Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_O09
(785 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P42357|HUTH_HUMAN Histidine ammonia-lyase (Histidase) 164 2e-40
sp|P35492|HUTH_MOUSE Histidine ammonia-lyase (Histidase) 162 7e-40
sp|P21213|HUTH_RAT Histidine ammonia-lyase (Histidase) 162 1e-39
sp|Q20502|HUTH_CAEEL Probable histidine ammonia-lyase (Hist... 141 2e-33
sp|Q67JH4|HUTH_SYMTH Histidine ammonia-lyase (Histidase) 115 1e-25
sp|Q6AKP3|HUTH_DESPS Histidine ammonia-lyase (Histidase) 115 2e-25
sp|Q5WWW8|HUTH_LEGPL Histidine ammonia-lyase (Histidase) 113 5e-25
sp|Q5X5I5|HUTH_LEGPA Histidine ammonia-lyase (Histidase) 113 5e-25
sp|Q5ZVR0|HUTH_LEGPH Histidine ammonia-lyase (Histidase) 113 5e-25
sp|Q5NZX8|HUTH_AZOSE Histidine ammonia-lyase (Histidase) 113 7e-25
>sp|P42357|HUTH_HUMAN Histidine ammonia-lyase (Histidase)
Length = 657
Score = 164 bits (416), Expect = 2e-40
Identities = 85/140 (60%), Positives = 102/140 (72%)
Frame = +1
Query: 1 AAALVSENKVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQ 180
AAALVSENK L HPSSVDSL+TSA EDHVSMG +AARKAL V+ +VE VLAIELLA+ Q
Sbjct: 503 AAALVSENKALCHPSSVDSLSTSAATEDHVSMGGWAARKALRVIEHVEQVLAIELLAACQ 562
Query: 181 ALEFLRPLKSTEPLEAVVRLIRTTVKPWDKDRFMAPDIEHVVNTLKAGEIWNVVEPFIEN 360
+EFLRPLK+T PLE V L+R+ V+PW KDRFMAPDIE L ++W V P+IE
Sbjct: 563 GIEFLRPLKTTTPLEKVYDLVRSVVRPWIKDRFMAPDIEAAHRLLLEQKVWEVAAPYIEK 622
Query: 361 FESYKLPDLWISSPTTTSLK 420
+ +P+ SPT SL+
Sbjct: 623 YRMEHIPESRPLSPTAFSLQ 642
>sp|P35492|HUTH_MOUSE Histidine ammonia-lyase (Histidase)
Length = 657
Score = 162 bits (411), Expect = 7e-40
Identities = 85/140 (60%), Positives = 102/140 (72%)
Frame = +1
Query: 1 AAALVSENKVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQ 180
AAALVSE+K L HPSSVDSL+TSA EDHVSMG +AARKAL VV +VE VLAIELLA+ Q
Sbjct: 503 AAALVSESKALCHPSSVDSLSTSAATEDHVSMGGWAARKALRVVEHVEQVLAIELLAACQ 562
Query: 181 ALEFLRPLKSTEPLEAVVRLIRTTVKPWDKDRFMAPDIEHVVNTLKAGEIWNVVEPFIEN 360
+EFLRPLK+T PLE V L+R+ V+PW KDRFMAPDIE L ++W V P+IE
Sbjct: 563 GIEFLRPLKTTTPLEKVYDLVRSVVRPWIKDRFMAPDIEAAHRLLLDQKVWEVAAPYIEK 622
Query: 361 FESYKLPDLWISSPTTTSLK 420
+ +P+ SPT SL+
Sbjct: 623 YRMEHIPESRPLSPTAFSLE 642
>sp|P21213|HUTH_RAT Histidine ammonia-lyase (Histidase)
Length = 657
Score = 162 bits (410), Expect = 1e-39
Identities = 84/140 (60%), Positives = 102/140 (72%)
Frame = +1
Query: 1 AAALVSENKVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQ 180
