Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_E23
(748 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8CGF7|TCRG1_MOUSE Transcription elongation regulator 1 ... 130 3e-30
sp|O14776|TCRG1_HUMAN Transcription elongation regulator 1 ... 130 3e-30
sp|P34600|YO61_CAEEL Hypothetical protein ZK1098.1 in chrom... 49 1e-05
sp|Q9R1C7|FNBP3_MOUSE Formin-binding protein 3 (Formin-bind... 46 9e-05
sp|O75400|FNBP3_HUMAN Formin-binding protein 3 (Huntingtin ... 46 9e-05
sp|P49756|RBM25_HUMAN Probable RNA-binding protein 25 (RNA-... 46 1e-04
sp|Q8WXA9|SFR12_HUMAN Splicing factor, arginine/serine-rich... 45 2e-04
sp|Q8SX83|SPEN_DROME Split ends protein 44 5e-04
sp|P21127|CD2L1_HUMAN PITSLRE serine/threonine-protein kina... 43 0.001
sp|P37709|TRHY_RABIT Trichohyalin 43 0.001
>sp|Q8CGF7|TCRG1_MOUSE Transcription elongation regulator 1 (TATA box-binding
protein-associated factor 2S) (Transcription factor
CA150) (p144) (Formin-binding protein 28) (FBP 28)
Length = 1100
Score = 130 bits (328), Expect = 3e-30
Identities = 67/162 (41%), Positives = 108/162 (66%), Gaps = 1/162 (0%)
Frame = +3
Query: 264 VKQNYMILLKENKIYKIAHWTDAKKKIDSDQRYKAADSSK-REEWFKEFLKKNKTNSREN 440
+K ++ LL + + + W+ K K++SD RYKA DSS RE+ FK++++K N +
Sbjct: 797 IKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNL--D 854
Query: 441 SETKRDRERKERQEASIREREKEVKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIK 620
SE +++ ER+ R EAS+RERE+EV+++ S ++ D+ER+ H + EA Q FK LL+D+++
Sbjct: 855 SEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR 914
Query: 621 TSDDSWKEVKRVLRKDARWSDISDKLERPLRDSIFKEHINSL 746
+SD SW + +R LRKD RW + LER ++ +F EHI +L
Sbjct: 915 SSDVSWSDTRRTLRKDHRW-ESGSLLEREEKEKLFNEHIEAL 955
Score = 40.8 bits (94), Expect = 0.004
Identities = 40/182 (21%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Frame = +3
Query: 285 LLKENKIYKIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETK---- 452
+L E + + W KI D RY + +R++ F +++K R + K
Sbjct: 671 MLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQA 730
Query: 453 RDRERKERQEASIRERE-------KEVKESLSTA---MRDRD-----------KERDYHL 569
++ +K +EA R K K+S A M+DR+ K+
Sbjct: 731 KEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDS 790
Query: 570 KSEAEQL---FKVLLTDLIKTSDDSWKEVKRVLRKDARWSDISDKLERPLRDSIFKEHIN 740
K+ E++ F LL++ S W +VK + D R+ + +R+ +FK++I
Sbjct: 791 KTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSS---SMREDLFKQYIE 847
Query: 741 SL 746
+
Sbjct: 848 KI 849
>sp|O14776|TCRG1_HUMAN Transcription elongation regulator 1 (TATA box-binding
protein-associated factor 2S) (Transcription factor
CA150)
Length = 1098
Score = 130 bits (328), Expect = 3e-30
Identities = 67/162 (41%), Positives = 108/162 (66%), Gaps = 1/162 (0%)
Frame = +3
Query: 264 VKQNYMILLKENKIYKIAHWTDAKKKIDSDQRYKAADSSK-REEWFKEFLKKNKTNSREN 440
+K ++ LL + + + W+ K K++SD RYKA DSS RE+ FK++++K N +
Sbjct: 795 IKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNL--D 852
Query: 441 SETKRDRERKERQEASIREREKEVKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIK 620
SE +++ ER+ R EAS+RERE+EV+++ S ++ D+ER+ H + EA Q FK LL+D+++
Sbjct: 853 SEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR 912
Query: 621 TSDDSWKEVKRVLRKDARWSDISDKLERPLRDSIFKEHINSL 746
