Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_E06
(670 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P60842|IF4A1_HUMAN Eukaryotic initiation factor 4A-I (eI... 293 2e-79
sp|Q5R5F5|IF4A1_PONPY Eukaryotic initiation factor 4A-I (eI... 293 2e-79
sp|P29562|IF4A1_RABIT Eukaryotic initiation factor 4A-I (eI... 293 2e-79
sp|Q4R8K5|IF4A1_MACFA Eukaryotic initiation factor 4A-I (eI... 292 6e-79
sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A... 290 2e-78
sp|P10630|IF4A2_MOUSE Eukaryotic initiation factor 4A-II (e... 289 4e-78
sp|Q4R4Y9|IF4A2_MACFA Eukaryotic initiation factor 4A-II (e... 289 4e-78
sp|Q02748|IF4A_DROME Eukaryotic initiation factor 4A (eIF4A... 283 3e-76
sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A... 279 5e-75
sp|P10081|IF4A_YEAST Eukaryotic initiation factor 4A (eIF4A... 272 7e-73
>sp|P60842|IF4A1_HUMAN Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
sp|P60843|IF4A1_MOUSE Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 293 bits (751), Expect = 2e-79
Identities = 146/201 (72%), Positives = 171/201 (85%)
Frame = +3
Query: 6 DTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSEEDYKFETLTD 185
+TQ+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGIRQFY+NV E++K +TL D
Sbjct: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265
Query: 186 LYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRI 365
LYETLTITQAVIF NTRRKVD+LTE + A+ F VS+MHGDM Q RD IM+EFRSGSSR+
Sbjct: 266 LYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRV 325
Query: 366 LITTDLLARGIDVQQVSLVINYDLPSNRENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQ 545
LITTDLLARGIDVQQVSLVINYDLP+NRENYIH VAIN VT++D RTL+
Sbjct: 326 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLR 385
Query: 546 DLESYYSTHIEEMPMNIADLI 608
D+E++Y+T IEEMP+N+ADLI
Sbjct: 386 DIETFYNTSIEEMPLNVADLI 406
>sp|Q5R5F5|IF4A1_PONPY Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 293 bits (751), Expect = 2e-79
Identities = 146/201 (72%), Positives = 171/201 (85%)
Frame = +3
Query: 6 DTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSEEDYKFETLTD 185
+TQ+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGIRQFY+NV E++K +TL D
Sbjct: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265
Query: 186 LYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRI 365
LYETLTITQAVIF NTRRKVD+LTE + A+ F VS+MHGDM Q RD IM+EFRSGSSR+
Sbjct: 266 LYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRV 325
Query: 366 LITTDLLARGIDVQQVSLVINYDLPSNRENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQ 545
LITTDLLARGIDVQQVSLVINYDLP+NRENYIH VAIN VT++D RTL+
Sbjct: 326 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLR 385
Query: 546 DLESYYSTHIEEMPMNIADLI 608
D+E++Y+T IEEMP+N+ADLI
Sbjct: 386 DIETFYNTSIEEMPLNVADLI 406
>sp|P29562|IF4A1_RABIT Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 398
Score = 293 bits (751), Expect = 2e-79
Identities = 146/201 (72%), Positives = 171/201 (85%)
Frame = +3
Query: 6 DTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSEEDYKFETLTD 185
+TQ+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGIRQFY+NV E++K +TL D
Sbjct: 198 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 257
Query: 186 LYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRI 365
LYETLTITQAVIF NTRRKVD+LTE + A+ F VS+MHGDM Q RD IM+EFRSGSSR+
Sbjct: 258 LYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRV 317
Query: 366 LITTDLLARGIDVQQVSLVINYDLPSNRENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQ 545
LITTDLLARGIDVQQVSLVINYDLP+NRENYIH VAIN VT++D RTL+
Sbjct: 318 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLR 377
