK 427
++KAR K K+V AE +Q + KF+KISESAK +++DFK RR+A F+KNL EL +L+LK
Sbjct: 327 LDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELK 386
Query: 428 HARSHIQVLRTALNAL 475
HA+ ++Q+L+ L L
Sbjct: 387 HAKGNLQLLQNCLAVL 402
>sp|Q9Y5X3|SNX5_HUMAN Sorting nexin-5
Length = 404
Score = 142 bits (357), Expect = 8e-34
Identities = 63/136 (46%), Positives = 111/136 (81%)
Frame = +2
Query: 71 LALSKVFEEVRKLENRIATDEDLKLSDTLRYYQNDSQAAKALLYRRSRALADYDSASKAV 250
L ++++FE++RK+E R+++DEDLKL++ LRYY + +AAK LLYRR++AL DY++++KA+
Sbjct: 267 LKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKAL 326
Query: 251 EKARIKGKEVAAAEGTQSISYDKFKKISESAKTQIMDFKQRRIAYFKKNLTELTKLQLKH 430
+KAR+K K+V AE Q KF+++SESAK ++++FK++R+A F+KNL E+++L++KH
Sbjct: 327 DKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKH 386
Query: 431 ARSHIQVLRTALNALK 478
AR+++ +L++ ++ K
Sbjct: 387 ARNNVSLLQSCIDLFK 402
>sp|Q9D8U8|SNX5_MOUSE Sorting nexin-5
Length = 404
Score = 141 bits (355), Expect = 1e-33
Identities = 63/136 (46%), Positives = 111/136 (81%)
Frame = +2
Query: 71 LALSKVFEEVRKLENRIATDEDLKLSDTLRYYQNDSQAAKALLYRRSRALADYDSASKAV 250
L ++++FE++RK+E R+++DEDLKL++ LRYY + +AAK LLYRR++AL DY++++KA+
Sbjct: 267 LKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKAL 326
Query: 251 EKARIKGKEVAAAEGTQSISYDKFKKISESAKTQIMDFKQRRIAYFKKNLTELTKLQLKH 430
+KAR+K K+V AE Q KF+++SESAK ++++FK++R+A F+KNL E+++L++KH
Sbjct: 327 DKARLKSKDVKLAETHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKH 386
Query: 431 ARSHIQVLRTALNALK 478
AR+++ +L++ ++ K
Sbjct: 387 ARNNVSLLQSCIDLFK 402
>sp|P25343|RV161_YEAST Reduced viability upon starvation protein 161
Length = 265
Score = 37.0 bits (84), Expect = 0.036
Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
Frame = +2
Query: 161 YYQNDSQAAKALLYRRSRALADYDSAS----KAVEKARIKGKEVAAAEGTQSISYDKFKK 328
Y++ +A K +R D+D+A + V+K ++ AE S++ D F+
Sbjct: 126 YFKEIEEAIK----KRDHKKQDFDAAKAKVRRLVDKPAKDASKLPRAEKELSLAKDIFEN 181
Query: 329 ISESAKTQIMDFKQRRIAYFKKNLTELTKLQLK 427
++ KT++ R+ YF + L K+QL+
Sbjct: 182 LNNQLKTELPQLVSLRVPYFDPSFEALIKIQLR 214
>sp|P30199|EPIP_STAEP Epidermin leader peptide-processing serine protease epiP precursor
Length = 461
Score = 35.4 bits (80), Expect = 0.11
Identities = 22/59 (37%), Positives = 30/59 (50%)
Frame = +2
Query: 161 YYQNDSQAAKALLYRRSRALADYDSASKAVEKARIKGKEVAAAEGTQSISYDKFKKISE 337
Y D+Q K L R DYD+ KA+ A+ KG V AA G I+ K K+I++
Sbjct: 255 YLIKDNQNKKKL---RDDEKVDYDALQKAINYAQKKGSIVVAAVGNDGINVKKVKEINK 310
>sp|Q8NDV3|SM1L2_HUMAN Structural maintenance of chromosome 1-like 2 protein (SMC1beta
protein)
Length = 1235
Score = 35.4 bits (80), Expect = 0.11
Identities = 32/128 (25%), Positives = 59/128 (46%), Gaps = 11/128 (8%)
Frame = +2
Query: 131 EDLKLSDTLRYYQNDSQAAKALLYRRSRALADYDSASKAVEKARIKGKEVAAAEGTQSIS 310
E +K + +YQ SQ LL S+ + S+ +++ + + KE E +
Sbjct: 720 EMIKKKHLVAFYQEQSQLQSELLNIESQCIM----LSEGIKERQRRIKEFQ--EKIDKVE 773
Query: 311 YDKFKKISESAKTQ-IMDFKQRRIA----------YFKKNLTELTKLQLKHARSHIQVLR 457
D F+ E + I +F+ + + ++KK LT L +QL+++RSH++
Sbjct: 774 DDIFQHFCEEIGVENIREFENKHVKRQQEIDQKRYFYKKMLTRLN-VQLEYSRSHLKKKL 832
Query: 458 TALNALKE 481
+N LKE
Sbjct: 833 NKINTLKE 840
>sp|P50478|AMPH_CHICK Amphiphysin
Length = 682
Score = 33.5 bits (75), Expect = 0.40
Identities = 24/97 (24%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Frame = +2
Query: 152 TLRYYQNDSQAAKALLYRRSRALADYDSASKAVE-----KARIKGKEVAAAEGTQSISYD 316
TL Y K + +RSR L DYDSA +E K + +G+ A E Q +
Sbjct: 120 TLDTYLGQFPDIKTRIAKRSRKLVDYDSARHHLEALQSSKRKDEGRITKAEEEFQK-AQK 178
Query: 317 KFKKISESAKTQIMDFKQRRIAYFKKNLTELTKLQLK 427
F++ + + ++ RR+ ++ ++ L+ K
Sbjct: 179 VFEEFNTDLQEELPSLWSRRVGFYVNTFKNVSSLEAK 215
>sp|Q92JK8|CLPB_RICCN Chaperone clpB
Length = 857
Score = 32.3 bits (72), Expect = 0.89
Identities = 20/54 (37%), Positives = 28/54 (51%)
Frame = +2
Query: 326 KISESAKTQIMDFKQRRIAYFKKNLTELTKLQLKHARSHIQVLRTALNALKEPS 487
KI S+K + +D RRI K L L K +H++ I+ L TAL L+ S
Sbjct: 403 KIELSSKPEELDELDRRIIQIKIELAALKKENDEHSKKKIEHLTTALEKLESQS 456
>sp|P49418|AMPH_HUMAN Amphiphysin
Length = 695
Score = 31.6 bits (70), Expect = 1.5
Identities = 22/96 (22%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Frame = +2
Query: 152 TLRYYQNDSQAAKALLYRRSRALADYDSAS---KAVEKARIKGK-EVAAAEGTQSISYDK 319
TL Y K + +RSR L DYDSA +A++ ++ K + ++ AE +
Sbjct: 120 TLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKV 179
Query: 320 FKKISESAKTQIMDFKQRRIAYFKKNLTELTKLQLK 427
F++ + + ++ RR+ ++ ++ L+ K
Sbjct: 180 FEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAK 215
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,919,101
Number of Sequences: 369166
Number of extensions: 899298
Number of successful extensions: 2855
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2803
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2853
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4357244645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)