+SD SW + +R LRKD RW + LER ++ +F EHI +L
Sbjct: 913 SSDVSWSDTRRTLRKDHRW-ESGSLLEREEKEKLFNEHIEAL 953
Score = 40.8 bits (94), Expect = 0.004
Identities = 40/182 (21%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Frame = +3
Query: 285 LLKENKIYKIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETK---- 452
+L E + + W KI D RY + +R++ F +++K R + K
Sbjct: 669 MLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQA 728
Query: 453 RDRERKERQEASIRERE-------KEVKESLSTA---MRDRD-----------KERDYHL 569
++ +K +EA R K K+S A M+DR+ K+
Sbjct: 729 KEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDS 788
Query: 570 KSEAEQL---FKVLLTDLIKTSDDSWKEVKRVLRKDARWSDISDKLERPLRDSIFKEHIN 740
K+ E++ F LL++ S W +VK + D R+ + +R+ +FK++I
Sbjct: 789 KTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSS---SMREDLFKQYIE 845
Query: 741 SL 746
+
Sbjct: 846 KI 847
>sp|P34600|YO61_CAEEL Hypothetical protein ZK1098.1 in chromosome III
Length = 724
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/113 (30%), Positives = 59/113 (52%), Gaps = 15/113 (13%)
Frame = +3
Query: 264 VKQNYMILLKENKIYKIAHWTDAKKKIDSDQRYKAADS-SKREEWFKEFLKKNKTNSR-- 434
++ + LLKE+ + K + WT K KI+ D+ Y A ++ +RE F + KN T+
Sbjct: 581 LESEFRNLLKEHNVDKDSEWTVIKPKIEKDKAYLAMENDDERETAFNHY--KNGTSGTTA 638
Query: 435 -----ENSETKRDRERKERQ-------EASIREREKEVKESLSTAMRDRDKER 557
E + K+D+++K ++ E IRE+EK+ K+ S R D+ER
Sbjct: 639 GSEILEKKKKKKDKKKKNKRSDNNSESEGEIREKEKKKKKKHSKEDRMDDEER 691
>sp|Q9R1C7|FNBP3_MOUSE Formin-binding protein 3 (Formin-binding protein 11) (FBP 11)
Length = 953
Score = 46.2 bits (108), Expect = 9e-05
Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
Frame = +3
Query: 267 KQNYMILLKENKIYKIAHWTDAKKKIDSDQRYKA-ADSSKREEWFKEFLKKNKTNSRENS 443
KQ + LLKE ++ A W A K I +D RY A A S++++ F +
Sbjct: 393 KQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAY------------ 440
Query: 444 ETKRDRERKERQEASIREREKEVKESLSTAMRDRDKERDYHLKSEAEQLF 593
K E++E++EA R + KE KES + + +K +AEQ+F
Sbjct: 441 --KVQTEKEEKEEA--RSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMF 486
Score = 33.1 bits (74), Expect = 0.81
Identities = 22/77 (28%), Positives = 37/77 (48%)
Frame = +3
Query: 330 AKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRERKERQEASIREREKE 509
+KKK + + A++ S E + + K S+++ + + R K S EREK+
Sbjct: 837 SKKKRQRSESHSASERSSSAESERSYKK-----SKKHKKKSKKRRHKSDSPESDTEREKD 891
Query: 510 VKESLSTAMRDRDKERD 560
KE +DRD E+D
Sbjct: 892 KKE------KDRDSEKD 902
>sp|O75400|FNBP3_HUMAN Formin-binding protein 3 (Huntingtin yeast partner A)
(Huntingtin-interacting protein HYPA/FBP11) (Fas-ligand
associated factor 1) (NY-REN-6 antigen)
Length = 957
Score = 46.2 bits (108), Expect = 9e-05
Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
Frame = +3
Query: 267 KQNYMILLKENKIYKIAHWTDAKKKIDSDQRYKA-ADSSKREEWFKEFLKKNKTNSRENS 443
KQ + LLKE ++ A W A K I +D RY A A S++++ F +
Sbjct: 397 KQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAY------------ 444
Query: 444 ETKRDRERKERQEASIREREKEVKESLSTAMRDRDKERDYHLKSEAEQLF 593
K E++E++EA R + KE KES + + +K +AEQ+F
Sbjct: 445 --KVQTEKEEKEEA--RSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMF 490
Score = 31.2 bits (69), Expect = 3.1
Identities = 20/75 (26%), Positives = 36/75 (48%)