Query: 546 DLESYYSTHIEEMPMNIADLI 608
D+E++Y+T IEEMP+N+ADLI
Sbjct: 378 DIETFYNTSIEEMPLNVADLI 398
>sp|Q4R8K5|IF4A1_MACFA Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 292 bits (747), Expect = 6e-79
Identities = 145/201 (72%), Positives = 170/201 (84%)
Frame = +3
Query: 6 DTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSEEDYKFETLTD 185
+TQ+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGIRQFY+NV E++K +TL D
Sbjct: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265
Query: 186 LYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRI 365
LYETLTITQAVIF NTRRKVD+LTE + A+ F S+MHGDM Q RD IM+EFRSGSSR+
Sbjct: 266 LYETLTITQAVIFINTRRKVDWLTEKMHARDFTASAMHGDMDQKERDVIMREFRSGSSRV 325
Query: 366 LITTDLLARGIDVQQVSLVINYDLPSNRENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQ 545
LITTDLLARGIDVQQVSLVINYDLP+NRENYIH VAIN VT++D RTL+
Sbjct: 326 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLR 385
Query: 546 DLESYYSTHIEEMPMNIADLI 608
D+E++Y+T IEEMP+N+ADLI
Sbjct: 386 DIETFYNTSIEEMPLNVADLI 406
>sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 392
Score = 290 bits (742), Expect = 2e-78
Identities = 143/199 (71%), Positives = 167/199 (83%)
Frame = +3
Query: 12 QIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLY 191
Q+VLLSATMP DVLEVT KFMR P++ILVKK+ELTLEGI+QFYV V +E++K +TL DLY
Sbjct: 194 QVVLLSATMPQDVLEVTTKFMRDPIRILVKKDELTLEGIKQFYVAVEKEEWKLDTLCDLY 253
Query: 192 ETLTITQAVIFCNTRRKVDYLTESLKAKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILI 371
ET+T+TQAVIFCNTRRKVD+LTE L + F VSSMHGDM Q RD +M EFR+GSSRILI
Sbjct: 254 ETVTVTQAVIFCNTRRKVDWLTEQLTERDFTVSSMHGDMDQAQRDTLMHEFRTGSSRILI 313
Query: 372 TTDLLARGIDVQQVSLVINYDLPSNRENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDL 551
TTDLLARGIDVQQVSLVINYDLP+NRENYIH V+INFVT DD+R ++++
Sbjct: 314 TTDLLARGIDVQQVSLVINYDLPANRENYIHRIGRGGRFGRKGVSINFVTNDDVRMMREI 373
Query: 552 ESYYSTHIEEMPMNIADLI 608
E +Y+THIEEMPMNIADLI
Sbjct: 374 EQFYNTHIEEMPMNIADLI 392
>sp|P10630|IF4A2_MOUSE Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
sp|Q14240|IF4A2_HUMAN Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
sp|Q5R4X1|IF4A2_PONPY Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
Length = 407
Score = 289 bits (740), Expect = 4e-78
Identities = 143/199 (71%), Positives = 169/199 (84%)
Frame = +3
Query: 12 QIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLY 191
Q+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGI+QFY+NV E++K +TL DLY
Sbjct: 209 QVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLY 268
Query: 192 ETLTITQAVIFCNTRRKVDYLTESLKAKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILI 371
ETLTITQAVIF NTRRKVD+LTE + A+ F VS++HGDM Q RD IM+EFRSGSSR+LI
Sbjct: 269 ETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLI 328
Query: 372 TTDLLARGIDVQQVSLVINYDLPSNRENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDL 551
TTDLLARGIDVQQVSLVINYDLP+NRENYIH VAINFVT++D R L+D+
Sbjct: 329 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDI 388
Query: 552 ESYYSTHIEEMPMNIADLI 608
E++Y+T +EEMPMN+ADLI
Sbjct: 389 ETFYNTTVEEMPMNVADLI 407
>sp|Q4R4Y9|IF4A2_MACFA Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
Length = 408
Score = 289 bits (740), Expect = 4e-78
Identities = 143/199 (71%), Positives = 169/199 (84%)
Frame = +3
Query: 12 QIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSEEDYKFETLTDLY 191
Q+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGI+QFY+NV E++K +TL DLY
Sbjct: 210 QVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLY 269
Query: 192 ETLTITQAVIFCNTRRKVDYLTESLKAKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRILI 371
