Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_F11
(771 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P81021|VIGLN_CHICK Vigilin 145 2e-34
sp|Q00341|VIGLN_HUMAN Vigilin (High density lipoprotein-bin... 144 3e-34
sp|Q8VDJ3|VIGLN_MOUSE Vigilin (High density lipoprotein-bin... 142 8e-34
sp|Q9Z1A6|VIGLN_RAT Vigilin (High density lipoprotein-bindi... 139 6e-33
sp|P06105|SC160_YEAST Protein SCP160 (Protein HX) 61 3e-09
sp|O34374|YJIB_BACSU Putative cytochrome P450 yjiB 36 0.10
sp|Q12114|CHS5_YEAST Chitin biosynthesis protein CHS5 (Prot... 36 0.13
sp|Q9PWD6|HXA10_MORSA Homeobox protein Hox-A10 35 0.17
sp|P31260|HXA10_HUMAN Homeobox protein Hox-A10 (Hox-1H) (Ho... 33 0.66
sp|Q8CAS9|BAL_MOUSE B aggressive lymphoma protein homolog 33 0.86
>sp|P81021|VIGLN_CHICK Vigilin
Length = 1270
Score = 145 bits (365), Expect = 2e-34
Identities = 92/259 (35%), Positives = 147/259 (56%), Gaps = 7/259 (2%)
Frame = +1
Query: 1 HRNLITRNMTEIKNIQNSFDVMIKFPNRDIS-SKSGENGYDEAHLNGNSDNTFVDTTEEG 177
HR+++ + I+ I + V IKFP+R+ + + E E NG EG
Sbjct: 886 HRSIMGPKGSRIQQITRDYGVQIKFPDREENPAPVAEPALQE---NGEEGG-------EG 935
Query: 178 DSNVEAEQNNP--ANWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQKGQG 351
+A+ ++P + + +SGRRE CE+AKEAL LVPV+ +V + + HR IGQKG G
Sbjct: 936 KDGKDADPSSPRKCDIIIISGRREKCEAAKEALQALVPVTIEVEVPFDLHRYIIGQKGSG 995
Query: 352 INTFSTKYNVVVNIP-PANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNF 528
I ++ V + +P P + D I+I G ANL AKAGL E + + E++DR R+F
Sbjct: 996 IRKMMDEFEVNIQVPAPELQSSDIITITGLAANLDRAKAGLLERVKELQAEQEDRALRSF 1055
Query: 529 ENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKS---EEITIRGYEEDVKKA 699
+ V V +H K+IG++GA I R++ V+IQ PD++ +S ++ITI GYE++ + A
Sbjct: 1056 KLTVTVDPKYHPKIIGRKGAVITQIRTEHEVNIQFPDKDDESQAQDQITITGYEKNAEAA 1115
Query: 700 EDELLSMVDRWKAQVIEEL 756
D ++ +V + V E++
Sbjct: 1116 RDAIMKIVGELEQMVSEDV 1134
Score = 82.8 bits (203), Expect = 9e-16
Identities = 56/197 (28%), Positives = 101/197 (51%), Gaps = 9/197 (4%)
Frame = +1
Query: 202 NNPANWVALSGRRENCESAKEALLELVPVSE-----DVPLNNEFHRNFIGQKGQGINTFS 366
N +N + + G + + AK+ LLEL E D+ + +FHR IGQKG+ I
Sbjct: 474 NEKSNLIRIEGDPQGVQQAKKELLELASRMENERTKDLIIEQKFHRTIIGQKGERIREIR 533
Query: 367 TKY-NVVVNIP-PANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQV 540
K+ V++N P PA+K D + ++GP+ + + +++ D + +F V
Sbjct: 534 EKFPEVIINFPDPAHKS-DIVQLRGPKNEVEKCTKYMQKMVA-------DLVENSFSISV 585
Query: 541 PVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSE-EITIRGYEEDVKKAEDELLS 717
P+ FH+ +IG+ GANI+ R + N I +P + ++ ++ +G E+ VK +L+
Sbjct: 586 PIFKQFHKNIIGKGGANIKKIREESNTKIDLPGREQATQRQLLSQGREQTVKLLRHRILA 645
Query: 718 MVDRWKAQVIE-ELHIP 765
+ + A + E E+ IP
Sbjct: 646 -IQKELANITEVEVSIP 661
Score = 60.5 bits (145), Expect = 5e-09
Identities = 53/215 (24%), Positives = 98/215 (45%), Gaps = 6/215 (2%)
Frame = +1
Query: 136 GNSDNTFVDTTEEGDSNVEAEQNNPANWVALSGRRENCESAKEALLELVPVSEDVPLNNE 315
G N+ + E+ +VE + ++ + R E +AL E+ + +++
Sbjct: 311 GRKGNSLQEILEKTGVSVEIPPTDSSSETVIL--RGEPEKLGQALTEVYAKANSFTVSSV 368
Query: 316 -----FHRNFIGQKGQGINTFSTKY-NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDE 477
HR IG GQ + + + + + D I+ +GP ++ A+ ++
Sbjct: 369 SAPSWLHRFIIGLFGQNLAKITQQMPKIHIEFTEGE---DKITSEGPTEDVNVAQEQIEV 425
Query: 478 LIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSE 657
++ +D I R ++ V FHR LIG+ GANI + + VS++IP N KS
Sbjct: 426 MV-------KDLINRTDYAEINVDHKFHRHLIGKNGANINRIKDLYKVSVRIPPDNEKSN 478
Query: 658 EITIRGYEEDVKKAEDELLSMVDRWKAQVIEELHI 762
I I G + V++A+ ELL + R + + ++L I
Sbjct: 479 LIRIEGDPQGVQQAKKELLELASRMENERTKDLII 513
Score = 54.3 bits (129), Expect = 4e-07
Identities = 41/176 (23%), Positives = 83/176 (47%), Gaps = 6/176 (3%)
Frame = +1
Query: 202 NNPANWVALSGRRENCESAKEALLELVPVSED------VPLNNEFHRNFIGQKGQGINTF 363
++P+N + ++G +E E A+ +L L+ +D + + +H G + ++
Sbjct: 189 DDPSNQIKITGTKEGIEKARHEIL-LISAEQDKRAVERLDVEKVYHPFIAGPYNKLVSEL 247
Query: 364 STKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVP 543
+NIPP + I G + L A A + + ++E +K+ + V
Sbjct: 248 MQDTGTRINIPPPSVNKTEIVFTGEKEQLAQAVARVKK---IYEEKKK----KTTTIAVE 300
Query: 544 VPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDEL 711
V H+ +IG++G +++ K VS++IP +S SE + +RG E + +A E+
Sbjct: 301 VKKSQHKYVIGRKGNSLQEILEKTGVSVEIPPTDSSSETVILRGEPEKLGQALTEV 356
Score = 51.6 bits (122), Expect = 2e-06
Identities = 52/234 (22%), Positives = 99/234 (42%), Gaps = 7/234 (2%)
Frame = +1
Query: 43 IQNSFDVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTTEEGDSNVEAEQNNPANWV 222
++NSF + + + + G+ G + + S NT +D + + +
Sbjct: 577 VENSFSISVPIFKQFHKNIIGKGGANIKKIREES-NTKID--------LPGREQATQRQL 627
Query: 223 ALSGRRENCESAKEALL----ELVPVSE-DVPLNNEFHRNFIGQKGQGINTFSTKYNVV- 384
GR + + + +L EL ++E +V + ++ H + IG KG+ I + + V
Sbjct: 628 LSQGREQTVKLLRHRILAIQKELANITEVEVSIPSKLHNSLIGAKGRFIRSIMEECGGVH 687
Query: 385 VNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHR 564
++ P ++I+ ++ W EKQ +++ + +H+
Sbjct: 688 IHFPTEGSGSATVTIRAQPRTWRKPRSSC----CTWAEEKQ---TKSYTVDLRAKPEYHK 740
Query: 565 KLIGQRGANIEMFRSKFNVSIQIPDQNSKSEE-ITIRGYEEDVKKAEDELLSMV 723
LIG+ G NI R I P K +E ITI G EE VK+A+ EL +++
Sbjct: 741 FLIGKGGGNIRKVRDNTGARIIFPTSEDKDQELITIMGTEEAVKEAQKELEALI 794
