Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_N19
(297 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O35737|HNRH1_MOUSE Heterogeneous nuclear ribonucleoprote... 93 2e-19
sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprote... 93 2e-19
sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprote... 92 4e-19
sp|P70333|HNRH2_MOUSE Heterogeneous nuclear ribonucleoprote... 92 4e-19
sp|P52597|HNRPF_HUMAN Heterogeneous nuclear ribonucleoprote... 92 5e-19
sp|Q60HC3|HNRPF_MACFA Heterogeneous nuclear ribonucleoprote... 92 5e-19
sp|P31942|HNRH3_HUMAN Heterogeneous nuclear ribonucleoprote... 84 8e-17
sp|Q8C5Q4|GRSF1_MOUSE G-rich sequence factor 1 (GRSF-1) 74 8e-14
sp|Q12849|GRSF1_HUMAN G-rich sequence factor 1 (GRSF-1) 74 8e-14
sp|Q8R3C6|RBM19_MOUSE Probable RNA-binding protein 19 (RNA-... 59 3e-09
>sp|O35737|HNRH1_MOUSE Heterogeneous nuclear ribonucleoprotein H (hnRNP H)
Length = 449
Score = 92.8 bits (229), Expect = 2e-19
Identities = 41/75 (54%), Positives = 54/75 (72%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDGKNTGEAEADFYSETDAVKAMEKDRC 117
+HMRGLPY ATE D++ FF+PL V I++GPDG+ TGEA+ +F + DAV AM KD+
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKA 350
Query: 116 KMSWRYIELFRGSSA 72
M RY+ELF S+A
Sbjct: 351 NMQHRYVELFLNSTA 365
Score = 55.5 bits (132), Expect = 4e-08
Identities = 28/77 (36%), Positives = 49/77 (63%), Gaps = 2/77 (2%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPD--GKNTGEAEADFYSETDAVKAMEKD 123
+ +RGLP+ +++++ +FF+ L + I L D G++TGEA F S+ A KA++K
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 122 RCKMSWRYIELFRGSSA 72
+ ++ RYIE+F+ S A
Sbjct: 173 KERIGHRYIEIFKSSRA 189
Score = 47.8 bits (112), Expect = 8e-06
Identities = 23/78 (29%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAE----VKIQLGPDGKNTGEAEADFYSETDAVKAME 129
+ +RGLP+S + +V FF+ ++ ++ +G+ +GEA + SE + A++
Sbjct: 13 VKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALK 72
Query: 128 KDRCKMSWRYIELFRGSS 75
KDR M RY+E+F+ ++
Sbjct: 73 KDRETMGHRYVEVFKSNN 90
>sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprotein H (hnRNP H)
Length = 449
Score = 92.8 bits (229), Expect = 2e-19
Identities = 41/75 (54%), Positives = 54/75 (72%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDGKNTGEAEADFYSETDAVKAMEKDRC 117
+HMRGLPY ATE D++ FF+PL V I++GPDG+ TGEA+ +F + DAV AM KD+
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKA 350
Query: 116 KMSWRYIELFRGSSA 72
M RY+ELF S+A
Sbjct: 351 NMQHRYVELFLNSTA 365
Score = 55.5 bits (132), Expect = 4e-08
Identities = 28/77 (36%), Positives = 49/77 (63%), Gaps = 2/77 (2%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPD--GKNTGEAEADFYSETDAVKAMEKD 123
+ +RGLP+ +++++ +FF+ L + I L D G++TGEA F S+ A KA++K
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 122 RCKMSWRYIELFRGSSA 72
+ ++ RYIE+F+ S A
Sbjct: 173 KERIGHRYIEIFKSSRA 189
Score = 47.8 bits (112), Expect = 8e-06
Identities = 23/78 (29%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAE----VKIQLGPDGKNTGEAEADFYSETDAVKAME 129
+ +RGLP+S + +V FF+ ++ ++ +G+ +GEA + SE + A++
