Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_A20
(589 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O02649|CH60_DROME 60 kDa heat shock protein, mitochondri... 285 5e-77
sp|P18687|CH60_CRIGR 60 kDa heat shock protein, mitochondri... 283 2e-76
sp|P10809|CH60_HUMAN 60 kDa heat shock protein, mitochondri... 283 2e-76
sp|P63039|CH60_RAT 60 kDa heat shock protein, mitochondrial... 282 4e-76
sp|Q5NVM5|CH60_PONPY 60 kDa heat shock protein, mitochondri... 281 9e-76
sp|Q9VMN5|CH60C_DROME Probable 60 kDa heat shock protein ho... 272 5e-73
sp|P50140|CH60_CAEEL Chaperonin homolog HSP60, mitochondria... 266 3e-71
sp|P25420|CH63_HELVI 63 kDa chaperonin, mitochondrial precu... 237 2e-62
sp|O74261|HSP60_CANAL Heat shock protein 60, mitochondrial ... 228 9e-60
sp|P19882|HSP60_YEAST Heat shock protein 60, mitochondrial ... 223 2e-58
>sp|O02649|CH60_DROME 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
(Mitochondrial matrix protein P1)
Length = 573
Score = 285 bits (730), Expect = 5e-77
Identities = 137/196 (69%), Positives = 172/196 (87%)
Frame = +1
Query: 1 MKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPYFINTDKGAKCEFQDAFILFSEK 180
MKKVG+DG ITVKDGKTL DELEVIEGMKFDRGYISPYFIN+ KGAK EFQDA +L SEK
Sbjct: 186 MKKVGRDGVITVKDGKTLTDELEVIEGMKFDRGYISPYFINSSKGAKVEFQDALLLLSEK 245
Query: 181 KISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALVLNRLKLGLQVCAVKAPGFGDNR 360
KISS+QS+IP LE+ + Q+KPL+I+AED+DGEAL+ LV+NRLK+GLQV AVKAPGFGDNR
Sbjct: 246 KISSVQSIIPALELANAQRKPLVIIAEDIDGEALSTLVVNRLKIGLQVAAVKAPGFGDNR 305
Query: 361 KNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQEILITKDDTLVMKGKGLQKDIQK 540
K+TL DMA ++GGIVFGD+AD K+E+V++ DLG+ E++ITKDDTL++KGKG + D+ +
Sbjct: 306 KSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEVVITKDDTLLLKGKGKKDDVLR 365
Query: 541 RIDEIRDEIALSTSEY 588
R ++I+D+I +TSEY
Sbjct: 366 RANQIKDQIEDTTSEY 381
>sp|P18687|CH60_CRIGR 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
(Mitochondrial matrix protein P1)
Length = 573
Score = 283 bits (725), Expect = 2e-76
Identities = 133/196 (67%), Positives = 167/196 (85%)
Frame = +1
Query: 1 MKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPYFINTDKGAKCEFQDAFILFSEK 180
MKKVG+ G ITVKDGKTL+DELE+IEGMKFDRGYISPYFINT KG KCEFQDA++L SEK
Sbjct: 190 MKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEK 249
Query: 181 KISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALVLNRLKLGLQVCAVKAPGFGDNR 360
KISS+QS++P LE+ + +KPL+I+AEDVDGEAL+ LVLNRLK+GLQV AVKAPGFGDNR
Sbjct: 250 KISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNR 309
Query: 361 KNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQEILITKDDTLVMKGKGLQKDIQK 540
KN L+DMA +TGG VFG+E +E+VQ HDLG+ E+++TKDD +++KGKG + I+K
Sbjct: 310 KNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGEKAQIEK 369
Query: 541 RIDEIRDEIALSTSEY 588
RI EI +++ ++TSEY
Sbjct: 370 RIQEITEQLEITTSEY 385
