Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_K23
(799 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9ULA0|DNPEP_HUMAN Aspartyl aminopeptidase 263 4e-70
sp|Q9Z2W0|DNPEP_MOUSE Aspartyl aminopeptidase 257 2e-68
sp|Q19087|DNPEP_CAEEL Putative aspartyl aminopeptidase 218 2e-56
sp|O36014|DNPEP_SCHPO Putative aspartyl aminopeptidase 210 3e-54
sp|P38821|DNPEP_YEAST Putative aspartyl aminopeptidase 190 3e-48
sp|Q87YC5|APEB_PSESM Probable M18-family aminopeptidase 2 184 3e-46
sp|Q9HYZ3|APEB_PSEAE Probable M18-family aminopeptidase 2 181 2e-45
sp|Q88M44|APEB_PSEPK Probable M18-family aminopeptidase 2 174 2e-43
sp|Q50022|APEB_MYCLE Probable M18-family aminopeptidase 2 149 9e-36
sp|P59951|APEB_MYCBO Probable M18-family aminopeptidase 2 145 2e-34
>sp|Q9ULA0|DNPEP_HUMAN Aspartyl aminopeptidase
Length = 475
Score = 263 bits (672), Expect = 4e-70
Identities = 128/239 (53%), Positives = 178/239 (74%), Gaps = 3/239 (1%)
Frame = +2
Query: 2 LCLADCQPSTIGGIHQEFVFAPRLDNLFNCYTSVQALVESLE---SVSDDTNIRAVCLFD 172
LCLAD QP+ +GG + EF+FAPRLDNL +C+ ++QAL++S S++ + ++R V L+D
Sbjct: 240 LCLADTQPAVLGGAYDEFIFAPRLDNLHSCFCALQALIDSCAGPGSLATEPHVRMVTLYD 299
Query: 173 NEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANSLLISADQAHGVHP 352
NEE+GS+SAQGAQS TEL+LRR+ + CQ+ + +E AI S +ISAD AH VHP
Sbjct: 300 NEEVGSESAQGAQSLLTELVLRRI-SASCQHP-----TAFEEAIPKSFMISADMAHAVHP 353
Query: 353 NYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPLQNFVVRQDMAC 532
NY +KHE H+PL H+G V+K+NS QRYASNA++ +++REVANK +VPLQ+ +VR D C
Sbjct: 354 NYLDKHEENHRPLFHKGPVIKVNSKQRYASNAVSEALIREVANKVKVPLQDLMVRNDTPC 413
Query: 533 GSTIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKGFFNLYPDLSRRV 709
G+TIGPI+++ +GL +D+G PQL+MHS REM + V Q + LFKGFF L+P LS +
Sbjct: 414 GTTIGPILASRLGLRVLDLGSPQLAMHSIREMACTTGVLQTLTLFKGFFELFPSLSHNL 472
>sp|Q9Z2W0|DNPEP_MOUSE Aspartyl aminopeptidase
Length = 473
Score = 257 bits (657), Expect = 2e-68
Identities = 125/239 (52%), Positives = 173/239 (72%), Gaps = 3/239 (1%)
Frame = +2
Query: 2 LCLADCQPSTIGGIHQEFVFAPRLDNLFNCYTSVQALVESLES---VSDDTNIRAVCLFD 172
LCLAD QP+ +GG ++EF+FAPRLDNL +C+ ++QAL++S S ++ D ++R V L+D
Sbjct: 238 LCLADTQPAVLGGAYEEFIFAPRLDNLHSCFCALQALIDSCASPASLARDPHVRMVTLYD 297
Query: 173 NEEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANSLLISADQAHGVHP 352
NEE+GS+SAQGAQS TELILRR+ + + +E AI S +ISAD AH VHP
Sbjct: 298 NEEVGSESAQGAQSLLTELILRRI------SASPQRLTAFEEAIPKSFMISADMAHAVHP 351
Query: 353 NYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPLQNFVVRQDMAC 532
NY +KHE H+P H+G V+K+NS QRYASNA++ S++REVA + VPLQ+ +VR D C
Sbjct: 352 NYSDKHEENHRPSFHKGPVIKVNSKQRYASNAVSESMIREVAGQVGVPLQDLMVRNDSPC 411
Query: 533 GSTIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKGFFNLYPDLSRRV 709
G+TIGPI+++ +GL +D+G PQL+MHS RE + V Q + LFKGFF L+P +SR +