Frame = +3
Query: 333 KKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRERKERQEASIREREKEV 512
KK+ S+ R + SS E +++ S+++ + + R K S EREK+
Sbjct: 843 KKRQRSESRSASEHSSSAES------ERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDK 896
Query: 513 KESLSTAMRDRDKER 557
KE + +DR ++R
Sbjct: 897 KEKDRESEKDRTRQR 911
>sp|P49756|RBM25_HUMAN Probable RNA-binding protein 25 (RNA-binding motif protein 25)
(RNA-binding region containing protein 7) (Protein S164)
Length = 784
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 6/90 (6%)
Frame = +3
Query: 309 KIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRER---KERQ 479
+I+ + D KK++ + K +R+E KE ++ + RE +R+RER +ER+
Sbjct: 221 EISKFRDTHKKLEEE---KGKKEKERQEIEKERRERERERERERERRERERERERERERE 277
Query: 480 EASIREREKE---VKESLSTAMRDRDKERD 560
+ RERE+E ++ RDRD+ERD
Sbjct: 278 KEKERERERERDRDRDRTKERDRDRDRERD 307
Score = 35.8 bits (81), Expect = 0.13
Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 6/84 (7%)
Frame = +3
Query: 327 DAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENS-----ETKRDRER-KERQEAS 488
D K+ D D+ + RE K+++ SRE S E +R+RER +ER+
Sbjct: 293 DRTKERDRDRDRERDRDRDRER--SSDRNKDRSRSREKSRDRERERERERERERERERER 350
Query: 489 IREREKEVKESLSTAMRDRDKERD 560
RERE+E +E R++DK+RD
Sbjct: 351 ERERERE-REREREREREKDKKRD 373
Score = 35.4 bits (80), Expect = 0.16
Identities = 19/70 (27%), Positives = 38/70 (54%)
Frame = +3
Query: 378 SKREEWFKEFLKKNKTNSRENSETKRDRERKERQEASIREREKEVKESLSTAMRDRDKER 557
SK + K+ ++ +E E +++R +ER+ RERE+E +E R+R++E+
Sbjct: 223 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERE----RERERERREREREREREREREK 278
Query: 558 DYHLKSEAEQ 587
+ + E E+
Sbjct: 279 EKERERERER 288
Score = 35.0 bits (79), Expect = 0.21
Identities = 24/104 (23%), Positives = 49/104 (47%)
Frame = +3
Query: 276 YMILLKENKIYKIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKR 455
Y ++ KE+ + K+ + S + K D+ K+ E + +E +
Sbjct: 197 YPLITKED--INAIEMEEDKRDLISREISKFRDTHKKLE--------EEKGKKEKERQEI 246
Query: 456 DRERKERQEASIREREKEVKESLSTAMRDRDKERDYHLKSEAEQ 587
++ER+ER+ RERE+ +E R+R+KE++ + E ++
Sbjct: 247 EKERRERERERERERERREREREREREREREKEKERERERERDR 290
Score = 33.1 bits (74), Expect = 0.81
Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 9/109 (8%)
Frame = +3
Query: 288 LKENKIYKIAHWTDAKKKIDSDQRYKAADSSKRE-EWFKEFLKKNKTNSRENSETKRDRE 464
L+E K K + +K+ +R + + +RE E +E ++ + E +RDR+
Sbjct: 232 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRD 291
Query: 465 R---KERQEASIREREKEVKESLST-----AMRDRDKERDYHLKSEAEQ 587
R KER RER+++ S+ R R+K RD + E E+
Sbjct: 292 RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERER 340
Score = 31.6 bits (70), Expect = 2.4
Identities = 33/152 (21%), Positives = 71/152 (46%), Gaps = 10/152 (6%)
Frame = +3
Query: 291 KENKIYKIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLK-KNKTNSRENSETK---RD 458
+ +I K + +++ + ++R + + + E KE + + + R+ TK RD
Sbjct: 242 ERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRD 301
Query: 459 RER-----KERQEASIREREK-EVKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIK 620
R+R ++R+ +S R +++ +E R+R++ER+ + E E+ + +
Sbjct: 302 RDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERE 361
