Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_L16-1
(700 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7SXA5|FRIL_XENLA Ferritin light chain, oocyte isoform (... 66 1e-10
sp|P42577|FRIS_LYMST Soma ferritin 62 1e-09
sp|P07798|FRI2_RANCA Ferritin, middle subunit (Ferritin M) ... 62 2e-09
sp|P19132|FRIH_RAT Ferritin heavy chain (Ferritin H subunit) 61 3e-09
sp|P29389|FRIH_CRIGR Ferritin heavy chain (Ferritin H subunit) 60 4e-09
sp|P49948|FRIH2_XENLA Ferritin heavy chain 2 (XL2-17) 60 4e-09
sp|P09528|FRIH_MOUSE Ferritin heavy chain (Ferritin H subunit) 60 6e-09
sp|P17663|FRIH1_XENLA Ferritin heavy chain 1 59 1e-08
sp|P07229|FRI1_RANCA Ferritin, higher subunit (Ferritin H) 59 1e-08
sp|P25915|FRIH_RABIT Ferritin heavy chain (Ferritin H subunit) 57 6e-08
>sp|Q7SXA5|FRIL_XENLA Ferritin light chain, oocyte isoform (B-ferritin) (XeBF) (GV-LCH)
Length = 177
Score = 65.9 bits (159), Expect = 1e-10
Identities = 43/154 (27%), Positives = 76/154 (49%), Gaps = 3/154 (1%)
Frame = -3
Query: 647 SKLINRMLQLCQGYRQVEMRCLTDELNLMSFGRLFELIRQLEGRYTEELIRFQVNRGQKV 468
+++ N LQ Y V D++ L F + F + + + + E+ ++FQ RG +V
Sbjct: 20 NRIANLELQASYLYLSVGYYFDRDDVALSKFSKFFRELSEKKRDHAEDFLKFQNKRGGRV 79
Query: 467 TWYDVKPVEQHIESGKPVEIFQSILNFEKDVHQLTLRLCKLAWEKNDLSLSSFLEDRVIL 288
DVK + E G + + LN EK ++Q L L K+A + D + +LE +
Sbjct: 80 VLQDVKKPDDD-EWGNGTKAMEVALNLEKSINQAVLDLHKIATDHTDPHMQDYLEHEFLE 138
Query: 287 RQTKVIRKRANQLRDLKR---SEDDMTPFLTSKL 195
+ K+I+K + L +L+R +E+ M +L KL
Sbjct: 139 EEVKLIKKLGDHLTNLRRVKAAEEGMGEYLFDKL 172
>sp|P42577|FRIS_LYMST Soma ferritin
Length = 174
Score = 62.4 bits (150), Expect = 1e-09
Identities = 40/150 (26%), Positives = 74/150 (49%)
Frame = -3
Query: 647 SKLINRMLQLCQGYRQVEMRCLTDELNLMSFGRLFELIRQLEGRYTEELIRFQVNRGQKV 468
++ IN L Y+ + D++ L F + F+ + E + E+L+++Q RG ++
Sbjct: 19 NRQINMELYASYSYQSMAYYFDRDDVALPGFHKFFKHQSEEEREHAEKLMKYQNKRGGRI 78
Query: 467 TWYDVKPVEQHIESGKPVEIFQSILNFEKDVHQLTLRLCKLAWEKNDLSLSSFLEDRVIL 288
D+K ++ E G +E Q L EK V+Q L L KL +D ++ FLE +
Sbjct: 79 VLQDIKKPDRD-EWGTGLEAMQVALQLEKSVNQSLLDLHKLCTSHDDAQMADFLESEFLE 137
Query: 287 RQTKVIRKRANQLRDLKRSEDDMTPFLTSK 198
Q K I++ ++ + +LKR + ++ K
Sbjct: 138 EQVKSIKELSDYITNLKRVGPGLGEYIFDK 167
>sp|P07798|FRI2_RANCA Ferritin, middle subunit (Ferritin M) (Ferritin X) (Ferritin H')
Length = 176
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/154 (31%), Positives = 75/154 (48%), Gaps = 7/154 (4%)
Frame = -3
Query: 638 INRML--QLCQGYRQVEMRCL--TDELNLMSFGRLFELIRQLEGRYTEELIRFQVNRGQK 471
+NRML +L Y M D++ L + F+ E + E+ +++Q RG +
Sbjct: 17 VNRMLNLELYASYTYSSMYAFFDRDDVALHNVAEFFKEHSHEEREHAEKFMKYQNKRGGR 76
Query: 470 VTWYDVKPVEQHIESGKPVEIFQSILNFEKDVHQLTLRLCKLAWEKNDLSLSSFLEDRVI 291
V D+K E+ E G +E Q+ L EK V+Q L L KLA +K D L FLE +
