Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_D22
(821 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P70298|CUTL2_MOUSE Homeobox protein Cux-2 (Cut-like 2) 40 0.006
sp|O14529|CUTL2_HUMAN Homeobox protein Cux-2 (Cut-like 2) 39 0.013
sp|Q6KCD5|NPBL_MOUSE Nipped-B-like protein (Delangin homolo... 37 0.050
sp|Q9LD55|IF3A_ARATH Eukaryotic translation initiation fact... 36 0.11
sp|Q6KC79|NIPBL_HUMAN Nipped-B-like protein (Delangin) (SCC... 35 0.19
sp|P46939|UTRO_HUMAN Utrophin (Dystrophin-related protein 1... 35 0.25
sp|Q94738|HSP97_STRFN 97 kDa heat shock protein (Heat shock... 35 0.33
sp|P59565|DNAK_BUCBP Chaperone protein dnaK (Heat shock pro... 34 0.42
sp|O95613|PCNT_HUMAN Pericentrin (Pericentrin B) (Kendrin) 34 0.55
sp|P78621|SEPA_EMENI Cytokinesis protein sepA (FH1/2 protei... 33 0.72
>sp|P70298|CUTL2_MOUSE Homeobox protein Cux-2 (Cut-like 2)
Length = 1426
Score = 40.4 bits (93), Expect = 0.006
Identities = 46/151 (30%), Positives = 71/151 (47%), Gaps = 21/151 (13%)
Frame = +1
Query: 217 LRKKMQPDLSNHSINLGYIPAKLDSANSEVYRAELNKLRLAAQAKEKGGYAALRESNKQE 396
LR+K + ++ + +G I L+ AN RAE AAQ + +G L N
Sbjct: 161 LRRKYDEEAASKADEVGLIMTNLEKANQ---RAE------AAQREVEGLREQLASVNNS- 210
Query: 397 HIKNACTSPENES-------LSKKPIL-------DGEMLKLLSQGSSNR------KLVEM 516
I+ AC SP+ S L P L D E+L+LL R + V
Sbjct: 211 -IRLACCSPQGPSGEKVSFALCSGPRLEAALASKDREILRLLKDAQQLRHSLQELEEVSA 269
Query: 517 DKMAELDKKLD-RVEAIEKLETKLTSQHEQE 606
+++A+L+++L + EAIEKL+ KL +Q + E
Sbjct: 270 NQIADLERQLAAKSEAIEKLQEKLEAQADYE 300
>sp|O14529|CUTL2_HUMAN Homeobox protein Cux-2 (Cut-like 2)
Length = 1424
Score = 39.3 bits (90), Expect = 0.013
Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 21/151 (13%)
Frame = +1
Query: 217 LRKKMQPDLSNHSINLGYIPAKLDSANSEVYRAELNKLRLAAQAKEKGGYAALRESNKQE 396
LR+K + ++ + +G I L+ AN RAE AAQ + + L N
Sbjct: 162 LRRKYDEEAASKADEVGLIMTNLEKANQ---RAE------AAQREVESLREQLASVNSS- 211
Query: 397 HIKNACTSPE-------NESLSKKPIL-------DGEMLKLLSQ----GSSNRKLVEM-- 516
I+ AC SP+ N +L P L D E+L+LL SS ++L E
Sbjct: 212 -IRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDREILRLLKDVQHLQSSLQELEEASA 270
Query: 517 DKMAELDKKLD-RVEAIEKLETKLTSQHEQE 606
+++A+L+++L + EAIEKLE KL +Q + E
Sbjct: 271 NQIADLERQLTAKSEAIEKLEEKLQAQSDYE 301
>sp|Q6KCD5|NPBL_MOUSE Nipped-B-like protein (Delangin homolog) (SCC2 homolog)
Length = 2798
Score = 37.4 bits (85), Expect = 0.050
Identities = 41/154 (26%), Positives = 69/154 (44%), Gaps = 12/154 (7%)
Frame = +1
Query: 22 KIPKIGGGTSVSSDSDKSALLANLLKKPSSGSMN-LAKHIVEKSMGARQSIKPKPSNGNA 198
K+ K+G + D +K A +L+K S + L K EKS + +SIK KPS N
Sbjct: 979 KVEKMG----LVEDLNKGAKPVVVLQKLSLDDVQKLIKDREEKSRSSLKSIKNKPSKSNK 1034
Query: 199 GITFEGLRKKMQPDLSNHSINLGYIPAKLDSANSEVYRAELNKLRLAAQAKEKGGYAALR 378
G + + K++ P+L A+++S R ++NK R + EK YA +