Score = 50.4 bits (119), Expect = 5e-06
Identities = 37/163 (22%), Positives = 79/163 (48%), Gaps = 7/163 (4%)
Frame = +1
Query: 220 VALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHRNFIGQKGQGINTFSTKYN-V 381
+ + G E + A++ L L+ V + + ++ + HR+F+ ++GQ + + +Y V
Sbjct: 774 ITIMGTEEAVKEAQKELEALIKNLDNVVEDSMVVDPKHHRHFVIRRGQVLREIADEYGGV 833
Query: 382 VVNIPPANKCL-DFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVF 558
+V +P + D +++KG + + AK + E+I + E Q I + +P F
Sbjct: 834 MVRLPTVSGTQSDKVTLKGAKDCVEAAKKRIQEIIE--DLEAQVTI------ECTIPQKF 885
Query: 559 HRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEED 687
HR ++G +G+ I+ + V I+ PD+ + +E+
Sbjct: 886 HRSIMGPKGSRIQQITRDYGVQIKFPDREENPAPVAEPALQEN 928
Score = 48.1 bits (113), Expect = 3e-05
Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 8/131 (6%)
Frame = +1
Query: 400 ANKCLDFISIKGPRANLIDAK--------AGLDELIVVWENEKQDRIARNFENQVPVPIV 555
A CLD + G L AK +G E ++ E R+ V +P
Sbjct: 100 AKICLDIMQKTGAHLELSLAKDQGLSIMVSGKLEAVMKARKEIVARLQTQASATVAIPKE 159
Query: 556 FHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWK 735
HR +IG+ G ++ K IQIP + S +I I G +E ++KA E+L +
Sbjct: 160 HHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEILLISAEQD 219
Query: 736 AQVIEELHIPR 768
+ +E L + +
Sbjct: 220 KRAVERLDVEK 230
Score = 48.1 bits (113), Expect = 3e-05
Identities = 52/248 (20%), Positives = 105/248 (42%), Gaps = 4/248 (1%)
Frame = +1
Query: 37 KNIQNSFDVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTTEEGDSNVEAE-QNNPA 213
K + N +V + P++ +S G G + + EG + + P
Sbjct: 648 KELANITEVEVSIPSKLHNSLIGAKGRFIRSIMEECGGVHIHFPTEGSGSATVTIRAQPR 707
Query: 214 NWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNI 393
W R C A+E + V D+ E+H+ IG+ G I +
Sbjct: 708 TW--RKPRSSCCTWAEEKQTKSYTV--DLRAKPEYHKFLIGKGGGNIRKVRDNTGARIIF 763
Query: 394 PPA-NKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKL 570
P + +K + I+I G + +A+ L+ LI +N +D + V HR
Sbjct: 764 PTSEDKDQELITIMGTEEAVKEAQKELEALIKNLDNVVEDSMV--------VDPKHHRHF 815
Query: 571 IGQRGANIEMFRSKFN-VSIQIPD-QNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQV 744
+ +RG + ++ V +++P ++S+++T++G ++ V+ A+ + +++ +AQV
Sbjct: 816 VIRRGQVLREIADEYGGVMVRLPTVSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQV 875
Query: 745 IEELHIPR 768
E IP+
Sbjct: 876 TIECTIPQ 883
>sp|Q00341|VIGLN_HUMAN Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 144 bits (362), Expect = 3e-34
Identities = 93/258 (36%), Positives = 144/258 (55%), Gaps = 6/258 (2%)
Frame = +1
Query: 1 HRNLITRNMTEIKNIQNSFDVMIKFPNRDISS-KSGENGYDEAHLNGNSDNTFVDTTEEG 177
HR+++ + I+ I F V IKFP+R+ ++ S E E NG D EG
Sbjct: 885 HRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQE---NG-------DEAGEG 934
Query: 178 DSNVEAEQNNP--ANWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQKGQG 351
+ + +P + + +SGR+E CE+AKEAL LVPV+ +V + + HR IGQKG G
Sbjct: 935 REAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSG 994
Query: 352 INTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFE 531
I ++ V +++P D I+I G ANL AKAGL E + + E++DR R+F+
Sbjct: 995 IRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFK 1054
Query: 532 NQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQ---NSKSEEITIRGYEEDVKKAE 702
V V +H K+IG++GA I R + +V+IQ PD+ N ++ITI GYE++ + A
Sbjct: 1055 LSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAAR 1114
Query: 703 DELLSMVDRWKAQVIEEL 756
D +L +V + V E++
Sbjct: 1115 DAILRIVGELEQMVSEDV 1132
Score = 89.0 bits (219), Expect = 1e-17
Identities = 56/192 (29%), Positives = 95/192 (49%), Gaps = 7/192 (3%)
Frame = +1
Query: 211 ANWVALSGRRENCESAKEALLELVPVSE-----DVPLNNEFHRNFIGQKGQGINTFSTKY 375
+N + + G + + AK LLEL E D+ + FHR IGQKG+ I K+
Sbjct: 478 SNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKF 537
Query: 376 -NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPI 552
V++N P + D + ++GP+ + + +++ D + ++ VP+
Sbjct: 538 PEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVA-------DLVENSYSISVPIFK 590
Query: 553 VFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRW 732
FH+ +IG+ GANI+ R + N I +P +NS SE I I G + + A +LS + +
Sbjct: 591 QFHKNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILS-IQKD 649
Query: 733 KAQVIE-ELHIP 765
A + E E+ IP
Sbjct: 650 LANIAEVEVSIP 661
Score = 80.5 bits (197), Expect = 5e-15
Identities = 70/238 (29%), Positives = 111/238 (46%), Gaps = 5/238 (2%)
Frame = +1
Query: 25 MTEIKNIQNSFDVMI----KFPNRDISSKSGENGYDEAHLNGNSDNTFVDTTEEGDSNVE 192
+TE+ NSF V + +R I K G+N A + ++ TE G+ +
Sbjct: 354 LTEVYAKANSFTVSSVAAPSWLHRFIIGKKGQN---LAKITQQMPKVHIEFTE-GEDKIT 409
Query: 193 AEQNNPANWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQKGQGINTFSTK 372
E P V ++ +E E + L+ + E + ++++FHR+ IG+ G IN +
Sbjct: 410 LE--GPTEDVNVA--QEQIEGMVKDLINRMDYVE-INIDHKFHRHLIGKSGANINRIKDQ 464
Query: 373 YNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPI 552
Y V V IPP ++ + I I+G + AK L EL ENE+ + +
Sbjct: 465 YKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENER--------TKDLIIEQ 516
Query: 553 VFHRKLIGQRGANIEMFRSKF-NVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMV 723
FHR +IGQ+G I R KF V I PD KS+ + +RG + +V+K + MV
