Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_G12
(812 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 112 2e-24
sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 111 3e-24
sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 110 4e-24
sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 71 3e-12
sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 70 5e-12
sp|Q22431|ARI2_CAEEL Probable ariadne-2 protein (Ari-2) 59 1e-08
sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-betwe... 58 3e-08
sp|Q924T7|RNF31_MOUSE RING finger protein 31 58 4e-08
sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen rece... 54 5e-07
sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 52 3e-06
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3
(UbcM4-interacting protein 28)
Length = 498
Score = 112 bits (279), Expect = 2e-24
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 6/204 (2%)
Frame = +1
Query: 1 ECLIC---LENKKGISVERCEHVFCKKCLRNHIKNSKGYPVTCPSGYYESQCDEILSDYF 171
EC +C L + + + C H FC++CL+ I+NS+ V CP C L +
Sbjct: 269 ECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVACPFIDSTYSCPGKLLERE 328
Query: 172 CYEILSKNDHASYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCY 351
+LS D+ + ++ + Y C DC G ++ + TC C ++C
Sbjct: 329 IRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCL 388
Query: 352 KCKALHEN---EESCEDWTAKNENSINLRNQQKLLNEERIKNNEAIYCMKCGMFLVYTGG 522
CKA+HE+ E +D + +N + R ++L + ++ EA++C +C + + G
Sbjct: 389 LCKAIHEHMNCREYQDDLALRAQNDVAARQTTEML-KVMLQQGEAMHCPQCRIVVQKKDG 447
Query: 523 CDWICCPYCHHEICFVTKLSQWGP 594
CDWI C CH EIC+VTK +WGP
Sbjct: 448 CDWIRCTVCHTEICWVTKGPRWGP 471
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B
virus X-associated protein 4) (HBV-associated factor 4)
(RING finger protein 54)
Length = 500
Score = 111 bits (277), Expect = 3e-24
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 6/204 (2%)
Frame = +1
Query: 1 ECLIC---LENKKGISVERCEHVFCKKCLRNHIKNSKGYPVTCPSGYYESQCDEILSDYF 171
EC +C L + + + C H FC++CL+ I+NS+ V+CP C L +
Sbjct: 271 ECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLERE 330
Query: 172 CYEILSKNDHASYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCY 351
+L+ D+ + ++ + Y C DC G ++ + TC C ++C
Sbjct: 331 IKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCL 390
Query: 352 KCKALHEN---EESCEDWTAKNENSINLRNQQKLLNEERIKNNEAIYCMKCGMFLVYTGG 522
CKA+HE +E ED + +N + R ++L + ++ EA+ C +C + + G
Sbjct: 391 LCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEML-KVMLQQGEAMRCPQCQIVVQKKDG 449
Query: 523 CDWICCPYCHHEICFVTKLSQWGP 594
CDWI C CH EIC+VTK +WGP
Sbjct: 450 CDWIRCTVCHTEICWVTKGPRWGP 473
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein
interacting with PKC) (Protein kinase C-binding protein
beta-15)
Length = 498
Score = 110 bits (276), Expect = 4e-24
Identities = 61/204 (29%), Positives = 98/204 (48%), Gaps = 6/204 (2%)
Frame = +1
Query: 1 ECLIC---LENKKGISVERCEHVFCKKCLRNHIKNSKGYPVTCPSGYYESQCDEILSDYF 171
EC +C L + + + C H FC++CL+ I+NS+ V+CP C L +
Sbjct: 269 ECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCPGKLLERE 328
Query: 172 CYEILSKNDHASYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAISCY 351
+LS D+ + ++ + Y C DC G ++ + TC C ++C
Sbjct: 329 IRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCL 388
Query: 352 KCKALHEN---EESCEDWTAKNENSINLRNQQKLLNEERIKNNEAIYCMKCGMFLVYTGG 522
CKA+HE E +D + N + + ++L ++ EA+YC +C + + G