>sp|P10809|CH60_HUMAN 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
(Mitochondrial matrix protein P1) (P60 lymphocyte
protein) (HuCHA60)
Length = 573
Score = 283 bits (724), Expect = 2e-76
Identities = 135/196 (68%), Positives = 168/196 (85%)
Frame = +1
Query: 1 MKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPYFINTDKGAKCEFQDAFILFSEK 180
MKKVG+ G ITVKDGKTL+DELE+IEGMKFDRGYISPYFINT KG KCEFQDA++L SEK
Sbjct: 190 MKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEK 249
Query: 181 KISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALVLNRLKLGLQVCAVKAPGFGDNR 360
KISSIQS++P LE+ + +KPL+I+AEDVDGEAL+ LVLNRLK+GLQV AVKAPGFGDNR
Sbjct: 250 KISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNR 309
Query: 361 KNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQEILITKDDTLVMKGKGLQKDIQK 540
KN L+DMA +TGG VFG+E T +E+VQ HDLG+ E+++TKDD +++KGKG + I+K
Sbjct: 310 KNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEK 369
Query: 541 RIDEIRDEIALSTSEY 588
RI EI +++ ++TSEY
Sbjct: 370 RIQEIIEQLDVTTSEY 385
>sp|P63039|CH60_RAT 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
(Mitochondrial matrix protein P1) (HSP-65)
sp|P63038|CH60_MOUSE 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
(Mitochondrial matrix protein P1) (HSP-65)
Length = 573
Score = 282 bits (722), Expect = 4e-76
Identities = 133/196 (67%), Positives = 167/196 (85%)
Frame = +1
Query: 1 MKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPYFINTDKGAKCEFQDAFILFSEK 180
MKKVG+ G ITVKDGKTL+DELE+IEGMKFDRGYISPYFINT KG KCEFQDA++L SEK
Sbjct: 190 MKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEK 249
Query: 181 KISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALVLNRLKLGLQVCAVKAPGFGDNR 360
KISS+QS++P LE+ + +KPL+I+AEDVDGEAL+ LVLNRLK+GLQV AVKAPGFGDNR
Sbjct: 250 KISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNR 309
Query: 361 KNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQEILITKDDTLVMKGKGLQKDIQK 540
KN L+DMA +TGG VFG+E +E+VQ HDLG+ E+++TKDD +++KGKG + I+K
Sbjct: 310 KNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGEVIVTKDDAMLLKGKGDKAHIEK 369
Query: 541 RIDEIRDEIALSTSEY 588
RI EI +++ ++TSEY
Sbjct: 370 RIQEITEQLDITTSEY 385
>sp|Q5NVM5|CH60_PONPY 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
Length = 573
Score = 281 bits (719), Expect = 9e-76
Identities = 133/196 (67%), Positives = 168/196 (85%)
Frame = +1
Query: 1 MKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPYFINTDKGAKCEFQDAFILFSEK 180
MKKVG+ G ITVKDGKTL+DELE+IEGMKFDRGYISPYFINT KG KCEFQDA++L SEK
Sbjct: 190 MKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEK 249
Query: 181 KISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALVLNRLKLGLQVCAVKAPGFGDNR 360
KISS+QS++P LE+ + +KPL+I+AEDVDGEAL+ LVLNRLK+GLQV AVKAPGFGDNR
Sbjct: 250 KISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNR 309
Query: 361 KNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQEILITKDDTLVMKGKGLQKDIQK 540