Sbjct: 517 RFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMV 574
Score = 69.3 bits (168), Expect = 1e-11
Identities = 70/283 (24%), Positives = 126/283 (44%), Gaps = 42/283 (14%)
Frame = +1
Query: 1 HRNLITRNMTEIKNIQNSF-DVMIKFPN----RDISSKSG-------------------- 105
HR +I + I+ I++ F +V+I FP+ DI G
Sbjct: 519 HRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLV 578
Query: 106 ENGYD-------EAHLN--GNSDNTFVDTTEEGDSNVEAE-QNNPANWVALSGRRENCES 255
EN Y + H N G EE ++ ++ +N+ + + ++G+R NCE+
Sbjct: 579 ENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEA 638
Query: 256 AKEALL----ELVPVSE-DVPLNNEFHRNFIGQKGQGINTFSTKY-NVVVNIPPANKCLD 417
A+ +L +L ++E +V + + H + IG KG+ I + + V ++ P D
Sbjct: 639 ARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSD 698
Query: 418 FISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQRGANIE 597
+ I+GP +++ AK L L EKQ ++F + +H+ LIG+ G I
Sbjct: 699 TVVIRGPSSDVEKAKKQLLHL----AEEKQ---TKSFTVDIRAKPEYHKFLIGKGGGKIR 751
Query: 598 MFRSKFNVSIQIPDQNSKSEE-ITIRGYEEDVKKAEDELLSMV 723
R + P K ++ ITI G E+ V++A+ EL +++
Sbjct: 752 KVRDSTGARVIFPAAEDKDQDLITIIGKEDAVREAQKELEALI 794
Score = 63.2 bits (152), Expect = 8e-10
Identities = 43/149 (28%), Positives = 78/149 (52%), Gaps = 1/149 (0%)
Frame = +1
Query: 319 HRNFIGQKGQGINTFSTKY-NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWE 495
HR IG+KGQ + + + V + D I+++GP ++ A+ ++ ++
Sbjct: 376 HRFIIGKKGQNLAKITQQMPKVHIEFTEGE---DKITLEGPTEDVNVAQEQIEGMV---- 428
Query: 496 NEKQDRIARNFENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRG 675
+D I R ++ + FHR LIG+ GANI + ++ VS++IP + KS I I G
Sbjct: 429 ---KDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEG 485
Query: 676 YEEDVKKAEDELLSMVDRWKAQVIEELHI 762
+ V++A+ ELL + R + + ++L I
Sbjct: 486 DPQGVQQAKRELLELASRMENERTKDLII 514
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/194 (25%), Positives = 88/194 (45%), Gaps = 17/194 (8%)
Frame = +1
Query: 220 VALSGRRENCESAKEALLELVPVSE-------------DVPLNNEFHRNFIGQKGQGINT 360
+A++G N + AK LLE V + V ++ ++H IG+KG I
Sbjct: 1018 IAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQ 1077
Query: 361 FSTKYNVVVNIPP---ANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFE 531
+++V + P N+ D I+I G N A+ + L +V E E+
Sbjct: 1078 IRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAI--LRIVGELEQM------VS 1129
Query: 532 NQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEE-ITIRGYEEDVKKAEDE 708
VP+ H ++IG RG I +F V I+ P + +T+ G E+V++A D
Sbjct: 1130 EDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDH 1189
Query: 709 LLSMVDRWKAQVIE 750
+L++ + + A V++
Sbjct: 1190 ILNLEEEYLADVVD 1203
Score = 57.0 bits (136), Expect = 6e-08
Identities = 40/178 (22%), Positives = 87/178 (48%), Gaps = 6/178 (3%)
Frame = +1
Query: 193 AEQNNPANWVALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHRNFIGQKGQGIN 357
A ++ + + + G+ + A++ L L+ V + + ++ + HR+F+ ++GQ +
Sbjct: 765 AAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLR 824
Query: 358 TFSTKYN-VVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFEN 534
+ +Y V+V+ P + D +++KG + + AK + E+I + +
Sbjct: 825 EIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEII--------EDLEAQVTL 876
Query: 535 QVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDE 708
+ +P FHR ++G +G+ I+ F+V I+ PD+ EE + E V++ DE
Sbjct: 877 ECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDR----EENAVHSTEPVVQENGDE 930
Score = 55.5 bits (132), Expect = 2e-07
Identities = 47/198 (23%), Positives = 91/198 (45%), Gaps = 8/198 (4%)
Frame = +1
Query: 199 QNNPANWVALSGRRENCESAKEALLELVPVSE------DVPLNNEFHRNFIGQKGQGINT 360
+ + ++ V + G + E AK+ LL L + D+ E+H+ IG+ G I
Sbjct: 693 EGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRK 752
Query: 361 FSTKYNVVVNIPPA-NKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQ 537
V P A +K D I+I G + +A+ L+ LI +N +D +
Sbjct: 753 VRDSTGARVIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSML------ 806
Query: 538 VPVPIVFHRKLIGQRGANIEMFRSKFN-VSIQIPDQNSKSEEITIRGYEEDVKKAEDELL 714
V HR + +RG + ++ V + P ++S+++T++G ++ V+ A+ +
Sbjct: 807 --VDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQ 864
Query: 715 SMVDRWKAQVIEELHIPR 768
+++ +AQV E IP+
Sbjct: 865 EIIEDLEAQVTLECAIPQ 882
Score = 53.5 bits (127), Expect = 6e-07
Identities = 41/176 (23%), Positives = 82/176 (46%), Gaps = 6/176 (3%)
Frame = +1
Query: 202 NNPANWVALSGRRENCESAKEALLELVPVSED------VPLNNEFHRNFIGQKGQGINTF 363
++P+N + ++G +E E A+ +L L+ +D + + FH G + +
Sbjct: 190 DDPSNQIKITGTKEGIEKARHEVL-LISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEI 248
Query: 364 STKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVP 543
+ +NIPP + I G + L A A + + ++E +K+ + V
Sbjct: 249 MQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKK---IYEEKKK----KTTTIAVE 301
Query: 544 VPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDEL 711
V H+ +IG +G +++ + VS++IP +S SE + +RG E + +A E+
Sbjct: 302 VKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEV 357
Score = 50.4 bits (119), Expect = 5e-06
Identities = 40/168 (23%), Positives = 66/168 (39%), Gaps = 9/168 (5%)
Frame = +1
Query: 1 HRNLITRNMTEIKNIQNSFDVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTTEEGD 180