Sbjct: 77 VVLQDIKKPERD-EWGNTLEAMQAALQLEKTVNQALLDLHKLATDKVDPHLCDFLESEYL 135
Query: 290 LRQTKVIRKRANQLRDLKR---SEDDMTPFLTSK 198
Q K I++ + + +LKR E+ M +L K
Sbjct: 136 EEQVKDIKRIGDFITNLKRLGLPENGMGEYLFDK 169
>sp|P19132|FRIH_RAT Ferritin heavy chain (Ferritin H subunit)
Length = 182
Score = 60.8 bits (146), Expect = 3e-09
Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 8/155 (5%)
Frame = -3
Query: 638 INRM--LQLCQGYRQVEMRCL--TDELNLMSFGRLFELIRQLEGRYTEELIRFQVNRGQK 471
INR L+L Y + M C D++ L +F + F E + E+L++ Q RG +
Sbjct: 21 INRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80
Query: 470 VTWYDVK-PVEQHIESGKPVEIFQSILNFEKDVHQLTLRLCKLAWEKNDLSLSSFLEDRV 294
+ D+K P ESG + + L+ EK V+Q L L KLA +KND L F+E
Sbjct: 81 IFLQDIKKPDRDDWESG--LNAMRCALHLEKSVNQSLLELHKLATDKNDPHLCDFIETHY 138
Query: 293 ILRQTKVIRKRANQLRDLKR---SEDDMTPFLTSK 198
+ Q K I++ + + +L++ E M +L K
Sbjct: 139 LNEQVKSIKELGDHVTNLRKMGAPESGMAEYLFDK 173
>sp|P29389|FRIH_CRIGR Ferritin heavy chain (Ferritin H subunit)
Length = 186
Score = 60.5 bits (145), Expect = 4e-09
Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 8/155 (5%)
Frame = -3
Query: 638 INRM--LQLCQGYRQVEMRCL--TDELNLMSFGRLFELIRQLEGRYTEELIRFQVNRGQK 471
INR L+L Y + M C D++ L +F + F E + E+L++ Q RG +
Sbjct: 26 INRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 85
Query: 470 VTWYDVK-PVEQHIESGKPVEIFQSILNFEKDVHQLTLRLCKLAWEKNDLSLSSFLEDRV 294
+ D+K P ESG + + L+ EK V+Q L L KLA +KND L F+E
Sbjct: 86 IFLQDIKKPDRDDWESG--LNAMECALHLEKSVNQSLLELHKLATDKNDPHLCDFIETHY 143
Query: 293 ILRQTKVIRKRANQLRDLKR---SEDDMTPFLTSK 198
+ Q K I++ + + +L++ E M +L K
Sbjct: 144 LNEQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDK 178
>sp|P49948|FRIH2_XENLA Ferritin heavy chain 2 (XL2-17)
Length = 176
Score = 60.5 bits (145), Expect = 4e-09
Identities = 39/138 (28%), Positives = 68/138 (49%)
Frame = -3
Query: 647 SKLINRMLQLCQGYRQVEMRCLTDELNLMSFGRLFELIRQLEGRYTEELIRFQVNRGQKV 468
++++N + Y + D++ L + F+ E + E+ +++Q RG +V
Sbjct: 18 NRMVNMEMYASYVYLSMSYYFDRDDVALHHVAKFFKEQSHEEREHAEKFLKYQNKRGGRV 77
Query: 467 TWYDVKPVEQHIESGKPVEIFQSILNFEKDVHQLTLRLCKLAWEKNDLSLSSFLEDRVIL 288
D+K E+ E G +E Q+ L EK V+Q L L KLA +K D L FLE +
Sbjct: 78 VLQDIKKPERD-EWGNTLEATQAALQLEKTVNQALLDLHKLASDKVDAHLCDFLESEYLE 136
Query: 287 RQTKVIRKRANQLRDLKR 234
Q K +++ + + +LKR
Sbjct: 137 EQVKAMKQLGDYITNLKR 154
>sp|P09528|FRIH_MOUSE Ferritin heavy chain (Ferritin H subunit)
Length = 182
Score = 60.1 bits (144), Expect = 6e-09
Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 8/155 (5%)
Frame = -3
Query: 638 INRM--LQLCQGYRQVEMRCL--TDELNLMSFGRLFELIRQLEGRYTEELIRFQVNRGQK 471
INR L+L Y + M C D++ L +F + F E + E+L++ Q RG +
Sbjct: 21 INRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGR 80
Query: 470 VTWYDVK-PVEQHIESGKPVEIFQSILNFEKDVHQLTLRLCKLAWEKNDLSLSSFLEDRV 294