Sbjct: 1035 GSIDQSVLKELPPELL----------AEIESTMPLCERVKMNK-RKRSTVNEKPKYAEIS 1083
Query: 379 -----------ESNKQEHIKNACTSPENESLSKK 447
ES+++ H K+ + E E ++
Sbjct: 1084 SDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRR 1117
>sp|Q9LD55|IF3A_ARATH Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta)
(Eukaryotic translation initiation factor 3 large
subunit) (eIF3a) (p114)
Length = 987
Score = 36.2 bits (82), Expect = 0.11
Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Frame = +1
Query: 316 ELNKLRLAAQAKEKGGYAALRESNKQEHIKNACTSPENESL----SKKPILDGEMLKLLS 483
E + RLAA+ E+ LRE ++E + E E KKP+LDGE K+
Sbjct: 602 EAEQKRLAAELAERRKQRILREIEEKELEEAQALLEETEKRMKKGKKKPLLDGE--KVTK 659
Query: 484 QGSSNRKLVE-MDKMAELDKKLDRV 555
Q R L E + + E++KKL ++
Sbjct: 660 QSVKERALTEQLKERQEMEKKLQKL 684
>sp|Q6KC79|NIPBL_HUMAN Nipped-B-like protein (Delangin) (SCC2 homolog)
Length = 2804
Score = 35.4 bits (80), Expect = 0.19
Identities = 40/154 (25%), Positives = 68/154 (44%), Gaps = 12/154 (7%)
Frame = +1
Query: 22 KIPKIGGGTSVSSDSDKSALLANLLKKPSSGSMN-LAKHIVEKSMGARQSIKPKPSNGNA 198
K+ KIG + D +K A +L+K S + L K +KS + + IK KPS N
Sbjct: 985 KVEKIG----LVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNK 1040
Query: 199 GITFEGLRKKMQPDLSNHSINLGYIPAKLDSANSEVYRAELNKLRLAAQAKEKGGYAALR 378
G + + K++ P+L A+++S R ++NK R + EK YA +
Sbjct: 1041 GSIDQSVLKELPPELL----------AEIESTMPLCERVKMNK-RKRSTVNEKPKYAEIS 1089
Query: 379 -----------ESNKQEHIKNACTSPENESLSKK 447
ES+++ H K+ + E E ++
Sbjct: 1090 SDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRR 1123
>sp|P46939|UTRO_HUMAN Utrophin (Dystrophin-related protein 1) (DRP1) (DRP)
Length = 3433
Score = 35.0 bits (79), Expect = 0.25
Identities = 28/126 (22%), Positives = 65/126 (51%), Gaps = 1/126 (0%)
Frame = +1
Query: 241 LSNHSINLGYIPAKLDSANSEVYRAELNKLRLAAQAKEKGGYAALRESNKQEHIKNACTS 420
L NH L + ++ +Y+AE L + ++K S ++E +K +
Sbjct: 1647 LMNHQNQLEIFDGNVAHISTWLYQAEA----LLDEIEKKP------TSKQEEIVKRLVSE 1696
Query: 421 PENESLSKKPILDGEMLKLLSQGSSNRKLVEMDKMAELDKKLDRV-EAIEKLETKLTSQH 597
++ +L + + D ++ + ++GSS+R+LVE K+AEL++ ++V + I+ + + +
Sbjct: 1697 LDDANLQVENVRDQALILMNARGSSSRELVE-PKLAELNRNFEKVSQHIKSAKLLIAQEP 1755
Query: 598 EQECIL 615
+C++
Sbjct: 1756 LYQCLV 1761
>sp|Q94738|HSP97_STRFN 97 kDa heat shock protein (Heat shock protein 110)
Length = 886
Score = 34.7 bits (78), Expect = 0.33
Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 15/92 (16%)
Frame = +1
Query: 430 ESLSKKPILDGEMLKLLSQGSSNRKLVEMDKMAELDKKLDRVEAIEKLETKLTSQ----- 594
E L K +L G+ L L SQG +E D+MA+++K L EA +T +Q
Sbjct: 734 EELGKALMLYGKTLDLYSQGDEKYSHIEKDEMAKVEKCLKEKEAWRDSKTSAQNQKAAYQ 793
Query: 595 ----------HEQECILFVCIQCQSKTAMKPR 660
E + + F+C +K KP+
Sbjct: 794 DPVVTAQQIRSEIQSMKFICDPIINKPKPKPK 825
>sp|P59565|DNAK_BUCBP Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa
protein) (HSP70)
Length = 638
Score = 34.3 bits (77), Expect = 0.42
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Frame = +1
Query: 211 EGLRKKMQPDLSNHSINL-GYIPAKLDSANSEVYRAELNKLRLAAQAKEKGGYAALRESN 387
+G RK+ + S NL G PA A EV + L AK+K +
Sbjct: 442 QGERKRSIDNKSLGQFNLDGIQPAPRGMAQIEVTFDIDSDGILHVSAKDKN-------TG 494
Query: 388 KQEHIKNACTSPENESLSKKPILDG-----------EMLKLLSQG-----SSNRKLVEMD 519
K++ I +S NE+ KK ILD E++K+ +QG S+ ++L +++
Sbjct: 495 KEQKITIKASSGLNETEIKKMILDAEQNSESDQKFEELVKVRNQGDQISHSTKKQLKDLE 554
Query: 520 KMAELDKKLDRVEAIEKLETKLTSQHE 600
K ++ + + EA+ KL+T L +++
Sbjct: 555 KTINVNDQKEINEALNKLDTALKGENK 581
>sp|O95613|PCNT_HUMAN Pericentrin (Pericentrin B) (Kendrin)
Length = 3336
Score = 33.9 bits (76), Expect = 0.55
Identities = 42/197 (21%), Positives = 82/197 (41%), Gaps = 12/197 (6%)
Frame = +1
Query: 52 VSSDSDKSALLANLLKKPSSGSMNLAKHIVEKSMGARQSIKPKPSNGNAGITFEGLRKKM 231
+ S+ +K+A + LK+ +L + K + A+ + E L+ +
Sbjct: 332 LQSEMEKNAQIVKTLKEDWESEKDLCLENLRKELSAKHQSE-----------MEDLQNQF 380
Query: 232 QPDLSNHSINLGYIPAKLDSANSEV------YRAELNKLRLAAQAKEKGGYAALR----- 378
Q +L+ L I + A + ++A + KLR Q++ L
Sbjct: 381 QKELAEQRAELEKIFQDKNQAERALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKE 440
Query: 379 -ESNKQEHIKNACTSPENESLSKKPILDGEMLKLLSQGSSNRKLVEMDKMAELDKKLDRV 555
E KQ ++N S E+ + + +L S +S ++L E+ + +L + RV
Sbjct: 441 SEKEKQLELENLQASYEDLKAQSQEEIRRLWSQLDSARTSRQELSELHE--QLLARTSRV 498
Query: 556 EAIEKLETKLTSQHEQE 606
E +E+L+ + +QHE E
Sbjct: 499 EDLEQLKQREKTQHESE 515
>sp|P78621|SEPA_EMENI Cytokinesis protein sepA (FH1/2 protein) (Forced expression
inhibition of growth A)
Length = 1790
Score = 33.5 bits (75), Expect = 0.72
Identities = 44/172 (25%), Positives = 75/172 (43%), Gaps = 14/172 (8%)
Frame = +1
Query: 127 AKHIVEKSMGARQSIKPKPSNGNAGITFEGLRKKMQPDLSNHSINLGYIPAKLDSANSEV 306
A+ I E ++ R +K + G +GL +K+Q + + G I +L S +E+
Sbjct: 736 ARQIAEAALAERDEMKAQVELGA-----DGLVRKLQKQIEEQT---GII--ELQSRQNEM 785
Query: 307 YRAELNKL-RLAAQAKEKGG------YAALRESN-------KQEHIKNACTSPENESLSK 444
+AEL + RL AQ ++ Y LR++ K+ ++ A T P +
Sbjct: 786 LKAELADVQRLRAQELQRNELETRELYLMLRDAQDIAASNAKKSNMGEAETDPAH----M 841
Query: 445 KPILDGEMLKLLSQGSSNRKLVEMDKMAELDKKLDRVEAIEKLETKLTSQHE 600
+ ILD E L + L+K+L+R + KLE K+ QH+
Sbjct: 842 RGILDREKL-----------------LTRLEKQLERTKTQFKLEGKVWGQHD 876
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.313 0.129 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,663,724
Number of Sequences: 369166
Number of extensions: 2181478
Number of successful extensions: 4414
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4273
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4411
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7907893860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)