Sbjct: 13 VKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALK 72
Query: 128 KDRCKMSWRYIELFRGSS 75
KDR M RY+E+F+ ++
Sbjct: 73 KDRETMGHRYVEVFKSNN 90
>sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprotein H' (hnRNP H') (FTP-3)
Length = 449
Score = 92.0 bits (227), Expect = 4e-19
Identities = 41/75 (54%), Positives = 54/75 (72%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDGKNTGEAEADFYSETDAVKAMEKDRC 117
+HMRGLPY ATE D++ FF+PL V I++GPDG+ TGEA+ +F + DAV AM KD+
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKA 350
Query: 116 KMSWRYIELFRGSSA 72
M RY+ELF S+A
Sbjct: 351 NMQHRYVELFLNSTA 365
Score = 54.3 bits (129), Expect = 8e-08
Identities = 27/77 (35%), Positives = 49/77 (63%), Gaps = 2/77 (2%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPD--GKNTGEAEADFYSETDAVKAMEKD 123
+ +RGLP+ +++++ +FF+ L + + L D G++TGEA F S+ A KA++K
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 122 RCKMSWRYIELFRGSSA 72
+ ++ RYIE+F+ S A
Sbjct: 173 KERIGHRYIEIFKSSRA 189
Score = 48.1 bits (113), Expect = 6e-06
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAE----VKIQLGPDGKNTGEAEADFYSETDAVKAME 129
+ +RGLP+S + +V FF+ ++ ++ +G+ +GEA + SE + A++
Sbjct: 13 VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72
Query: 128 KDRCKMSWRYIELFRGSS 75
KDR M RY+E+F+ +S
Sbjct: 73 KDRETMGHRYVEVFKSNS 90
>sp|P70333|HNRH2_MOUSE Heterogeneous nuclear ribonucleoprotein H' (hnRNP H')
Length = 449
Score = 92.0 bits (227), Expect = 4e-19
Identities = 41/75 (54%), Positives = 54/75 (72%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDGKNTGEAEADFYSETDAVKAMEKDRC 117
+HMRGLPY ATE D++ FF+PL V I++GPDG+ TGEA+ +F + DAV AM KD+
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKA 350
Query: 116 KMSWRYIELFRGSSA 72
M RY+ELF S+A
Sbjct: 351 NMQHRYVELFLNSTA 365
Score = 54.3 bits (129), Expect = 8e-08
Identities = 27/77 (35%), Positives = 49/77 (63%), Gaps = 2/77 (2%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPD--GKNTGEAEADFYSETDAVKAMEKD 123
+ +RGLP+ +++++ +FF+ L + + L D G++TGEA F S+ A KA++K
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 122 RCKMSWRYIELFRGSSA 72
+ ++ RYIE+F+ S A
Sbjct: 173 KERIGHRYIEIFKSSRA 189
Score = 49.3 bits (116), Expect = 3e-06
Identities = 25/78 (32%), Positives = 46/78 (58%), Gaps = 4/78 (5%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAE----VKIQLGPDGKNTGEAEADFYSETDAVKAME 129
+ +RGLP+S + ++V FF+ ++ V+ +G+ +GEA + SE + A++
Sbjct: 13 VKVRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTREGRPSGEAFVELESEDEVKLALK 72
Query: 128 KDRCKMSWRYIELFRGSS 75
KDR M RY+E+F+ +S
Sbjct: 73 KDRETMGHRYVEVFKSNS 90
>sp|P52597|HNRPF_HUMAN Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like
protein mcs94-1)
Length = 415
Score = 91.7 bits (226), Expect = 5e-19
Identities = 41/74 (55%), Positives = 53/74 (71%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDGKNTGEAEADFYSETDAVKAMEKDRC 117
+HMRGLPY ATE D++ FF+PL V I++GPDG+ TGEA+ +F + +AV AM KDR
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA 350
Query: 116 KMSWRYIELFRGSS 75
M RYIELF S+
Sbjct: 351 NMQHRYIELFLNST 364