Sbjct: 412 GTTIGPILASRLGLRVLDLGSPQLAMHSIRETACTTGVLQTLTLFKGFFELFPSVSRNL 470
>sp|Q19087|DNPEP_CAEEL Putative aspartyl aminopeptidase
Length = 470
Score = 218 bits (554), Expect = 2e-56
Identities = 113/228 (49%), Positives = 147/228 (64%), Gaps = 2/228 (0%)
Frame = +2
Query: 2 LCLADCQPSTIGGIHQEFVFAPRLDNLFNCYTSVQALVESL--ESVSDDTNIRAVCLFDN 175
L L D + I G+ EF+ RLDN YT++ L+ESL ES +D IR FDN
Sbjct: 239 LYLYDTNKAAIVGMEDEFISGARLDNQVGTYTAISGLLESLTGESFKNDPQIRIAACFDN 298
Query: 176 EEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANSLLISADQAHGVHPN 355
EE+GS SA GA S+FTE +LRR+ S + +E AI S+LISADQAH HPN
Sbjct: 299 EEVGSDSAMGASSSFTEFVLRRL-------SAGGSTTAFEEAIGKSMLISADQAHATHPN 351
Query: 356 YEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPLQNFVVRQDMACG 535
Y KHE H+P H G+V+K+N NQRYA+ + T + L++VA +++VPLQ VVR D CG
Sbjct: 352 YSAKHEENHRPAFHGGVVVKVNVNQRYATTSTTHAALKQVAFEAQVPLQVVVVRNDSPCG 411
Query: 536 STIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKGFF 679
ST+GPI++ +GL TVDVG PQL+MHS RE D SS+ QA L+ F+
Sbjct: 412 STVGPILATKLGLQTVDVGCPQLAMHSIREFADTSSIYQATTLYSTFY 459
>sp|O36014|DNPEP_SCHPO Putative aspartyl aminopeptidase
Length = 467
Score = 210 bits (535), Expect = 3e-54
Identities = 110/240 (45%), Positives = 160/240 (66%), Gaps = 2/240 (0%)
Frame = +2
Query: 2 LCLADCQPSTIGGIHQEFVFAPRLDNLFNCYTSVQALVESLE--SVSDDTNIRAVCLFDN 175
L L D + + +GGIH+EFVF+PRLDNL + + QAL +SLE S+ +++ +R V FD+
Sbjct: 232 LILGDAEKARLGGIHEEFVFSPRLDNLGMTFCASQALTKSLENNSLDNESCVRVVPSFDH 291
Query: 176 EEIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANSLLISADQAHGVHPN 355
EEIGS SAQGA+S F +L+R IC+ G S S + ++ S L+SAD AH +HPN
Sbjct: 292 EEIGSVSAQGAESTFLPAVLQR----ICE-LGKES-SLFSISMVKSFLVSADMAHAMHPN 345
Query: 356 YEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPLQNFVVRQDMACG 535
Y ++E + P ++G V+K+N+NQRY +N+ +L++VA ++VP+Q+FVVR D CG
Sbjct: 346 YSSRYENSNTPFLNKGTVIKVNANQRYTTNSAGIVLLKKVAQLADVPIQSFVVRNDSPCG 405
Query: 536 STIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKGFFNLYPDLSRRVTL 715
STIGP ++A G+ T+D+G P LSMHSCREM E AV LF FF + +L ++ +
Sbjct: 406 STIGPKLAAMTGMRTLDLGNPMLSMHSCREMCGSKDFEYAVVLFSSFFQNFANLEEKIII 465
>sp|P38821|DNPEP_YEAST Putative aspartyl aminopeptidase
Length = 490
Score = 190 bits (483), Expect = 3e-48
Identities = 108/244 (44%), Positives = 150/244 (61%), Gaps = 6/244 (2%)
Frame = +2
Query: 2 LCLADCQPSTIGGIHQEFVFAPRLDNLFNCYTSVQALVESLESVSD-DTNIRAVCLFDNE 178
L L D ST+GG + EFVF+ RLDNL +C+TS+ L + ++ D ++ IR + FD+E
Sbjct: 249 LILYDHNASTLGGFNDEFVFSGRLDNLTSCFTSMHGLTLAADTEIDRESGIRLMACFDHE 308
Query: 179 EIGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSH-YERAI----ANSLLISADQAHG 343
EIGS SAQGA S F IL R+ +I + G + AI A S +S+D AH
Sbjct: 309 EIGSSSAQGADSNFLPNILERL--SILKGDGSDQTKPLFHSAILETSAKSFFLSSDVAHA 366
Query: 344 VHPNYEEKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPLQNFVVRQD 523