AAALVSE+K L HPSSVDSL+TSA EDHVSMG +AARKAL V+ +VE VLAIELLA+ Q
Sbjct: 503 AAALVSESKALCHPSSVDSLSTSAATEDHVSMGGWAARKALRVIEHVEQVLAIELLAACQ 562
Query: 181 ALEFLRPLKSTEPLEAVVRLIRTTVKPWDKDRFMAPDIEHVVNTLKAGEIWNVVEPFIEN 360
+EFLRPLK+T PLE V L+R+ V+PW KDRFMAPDIE L ++W V P+IE
Sbjct: 563 GIEFLRPLKTTTPLEKVYDLVRSVVRPWIKDRFMAPDIEAAHRLLLDQKVWEVAAPYIEK 622
Query: 361 FESYKLPDLWISSPTTTSLK 420
+ +P+ SPT SL+
Sbjct: 623 YRMEHIPESRPLSPTAFSLE 642
>sp|Q20502|HUTH_CAEEL Probable histidine ammonia-lyase (Histidase)
Length = 677
Score = 141 bits (356), Expect = 2e-33
Identities = 70/123 (56%), Positives = 91/123 (73%)
Frame = +1
Query: 1 AAALVSENKVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQ 180
AA+LVSENKVL HPSSVDS+ TS QEDHVSMG FAARKAL VV +VE VLA+ELLA+ Q
Sbjct: 519 AASLVSENKVLCHPSSVDSIPTSCNQEDHVSMGGFAARKALTVVEHVEAVLAMELLAACQ 578
Query: 181 ALEFLRPLKSTEPLEAVVRLIRTTVKPWDKDRFMAPDIEHVVNTLKAGEIWNVVEPFIEN 360
+EFL+PL ST PL + +L+R+ P ++DR+M P+I+ V+ ++ IW V P +E
Sbjct: 579 GIEFLKPLISTAPLHKIYQLVRSVAPPLNEDRYMKPEIDAVLEMIRENRIWEAVLPHLET 638
Query: 361 FES 369
E+
Sbjct: 639 LEA 641
>sp|Q67JH4|HUTH_SYMTH Histidine ammonia-lyase (Histidase)
Length = 507
Score = 115 bits (289), Expect = 1e-25
Identities = 63/115 (54%), Positives = 77/115 (66%)
Frame = +1
Query: 1 AAALVSENKVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQ 180
AA+LVSENKVL HP+SVDS+ +SA QEDHVSMG AARKA +V++NV VLAIELL + Q
Sbjct: 386 AASLVSENKVLAHPASVDSIPSSANQEDHVSMGTTAARKARQVIANVRRVLAIELLCAAQ 445
Query: 181 ALEFLRPLKSTEPLEAVVRLIRTTVKPWDKDRFMAPDIEHVVNTLKAGEIWNVVE 345
ALEF+ P + A IR V P DR +APDIE + + GE+ VE
Sbjct: 446 ALEFVGPERLAPATRAAYAAIRERVAPLSGDRVLAPDIEALAELVHNGELVAAVE 500
>sp|Q6AKP3|HUTH_DESPS Histidine ammonia-lyase (Histidase)
Length = 512
Score = 115 bits (287), Expect = 2e-25
Identities = 59/114 (51%), Positives = 80/114 (70%)
Frame = +1
Query: 1 AAALVSENKVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQ 180
AAAL SENK L HP+SVDSL TSA QEDHVSM FAAR+ LE+ N +LAIELLA+ Q
Sbjct: 389 AAALASENKSLAHPASVDSLPTSANQEDHVSMATFAARRLLEMADNTAGILAIELLAACQ 448
Query: 181 ALEFLRPLKSTEPLEAVVRLIRTTVKPWDKDRFMAPDIEHVVNTLKAGEIWNVV 342
++F PLK++ LE ++R V +D+DR++APDI++ ++AG ++V
Sbjct: 449 GIDFRAPLKTSPLLEEAKSIVRQVVAFYDQDRYLAPDIKNAQALVQAGAFNHLV 502
>sp|Q5WWW8|HUTH_LEGPL Histidine ammonia-lyase (Histidase)
Length = 506
Score = 113 bits (283), Expect = 5e-25
Identities = 55/101 (54%), Positives = 73/101 (72%)
Frame = +1