Sbjct: 389 LCKAIHERMNCREYQDDLAHRARNDVAAQQTTEMLRV-MLQQGEAMYCPQCRIVVQKKDG 447
Query: 523 CDWICCPYCHHEICFVTKLSQWGP 594
CDWI C CH EIC+VTK +WGP
Sbjct: 448 CDWIRCTVCHTEICWVTKGPRWGP 471
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
Length = 493
Score = 71.2 bits (173), Expect = 3e-12
Identities = 47/207 (22%), Positives = 85/207 (41%), Gaps = 12/207 (5%)
Frame = +1
Query: 4 CLICLE--NKKGISVERCEHVFCKKCLRNH----IKNSKGYPVTCPSGYYESQCDEILSD 165
C +C++ K+ + C+H FC+ C H +K+ G V+C + C +
Sbjct: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMA----QDCPLRTPE 194
Query: 166 YFCYEILSKNDHASYNKRRLAHRCFEQS--DLYPCYNSDCSGTVKLNNNQFQHT-CQRCK 336
F + +L N+ RR R + +S L C +DC +++ + + C RC
Sbjct: 195 DFVFPLLP-NEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCN 253
Query: 337 AISCYKCKALHENEESC---EDWTAKNENSINLRNQQKLLNEERIKNNEAIYCMKCGMFL 507
+ C+KC+ ++ C W K + N ++ C KC + +
Sbjct: 254 EVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKD---------CPKCNICI 304
Query: 508 VYTGGCDWICCPYCHHEICFVTKLSQW 588
GGC+ + C C H+ C++ L W
Sbjct: 305 EKNGGCNHMQCSKCKHDFCWMC-LGDW 330
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
(UbcM4-interacting protein 48)
Length = 492
Score = 70.5 bits (171), Expect = 5e-12
Identities = 46/207 (22%), Positives = 85/207 (41%), Gaps = 12/207 (5%)
Frame = +1
Query: 4 CLICLE--NKKGISVERCEHVFCKKCLRNH----IKNSKGYPVTCPSGYYESQCDEILSD 165
C +C++ K+ + C+H FC+ C H +K+ G ++C + C +
Sbjct: 138 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGISCMA----QDCPLRTPE 193
Query: 166 YFCYEILSKNDHASYNKRRLAHRCFEQS--DLYPCYNSDCSGTVKLNNNQFQHT-CQRCK 336
F + +L N+ RR R + +S L C +DC +++ + + C RC
Sbjct: 194 DFVFPLLP-NEELRDKYRRYLFRDYVESHFQLQLCPGADCPMVIRVQEPRARRVQCNRCS 252
Query: 337 AISCYKCKALHENEESC---EDWTAKNENSINLRNQQKLLNEERIKNNEAIYCMKCGMFL 507
+ C+KC+ ++ C W K + N ++ C KC + +
Sbjct: 253 EVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKD---------CPKCNICI 303
Query: 508 VYTGGCDWICCPYCHHEICFVTKLSQW 588
GGC+ + C C H+ C++ L W
Sbjct: 304 EKNGGCNHMQCSKCKHDFCWMC-LGDW 329
>sp|Q22431|ARI2_CAEEL Probable ariadne-2 protein (Ari-2)
Length = 482
Score = 59.3 bits (142), Expect = 1e-08
Identities = 40/180 (22%), Positives = 67/180 (37%), Gaps = 6/180 (3%)
Frame = +1
Query: 49 CEHVFCKKCLRNHIKNSKGYPVTCPSGYYESQCDEILSDYFCYEILSKND--HASYNKRR 222
C H FC+ C ++H+++ V ES+C+ F I+ + Y +
Sbjct: 145 CGHCFCEHCWKSHVESRLSEGVASRIECMESECEVYAPSEFVLSIIKNSPVIKLKYERFL 204
Query: 223 LAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQH-TCQRCKAISCYKCKALHENEESCE--- 390
L L C ++C ++ + + TC +C C KC A + SCE
Sbjct: 205 LRDMVNSHPHLKFCVGNECPVIIRSTEVKPKRVTCMQCHTSFCVKCGADYHAPTSCETIK 264
Query: 391 DWTAKNENSINLRNQQKLLNEERIKNNEAIYCMKCGMFLVYTGGCDWICCPYCHHEICFV 570
W K + N ++ C +C + GGC+ I C C H C++
Sbjct: 265 QWMTKCADDSETANYISAHTKD---------CPQCHSCIEKAGGCNHIQCTRCRHHFCWM 315
>sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-between-RING-finger
ubiquitin-associated domain protein)
Length = 1072
Score = 58.2 bits (139), Expect = 3e-08
Identities = 52/209 (24%), Positives = 76/209 (36%), Gaps = 21/209 (10%)
Frame = +1
Query: 1 ECLIC---LENKKGISVERCEHVFCKKCLRNH----IKNSKGYPVTCPS-GYYESQCDEI 156
EC +C L + + ++ CE C C R H +K + CP+ G + D
Sbjct: 698 ECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQ 757
Query: 157 LSDYFCY------EILSKNDHASYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQH 318
L YF E L + +A ++K+ C + CS Q +
Sbjct: 758 LLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWC--AQCSFGFIYEREQLEA 815