VHPNY K+E QHKPL G V+KIN+NQRY +N+ +++ +A ++VPLQ FVV D
Sbjct: 367 VHPNYANKYESQHKPLLGGGPVIKINANQRYMTNSPGLVLVKRLAEAAKVPLQLFVVAND 426
Query: 524 MACGSTIGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKGFFNLYPDLSR 703
CGSTIGPI+++ G+ T+D+G P LSMHS RE + +E + LFK FF Y +
Sbjct: 427 SPCGSTIGPILASKTGIRTLDLGNPVLSMHSIRETGGSADLEFQIKLFKEFFERYTSIES 486
Query: 704 RVTL 715
+ +
Sbjct: 487 EIVV 490
>sp|Q87YC5|APEB_PSESM Probable M18-family aminopeptidase 2
Length = 429
Score = 184 bits (466), Expect = 3e-46
Identities = 99/226 (43%), Positives = 139/226 (61%)
Frame = +2
Query: 2 LCLADCQPSTIGGIHQEFVFAPRLDNLFNCYTSVQALVESLESVSDDTNIRAVCLFDNEE 181
L D Q + + G++ +F+ RLDNL +C+ +QAL L + SD+T + VC D+EE
Sbjct: 212 LSFYDTQSAAVVGLNGDFLAGARLDNLLSCFAGMQAL---LNTESDETAL-LVCT-DHEE 266
Query: 182 IGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANSLLISADQAHGVHPNYE 361
+GS SA GA A E I++R++ S Y R I SLLISAD AHG+HPNY
Sbjct: 267 VGSSSACGADGAMLEQIVQRLL---------PSSEDYVRTIQKSLLISADNAHGIHPNYA 317
Query: 362 EKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPLQNFVVRQDMACGST 541
+KH+ H P + G V+K+NSNQRYA+N+ T R + EVP+Q+FVVR DM CGST
Sbjct: 318 DKHDANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAEEVPVQSFVVRSDMGCGST 377
Query: 542 IGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKGFF 679
IGPI ++++G+ TVD+G P +MHS RE+ + V + F+
Sbjct: 378 IGPITASHLGIRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFY 423
>sp|Q9HYZ3|APEB_PSEAE Probable M18-family aminopeptidase 2
Length = 429
Score = 181 bits (459), Expect = 2e-45
Identities = 96/226 (42%), Positives = 134/226 (59%)
Frame = +2
Query: 2 LCLADCQPSTIGGIHQEFVFAPRLDNLFNCYTSVQALVESLESVSDDTNIRAVCLFDNEE 181
L D Q + + G++ EF+ RLDNL +C+ ++AL+ + D N VC D+EE
Sbjct: 212 LSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNA----EGDENCILVCT-DHEE 266
Query: 182 IGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANSLLISADQAHGVHPNYE 361
+GS S GA F E +LRR++ + RAI SLL+SAD AHGVHPNY
Sbjct: 267 VGSCSHCGADGPFLEQVLRRLL---------PEGDAFSRAIQRSLLVSADNAHGVHPNYA 317
Query: 362 EKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPLQNFVVRQDMACGST 541
++H+ H P + G V+KINSNQRYA+N+ T R + SEVP+Q+FV R DM CGST
Sbjct: 318 DRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGCGST 377
Query: 542 IGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKGFF 679
IGPI ++ +G+ TVD+G P +MHS RE+ + V + F+
Sbjct: 378 IGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFY 423
>sp|Q88M44|APEB_PSEPK Probable M18-family aminopeptidase 2
Length = 429
Score = 174 bits (442), Expect = 2e-43
Identities = 95/226 (42%), Positives = 136/226 (60%)
Frame = +2
Query: 2 LCLADCQPSTIGGIHQEFVFAPRLDNLFNCYTSVQALVESLESVSDDTNIRAVCLFDNEE 181
L D Q + + G++ +F+ RLDNL +CY +QAL L + SD+T + VC D+EE
Sbjct: 212 LSFYDTQDAALIGLNGDFIAGARLDNLLSCYAGLQAL---LAADSDETCV-LVCN-DHEE 266