Score = 56.6 bits (135), Expect = 2e-08
Identities = 27/75 (36%), Positives = 48/75 (64%), Gaps = 2/75 (2%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAE--VKIQLGPDGKNTGEAEADFYSETDAVKAMEKD 123
+ +RGLP+ T++++ +FF+ L + + + + P+GK TGEA F S+ A KA+ K
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 122 RCKMSWRYIELFRGS 78
+ ++ RYIE+F+ S
Sbjct: 173 KERIGHRYIEVFKSS 187
Score = 49.3 bits (116), Expect = 3e-06
Identities = 27/75 (36%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRV----AEVKIQLGPDGKNTGEAEADFYSETDAVKAME 129
+ +RGLP+S + +DV F + + A V +G+ +GEA + SE D A++
Sbjct: 13 VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72
Query: 128 KDRCKMSWRYIELFR 84
KDR M RYIE+F+
Sbjct: 73 KDRESMGHRYIEVFK 87
>sp|Q60HC3|HNRPF_MACFA Heterogeneous nuclear ribonucleoprotein F (hnRNP F)
Length = 415
Score = 91.7 bits (226), Expect = 5e-19
Identities = 41/74 (55%), Positives = 53/74 (71%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDGKNTGEAEADFYSETDAVKAMEKDRC 117
+HMRGLPY ATE D++ FF+PL V I++GPDG+ TGEA+ +F + +AV AM KDR
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA 350
Query: 116 KMSWRYIELFRGSS 75
M RYIELF S+
Sbjct: 351 NMQHRYIELFLNST 364
Score = 56.6 bits (135), Expect = 2e-08
Identities = 27/75 (36%), Positives = 48/75 (64%), Gaps = 2/75 (2%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAE--VKIQLGPDGKNTGEAEADFYSETDAVKAMEKD 123
+ +RGLP+ T++++ +FF+ L + + + + P+GK TGEA F S+ A KA+ K
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 122 RCKMSWRYIELFRGS 78
+ ++ RYIE+F+ S
Sbjct: 173 KERIGHRYIEVFKSS 187
Score = 49.3 bits (116), Expect = 3e-06
Identities = 27/75 (36%), Positives = 42/75 (56%), Gaps = 4/75 (5%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRV----AEVKIQLGPDGKNTGEAEADFYSETDAVKAME 129
+ +RGLP+S + +DV F + + A V +G+ +GEA + SE D A++
Sbjct: 13 VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72
Query: 128 KDRCKMSWRYIELFR 84
KDR M RYIE+F+
Sbjct: 73 KDRESMGHRYIEVFK 87
>sp|P31942|HNRH3_HUMAN Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (hnRNP 2H9)
Length = 346
Score = 84.3 bits (207), Expect = 8e-17
Identities = 40/77 (51%), Positives = 51/77 (66%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDGKNTGEAEADFYSETDAVKAMEKDRC 117
+HMRGLP+ ATE D+ FF+PL V I +G DG+ TGEA+ +F + DAV AM KD+
Sbjct: 197 VHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKN 256
Query: 116 KMSWRYIELFRGSSALG 66
M RYIELF S+ G
Sbjct: 257 NMQHRYIELFLNSTPGG 273
Score = 51.2 bits (121), Expect = 7e-07
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 2/75 (2%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPD--GKNTGEAEADFYSETDAVKAMEKD 123
+ +RGLP+ +++++ +FF L + I L D G++TGEA F S+ A A+ K
Sbjct: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
Query: 122 RCKMSWRYIELFRGS 78
+ ++ RYIE+FR S
Sbjct: 78 KERIGHRYIEIFRSS 92
>sp|Q8C5Q4|GRSF1_MOUSE G-rich sequence factor 1 (GRSF-1)
Length = 479
Score = 74.3 bits (181), Expect = 8e-14
Identities = 36/77 (46%), Positives = 47/77 (61%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDGKNTGEAEADFYSETDAVKAMEKDRC 117
