Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_L03
(772 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14 333 2e-91
sp|P61107|RAB14_RAT Ras-related protein Rab-14 >gi|46577643... 333 2e-91
sp|P36410|RAB4_DICDI Ras-related protein Rab4 291 1e-78
sp|P36863|YPTV4_VOLCA GTP-binding protein yptV4 (RAB2 homolog) 244 2e-64
sp|P53994|RAB2A_MOUSE Ras-related protein Rab-2A 242 7e-64
sp|Q05975|RAB2_LYMST Ras-related protein Rab-2 242 9e-64
sp|P61019|RAB2A_HUMAN Ras-related protein Rab-2A >gi|465776... 241 1e-63
sp|Q39570|YPTC4_CHLRE GTP-binding protein YPTC4 241 2e-63
sp|Q01971|RAB2A_RABIT Ras-related protein Rab-2A 241 2e-63
sp|Q8WUD1|RAB2B_HUMAN Ras-related protein Rab-2B 241 2e-63
>sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14
Length = 215
Score = 333 bits (855), Expect = 2e-91
Identities = 161/215 (74%), Positives = 183/215 (85%), Gaps = 2/215 (0%)
Frame = +2
Query: 41 MANQSYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEINGEKI 220
MA YNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIE++G+KI
Sbjct: 1 MATAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKI 60
Query: 221 KLQIWDTAGQERFRAVTRSYYRGAAGALLVYDVTRKSTFNHIHSWLTDARGLTSPNTVIF 400
KLQIWDTAGQERFRAVTRSYYRGAAGAL+VYD+TR+ST+NH+ SWLTDAR LT+PNTVI
Sbjct: 61 KLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVII 120
Query: 401 MIGNKSDMNEQRDVTYEEGKAVAEENGLMFLECSAKTGEGVEDAFIETARKIFQNIQDGS 580
+IGNK+D+ QRDVTYEE K AEENGL+FLE SAKTGE VEDAF+E A+KI+QNIQDGS
Sbjct: 121 LIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGS 180
Query: 581 VDLNSANDGVVMKNN--QAGQNSDGKSDRSSSCQC 679
+DLN+A GV K + Q G+ + + C C
Sbjct: 181 LDLNAAESGVQHKPSAPQGGRLTSEPQPQREGCGC 215
>sp|P61107|RAB14_RAT Ras-related protein Rab-14
sp|P61106|RAB14_HUMAN Ras-related protein Rab-14
Length = 215
Score = 333 bits (855), Expect = 2e-91
Identities = 161/215 (74%), Positives = 183/215 (85%), Gaps = 2/215 (0%)
Frame = +2
Query: 41 MANQSYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEINGEKI 220
MA YNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIE++G+KI
Sbjct: 1 MATTPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKI 60
Query: 221 KLQIWDTAGQERFRAVTRSYYRGAAGALLVYDVTRKSTFNHIHSWLTDARGLTSPNTVIF 400
KLQIWDTAGQERFRAVTRSYYRGAAGAL+VYD+TR+ST+NH+ SWLTDAR LT+PNTVI
Sbjct: 61 KLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVII 120
Query: 401 MIGNKSDMNEQRDVTYEEGKAVAEENGLMFLECSAKTGEGVEDAFIETARKIFQNIQDGS 580
+IGNK+D+ QRDVTYEE K AEENGL+FLE SAKTGE VEDAF+E A+KI+QNIQDGS
Sbjct: 121 LIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGS 180
Query: 581 VDLNSANDGVVMKNN--QAGQNSDGKSDRSSSCQC 679