+ D+K P ESG + + L+ EK V+Q L L KLA +KND L F+E
Sbjct: 81 IFLQDIKKPDRDDWESG--LNAMECALHLEKSVNQSLLELHKLATDKNDPHLCDFIETYY 138
Query: 293 ILRQTKVIRKRANQLRDLKR---SEDDMTPFLTSK 198
+ Q K I++ + + +L++ E M +L K
Sbjct: 139 LSEQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDK 173
>sp|P17663|FRIH1_XENLA Ferritin heavy chain 1
Length = 176
Score = 58.9 bits (141), Expect = 1e-08
Identities = 43/139 (30%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Frame = -3
Query: 638 INRM--LQLCQGYRQVEMRCL--TDELNLMSFGRLFELIRQLEGRYTEELIRFQVNRGQK 471
INRM L++ Y + M D++ L + F+ E + E+ +++Q RG +
Sbjct: 17 INRMVNLEMYASYVYLSMSYYFDRDDVALHHVAKFFKEQSHEEREHAEKFLKYQNKRGGR 76
Query: 470 VTWYDVKPVEQHIESGKPVEIFQSILNFEKDVHQLTLRLCKLAWEKNDLSLSSFLEDRVI 291
V D+K E+ E +E Q+ L EK V+Q L L KLA +K D L FLE +
Sbjct: 77 VVLQDIKKPERD-EWSNTLEAMQAALQLEKTVNQALLDLHKLASDKVDPQLCDFLESEYL 135
Query: 290 LRQTKVIRKRANQLRDLKR 234
Q K +++ + + +LKR
Sbjct: 136 EEQVKAMKELGDYITNLKR 154
>sp|P07229|FRI1_RANCA Ferritin, higher subunit (Ferritin H)
Length = 176
Score = 58.9 bits (141), Expect = 1e-08
Identities = 44/139 (31%), Positives = 70/139 (50%), Gaps = 4/139 (2%)
Frame = -3
Query: 638 INRM--LQLCQGYRQVEMRCL--TDELNLMSFGRLFELIRQLEGRYTEELIRFQVNRGQK 471
INRM ++L Y + M D++ L + + F+ E + E+L++ Q RG +
Sbjct: 17 INRMVNMELYASYTYLSMAFYFDRDDIALHNVAKFFKEQSHEEREHAEKLMKDQNKRGGR 76
Query: 470 VTWYDVKPVEQHIESGKPVEIFQSILNFEKDVHQLTLRLCKLAWEKNDLSLSSFLEDRVI 291
+ DVK E+ E G +E Q+ L EK V+Q L L K+ +K D L FLE +
Sbjct: 77 IVLQDVKKPERD-EWGNTLEAMQAALQLEKTVNQALLDLHKVGSDKVDPHLCDFLETEYL 135
Query: 290 LRQTKVIRKRANQLRDLKR 234
Q K I++ + + +LKR
Sbjct: 136 EEQVKSIKQLGDYITNLKR 154
>sp|P25915|FRIH_RABIT Ferritin heavy chain (Ferritin H subunit)
Length = 164
Score = 56.6 bits (135), Expect = 6e-08
Identities = 40/131 (30%), Positives = 66/131 (50%), Gaps = 4/131 (3%)
Frame = -3
Query: 578 DELNLMSFGRLFELIRQLEGRYTEELIRFQVNRGQKVTWYDVK-PVEQHIESGKPVEIFQ 402
D++ L +F + F E + E+L++ Q RG ++ D+K P ESG + +
Sbjct: 26 DDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPEYDDWESG--LNAME 83
Query: 401 SILNFEKDVHQLTLRLCKLAWEKNDLSLSSFLEDRVILRQTKVIRKRANQLRDLKR---S 231
L+ EK V+Q L L KLA +KND L F+E + Q K I++ + + +L++
Sbjct: 84 CALHLEKSVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKSIKELGDHVTNLRKMGAP 143
Query: 230 EDDMTPFLTSK 198
E M +L K
Sbjct: 144 ESGMAEYLFDK 154
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,581,532
Number of Sequences: 369166
Number of extensions: 1114427
Number of successful extensions: 3164
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3082
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3164
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6073541875
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)