Query: 182 IGSQSAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANSLLISADQAHGVHPNYE 361
+GS SA GA E L+R++ Y R + SL++SAD AHGVHPNY
Sbjct: 267 VGSCSACGADGPMLEQTLQRLL---------PDGDTYVRTVQRSLMVSADNAHGVHPNYA 317
Query: 362 EKHERQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPLQNFVVRQDMACGST 541
+KH+ H P + G V+K+N+NQRYA+N+ T R + EVP+Q+FVVR DM CGST
Sbjct: 318 DKHDGNHGPKLNAGPVIKVNNNQRYATNSETAGFFRHLCMAEEVPVQSFVVRSDMGCGST 377
Query: 542 IGPIMSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKGFF 679
IGPI ++++G+ TVD+G P +MHS RE+ + V + F+
Sbjct: 378 IGPITASHLGVRTVDIGLPTFAMHSIRELCGSHDLAHLVKVLTAFY 423
>sp|Q50022|APEB_MYCLE Probable M18-family aminopeptidase 2
Length = 426
Score = 149 bits (376), Expect = 9e-36
Identities = 89/223 (39%), Positives = 119/223 (53%)
Frame = +2
Query: 14 DCQPSTIGGIHQEFVFAPRLDNLFNCYTSVQALVESLESVSDDTNIRAVCLFDNEEIGSQ 193
D PS + G + APRLDN +CY ++AL L SV D + + LFD+EE+GS
Sbjct: 209 DLVPSMVIGADANLLSAPRLDNQVSCYAGMEAL---LASVPHDC-LPVLALFDHEEVGST 264
Query: 194 SAQGAQSAFTELILRRVVNTICQNCGVASFSHYERAIANSLLISADQAHGVHPNYEEKHE 373
S +GA+S +L R+V Y R + SLL+SAD AH HPNY E HE
Sbjct: 265 SDRGARSNLLSTVLERIVLA-----AGGGRDDYLRRLPASLLVSADMAHATHPNYPECHE 319
Query: 374 RQHKPLPHQGIVLKINSNQRYASNAMTTSILREVANKSEVPLQNFVVRQDMACGSTIGPI 553
H + G VLK++ N RYA++ T + ++ V LQ + R D CGSTIGP+
Sbjct: 320 PSHLIEVNAGPVLKVHPNLRYATDGRTAAAFEVACQQAGVRLQRYEHRADRPCGSTIGPL 379
Query: 554 MSANMGLATVDVGGPQLSMHSCREMTDVSSVEQAVHLFKGFFN 682
SA G+ TVDVG QL+MHS RE+ V + FF+
Sbjct: 380 ASARTGIPTVDVGAAQLAMHSARELMGAHDVAVYSAALQAFFS 422
>sp|P59951|APEB_MYCBO Probable M18-family aminopeptidase 2
Length = 433
Score = 145 bits (365), Expect = 2e-34
Identities = 78/205 (38%), Positives = 115/205 (56%), Gaps = 3/205 (1%)
Frame = +2
Query: 62 APRLDNLFNCYTSVQALVESLESVSDDTNIRAVCLFDNEEIGSQSAQGAQSAFTELILRR 241
APRLDN +CY ++AL+ + + + +FD+EE+GS S GAQS +L R
Sbjct: 226 APRLDNQASCYAGMEALLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDLLSSVLER 285
Query: 242 VVNTICQNCGVASFSHYERAIANSLLISADQAHGVHPNYEEKHERQHKPLPHQGIVLKIN 421
+V + + R + S+L SAD AH HPNY ++HE H + G VLK++
Sbjct: 286 IVLA-----AGGTREDFLRRLTTSMLASADMAHATHPNYPDRHEPSHPIEVNAGPVLKVH 340
Query: 422 SNQRYASNAMTTSILREVANKSEVPLQNFVVRQDMACGSTIGPIMSANMGLATVDVGGPQ 601
N RYA++ T + ++ VP+Q + R D+ CGSTIGP+ +A G+ TVDVG Q
Sbjct: 341 PNLRYATDGRTAAAFALACQRAGVPMQRYEHRADLPCGSTIGPLAAARTGIPTVDVGAAQ 400
Query: 602 LSMHSCREMT---DVSSVEQAVHLF 667
L+MHS RE+ DV++ A+ F
Sbjct: 401 LAMHSARELMGAHDVAAYSAALQAF 425
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,462,424
Number of Sequences: 369166
Number of extensions: 1945338
Number of successful extensions: 5015
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4758
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4985
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7522142940
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)