+DLN+A GV K + Q G+ + + C C
Sbjct: 181 LDLNAAESGVQHKPSAPQGGRLTSEPQPQREGCGC 215
>sp|P36410|RAB4_DICDI Ras-related protein Rab4
Length = 205
Score = 291 bits (746), Expect = 1e-78
Identities = 143/208 (68%), Positives = 170/208 (81%)
Frame = +2
Query: 53 SYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEINGEKIKLQI 232
S+ Y YIFKYIIIGDMGVGKSCLLHQFTE KF+ D PHTIGVEFGTRI+++N +KIKLQI
Sbjct: 2 SFPYEYIFKYIIIGDMGVGKSCLLHQFTENKFVPDSPHTIGVEFGTRIVDVNNKKIKLQI 61
Query: 233 WDTAGQERFRAVTRSYYRGAAGALLVYDVTRKSTFNHIHSWLTDARGLTSPNTVIFMIGN 412
WDTAGQERFRAVTRSYYRGAAGALLVYD+TR+ T+NH+ +WLTDAR LT+PNTVI +IGN
Sbjct: 62 WDTAGQERFRAVTRSYYRGAAGALLVYDITRRITYNHLTTWLTDARNLTNPNTVIMLIGN 121
Query: 413 KSDMNEQRDVTYEEGKAVAEENGLMFLECSAKTGEGVEDAFIETARKIFQNIQDGSVDLN 592
K D+ QRDVTYEE A A++NGL+F+E SAKTGE VE+AF+ TA+ IFQ++Q+G+VDL
Sbjct: 122 KKDLEGQRDVTYEEASAFAKQNGLIFVESSAKTGENVEEAFLRTAKLIFQSVQEGNVDL- 180
Query: 593 SANDGVVMKNNQAGQNSDGKSDRSSSCQ 676
DG + KN Q K + S CQ
Sbjct: 181 -IPDGGITKN--PPQTITDKKNLFSRCQ 205
>sp|P36863|YPTV4_VOLCA GTP-binding protein yptV4 (RAB2 homolog)
Length = 213
Score = 244 bits (623), Expect = 2e-64
Identities = 121/211 (57%), Positives = 159/211 (75%), Gaps = 6/211 (2%)
Frame = +2
Query: 59 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEINGEKIKLQIWD 238
+Y+Y+FKYIIIGD GVGKSCLL QFT+K+F TIGVEFG R+I I+G++IKLQIWD
Sbjct: 2 SYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMINIDGKQIKLQIWD 61
Query: 239 TAGQERFRAVTRSYYRGAAGALLVYDVTRKSTFNHIHSWLTDARGLTSPNTVIFMIGNKS 418
TAGQE FR++TRSYYRGAAGALLVYD+TR+ TFNH+ SWL DAR +PN I +IGNK
Sbjct: 62 TAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLASWLEDARQHANPNMTIMLIGNKC 121
Query: 419 DMNEQRDVTYEEGKAVAEENGLMFLECSAKTGEGVEDAFIETARKIFQNIQDGSVDLNSA 598
D+ +R VT EEG+ A+E+GL+FLE SA+T VE+AFI TA++I++ IQDG D+++
Sbjct: 122 DLTHRRAVTTEEGEQFAKEHGLIFLETSARTAHNVEEAFINTAKEIYKKIQDGVFDVSNE 181
Query: 599 NDGVVM------KNNQAGQNSDGKSDRSSSC 673
+ G+ + QA + +G + +SSSC
Sbjct: 182 SYGIKVGYGAGNAGPQAAKPGEGDARKSSSC 212
>sp|P53994|RAB2A_MOUSE Ras-related protein Rab-2A
Length = 212
Score = 242 bits (618), Expect = 7e-64
Identities = 117/200 (58%), Positives = 155/200 (77%)
Frame = +2
Query: 62 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEINGEKIKLQIWDT 241
Y+Y+FKYIIIGD GVGKSCLL QFT+K+F TIGVEFG R+I I+G++IKLQIWDT
Sbjct: 3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDT 62
Query: 242 AGQERFRAVTRSYYRGAAGALLVYDVTRKSTFNHIHSWLTDARGLTSPNTVIFMIGNKSD 421
AGQE FR++TRSYYRGAAGALLVYD+TR+ TFNH+ +WL DAR ++ N VI +IGNKSD
Sbjct: 63 AGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSD 122