H +I R I I+ DV I+FP++D
Sbjct: 1064 HPKIIGRKGAVITQIRLEHDVNIQFPDKD------------------------------- 1092
Query: 181 SNVEAEQNNPANWVALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHRNFIGQKG 345
+ N P + + ++G +N E+A++A+L +V VSEDVPL++ H IG +G
Sbjct: 1093 -----DGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHARIIGARG 1147
Query: 346 QGINTFSTKYNVVVNIP----PANKCLDFISIKGPRANLIDAKAGLDE 477
+ I ++ V + P P C+ + ID L+E
Sbjct: 1148 KAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEE 1195
Score = 44.3 bits (103), Expect = 4e-04
Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 8/131 (6%)
Frame = +1
Query: 400 ANKCLDFISIKGPRANLIDAK--------AGLDELIVVWENEKQDRIARNFENQVPVPIV 555
A CL+ + G L AK +G + ++ + R+ V +P
Sbjct: 101 AKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKE 160
Query: 556 FHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWK 735
HR +IG+ G ++ K IQIP + S +I I G +E ++KA E+L +
Sbjct: 161 HHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQD 220
Query: 736 AQVIEELHIPR 768
+ +E L + +
Sbjct: 221 KRAVERLEVEK 231
>sp|Q8VDJ3|VIGLN_MOUSE Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 142 bits (359), Expect = 8e-34
Identities = 92/258 (35%), Positives = 143/258 (55%), Gaps = 6/258 (2%)
Frame = +1
Query: 1 HRNLITRNMTEIKNIQNSFDVMIKFPNRDISS-KSGENGYDEAHLNGNSDNTFVDTTEEG 177
HR+++ + I+ I ++V IKFP+R+ + S E E NG D EG
Sbjct: 885 HRSVMGPKGSRIQQITRDYNVQIKFPDREENPVHSVEPSIQE---NG-------DEAGEG 934
Query: 178 DSNVEAEQNNP--ANWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQKGQG 351
E + +P + + +SGR+E CE+AKEAL LVPV+ +V + + HR IGQKG G
Sbjct: 935 REAKETDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYIIGQKGSG 994
Query: 352 INTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFE 531
I ++ V +++P D I+I G ANL AKAGL + + + E++DR R+F+
Sbjct: 995 IRKMMDEFEVNIHVPAPELQSDTIAITGLAANLDRAKAGLLDRVKELQAEQEDRALRSFK 1054
Query: 532 NQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQ---NSKSEEITIRGYEEDVKKAE 702
V V +H K+IG++GA I R + V+IQ PD+ N ++ITI GYE++ + A
Sbjct: 1055 LSVTVDPKYHPKIIGRKGAVITQIRLEHEVNIQFPDKDDGNQPQDQITITGYEKNTEAAR 1114
Query: 703 DELLSMVDRWKAQVIEEL 756
D +L +V + V E++
Sbjct: 1115 DAILKIVGELEQMVSEDV 1132
Score = 89.0 bits (219), Expect = 1e-17
Identities = 56/192 (29%), Positives = 95/192 (49%), Gaps = 7/192 (3%)
Frame = +1
Query: 211 ANWVALSGRRENCESAKEALLELVPVSE-----DVPLNNEFHRNFIGQKGQGINTFSTKY 375
+N + + G + + AK LLEL E D+ + FHR IGQKG+ I K+
Sbjct: 478 SNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKF 537
Query: 376 -NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPI 552
V++N P + D + ++GP+ + + +++ D + ++ VP+
Sbjct: 538 PEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVA-------DLVENSYSISVPIFK 590
Query: 553 VFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRW 732
FH+ +IG+ GANI+ R + N I +P +NS SE I I G + + A +LS + +
Sbjct: 591 QFHKNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILS-IQKD 649
Query: 733 KAQVIE-ELHIP 765
A + E E+ IP
Sbjct: 650 LANIAEVEVSIP 661
Score = 80.9 bits (198), Expect = 4e-15
Identities = 68/235 (28%), Positives = 110/235 (46%), Gaps = 2/235 (0%)
Frame = +1
Query: 25 MTEIKNIQNSFDVM-IKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTTEEGDSNVEAEQ 201
+TE+ NSF V + P+ G+ G + A + ++ TE G+ + E
Sbjct: 354 LTEVYAKANSFTVSSVSAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTE-GEDKITLE- 411
Query: 202 NNPANWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQKGQGINTFSTKYNV 381
P V ++ +E E + L+ + E + ++++FHR+ IG+ G IN +Y V
Sbjct: 412 -GPTEDVNVA--QEQIEGMVKDLINRMDYVE-INIDHKFHRHLIGKSGANINRIKDQYKV 467
Query: 382 VVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFH 561
V IPP ++ + I I+G + AK L EL ENE+ + + FH
Sbjct: 468 SVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENER--------TKDLIIEQRFH 519
Query: 562 RKLIGQRGANIEMFRSKF-NVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMV 723
R +IGQ+G I R KF V I PD KS+ + +RG + +V+K + MV
Sbjct: 520 RTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMV 574
Score = 70.1 bits (170), Expect = 6e-12
Identities = 73/293 (24%), Positives = 131/293 (44%), Gaps = 42/293 (14%)
Frame = +1
Query: 1 HRNLITRNMTEIKNIQNSF-DVMIKFPN----RDISSKSG-------------------- 105
HR +I + I+ I++ F +V+I FP+ DI G
Sbjct: 519 HRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLV 578
Query: 106 ENGYD-------EAHLN--GNSDNTFVDTTEEGDSNVEAE-QNNPANWVALSGRRENCES 255
EN Y + H N G EE ++ ++ +N+ + + ++G+R NCE+
Sbjct: 579 ENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEA 638
Query: 256 AKEALL----ELVPVSE-DVPLNNEFHRNFIGQKGQGINTFSTKY-NVVVNIPPANKCLD 417
A+ +L +L ++E +V + + H + IG KG+ I + + V ++ P D
Sbjct: 639 ARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSD 698
Query: 418 FISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQRGANIE 597
+ I+GP +++ AK L L EKQ ++F + +H+ LIG+ G I
Sbjct: 699 TVVIRGPSSDVEKAKKQLLHL----AEEKQ---TKSFTVDIRAKPEYHKFLIGKGGGKIR 751
Query: 598 MFRSKFNVSIQIPDQNSKSEE-ITIRGYEEDVKKAEDELLSMVDRWKAQVIEE 753
R I P K ++ ITI G E+ V++A+ EL +++ + V+E+
Sbjct: 752 KVRDSTGARIIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLE-NVVED 803
Score = 63.2 bits (152), Expect = 8e-10