Query: 621 TSDDSWKEVKRVLRKDARWSDISDKLERPLRD 716
+ K+ KR +D + KLER LR+
Sbjct: 362 REREREKDKKRDREEDEEDAYERRKLERKLRE 393
Score = 30.4 bits (67), Expect = 5.3
Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 23/108 (21%)
Frame = +3
Query: 333 KKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENS-----ETKRDRER---------- 467
+ K S R K+ D + E +E ++ + RE E +R+RER
Sbjct: 318 RNKDRSRSREKSRDRERERERERE-REREREREREREREREREREREREREKDKKRDREE 376
Query: 468 -------KERQEASIREREKEVKESLST-AMRDRDKERDYHLKSEAEQ 587
+ + E +RE+E +E L +R+R K R+Y ++E E+
Sbjct: 377 DEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREE 424
>sp|Q8WXA9|SFR12_HUMAN Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich
splicing regulatory protein 86) (SRrp86) (Splicing
regulatory protein 508) (SRrp508)
Length = 508
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/88 (30%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Frame = +3
Query: 327 DAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRER-KERQEASIRERE 503
D ++KI +R K D K E KE K+ + ++ + +R+++R K++++ RERE
Sbjct: 263 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 322
Query: 504 KEVKESLSTAMRDRDKERDYHLKSEAEQ 587
KE + +DRDKE++ E E+
Sbjct: 323 KEHE-------KDRDKEKEKEQDKEKER 343
Score = 37.0 bits (84), Expect = 0.056
Identities = 28/85 (32%), Positives = 45/85 (52%)
Frame = +3
Query: 333 KKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRERKERQEASIREREKEV 512
KK+ S +R K+ S + K+ +K K R ++DRE KER+ RE+EKE
Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK---EKDRE-KEREREKEREKEKER 295
Query: 513 KESLSTAMRDRDKERDYHLKSEAEQ 587
++ +DRDKER+ + + E+
Sbjct: 296 GKN-----KDRDKEREKDREKDKEK 315
Score = 33.5 bits (75), Expect = 0.62
Identities = 16/65 (24%), Positives = 33/65 (50%)
Frame = +3
Query: 354 QRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRERKERQEASIREREKEVKESLSTA 533
+R ++ SS+ K +K+ + S K+D++R++ ++ RE+E S+ +
Sbjct: 382 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 441
Query: 534 MRDRD 548
DRD
Sbjct: 442 SNDRD 446
Score = 32.7 bits (73), Expect = 1.1
Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
Frame = +3
Query: 348 SDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKR---DRER-KERQEASIREREKEVK 515
S R K + S R + K R S K+ RER K R + R++ K+ +
Sbjct: 206 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR 265
Query: 516 ESLSTAMR----DRDKERDYHLKSEAEQ 587
E + R DR+KER+ + E E+
Sbjct: 266 EKIKEKERVKEKDREKEREREKEREKEK 293
Score = 31.6 bits (70), Expect = 2.4
Identities = 20/78 (25%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Frame = +3
Query: 330 AKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRERKERQEASIRERE-- 503
++ K D + + S+R E ++ T+ R++S + +E+ E+ S++E+E
Sbjct: 411 SRNKKDKKREKERDHISERRE------RERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHN 464
Query: 504 KEVKESLSTAMRDRDKER 557
KE S+S + D+D R
Sbjct: 465 KEPDSSVSKEVDDKDAPR 482
>sp|Q8SX83|SPEN_DROME Split ends protein
Length = 5560
Score = 43.9 bits (102), Expect = 5e-04
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 3/138 (2%)
Frame = +3
Query: 327 DAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRERKERQEASIREREK 506
D K + +QR++ ++E+ K+ K+ + RE + K +E +E+++ +E EK