KN L+DMA +TGG VFG+E T +E+VQ HDLG+ E+++TKDD ++++GKG + I+K
Sbjct: 310 KNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLEGKGDKAQIEK 369
Query: 541 RIDEIRDEIALSTSEY 588
RI EI +++ ++TSEY
Sbjct: 370 RIQEIIEQLDVTTSEY 385
>sp|Q9VMN5|CH60C_DROME Probable 60 kDa heat shock protein homolog 2, mitochondrial
precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat
shock protein 60) (HSP-60)
Length = 576
Score = 272 bits (695), Expect = 5e-73
Identities = 127/196 (64%), Positives = 165/196 (84%)
Frame = +1
Query: 1 MKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPYFINTDKGAKCEFQDAFILFSEK 180
+KKVG+DG ITVKDGKTL DELEVIEGMKFDRGYISPYFINT KGAK EFQDA +LF EK
Sbjct: 190 IKKVGRDGVITVKDGKTLCDELEVIEGMKFDRGYISPYFINTSKGAKVEFQDALLLFCEK 249
Query: 181 KISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALVLNRLKLGLQVCAVKAPGFGDNR 360
KI S S++P LE+ + Q+KPL+I+AED++ EAL+ LV+NRLK+GLQVCAVKAPGFGDNR
Sbjct: 250 KIKSAPSIVPALELANAQRKPLVIIAEDLEAEALSTLVVNRLKVGLQVCAVKAPGFGDNR 309
Query: 361 KNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQEILITKDDTLVMKGKGLQKDIQK 540
K L DMA +TGGIVFGDEA+ ++E++++ D GR E++++KDDT+++KGKG + +++K
Sbjct: 310 KENLMDMAVATGGIVFGDEANMVRLEDIKMSDFGRVGEVVVSKDDTMLLKGKGQKAEVEK 369
Query: 541 RIDEIRDEIALSTSEY 588
R++ +R+ I STS Y
Sbjct: 370 RVEGLREAIKESTSSY 385
>sp|P50140|CH60_CAEEL Chaperonin homolog HSP60, mitochondrial precursor (Heat shock
protein 60) (HSP-60)
Length = 568
Score = 266 bits (680), Expect = 3e-71
Identities = 126/196 (64%), Positives = 162/196 (82%)
Frame = +1
Query: 1 MKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPYFINTDKGAKCEFQDAFILFSEK 180
MKKVG G ITVKDGKTL+DELE+IEGMKFDRGYISPYFI + KGAK E++ A +L SEK
Sbjct: 181 MKKVGTTGVITVKDGKTLNDELELIEGMKFDRGYISPYFITSAKGAKVEYEKALVLLSEK 240
Query: 181 KISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALVLNRLKLGLQVCAVKAPGFGDNR 360
KIS +Q ++P LE+ ++ ++PL+I+AEDVDGEALT LVLNRLK+GLQV A+KAPGFGDNR
Sbjct: 241 KISQVQDIVPALELANKLRRPLVIIAEDVDGEALTTLVLNRLKVGLQVVAIKAPGFGDNR 300
Query: 361 KNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQEILITKDDTLVMKGKGLQKDIQK 540
KNTL+DM +TG +FGD+++ KIE++ +DLG E+ ITKDDTL+++G+G Q +I+K
Sbjct: 301 KNTLKDMGIATGATIFGDDSNLIKIEDITANDLGEVDEVTITKDDTLLLRGRGDQTEIEK 360
Query: 541 RIDEIRDEIALSTSEY 588
RI+ I DEI STS+Y
Sbjct: 361 RIEHITDEIEQSTSDY 376
>sp|P25420|CH63_HELVI 63 kDa chaperonin, mitochondrial precursor (p63)
Length = 569
Score = 237 bits (604), Expect = 2e-62
Identities = 113/196 (57%), Positives = 152/196 (77%)
Frame = +1
Query: 1 MKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPYFINTDKGAKCEFQDAFILFSEK 180
M +VGK+G ITVKDGKTL DELE+IEGMKFDRGY+SPYFIN++KG K E+ DA +L+SEK
Sbjct: 193 MNRVGKNGVITVKDGKTLEDELEIIEGMKFDRGYVSPYFINSNKGPKVEYNDALVLYSEK 252
Query: 181 KISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALVLNRLKLGLQVCAVKAPGFGDNR 360
KI ++P LE+ + QKKPL+I+AED DGE L+ LV+N+LK+GL V AVKAPGFG+ R