Query: 422 MNEQRDVTYEEGKAVAEENGLMFLECSAKTGEGVEDAFIETARKIFQNIQDGSVDLNSAN 601
+ +R+V EEG+A A E+GL+F+E SAKT VE+AFI TA++I++ IQ+G D+N+
Sbjct: 123 LESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEA 182
Query: 602 DGVVMKNNQAGQNSDGKSDR 661
+G+ + A N+ S++
Sbjct: 183 NGIKIGPQHAATNASHGSNQ 202
>sp|Q05975|RAB2_LYMST Ras-related protein Rab-2
Length = 212
Score = 242 bits (617), Expect = 9e-64
Identities = 116/184 (63%), Positives = 149/184 (80%)
Frame = +2
Query: 59 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEINGEKIKLQIWD 238
+Y+Y+FKYIIIGD GVGKSCLL QFT+K+F TIGVEFG R+I I+G++IKLQIWD
Sbjct: 2 SYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWD 61
Query: 239 TAGQERFRAVTRSYYRGAAGALLVYDVTRKSTFNHIHSWLTDARGLTSPNTVIFMIGNKS 418
TAGQE FR++TRSYYRGAAGALLVYD+TR+ TFNH+ +WL DAR ++ N VI +IGNKS
Sbjct: 62 TAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKS 121
Query: 419 DMNEQRDVTYEEGKAVAEENGLMFLECSAKTGEGVEDAFIETARKIFQNIQDGSVDLNSA 598
D+ +R+V EEG+A A E+GL+F+E SAKT VE+AFI TA++I+Q IQDG D+N+
Sbjct: 122 DLEARREVKKEEGEAFAREHGLIFMETSAKTAANVEEAFINTAKEIYQKIQDGVFDINNE 181
Query: 599 NDGV 610
+G+
Sbjct: 182 ANGI 185
>sp|P61019|RAB2A_HUMAN Ras-related protein Rab-2A
sp|P61105|RAB2A_CANFA Ras-related protein Rab-2A
Length = 212
Score = 241 bits (616), Expect = 1e-63
Identities = 116/194 (59%), Positives = 152/194 (78%)
Frame = +2
Query: 62 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEINGEKIKLQIWDT 241
Y+Y+FKYIIIGD GVGKSCLL QFT+K+F TIGVEFG R+I I+G++IKLQIWDT
Sbjct: 3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDT 62
Query: 242 AGQERFRAVTRSYYRGAAGALLVYDVTRKSTFNHIHSWLTDARGLTSPNTVIFMIGNKSD 421
AGQE FR++TRSYYRGAAGALLVYD+TR+ TFNH+ +WL DAR ++ N VI +IGNKSD
Sbjct: 63 AGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSD 122
Query: 422 MNEQRDVTYEEGKAVAEENGLMFLECSAKTGEGVEDAFIETARKIFQNIQDGSVDLNSAN 601
+ +R+V EEG+A A E+GL+F+E SAKT VE+AFI TA++I++ IQ+G D+N+
Sbjct: 123 LESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEA 182
Query: 602 DGVVMKNNQAGQNS 643
+G+ + A N+
Sbjct: 183 NGIKIGPQHAATNA 196
>sp|Q39570|YPTC4_CHLRE GTP-binding protein YPTC4
Length = 213
Score = 241 bits (615), Expect = 2e-63
Identities = 120/211 (56%), Positives = 158/211 (74%), Gaps = 6/211 (2%)
Frame = +2
Query: 59 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEINGEKIKLQIWD 238
+Y+Y+FKYIIIGD GVGKSCLL QFT+K+F TIGVEFG R+I I+G++IKLQIWD
Sbjct: 2 SYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMINIDGKQIKLQIWD 61
Query: 239 TAGQERFRAVTRSYYRGAAGALLVYDVTRKSTFNHIHSWLTDARGLTSPNTVIFMIGNKS 418
TAGQE FR++TRSYYRGAAGALLVYD+TR+ TFNH+ SWL DAR +PN I +IGNK