Sbjct: 1912 DTADKAEKNQRHEKEKKERQEKREKDLRKQVE---REEKDRKAQQEEREKEDRKAKEEEK 1968
Query: 507 EVKESLSTAMRDRD-KERDYHLKSEAEQLFKVLLTDLIKTSDDSWKEVKRVLRKDARWSD 683
E +E A DR+ KER+ E EQ K I+ D KE + +D R +
Sbjct: 1969 E-REREKKAQEDREKKEREERELREKEQRDKEQKEKEIREKDLREKEQR---ERDNREKE 2024
Query: 684 ISDK--LERPLRDSIFKE 731
+ DK E+ +R+ +E
Sbjct: 2025 LRDKDLREKEMREKEQRE 2042
Score = 43.1 bits (100), Expect = 8e-04
Identities = 35/137 (25%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Frame = +3
Query: 291 KENKIYKIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENS--ETKRDRE 464
KE K + D +K+++ +++ + A +RE+ ++ ++ K RE E + +E
Sbjct: 1925 KEKKERQEKREKDLRKQVEREEKDRKAQQEEREKEDRKAKEEEKEREREKKAQEDREKKE 1984
Query: 465 RKERQEASIREREKEVKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIKTSDDSWKE 644
R+ER+ +R+KE KE R+KE+ E E K L ++ + KE
Sbjct: 1985 REERELREKEQRDKEQKEKEIREKDLREKEQRERDNREKELRDKDLREKEMREKEQREKE 2044
Query: 645 VKRVLRKDARWSDISDK 695
+ R KD R + +K
Sbjct: 2045 LHR--EKDQREREHREK 2059
Score = 40.8 bits (94), Expect = 0.004
Identities = 38/156 (24%), Positives = 72/156 (46%), Gaps = 9/156 (5%)
Frame = +3
Query: 291 KENKIYKIAHWTDAKKKIDSDQRYKAA-----DSSKREEWFKEFLKKNKTNSRENSETKR 455
K K K A +D +K + Q K+A D S + + +KN+ + +E E +
Sbjct: 1873 KIKKSDKNASSSDKRKNSSTSQSSKSATPRIEDDSSEADDTADKAEKNQRHEKEKKERQE 1932
Query: 456 DRERKERQEASIREREK----EVKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIKT 623
RE+ R++ E+++ E +E ++ +KER+ K++ ++ K ++
Sbjct: 1933 KREKDLRKQVEREEKDRKAQQEEREKEDRKAKEEEKEREREKKAQEDREKKEREERELRE 1992
Query: 624 SDDSWKEVKRVLRKDARWSDISDKLERPLRDSIFKE 731
+ KE K K+ R D+ +K +R RD+ KE
Sbjct: 1993 KEQRDKEQK---EKEIREKDLREKEQRE-RDNREKE 2024
Score = 32.3 bits (72), Expect = 1.4
Identities = 23/97 (23%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Frame = +3
Query: 327 DAKKKIDSDQRYKAADSSKREEWFKEF----LKKNKTNSRENSETK-RDRERKERQEASI 491
D +KK ++ + + +E+ KE L++ + R+N E + RD++ +E++
Sbjct: 1979 DREKKEREERELREKEQRDKEQKEKEIREKDLREKEQRERDNREKELRDKDLREKEMREK 2038
Query: 492 REREKEVKESLSTAMRDRD-KERDYHLKSEAEQLFKV 599
+REKE+ R++D +ER++ K ++ + V
Sbjct: 2039 EQREKELH-------REKDQREREHREKEQSRRAMDV 2068
>sp|P21127|CD2L1_HUMAN PITSLRE serine/threonine-protein kinase CDC2L1
(Galactosyltransferase-associated protein kinase
p58/GTA) (Cell division cycle 2-like protein kinase 1)
(CLK-1) (CDK11) (p58 CLK-1)
Length = 795
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = +3
Query: 309 KIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDR----ERKER 476
K A + +++ + +R++ R EW ++ K + +RE+S +RDR ERK
Sbjct: 120 KHARVKEKEREHERRKRHREEQDKARREWERQ---KRREMAREHSRRERDRLEQLERKRE 176
Query: 477 QEASIREREKEVKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTD 611
+E +RE++KE +E R ++ ++ + E + + D
Sbjct: 177 RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED 221
Score = 34.3 bits (77), Expect = 0.36
Identities = 30/116 (25%), Positives = 56/116 (48%), Gaps = 14/116 (12%)
Frame = +3
Query: 288 LKENKIYKIAHWTDAKKKIDSDQRYKAADS--------SKREEWFKEFLKKNKTNSRENS 443
LKE K+ + +D + DS+++ +A+S S+ EE +E ++ + S E+
Sbjct: 265 LKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 324
Query: 444 ETKRDRERKER------QEASIREREKEVKESLSTAMRDRDKERDYHLKSEAEQLF 593
E + + E +E +EAS + E+ +E +S D ++E + HL E F