Identities = 43/149 (28%), Positives = 78/149 (52%), Gaps = 1/149 (0%)
Frame = +1
Query: 319 HRNFIGQKGQGINTFSTKY-NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWE 495
HR IG+KGQ + + + V + D I+++GP ++ A+ ++ ++
Sbjct: 376 HRFIIGKKGQNLAKITQQMPKVHIEFTEGE---DKITLEGPTEDVNVAQEQIEGMV---- 428
Query: 496 NEKQDRIARNFENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRG 675
+D I R ++ + FHR LIG+ GANI + ++ VS++IP + KS I I G
Sbjct: 429 ---KDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEG 485
Query: 676 YEEDVKKAEDELLSMVDRWKAQVIEELHI 762
+ V++A+ ELL + R + + ++L I
Sbjct: 486 DPQGVQQAKRELLELASRMENERTKDLII 514
Score = 61.6 bits (148), Expect = 2e-09
Identities = 52/194 (26%), Positives = 88/194 (45%), Gaps = 17/194 (8%)
Frame = +1
Query: 220 VALSGRRENCESAKEALL----ELVPVSED---------VPLNNEFHRNFIGQKGQGINT 360
+A++G N + AK LL EL ED V ++ ++H IG+KG I
Sbjct: 1018 IAITGLAANLDRAKAGLLDRVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQ 1077
Query: 361 FSTKYNVVVNIPP---ANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFE 531
++ V + P N+ D I+I G N A+ + L +V E E+
Sbjct: 1078 IRLEHEVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAI--LKIVGELEQM------VS 1129
Query: 532 NQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEE-ITIRGYEEDVKKAEDE 708
VP+ H ++IG RG I +F V I+ P + +T+ G E+V++A D
Sbjct: 1130 EDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDH 1189
Query: 709 LLSMVDRWKAQVIE 750
+L++ + + A V++
Sbjct: 1190 ILNLEEEYLADVVD 1203
Score = 58.2 bits (139), Expect = 2e-08
Identities = 42/178 (23%), Positives = 87/178 (48%), Gaps = 6/178 (3%)
Frame = +1
Query: 193 AEQNNPANWVALSGRRENCESAKEALLELVPVSEDVP-----LNNEFHRNFIGQKGQGIN 357
A ++ + + + G+ + A++ L L+ E+V ++ + HR+F+ ++GQ +
Sbjct: 765 AAEDKDQDLITIIGKEDAVREAQKELEALIQNLENVVEDYMLVDPKHHRHFVIRRGQVLR 824
Query: 358 TFSTKYN-VVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFEN 534
+ +Y V+V+ P + D +++KG + + AK + E+I E + A
Sbjct: 825 EIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTVECA----- 879
Query: 535 QVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDE 708
+P FHR ++G +G+ I+ +NV I+ PD+ EE + E +++ DE
Sbjct: 880 ---IPQKFHRSVMGPKGSRIQQITRDYNVQIKFPDR----EENPVHSVEPSIQENGDE 930
Score = 56.2 bits (134), Expect = 9e-08
Identities = 47/198 (23%), Positives = 91/198 (45%), Gaps = 8/198 (4%)
Frame = +1
Query: 199 QNNPANWVALSGRRENCESAKEALLELVPVSE------DVPLNNEFHRNFIGQKGQGINT 360
+ + ++ V + G + E AK+ LL L + D+ E+H+ IG+ G I
Sbjct: 693 EGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRK 752
Query: 361 FSTKYNVVVNIPPA-NKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQ 537
+ P A +K D I+I G + +A+ L+ LI EN +D +
Sbjct: 753 VRDSTGARIIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLENVVEDYML------ 806
Query: 538 VPVPIVFHRKLIGQRGANIEMFRSKFN-VSIQIPDQNSKSEEITIRGYEEDVKKAEDELL 714
V HR + +RG + ++ V + P ++S+++T++G ++ V+ A+ +
Sbjct: 807 --VDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQ 864
Query: 715 SMVDRWKAQVIEELHIPR 768
+++ +AQV E IP+
Sbjct: 865 EIIEDLEAQVTVECAIPQ 882
Score = 53.5 bits (127), Expect = 6e-07
Identities = 41/176 (23%), Positives = 82/176 (46%), Gaps = 6/176 (3%)
Frame = +1
Query: 202 NNPANWVALSGRRENCESAKEALLELVPVSED------VPLNNEFHRNFIGQKGQGINTF 363
++P+N + ++G +E E A+ +L L+ +D + + FH G + +
Sbjct: 190 DDPSNQIKITGTKEGIEKARHEVL-LISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEI 248
Query: 364 STKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVP 543
+ +NIPP + I G + L A A + + ++E +K+ + V
Sbjct: 249 MQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKK---IYEEKKK----KTTTIAVE 301
Query: 544 VPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDEL 711
V H+ +IG +G +++ + VS++IP +S SE + +RG E + +A E+
Sbjct: 302 VKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEV 357
Score = 50.1 bits (118), Expect = 7e-06
Identities = 29/101 (28%), Positives = 50/101 (49%), Gaps = 9/101 (8%)
Frame = +1
Query: 202 NNPANWVALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHRNFIGQKGQGINTFS 366
N P + + ++G +N E+A++A+L++V VSEDVPL++ H IG +G+ I
Sbjct: 1095 NQPQDQITITGYEKNTEAARDAILKIVGELEQMVSEDVPLDHRVHARIIGARGKAIRKIM 1154
Query: 367 TKYNVVVNIP----PANKCLDFISIKGPRANLIDAKAGLDE 477
++ V + P P C+ + ID L+E
Sbjct: 1155 DEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEE 1195
Score = 47.4 bits (111), Expect = 4e-05
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Frame = +1
Query: 400 ANKCLDFISIKGPRANLIDAK--------AGLDELIVVWENEKQDRIARNFENQVPVPIV 555
A CL+ + G L AK +G + ++ + R+ VP+P
Sbjct: 101 AKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVPIPKE 160
Query: 556 FHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWK 735
HR +IG+ G ++ K IQIP + S +I I G +E ++KA E+L +
Sbjct: 161 HHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQD 220
Query: 736 AQVIEELHIPR 768
+ +E L + +
Sbjct: 221 KRAVERLEVEK 231
Score = 38.5 bits (88), Expect = 0.020
Identities = 35/162 (21%), Positives = 67/162 (41%), Gaps = 2/162 (1%)
Frame = +1
Query: 220 VALSGRRENCESAKEALLELVPV--SEDVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNI 393
+ +SG+ + A++ ++ + S VP+ E HR IG+ G+ + K + I
Sbjct: 127 IMVSGKLDAVMKARKDIVARLQTQASATVPIPKEHHRFVIGKNGEKLQDLELKTATKIQI 186