ETLTITQAVIF NTRRKVD+LTE + A+ F VS++HGDM Q RD IM+EFRSGSSR+LI
Sbjct: 270 ETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLI 329
Query: 372 TTDLLARGIDVQQVSLVINYDLPSNRENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQDL 551
TTDLLARGIDVQQVSLVINYDLP+NRENYIH VAINFVT++D R L+D+
Sbjct: 330 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDI 389
Query: 552 ESYYSTHIEEMPMNIADLI 608
E++Y+T +EEMPMN+ADLI
Sbjct: 390 ETFYNTTVEEMPMNVADLI 408
>sp|Q02748|IF4A_DROME Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 403
Score = 283 bits (724), Expect = 3e-76
Identities = 143/201 (71%), Positives = 164/201 (81%)
Frame = +3
Query: 6 DTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSEEDYKFETLTD 185
D Q++LLSATMPPDVLEV+R FMR PV ILVKKEELTLEGI+QFYVNV +E++K TL D
Sbjct: 203 DVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCD 262
Query: 186 LYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRI 365
LY+TL+ITQ+VIFCNTRRKVD LT+ + F VS+MHGDM+Q R+ IMK+FRSGSSR+
Sbjct: 263 LYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRV 322
Query: 366 LITTDLLARGIDVQQVSLVINYDLPSNRENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQ 545
LITTDLLARGIDVQQVSLVINYDLPSNRENYIH VAINF+T DD R L+
Sbjct: 323 LITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILK 382
Query: 546 DLESYYSTHIEEMPMNIADLI 608
D+E +Y T IEEMP NIADLI
Sbjct: 383 DIEQFYHTTIEEMPANIADLI 403
>sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 402
Score = 279 bits (713), Expect = 5e-75
Identities = 137/201 (68%), Positives = 165/201 (82%)
Frame = +3
Query: 6 DTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSEEDYKFETLTD 185
D Q+VLLSATMP +VL+VT +FMR+P++ILVKK+ELTLEGIRQFY+NV ++++KF+ L D
Sbjct: 202 DVQVVLLSATMPSEVLDVTNRFMRNPIRILVKKDELTLEGIRQFYINVQKDEWKFDCLCD 261
Query: 186 LYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRI 365
LY + +TQAVIFCNTRRKVD LTE + QF VS +HGDM Q RD IM+EFRSGSSR+
Sbjct: 262 LYNVVNVTQAVIFCNTRRKVDTLTEKMTENQFTVSCLHGDMDQAERDTIMREFRSGSSRV 321
Query: 366 LITTDLLARGIDVQQVSLVINYDLPSNRENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQ 545
LITTD+LARGIDVQQVSLVINYDLPSNRENYIH VAINFVT++D R L+
Sbjct: 322 LITTDILARGIDVQQVSLVINYDLPSNRENYIHRIGRSGRFGRKGVAINFVTENDARQLK 381
Query: 546 DLESYYSTHIEEMPMNIADLI 608
++ESYY+T IEEMP +IADLI
Sbjct: 382 EIESYYTTQIEEMPESIADLI 402
>sp|P10081|IF4A_YEAST Eukaryotic initiation factor 4A (eIF4A) (eIF-4A) (Stimulator factor
I 37 kDa component) (p37)
Length = 395
Score = 272 bits (695), Expect = 7e-73
Identities = 135/200 (67%), Positives = 166/200 (83%)
Frame = +3
Query: 9 TQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSEEDYKFETLTDL 188
TQ+VLLSATMP DVLEVT KFMR+PV+ILVKK+ELTLEGI+QFYVNV EE+YK+E LTDL
Sbjct: 195 TQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDL 254
Query: 189 YETLTITQAVIFCNTRRKVDYLTESLKAKQFIVSSMHGDMQQDMRDQIMKEFRSGSSRIL 368
Y+++++TQAVIFCNTRRKV+ LT L+ +F VS+++ D+ Q RD IMKEFRSGSSRIL
Sbjct: 255 YDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRIL 314
Query: 369 ITTDLLARGIDVQQVSLVINYDLPSNRENYIHXXXXXXXXXXXXVAINFVTQDDIRTLQD 548
I+TDLLARGIDVQQVSLVINYDLP+N+ENYIH VAINFVT +D+ +++
Sbjct: 315 ISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRE 374
Query: 549 LESYYSTHIEEMPMNIADLI 608
LE +YST IEE+P +IA L+
Sbjct: 375 LEKFYSTQIEELPSDIATLL 394
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,506,011
Number of Sequences: 369166
Number of extensions: 1178689
Number of successful extensions: 3194
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3038
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3099
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5657676120
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)