Sbjct: 325 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS---EDEERENENHLLVVPESRF 377
>sp|P37709|TRHY_RABIT Trichohyalin
Length = 1407
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/128 (22%), Positives = 70/128 (54%)
Frame = +3
Query: 333 KKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRERKERQEASIREREKEV 512
K++ + ++ Y+ + +REE K ++ + RE E +++ + ++R+ +RE E+ +
Sbjct: 557 KRRQEREREYREEEKLQREEDEKRRRQERERQYRELEELRQEEQLRDRK---LREEEQLL 613
Query: 513 KESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIKTSDDSWKEVKRVLRKDARWSDISD 692
+E +R +++ER E EQL + +L + + +E +++LR++ + ++
Sbjct: 614 QEREEERLRRQERERKLR---EEEQLLRQEEQELRQERERKLREEEQLLRREEQ--ELRQ 668
Query: 693 KLERPLRD 716
+ ER LR+
Sbjct: 669 ERERKLRE 676
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/145 (24%), Positives = 75/145 (51%), Gaps = 1/145 (0%)
Frame = +3
Query: 285 LLKENKIYKIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRE 464
LL+E + ++ +K + +Q + + R+E ++ ++ + RE E +++RE
Sbjct: 612 LLQEREEERLRRQERERKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQELRQERE 671
Query: 465 RKERQEAS-IREREKEVKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIKTSDDSWK 641
RK R+E ++ERE+E R R +ER L+ E EQL + +L + + +
Sbjct: 672 RKLREEEQLLQEREEE---------RLRRQERARKLREE-EQLLRQEEQELRQERERKLR 721
Query: 642 EVKRVLRKDARWSDISDKLERPLRD 716
E +++LR++ + + + +R LR+
Sbjct: 722 EEEQLLRREEQL--LRQERDRKLRE 744
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/129 (24%), Positives = 64/129 (49%), Gaps = 1/129 (0%)
Frame = +3
Query: 330 AKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRERKERQEAS-IREREK 506
A+K + +Q + + R+E ++F ++ + RE E +R+R+RK R+E ++ERE+
Sbjct: 1213 ARKLREEEQLLRQEEQELRQERDRKFREEEQLLRREEQELRRERDRKFREEEQLLQEREE 1272
Query: 507 EVKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIKTSDDSWKEVKRVLRKDARWSDI 686
E A + R++E + + EQ + + D ++ ++ R++
Sbjct: 1273 ERLRRQERARKLREEEEQLLFEEQEEQRLR-------QERDRRYRAEEQFAREEK----- 1320
Query: 687 SDKLERPLR 713
S +LER LR
Sbjct: 1321 SRRLERELR 1329
Score = 39.7 bits (91), Expect = 0.009
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 1/123 (0%)
Frame = +3
Query: 381 KREEWFKEFLKKNKTNSRENSETKRDRERKERQEAS-IREREKEVKESLSTAMRDRDKER 557
+R+E ++ ++ + RE E +R+R RK R+E ++ERE+E R R +ER
Sbjct: 928 RRQERERKLREEEQLLRREEQELRRERARKLREEEQLLQEREEE---------RLRRQER 978
Query: 558 DYHLKSEAEQLFKVLLTDLIKTSDDSWKEVKRVLRKDARWSDISDKLERPLRDSIFKEHI 737
L+ E EQL + +L + D ++E +++L++ ++L R RD F+E
Sbjct: 979 ARKLREE-EQLLRREEQELRQERDRKFREEEQLLQERE-----EERLRRQERDRKFREEE 1032
Query: 738 NSL 746
L
Sbjct: 1033 RQL 1035
Score = 39.7 bits (91), Expect = 0.009
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
Frame = +3
Query: 381 KREEWFKEFLKKNKTNSRENSETKRDRERKERQEAS-IREREKEVKESLSTAMRDRDKER 557
+R+E ++ ++ + RE E +++R+RK R+E ++ERE+E R R +ER
Sbjct: 974 RRQERARKLREEEQLLRREEQELRQERDRKFREEEQLLQEREEE---------RLRRQER 1024
Query: 558 DYHLKSEAEQLFKVLLTDLIKTSDDSWKEVKRVLRKDARWSDISDKLERPLRDSIFKE 731
D + E QL + L + + D ++ +R++ +L R RD F+E
Sbjct: 1025 DRKFREEERQLRRQELEEQFRQERDRKFRLEEQIRQEKE----EKQLRRQERDRKFRE 1078
Score = 38.1 bits (87), Expect = 0.025
Identities = 28/116 (24%), Positives = 56/116 (48%), Gaps = 14/116 (12%)
Frame = +3