Query: 394 PPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLI 573
P + + I I G + + KA + L++ E +K+ ++ V FH +
Sbjct: 187 PRPDDPSNQIKITGTKEGI--EKARHEVLLISAEQDKR------AVERLEVEKAFHPFIA 238
Query: 574 GQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKA 699
G + + I IP + EI G +E + +A
Sbjct: 239 GPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQA 280
>sp|Q9Z1A6|VIGLN_RAT Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 139 bits (351), Expect = 6e-33
Identities = 91/258 (35%), Positives = 142/258 (55%), Gaps = 6/258 (2%)
Frame = +1
Query: 1 HRNLITRNMTEIKNIQNSFDVMIKFPNRDISS-KSGENGYDEAHLNGNSDNTFVDTTEEG 177
HR+++ + I+ I ++V IKFP+R+ + S E E NG D EG
Sbjct: 885 HRSVMGPKGSRIQQITRDYNVQIKFPDREENPVHSVEPSIQE---NG-------DEAGEG 934
Query: 178 DSNVEAEQNNP--ANWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQKGQG 351
E + +P + + +SGR+E CE+AKEAL LVPV+ +V + + HR IGQKG G
Sbjct: 935 REAKETDPGSPRRCDIIVISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYIIGQKGSG 994
Query: 352 INTFSTKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFE 531
I ++ V +++P I+I G ANL AKAGL + + + E++DR R+F+
Sbjct: 995 IRKMMDEFEVNIHVPAPELQSHTIAITGLAANLDRAKAGLLDRVKELQAEQEDRALRSFK 1054
Query: 532 NQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQ---NSKSEEITIRGYEEDVKKAE 702
V V +H K+IG +GA I R + +V+IQ PD+ N ++ITI GYE++ + A
Sbjct: 1055 LSVTVDPKYHPKIIGGKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAAR 1114
Query: 703 DELLSMVDRWKAQVIEEL 756
D +L +V + V E++
Sbjct: 1115 DAILKIVGELEQMVSEDV 1132
Score = 87.8 bits (216), Expect = 3e-17
Identities = 55/192 (28%), Positives = 95/192 (49%), Gaps = 7/192 (3%)
Frame = +1
Query: 211 ANWVALSGRRENCESAKEALLELVPVSE-----DVPLNNEFHRNFIGQKGQGINTFSTKY 375
+N + + G + + AK LLEL E D+ + FHR IGQKG+ I K+
Sbjct: 478 SNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKF 537
Query: 376 -NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPI 552
V++N P + + + ++GP+ + + +++ D + ++ VP+
Sbjct: 538 PEVIINFPDPAQKSEIVQLRGPKNEVEKCTKYMQKMVA-------DLVENSYSISVPIFK 590
Query: 553 VFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRW 732
FH+ +IG+ GANI+ R + N I +P +NS SE I I G + + A +LS + +
Sbjct: 591 QFHKNIIGKGGANIKKIREESNTKIDLPAENSNSETIVITGKRANCEAARSRILS-IQKD 649
Query: 733 KAQVIE-ELHIP 765
A + E E+ IP
Sbjct: 650 LANIAEVEVSIP 661
Score = 82.0 bits (201), Expect = 2e-15
Identities = 69/235 (29%), Positives = 110/235 (46%), Gaps = 2/235 (0%)
Frame = +1
Query: 25 MTEIKNIQNSFDVM-IKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTTEEGDSNVEAEQ 201
+TE+ NSF V + P+ G+ G + A + ++ TE G+ + E
Sbjct: 354 LTEVYAKANSFTVSSVSAPSWLHRFIIGKKGQNLAKITHQMPKVHIEFTE-GEDKITLE- 411
Query: 202 NNPANWVALSGRRENCESAKEALLELVPVSEDVPLNNEFHRNFIGQKGQGINTFSTKYNV 381
P V ++ +E E + L+ + E + ++++FHR+ IG+ G IN +Y V
Sbjct: 412 -GPTEDVNVA--QEQIEGMVKDLINRMDYVE-INIDHKFHRHLIGKSGANINRIKDQYKV 467
Query: 382 VVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFH 561
V IPP ++ + I I+G + AK L EL ENE+ + + FH
Sbjct: 468 SVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENER--------TKDLIIEQRFH 519
Query: 562 RKLIGQRGANIEMFRSKF-NVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMV 723
R +IGQ+G I R KF V I PD KSE + +RG + +V+K + MV
Sbjct: 520 RTIIGQKGERIREIRDKFPEVIINFPDPAQKSEIVQLRGPKNEVEKCTKYMQKMV 574
Score = 68.6 bits (166), Expect = 2e-11
Identities = 59/234 (25%), Positives = 111/234 (47%), Gaps = 7/234 (2%)
Frame = +1
Query: 43 IQNSFDVMIKFPNRDISSKSGENGYDEAHLNGNSDNTFVDTTEEGDSNVEAEQNNPANWV 222
++NS+ + + + + G+ G + + S NT +D E N+ + +
Sbjct: 578 VENSYSISVPIFKQFHKNIIGKGGANIKKIREES-NTKIDLPAE---------NSNSETI 627
Query: 223 ALSGRRENCESAKEALL----ELVPVSE-DVPLNNEFHRNFIGQKGQGINTFSTKY-NVV 384
++G+R NCE+A+ +L +L ++E +V + + H + IG KG+ I + + V
Sbjct: 628 VITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVH 687
Query: 385 VNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHR 564
++ P D + I+GP +++ AK L L EKQ ++F + +H+
Sbjct: 688 IHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHL----AEEKQ---TKSFTVDIRAKPEYHK 740
Query: 565 KLIGQRGANIEMFRSKFNVSIQIPDQNSKSEE-ITIRGYEEDVKKAEDELLSMV 723
LIG+ G I R I P K ++ ITI G E+ V++A+ EL +++
Sbjct: 741 FLIGKGGGKIRKVRDSTGARIIFPAAEDKDQDLITIIGKEDAVREAQKELEALI 794
Score = 62.8 bits (151), Expect = 1e-09
Identities = 43/149 (28%), Positives = 78/149 (52%), Gaps = 1/149 (0%)
Frame = +1
Query: 319 HRNFIGQKGQGINTFSTKY-NVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWE 495
HR IG+KGQ + + + V + D I+++GP ++ A+ ++ ++
Sbjct: 376 HRFIIGKKGQNLAKITHQMPKVHIEFTEGE---DKITLEGPTEDVNVAQEQIEGMV---- 428
Query: 496 NEKQDRIARNFENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRG 675
+D I R ++ + FHR LIG+ GANI + ++ VS++IP + KS I I G
Sbjct: 429 ---KDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEG 485
Query: 676 YEEDVKKAEDELLSMVDRWKAQVIEELHI 762
+ V++A+ ELL + R + + ++L I
Sbjct: 486 DPQGVQQAKRELLELASRMENERTKDLII 514
Score = 57.4 bits (137), Expect = 4e-08
Identities = 42/178 (23%), Positives = 86/178 (48%), Gaps = 6/178 (3%)
Frame = +1
Query: 193 AEQNNPANWVALSGRRENCESAKEALLELVP----VSEDVPL-NNEFHRNFIGQKGQGIN 357
A ++ + + + G+ + A++ L L+ V ED L + HR+F+ ++GQ +
Sbjct: 765 AAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDYMLVDPRHHRHFVIRRGQVLR 824