Query: 1 AAALVSENKVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQ 180
AA+ S+NK L HP SVDSL TSA QEDHVSM AAR+ E++ N +LAIELLA+ Q
Sbjct: 389 AASCASDNKALAHPHSVDSLPTSANQEDHVSMATSAARRLHEMIDNTSTILAIELLAACQ 448
Query: 181 ALEFLRPLKSTEPLEAVVRLIRTTVKPWDKDRFMAPDIEHV 303
LEF +PLK++ L+ + + +R+ VK +DKDR+ APDIE +
Sbjct: 449 GLEFHKPLKTSPQLDKIYQSVRSVVKEYDKDRYFAPDIEKI 489
>sp|Q5X5I5|HUTH_LEGPA Histidine ammonia-lyase (Histidase)
Length = 506
Score = 113 bits (283), Expect = 5e-25
Identities = 55/101 (54%), Positives = 73/101 (72%)
Frame = +1
Query: 1 AAALVSENKVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQ 180
AA+ S+NK L HP SVDSL TSA QEDHVSM AAR+ E++ N +LAIELLA+ Q
Sbjct: 389 AASCASDNKALAHPHSVDSLPTSANQEDHVSMATSAARRLHEMIDNTSTILAIELLAACQ 448
Query: 181 ALEFLRPLKSTEPLEAVVRLIRTTVKPWDKDRFMAPDIEHV 303
LEF +PLK++ L+ + + +R+ VK +DKDR+ APDIE +
Sbjct: 449 GLEFHKPLKTSPQLDKIYQSVRSVVKEYDKDRYFAPDIEKI 489
>sp|Q5ZVR0|HUTH_LEGPH Histidine ammonia-lyase (Histidase)
Length = 506
Score = 113 bits (283), Expect = 5e-25
Identities = 55/101 (54%), Positives = 73/101 (72%)
Frame = +1
Query: 1 AAALVSENKVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQ 180
AA+ S+NK L HP SVDSL TSA QEDHVSM AAR+ E++ N +LAIELLA+ Q
Sbjct: 389 AASCASDNKALAHPHSVDSLPTSANQEDHVSMATSAARRLHEMIDNTSTILAIELLAACQ 448
Query: 181 ALEFLRPLKSTEPLEAVVRLIRTTVKPWDKDRFMAPDIEHV 303
LEF +PLK++ L+ + + +R+ VK +DKDR+ APDIE +
Sbjct: 449 GLEFHKPLKTSPQLDKIYQSVRSVVKEYDKDRYFAPDIEKI 489
>sp|Q5NZX8|HUTH_AZOSE Histidine ammonia-lyase (Histidase)
Length = 526
Score = 113 bits (282), Expect = 7e-25
Identities = 59/108 (54%), Positives = 76/108 (70%)
Frame = +1
Query: 1 AAALVSENKVLTHPSSVDSLTTSAGQEDHVSMGAFAARKALEVVSNVENVLAIELLASVQ 180
AAAL SENK+L HP+SVDSL TSA QEDHVSM FAARK E+ N +LAIELLA+ Q
Sbjct: 388 AAALASENKLLAHPASVDSLPTSANQEDHVSMSTFAARKLGELADNTATILAIELLAAAQ 447
Query: 181 ALEFLRPLKSTEPLEAVVRLIRTTVKPWDKDRFMAPDIEHVVNTLKAG 324
+E P +++ L+AV+ LIR+ V +D DR+ APDI + + + AG
Sbjct: 448 GVELRAPHRTSPRLQAVLALIRSRVPHYDIDRYFAPDIASIKDEVSAG 495
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,590,373
Number of Sequences: 369166
Number of extensions: 1344984
Number of successful extensions: 3746
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3640
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3737
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7405750800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)