Query: 285 LLKENKIYKIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRE 464
LL+E + ++ A+K + +Q + + R+E ++ ++ + +E E +++R+
Sbjct: 1176 LLQEREEERLRRQERARKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELRQERD 1235
Query: 465 RKERQEASI---------REREKEVKESLSTAM-----RDRDKERDYHLKSEAEQL 590
RK R+E + RER+++ +E R R +ER L+ E EQL
Sbjct: 1236 RKFREEEQLLRREEQELRRERDRKFREEEQLLQEREEERLRRQERARKLREEEEQL 1291
Score = 37.7 bits (86), Expect = 0.033
Identities = 23/102 (22%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
Frame = +3
Query: 285 LLKENKIYKIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRE 464
LL+E + ++ +K + +Q + + R+E ++ ++ + +E E +++R+
Sbjct: 828 LLQEREEERLRRQERERKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELRQERD 887
Query: 465 RKERQEAS-IREREKEVKESLSTAMRDRDKERDYHLKSEAEQ 587
RK R+E +R+ E+E+++ RDR + L E+E+
Sbjct: 888 RKLREEEQLLRQEEQELRQE-----RDRKLREEEQLLQESEE 924
Score = 36.2 bits (82), Expect = 0.096
Identities = 23/104 (22%), Positives = 52/104 (50%)
Frame = +3
Query: 285 LLKENKIYKIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRE 464
LL+E + ++ A+K + +Q + + R+E ++ ++ + RE +++R+
Sbjct: 680 LLQEREEERLRRQERARKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQLLRQERD 739
Query: 465 RKERQEASIREREKEVKESLSTAMRDRDKERDYHLKSEAEQLFK 596
RK R+E + + +E R R +ER+ L+ E ++ F+
Sbjct: 740 RKLREEEQLLQESEE--------ERLRRQEREQQLRRERDRKFR 775
Score = 36.2 bits (82), Expect = 0.096
Identities = 29/129 (22%), Positives = 64/129 (49%), Gaps = 5/129 (3%)
Frame = +3
Query: 345 DSDQRYKAADS---SKREEWFKEFLKKNKTNSRENSETKRDRERKERQ--EASIREREKE 509
+ D++++ + + EE + ++ K E +R+ ER RQ E +RE E+
Sbjct: 769 ERDRKFREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQERERKLREEEQL 828
Query: 510 VKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIKTSDDSWKEVKRVLRKDARWSDIS 689
++E +R +++ER E EQL + +L + +E +++LR++ + ++
Sbjct: 829 LQEREEERLRRQERERKLR---EEEQLLRQEEQELRQERARKLREEEQLLRQEEQ--ELR 883
Query: 690 DKLERPLRD 716
+ +R LR+
Sbjct: 884 QERDRKLRE 892
Score = 36.2 bits (82), Expect = 0.096
Identities = 34/129 (26%), Positives = 66/129 (51%), Gaps = 1/129 (0%)
Frame = +3
Query: 333 KKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRERKERQEASI-REREKE 509
+++I ++ K +R+ F+E ++ + RE + +R+R+RK R+E + +ERE+E
Sbjct: 1055 EEQIRQEKEEKQLRRQERDRKFREEEQQRRRQEREQ-QLRRERDRKFREEEQLLQEREEE 1113
Query: 510 VKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIKTSDDSWKEVKRVLRKDARWSDIS 689
R R +ER L+ E EQL + L + D ++E +++L++
Sbjct: 1114 ---------RLRRQERARKLREE-EQLLRREEQLLRQERDRKFREEEQLLQESEEERLRR 1163
Query: 690 DKLERPLRD 716
+ ER LR+
Sbjct: 1164 QERERKLRE 1172
Score = 35.8 bits (81), Expect = 0.13
Identities = 22/72 (30%), Positives = 37/72 (51%)
Frame = +3
Query: 345 DSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRERKERQEASIREREKEVKESL 524
+ D+RY+A + REE K + + E +R+RERK R+E R++E+E +
Sbjct: 1304 ERDRRYRAEEQFAREE--KSRRLERELRQEEEQRRRRERERKFREEQLRRQQEEEQRR-- 1359
Query: 525 STAMRDRDKERD 560
+R+R D
Sbjct: 1360 -RQLRERQFRED 1370
Score = 34.7 bits (78), Expect = 0.28
Identities = 25/112 (22%), Positives = 58/112 (51%)
Frame = +3
Query: 330 AKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRERKERQEASIREREKE 509
A+K + +Q + + R+E ++ ++ + +E E +++R+RK +RE E+