Query: 358 TFSTKYN-VVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFEN 534
+ +Y V+V+ P + D +++KG + + AK + E+I + +
Sbjct: 825 EIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEII--------EDLEAQVTL 876
Query: 535 QVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDE 708
+ +P FHR ++G +G+ I+ +NV I+ PD+ EE + E +++ DE
Sbjct: 877 ECAIPQKFHRSVMGPKGSRIQQITRDYNVQIKFPDR----EENPVHSVEPSIQENGDE 930
Score = 54.3 bits (129), Expect = 4e-07
Identities = 46/198 (23%), Positives = 91/198 (45%), Gaps = 8/198 (4%)
Frame = +1
Query: 199 QNNPANWVALSGRRENCESAKEALLELVPVSE------DVPLNNEFHRNFIGQKGQGINT 360
+ + ++ V + G + E AK+ LL L + D+ E+H+ IG+ G I
Sbjct: 693 EGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRK 752
Query: 361 FSTKYNVVVNIPPA-NKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQ 537
+ P A +K D I+I G + +A+ L+ LI +N +D +
Sbjct: 753 VRDSTGARIIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDYML------ 806
Query: 538 VPVPIVFHRKLIGQRGANIEMFRSKFN-VSIQIPDQNSKSEEITIRGYEEDVKKAEDELL 714
V HR + +RG + ++ V + P ++S+++T++G ++ V+ A+ +
Sbjct: 807 --VDPRHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQ 864
Query: 715 SMVDRWKAQVIEELHIPR 768
+++ +AQV E IP+
Sbjct: 865 EIIEDLEAQVTLECAIPQ 882
Score = 53.5 bits (127), Expect = 6e-07
Identities = 41/176 (23%), Positives = 82/176 (46%), Gaps = 6/176 (3%)
Frame = +1
Query: 202 NNPANWVALSGRRENCESAKEALLELVPVSED------VPLNNEFHRNFIGQKGQGINTF 363
++P+N + ++G +E E A+ +L L+ +D + + FH G + +
Sbjct: 190 DDPSNQIKITGTKEGIEKARHEVL-LISAEQDKRAVKRLEVEKAFHPFIAGPYNRLVGEI 248
Query: 364 STKYNVVVNIPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVP 543
+ +NIPP + I G + L A A + + ++E +K+ + V
Sbjct: 249 MQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKK---IYEEKKK----KTTTIAVE 301
Query: 544 VPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDEL 711
V H+ +IG +G +++ + VS++IP +S SE + +RG E + +A E+
Sbjct: 302 VKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEV 357
Score = 51.2 bits (121), Expect = 3e-06
Identities = 46/181 (25%), Positives = 81/181 (44%), Gaps = 13/181 (7%)
Frame = +1
Query: 172 EGDSNVEA----EQNNPANWVALSGRRENCESAKEALLELVP-----VSEDVPLNNEFHR 324
E D N++ + N P + + ++G +N E+A++A+L++V VSEDVPL++ H
Sbjct: 1081 EHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILKIVGELEQMVSEDVPLDHRVHA 1140
Query: 325 NFIGQKGQGINTFSTKYNVVVNIP----PANKCLDFISIKGPRANLIDAKAGLDELIVVW 492
IG +G+ I ++ V + P P C +++ G N+ +A +D ++ +
Sbjct: 1141 RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNC---VTVTGLPENVEEA---IDHILNLE 1194
Query: 493 ENEKQDRIARNFENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIR 672
E D + P +G + N S + PD +S SEEI
Sbjct: 1195 EEYLADVVDSEALQVYMKPPAHEESKAPSKGFVVRDAPWTSNSSEKAPDMSS-SEEIPTF 1253
Query: 673 G 675
G
Sbjct: 1254 G 1254
Score = 45.8 bits (107), Expect = 1e-04
Identities = 32/131 (24%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Frame = +1
Query: 400 ANKCLDFISIKGPRANLIDAK--------AGLDELIVVWENEKQDRIARNFENQVPVPIV 555
A CL+ + G L AK +G + ++ + R+ VP+P
Sbjct: 101 AKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVPIPKE 160
Query: 556 FHRKLIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWK 735
HR +IG+ G ++ K IQIP + S +I I G +E ++KA E+L +
Sbjct: 161 HHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQD 220
Query: 736 AQVIEELHIPR 768
+ ++ L + +
Sbjct: 221 KRAVKRLEVEK 231
Score = 39.3 bits (90), Expect = 0.012
Identities = 37/162 (22%), Positives = 67/162 (41%), Gaps = 2/162 (1%)
Frame = +1
Query: 220 VALSGRRENCESAKEALLELVPV--SEDVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNI 393
+ +SG+ + A++ ++ + S VP+ E HR IG+ G+ + K + I
Sbjct: 127 IMVSGKLDAVMKARKDIVARLQTQASATVPIPKEHHRFVIGKNGEKLQDLELKTATKIQI 186
Query: 394 PPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLI 573
P + + I I G + + KA + L++ E +K R + E V FH +
Sbjct: 187 PRPDDPSNQIKITGTKEGI--EKARHEVLLISAEQDK--RAVKRLE----VEKAFHPFIA 238
Query: 574 GQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKA 699
G + + I IP + EI G +E + +A
Sbjct: 239 GPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQA 280
>sp|P06105|SC160_YEAST Protein SCP160 (Protein HX)
Length = 1222
Score = 61.2 bits (147), Expect = 3e-09
Identities = 67/297 (22%), Positives = 133/297 (44%), Gaps = 54/297 (18%)
Frame = +1
Query: 1 HRNLITRNMTEIKNIQNSFDVMIKFP--NRDISSKSGENGYDEAH--------------- 129
H +LI + T +Q ++V I FP N ++ + G ++AH
Sbjct: 724 HGSLIGPHGTYRNRLQEKYNVFINFPRDNEIVTIRGPSRGVNKAHEELKALLDFEMENGH 783
Query: 130 --------------LNGNSDNTFVDTTEEG--------DSNVEAEQNNPANWVALSGRRE 243
+ N DN E G ++ +A++ + ++G R+
Sbjct: 784 KMVINVPAEHVPRIIGKNGDNINDIRAEYGVEMDFLQKSTDPKAQETGEVE-LEITGSRQ 842
Query: 244 NCESAKEALLELVP-----VSEDVPLNNEFHRNFIGQKGQGINTFSTKY------NVVVN 390
N + A + + +V V+E + +++++H++ +G G + +K N V+
Sbjct: 843 NIKDAAKRVESIVAEASDFVTEVLKIDHKYHKSIVGSGGHILREIISKAGGEEIRNKSVD 902
Query: 391 IPPANKCLDFISIKGPRANLIDAKAGLDELIVVWENEKQDRIARNFENQVP--VPIVFHR 564
IP A+ I+++GP+ + K ++E+ ++I ++ EN V + I R
Sbjct: 903 IPNADSENKDITVQGPQKFV---KKVVEEI---------NKIVKDAENSVTKTIDIPAER 950
Query: 565 K--LIGQRGANIEMFRSKFNVSIQIPDQNSKSEEITIRGYEEDVKKAEDELLSMVDR 729
K LIG G S+FN+++ +P+++ S +ITI G E+V+KAE ++L+ + R