Sbjct: 253 KIYYASQVVPALELANSQKKPLVIIAEDYDGEPLSVLVVNKLKIGLPVVAVKAPGFGEYR 312
Query: 361 KNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQEILITKDDTLVMKGKGLQKDIQK 540
N L DMA +TGG VF D+ + ++E+ Q G+ E++ITKD TL++KGKG +I++
Sbjct: 313 TNALLDMAAATGG-VFEDDTNLVRLEDCQAESFGQVGEVIITKDSTLLLKGKGDPNEIKQ 371
Query: 541 RIDEIRDEIALSTSEY 588
RID+I++E+ +TS Y
Sbjct: 372 RIDQIKEELETATSNY 387
>sp|O74261|HSP60_CANAL Heat shock protein 60, mitochondrial precursor (60 kDa chaperonin)
(Protein Cpn60)
Length = 566
Score = 228 bits (581), Expect = 9e-60
Identities = 116/197 (58%), Positives = 152/197 (77%), Gaps = 1/197 (0%)
Frame = +1
Query: 1 MKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPYFINTDKGAKCEFQDAFILFSEK 180
M+KVGK+G ITVK+GKTL DELEV EGMKFDRG+ISPYFI K K EF++ IL SEK
Sbjct: 182 MEKVGKEGVITVKEGKTLEDELEVTEGMKFDRGFISPYFITNTKTGKVEFENPLILLSEK 241
Query: 181 KISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALVLNRLKLGLQVCAVKAPGFGDNR 360
KISSIQ ++P LE+++Q ++PLLI+AEDVDGEAL A +LN+L+ +QVCAVKAPGFGDNR
Sbjct: 242 KISSIQDILPSLELSNQTRRPLLIIAEDVDGEALAACILNKLRGQVQVCAVKAPGFGDNR 301
Query: 361 KNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQEILITKDDTLVMKGKGLQKDIQK 540
KNTL D+A +GG VF +E D K EN + LG A + ITK+DT+++ G+G + +++
Sbjct: 302 KNTLGDIAILSGGTVFTEELD-IKPENATIEQLGSAGAVTITKEDTVLLNGEGSKDNLEA 360
Query: 541 RIDEIRDEIA-LSTSEY 588
R ++IR IA + T+EY
Sbjct: 361 RCEQIRSVIADVHTTEY 377
>sp|P19882|HSP60_YEAST Heat shock protein 60, mitochondrial precursor (Stimulator factor I
66 kDa component) (P66) (CPN60)
Length = 572
Score = 223 bits (569), Expect = 2e-58
Identities = 107/194 (55%), Positives = 150/194 (77%)
Frame = +1
Query: 1 MKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPYFINTDKGAKCEFQDAFILFSEK 180
M+KVGK+G IT+++G+TL DELEV EGM+FDRG+ISPYFI K +K EF+ +L SEK
Sbjct: 187 MEKVGKEGVITIREGRTLEDELEVTEGMRFDRGFISPYFITDPKSSKVEFEKPLLLLSEK 246
Query: 181 KISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALVLNRLKLGLQVCAVKAPGFGDNR 360
KISSIQ ++P LE+++Q ++PLLI+AEDVDGEAL A +LN+L+ ++VCAVKAPGFGDNR
Sbjct: 247 KISSIQDILPALEISNQSRRPLLIIAEDVDGEALAACILNKLRGQVKVCAVKAPGFGDNR 306
Query: 361 KNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQEILITKDDTLVMKGKGLQKDIQK 540
KNT+ D+A TGG VF +E D K E + +LG I +TK+DT+++ G G ++ IQ+
Sbjct: 307 KNTIGDIAVLTGGTVFTEELD-LKPEQCTIENLGSCDSITVTKEDTVILNGSGPKEAIQE 365
Query: 541 RIDEIRDEIALSTS 582
RI++I+ I ++T+
Sbjct: 366 RIEQIKGSIDITTT 379
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.317 0.137 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,222,880
Number of Sequences: 369166
Number of extensions: 1234027
Number of successful extensions: 4379
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3992
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4092
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4406202450
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)