Sbjct: 865 ARKLREEEQLLRQEEQELRQERDRKLREEEQLLRQEEQELRQERDRK------LREEEQL 918
Query: 510 VKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIKTSDDSWKEVKRVLRK 665
++ES +R +++ER E EQL + +L + +E +++L++
Sbjct: 919 LQESEEERLRRQERERKLR---EEEQLLRREEQELRRERARKLREEEQLLQE 967
Score = 34.3 bits (77), Expect = 0.36
Identities = 32/144 (22%), Positives = 65/144 (45%)
Frame = +3
Query: 285 LLKENKIYKIAHWTDAKKKIDSDQRYKAADSSKREEWFKEFLKKNKTNSRENSETKRDRE 464
LL+E + ++ +K + +Q + + EE + ++ K E +R+ E
Sbjct: 780 LLQEREEERLRRQERERKLREEEQLLQ----EREEERLRRQERERKLREEEQLLQEREEE 835
Query: 465 RKERQEASIREREKEVKESLSTAMRDRDKERDYHLKSEAEQLFKVLLTDLIKTSDDSWKE 644
R RQE RER+ +E L ++ E EQL + +L + D +E
Sbjct: 836 RLRRQE---RERKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELRQERDRKLRE 892
Query: 645 VKRVLRKDARWSDISDKLERPLRD 716
+++LR++ + ++ + +R LR+
Sbjct: 893 EEQLLRQEEQ--ELRQERDRKLRE 914
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/118 (22%), Positives = 61/118 (51%), Gaps = 6/118 (5%)
Frame = +3
Query: 381 KREEWFKEFLKKNKTNSRENSETKRDRE----RKERQEASIREREKEVKESLSTAMRDRD 548
+R+E ++ ++ RE + ++RE R++ +E +RE E+ ++E +R ++
Sbjct: 758 RRQEREQQLRRERDRKFREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQE 817
Query: 549 KERDYHLKSEAEQLFKVLLTDLIKTSDDSWK--EVKRVLRKDARWSDISDKLERPLRD 716
+ER E EQL + + ++ + K E +++LR++ + ++ + R LR+
Sbjct: 818 RERKLR---EEEQLLQEREEERLRRQERERKLREEEQLLRQEEQ--ELRQERARKLRE 870
Score = 32.3 bits (72), Expect = 1.4
Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Frame = +3
Query: 399 KEFLKKNKTNSRENSETKRDRERKERQEASIRERE----KEVKESLSTAMRDRDKERD-Y 563
+EF+++ + RE E KR+ +E+Q RE+ +E +E L R R++ R+
Sbjct: 198 EEFIEEEQLRRREQQELKRELREEEQQRRERREQHERALQEEEEQLLRQRRWREEpreQQ 257
Query: 564 HLKSEAEQL 590
L+ E E++
Sbjct: 258 QLRRELEEI 266
Score = 32.0 bits (71), Expect = 1.8
Identities = 32/115 (27%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
Frame = +3
Query: 384 REEWFKEFLKKNKTNSRE-NSETKRDRERKERQEASIRERE-KEVKESLSTAMRDRDKER 557
REE + K+ + RE E K RE E++ RER+ +E++E +R ++ R
Sbjct: 548 REEEELQREKRRQEREREYREEEKLQREEDEKRRRQERERQYRELEE-----LRQEEQLR 602
Query: 558 DYHLKSEAEQLFKVLLTDLIKTSDDSWK--EVKRVLRKDARWSDISDKLERPLRD 716
D L+ E EQL + + ++ + K E +++LR++ + ++ + ER LR+
Sbjct: 603 DRKLREE-EQLLQEREEERLRRQERERKLREEEQLLRQEEQ--ELRQERERKLRE 654
Score = 30.4 bits (67), Expect = 5.3
Identities = 26/114 (22%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
Frame = +3
Query: 381 KREEWFKEFLKKNKTNSRENSETKRDRERKERQEASIREREKEVKESLSTAMRDRDKERD 560
+R+E ++ ++ + RE +++R+RK RE E+ ++ES +R +++ER
Sbjct: 1116 RRQERARKLREEEQLLRREEQLLRQERDRK------FREEEQLLQESEEERLRRQERERK 1169
Query: 561 YHLKSEAEQLFKVLLTDLIKTSDDSWK--EVKRVLRKDARWSDISDKLERPLRD 716
E EQL + + ++ + + K E +++LR++ + ++ + R LR+
Sbjct: 1170 LR---EEEQLLQEREEERLRRQERARKLREEEQLLRQEEQ--ELRQERARKLRE 1218
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,256,890
Number of Sequences: 369166
Number of extensions: 1134777
Number of successful extensions: 8166
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5778
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7106
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6776504000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)