Sbjct: 951 KGALIGPGGIVRRQLESEFNINLFVPNKDDPSGKITITGAPENVEKAEKKILNEIIR 1007
Score = 54.3 bits (129), Expect = 4e-07
Identities = 59/232 (25%), Positives = 99/232 (42%), Gaps = 19/232 (8%)
Frame = +1
Query: 124 AHLNGNSDNTFVDTTEEGDSNVEA--EQNNPANW-----VALSGRRENCESAKEALLELV 282
A L GN + E+ ++ E+NN A+ V L+G N AK+ L
Sbjct: 647 ARLIGNKGSNLQQIREKFACQIDIPNEENNNASKDKTVEVTLTGLEYNLTHAKKYLAAEA 706
Query: 283 P-----VSEDVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNIPPANKCLDFISIKGPRAN 447
+++++ + +FH + IG G N KYNV +N P N + ++I+GP
Sbjct: 707 KKWADIITKELIVPVKFHGSLIGPHGTYRNRLQEKYNVFINFPRDN---EIVTIRGPSRG 763
Query: 448 LIDAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSI 627
+ A L L+ +E E ++ N VP ++IG+ G NI R+++ V +
Sbjct: 764 VNKAHEELKALL-DFEMENGHKMVIN------VPAEHVPRIIGKNGDNINDIRAEYGVEM 816
Query: 628 QI-------PDQNSKSEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEELHI 762
Q + E+ I G +++K A + S+V V E L I
Sbjct: 817 DFLQKSTDPKAQETGEVELEITGSRQNIKDAAKRVESIVAEASDFVTEVLKI 868
Score = 52.8 bits (125), Expect = 1e-06
Identities = 43/151 (28%), Positives = 66/151 (43%), Gaps = 7/151 (4%)
Frame = +1
Query: 295 DVPLNNEFHRNFIGQKGQGINTFSTKYNVVVNIP-------PANKCLDFISIKGPRANLI 453
++P N+ IG KG + K+ ++IP +K ++ +++ G NL
Sbjct: 640 NIPANSV--ARLIGNKGSNLQQIREKFACQIDIPNEENNNASKDKTVE-VTLTGLEYNLT 696
Query: 454 DAKAGLDELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQI 633
AK L W A ++ VP+ FH LIG G + K+NV I
Sbjct: 697 HAKKYLAAEAKKW--------ADIITKELIVPVKFHGSLIGPHGTYRNRLQEKYNVFINF 748
Query: 634 PDQNSKSEEITIRGYEEDVKKAEDELLSMVD 726
P N E +TIRG V KA +EL +++D
Sbjct: 749 PRDN---EIVTIRGPSRGVNKAHEELKALLD 776
Score = 45.8 bits (107), Expect = 1e-04
Identities = 24/82 (29%), Positives = 44/82 (53%), Gaps = 6/82 (7%)
Frame = +1
Query: 538 VPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNS------KSEEITIRGYEEDVKKA 699
V +P +LIG +G+N++ R KF I IP++ + K+ E+T+ G E ++ A
Sbjct: 639 VNIPANSVARLIGNKGSNLQQIREKFACQIDIPNEENNNASKDKTVEVTLTGLEYNLTHA 698
Query: 700 EDELLSMVDRWKAQVIEELHIP 765
+ L + +W + +EL +P
Sbjct: 699 KKYLAAEAKKWADIITKELIVP 720
>sp|O34374|YJIB_BACSU Putative cytochrome P450 yjiB
Length = 396
Score = 36.2 bits (82), Expect = 0.10
Identities = 24/94 (25%), Positives = 48/94 (51%)
Frame = +1
Query: 472 DELIVVWENEKQDRIARNFENQVPVPIVFHRKLIGQRGANIEMFRSKFNVSIQIPDQNSK 651
DELI ++ + + +F P+P++ +L+G A++E F++ ++ + P S+
Sbjct: 117 DELIQKFQGRSEFDLVHDFS--YPLPVIVISELLGVPSAHMEQFKAWSDLLVSTPKDKSE 174
Query: 652 SEEITIRGYEEDVKKAEDELLSMVDRWKAQVIEE 753
E + + E+ K E+EL + A +IEE
Sbjct: 175 EAE---KAFLEERDKCEEELAAFF----AGIIEE 201
>sp|Q12114|CHS5_YEAST Chitin biosynthesis protein CHS5 (Protein CAL3)
Length = 671
Score = 35.8 bits (81), Expect = 0.13
Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
Frame = +1
Query: 16 TRNMTEIKNIQNSFDVMIKFPNRDISSKS------GENGYD-EAHLNGNSDNTFVDTTEE 174
T N+ E K +S + +++ PN ++ S G+ D + H N +DN FV T E
Sbjct: 373 TPNIEENK-ADSSAEAVVEEPNEAVAESSPNEEATGQKSEDTDTHSNEQADNGFVQTEEV 431
Query: 175 GDSNV----EAEQNNPANWVALSGRRENCESAKEALLELVPVSEDVPLNNE 315
++N+ E N PA+ A+ R EA +E V+E + NE
Sbjct: 432 AENNITTESAGENNEPADDAAMEFGR------PEAEIETPEVNESIEDANE 476
>sp|Q9PWD6|HXA10_MORSA Homeobox protein Hox-A10
Length = 289
Score = 35.4 bits (80), Expect = 0.17
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 8/64 (12%)
Frame = +1
Query: 112 GYDEAHLNGNSDNTFVDTTEEGDSNVEAEQN-------NPANWV-ALSGRRENCESAKEA 267
G +EA + +++ + D TEE D +A+ N ANW+ A SGR++ C K
Sbjct: 167 GTEEARESSDAEVSSADETEEHDKERQAKSTKGDTKSENTANWLTAKSGRKKRCPYTKHQ 226
Query: 268 LLEL 279
LEL
Sbjct: 227 TLEL 230
>sp|P31260|HXA10_HUMAN Homeobox protein Hox-A10 (Hox-1H) (Hox-1.8) (PL)
Length = 393
Score = 33.5 bits (75), Expect = 0.66
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Frame = +1
Query: 76 PNRDISSKSGENGYDEAHLNGNSDNTFVDTTEEG-------DSNVEAEQNNPANWV-ALS 231
P S G G +EAH + ++ E DS ++ N ANW+ A S
Sbjct: 259 PTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSLGNSKGENAANWLTAKS 318
Query: 232 GRRENCESAKEALLEL 279
GR++ C K LEL
Sbjct: 319 GRKKRCPYTKHQTLEL 334
>sp|Q8CAS9|BAL_MOUSE B aggressive lymphoma protein homolog
Length = 866
Score = 33.1 bits (74), Expect = 0.86
Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 5/141 (3%)
Frame = +1
Query: 118 DEAHLNGNSDNTFVDTTEEGDSNVEAEQNNPANWVALSGRR--ENCESAKEALLELVPVS 291
+E +L+GNS + + E +PA + L G + E CE+ + LV +
Sbjct: 493 NELNLSGNSGALALQWSSGEQRRGGLEAGSPA--INLMGVKVGEMCEAQEWIERLLVSLD 550
Query: 292 EDVPLNNEFHRNFIGQKGQGINT---FSTKYNVVVNIPPANKCLDFISIKGPRANLIDAK 462
+ NN H ++G+K + + ST+ ++ + P L+ IKGP+A+LIDA
Sbjct: 551 HHIIENN--HILYLGKKEHDVLSELQTSTRVSISETVSPRTATLE---IKGPQADLIDAV 605
Query: 463 AGLDELIVVWENEKQDRIARN 525
++ ++ + E + +N
Sbjct: 606 MRIECMLCDVQEEVAGKREKN 626
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.314 0.133 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,536,006
Number of Sequences: 369166
Number of extensions: 1786323
Number of successful extensions: 4356
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4097
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4284
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7163732800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)