+HMRGLP+ A +D+ FFAPL+ + ++ GK TGEA+ F + DAV AM KDR
Sbjct: 402 VHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFDTHEDAVAAMLKDRS 461
Query: 116 KMSWRYIELFRGSSALG 66
+ RYIELF S G
Sbjct: 462 HVQHRYIELFLNSCPKG 478
Score = 53.9 bits (128), Expect = 1e-07
Identities = 29/74 (39%), Positives = 41/74 (55%), Gaps = 4/74 (5%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAE----VKIQLGPDGKNTGEAEADFYSETDAVKAME 129
I +GLP+S T +DV FF+ R+ + L DGK G+A + SE D KA+E
Sbjct: 151 IRAQGLPWSCTVEDVLNFFSDCRIRNSENGIHFLLNRDGKRRGDALIEMESEQDVQKALE 210
Query: 128 KDRCKMSWRYIELF 87
K R M RY+E++
Sbjct: 211 KHRMYMGQRYVEVY 224
Score = 52.8 bits (125), Expect = 2e-07
Identities = 28/71 (39%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDG-KNTGEAEADFYSETDAVKAMEKDR 120
+ +RGLPYS EKD+ +FFA L + ++ + G + TGEA F A +A+ K R
Sbjct: 251 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHR 310
Query: 119 CKMSWRYIELF 87
++ RYIE+F
Sbjct: 311 EEIGNRYIEIF 321
>sp|Q12849|GRSF1_HUMAN G-rich sequence factor 1 (GRSF-1)
Length = 447
Score = 74.3 bits (181), Expect = 8e-14
Identities = 36/77 (46%), Positives = 47/77 (61%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDGKNTGEAEADFYSETDAVKAMEKDRC 117
+HMRGLP+ A +D+ FFAPL+ + ++ GK TGEA+ F + DAV AM KDR
Sbjct: 370 VHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRS 429
Query: 116 KMSWRYIELFRGSSALG 66
+ RYIELF S G
Sbjct: 430 HVHHRYIELFLNSCPKG 446
Score = 53.9 bits (128), Expect = 1e-07
Identities = 29/74 (39%), Positives = 41/74 (55%), Gaps = 4/74 (5%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAE----VKIQLGPDGKNTGEAEADFYSETDAVKAME 129
I +GLP+S T +DV FF+ R+ + L DGK G+A + SE D KA+E
Sbjct: 119 IRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALE 178
Query: 128 KDRCKMSWRYIELF 87
K R M RY+E++
Sbjct: 179 KHRMYMGQRYVEVY 192
Score = 52.8 bits (125), Expect = 2e-07
Identities = 28/71 (39%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDG-KNTGEAEADFYSETDAVKAMEKDR 120
+ +RGLPYS EKD+ +FFA L + ++ + G + TGEA F A +A+ K R
Sbjct: 219 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHR 278
Query: 119 CKMSWRYIELF 87
++ RYIE+F
Sbjct: 279 EEIGNRYIEIF 289
>sp|Q8R3C6|RBM19_MOUSE Probable RNA-binding protein 19 (RNA-binding motif protein 19)
Length = 952
Score = 59.3 bits (142), Expect = 3e-09
Identities = 30/75 (40%), Positives = 43/75 (57%)
Frame = -2
Query: 296 IHMRGLPYSATEKDVHEFFAPLRVAEVKIQLGPDGKNTGEAEADFYSETDAVKAMEKDRC 117
+ +RG P++ TEK+V EF APL+ ++I G TG D SE + KA++ +R
Sbjct: 295 VKLRGAPFNVTEKNVIEFLAPLKPVAIRIVRNAHGNKTGYVFVDLSSEEEVKKALKCNRD 354
Query: 116 KMSWRYIELFRGSSA 72
M RYIE+FR A
Sbjct: 355 YMGGRYIEVFREKQA 369
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,813,066
Number of Sequences: 369166
Number of extensions: 528859
Number of successful extensions: 1369
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1306
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1349
length of database: 68,354,980
effective HSP length: 68
effective length of database: 55,793,000
effective search space used: 1673790000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)