Sbjct: 62 TAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLASWLEDARQHANPNMTIMLIGNKC 121
Query: 419 DMNEQRDVTYEEGKAVAEENGLMFLECSAKTGEGVEDAFIETARKIFQNIQDGSVDLNSA 598
D+ +R VT EEG+ A+E+GL+FLE SA+T VE+AFI TA++I++ IQDG D+++
Sbjct: 122 DLTHRRAVTTEEGEQFAKEHGLIFLETSARTAHNVEEAFINTAKEIYKKIQDGVFDVSNE 181
Query: 599 NDGVVM------KNNQAGQNSDGKSDRSSSC 673
+ G+ + Q + +G + +SSSC
Sbjct: 182 SYGIKVGYGGGNAGPQTVKPGEGGAAKSSSC 212
>sp|Q01971|RAB2A_RABIT Ras-related protein Rab-2A
Length = 212
Score = 241 bits (615), Expect = 2e-63
Identities = 119/207 (57%), Positives = 155/207 (74%), Gaps = 11/207 (5%)
Frame = +2
Query: 62 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEINGEKIKLQIWDT 241
Y+Y+FKYIIIGD GVGKSCLL QFT+K+F TIGVEFG R+I I+G++IKLQIWDT
Sbjct: 3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDT 62
Query: 242 AGQERFRAVTRSYYRGAAGALLVYDVTRKSTFNHIHSWLTDARGLTSPNTVIFMIGNKSD 421
AGQE FR++TRSYYRGAAGALLVYD+TR+ TFNH+ +WL DAR ++ N VI +IGNKSD
Sbjct: 63 AGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSD 122
Query: 422 MNEQRDVTYEEGKAVAEENGLMFLECSAKTGEGVEDAFIETARKIFQNIQDGSVDLNSAN 601
+ +R+V EEG+A A E+GL+F+E SAKT VE+AFI TA++I++ IQ+G D+N+
Sbjct: 123 LESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEA 182
Query: 602 DGVVM-----------KNNQAGQNSDG 649
+G+ + NQ GQ + G
Sbjct: 183 NGIKIGPQHGATNATHAGNQGGQQAGG 209
>sp|Q8WUD1|RAB2B_HUMAN Ras-related protein Rab-2B
Length = 216
Score = 241 bits (615), Expect = 2e-63
Identities = 119/198 (60%), Positives = 153/198 (77%)
Frame = +2
Query: 62 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEINGEKIKLQIWDT 241
Y+Y+FKYIIIGD GVGKSCLL QFT+K+F TIGVEFG R++ I+G++IKLQIWDT
Sbjct: 3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDT 62
Query: 242 AGQERFRAVTRSYYRGAAGALLVYDVTRKSTFNHIHSWLTDARGLTSPNTVIFMIGNKSD 421
AGQE FR++TRSYYRGAAGALLVYD+TR+ TFNH+ SWL DAR +S N VI +IGNKSD
Sbjct: 63 AGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSD 122
Query: 422 MNEQRDVTYEEGKAVAEENGLMFLECSAKTGEGVEDAFIETARKIFQNIQDGSVDLNSAN 601
+ +RDV EEG+A A E+GL+F+E SAKT VE+AFI TA++I++ IQ G D+++
Sbjct: 123 LESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEA 182
Query: 602 DGVVMKNNQAGQNSDGKS 655
+G+ + Q+ S G S
Sbjct: 183 NGIKIGPQQSISTSVGPS 200
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,567,159
Number of Sequences: 369166
Number of extensions: 1899131
Number of successful extensions: 6848
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6109
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6348
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7163732800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)