Query: 319 TCQRCKAISCYKCKALHENE---ESCED---WTAKNENSINLRNQQKLLNEERIKNNEAI 480
TC +C C +CK E + SCED W N+ + L E I
Sbjct: 816 TCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQE------NGI 869
Query: 481 YCMKCGM-FLVYTGGCDWICCPYCHHEIC 564
C KC + + GGC C C H+ C
Sbjct: 870 DCPKCKFSYALARGGCMHFHCTQCRHQFC 898
>sp|Q924T7|RNF31_MOUSE RING finger protein 31
Length = 1066
Score = 57.8 bits (138), Expect = 4e-08
Identities = 52/209 (24%), Positives = 76/209 (36%), Gaps = 21/209 (10%)
Frame = +1
Query: 1 ECLIC---LENKKGISVERCEHVFCKKCLRNH----IKNSKGYPVTCPS-GYYESQCDEI 156
EC +C L + ++ CE C +C R H +K + CP+ G + D
Sbjct: 692 ECAVCGWALPRNRMQALISCECTICPECFRQHFTIALKEKHITDMVCPACGRPDLTDDAQ 751
Query: 157 LSDYFCY------EILSKNDHASYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQH 318
L YF E L + +A ++K+ C + CS Q +
Sbjct: 752 LLSYFSTLDIQLRESLDPDAYALFHKKLTEAVLMRDPKFLWC--AQCSFGFIYEREQLEA 809
Query: 319 TCQRCKAISCYKCKALHENE---ESCED---WTAKNENSINLRNQQKLLNEERIKNNEAI 480
TC +C C +CK E + SCED W N+ + L E I
Sbjct: 810 TCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRTNDPEYQAQGLAMYLQE------NGI 863
Query: 481 YCMKCGM-FLVYTGGCDWICCPYCHHEIC 564
C KC + + GGC C C H+ C
Sbjct: 864 DCPKCKFSYALARGGCMHFHCTQCRHQFC 892
>sp|Q9JI90|RNF14_MOUSE RING finger protein 14 (Androgen receptor-associated protein 54)
(Triad2 protein)
Length = 485
Score = 53.9 bits (128), Expect = 5e-07
Identities = 50/220 (22%), Positives = 79/220 (35%), Gaps = 31/220 (14%)
Frame = +1
Query: 4 CLICLENKKGISVE---RCEHVFCKKCLRNH----IKNSKGYPVTCPSGYYESQCDEILS 162
C IC K G C+HV+CK CL+++ IK+ + + CP E QC + +
Sbjct: 221 CSICFCEKLGSDCMYFLECKHVYCKACLKDYFEIQIKDGQVKCLNCP----EPQCPSVAT 276
Query: 163 DYFCYEILSKNDHASYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAI 342
E++ + A Y++ L +D+ C C V C C
Sbjct: 277 PGQVKELVEADLFARYDRLLLQSTLDLMADVVYCPRPCCQLPVMQEPGGTMAICSSCNFA 336
Query: 343 SCYKCKALHENEESCEDWTAKNENSINLRNQ---------------------QKLLNEER 459
C C+ + C+ E I+LRN+ QK L E
Sbjct: 337 FCTLCRLTYHGLSPCK---VTAEKLIDLRNEYLQADEATKRFLEQRYGKRVIQKALEEME 393
Query: 460 IKN---NEAIYCMKCGMFLVYTGGCDWICCPYCHHEICFV 570
K+ + C CG + GC+ + C C C++
Sbjct: 394 SKDWLEKNSKSCPCCGTPIQKLDGCNKMTCTGCMQYFCWI 433
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region
Length = 551
Score = 51.6 bits (122), Expect = 3e-06
Identities = 46/219 (21%), Positives = 83/219 (37%), Gaps = 16/219 (7%)
Frame = +1
Query: 4 CLICLENKKGISVE-RCEHVFCKKCLRNHIKNS--KGYPVTCPS---GYYESQCDEILSD 165
C+IC + K + C H +C C R++IK+ +G +TC D+++
Sbjct: 179 CIICCDKKDTETFALECGHEYCINCYRHYIKDKLHEGNIITCMDCSLALKNEDIDKVMGH 238
Query: 166 YFCYEILSKNDHASYNKRRLAHRCFEQSDLYPCYNSDCSGTVKLNNNQFQHTCQRCKAIS 345
+++ + + K ++ C +DC V L + R
Sbjct: 239 PSSSKLMDSSIKSFVQKHNRNYKW--------CPFADCKSIVHLRDTSSLPEYTRLHYSP 290
Query: 346 CYKCKALHE----------NEESCEDWTAKNENSINLRNQQKLLNEERIKNNEAIYCMKC 495
KC + H + C+ TA + + R + ++LN E C KC
Sbjct: 291 FVKCNSFHRFCFNCGFEVHSPADCKITTAWVKKA---RKESEILNWVLSHTKE---CPKC 344
Query: 496 GMFLVYTGGCDWICCPYCHHEICFVTKLSQWGPEVTNRF 612
+ + GGC+ + C C +E C++ + W P N F
Sbjct: 345 SVNIEKNGGCNHMVCSSCKYEFCWICE-GPWAPHGKNFF 382
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,296,902
Number of Sequences: 369166
Number of extensions: 1814540
Number of successful extensions: 5224
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4724
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5163
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)