Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_K14
(851 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9WUM3|COR1B_MOUSE Coronin-1B (Coronin-2) 147 5e-35
sp|Q9BR76|CO1B_HUMAN Coronin-1B (Coronin-2) 145 1e-34
sp|Q9ULV4|COR1C_HUMAN Coronin-1C (Coronin-3) (hCRNN4) 144 4e-34
sp|O89046|COR1B_RAT Coronin-1B (Coronin-2) 144 4e-34
sp|Q9XS70|COR1B_RABIT Coronin-1B (Coroninse) (Coronin-like ... 143 5e-34
sp|Q9WUM4|COR1C_MOUSE Coronin-1C (Coronin-3) 142 2e-33
sp|Q920M5|CORO6_MOUSE Coronin-6 (Clipin E) 138 2e-32
sp|Q920J3|CORO6_RAT Coronin-6 135 2e-31
sp|Q21624|CORO_CAEEL Coronin-like protein cor-1 132 9e-31
sp|Q92176|COR1A_BOVIN Coronin-1A (Coronin-like protein p57)... 129 1e-29
>sp|Q9WUM3|COR1B_MOUSE Coronin-1B (Coronin-2)
Length = 484
Score = 147 bits (370), Expect = 5e-35
Identities = 80/282 (28%), Positives = 148/282 (52%), Gaps = 2/282 (0%)
Frame = +1
Query: 7 IRHSKFKNIYGDPKKKEQCFDQIKLKVKGAEPPLAAVNAKYLAVLINCSTVDV-MIRPLE 183
+R SKF++++G P K +QC++ I++ + AVN K+LAV++ S M+ PL
Sbjct: 7 VRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLN 66
Query: 184 EVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDS 363
+ GR++ + I+WCP +D+++ G ++ + + +IP+ G+T +
Sbjct: 67 KTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVV 126
Query: 364 EIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEI-KL 540
++ + + I+ WHPT N +L++ D +++W+ E+L + L
Sbjct: 127 VLEGHTKRVGIIT--WHPTARNVLLSA----------GCDNVVLIWNVGTAEELYRLDSL 174
Query: 541 NNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLI 720
+ + ++S+N+NGS RIID R V + H+ AR ++L +G +
Sbjct: 175 HPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKV 234
Query: 721 FSTGYSSTTIREYALWDENDLSNPIELIDLDANSGVLYPIYD 846
F+TG+S + R+ ALWD +L P+ L +LD+++G L P YD
Sbjct: 235 FTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYD 276
>sp|Q9BR76|CO1B_HUMAN Coronin-1B (Coronin-2)
Length = 489
Score = 145 bits (367), Expect = 1e-34
Identities = 79/282 (28%), Positives = 148/282 (52%), Gaps = 2/282 (0%)
Frame = +1
Query: 7 IRHSKFKNIYGDPKKKEQCFDQIKLKVKGAEPPLAAVNAKYLAVLINCSTVDV-MIRPLE 183
+R SKF++++G P K +QC++ I++ + AVN K+LAV++ S ++ PL
Sbjct: 7 VRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLS 66
Query: 184 EVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDS 363
+ GR++ + I+WCP +D+++ G ++ + + +IP+ G+T +
Sbjct: 67 KTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVV 126
Query: 364 EIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEI-KL 540
++ + + I+ WHPT N +L++ D +++W+ E+L + L
Sbjct: 127 VLEGHTKRVGII--AWHPTARNVLLSA----------GCDNVVLIWNVGTAEELYRLDSL 174
Query: 541 NNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLI 720
+ + ++S+N+NGS RIID R V + H+ AR ++L +G +
Sbjct: 175 HPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKV 234
Query: 721 FSTGYSSTTIREYALWDENDLSNPIELIDLDANSGVLYPIYD 846
F+TG+S + R+ ALWD +L P+ L +LD+++G L P YD
Sbjct: 235 FTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYD 276
>sp|Q9ULV4|COR1C_HUMAN Coronin-1C (Coronin-3) (hCRNN4)
Length = 474
Score = 144 bits (362), Expect = 4e-34
Identities = 76/282 (26%), Positives = 148/282 (52%), Gaps = 2/282 (0%)
Frame = +1
Query: 7 IRHSKFKNIYGDPKKKEQCFDQIKLKVKGAEPPLAAVNAKYLAVLINCSTVDV-MIRPLE 183
+R SKF++++G K +QC+D I++ + AVN +++A++I S ++ PL
Sbjct: 5 VRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLH 64
Query: 184 EVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDS 363
+ GR++ + I+WCP +D ++ G ++ + + +IP+ G+T ++ +
Sbjct: 65 KTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLT--LSLTEP 122
Query: 364 EIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEIK-L 540
+ S + WHPT N +L++ D +I+W+ E L+ + +
Sbjct: 123 VVILEGHSKRVGIVAWHPTARNVLLSA----------GCDNAIIIWNVGTGEALINLDDM 172
Query: 541 NNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLI 720
++ + ++S+N NGS + R+ID R E V ++ H+ AR ++L +G +
Sbjct: 173 HSDMIYNVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNV 232
Query: 721 FSTGYSSTTIREYALWDENDLSNPIELIDLDANSGVLYPIYD 846
F+TG+S + R+ ALW+ ++ PI L ++D ++GVL P YD
Sbjct: 233 FTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYD 274
>sp|O89046|COR1B_RAT Coronin-1B (Coronin-2)
Length = 484
Score = 144 bits (362), Expect = 4e-34
Identities = 81/284 (28%), Positives = 149/284 (52%), Gaps = 4/284 (1%)
Frame = +1
Query: 7 IRHSKFKNIYGDPKKKEQCFDQIKLKVKGAEPPLAAVNAKYLAVLINCSTVDV-MIRPLE 183
+R SKF++++G P K +QC++ I++ + AVN K+LAV++ S M+ PL
Sbjct: 7 VRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLN 66
Query: 184 EVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDS 363
+ GR++ + I+WCP +D+++ G ++ + + +IP+ G+T +
Sbjct: 67 KTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVV 126
Query: 364 EIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEI-KL 540
++ + + I+ WHPT N +L++ D +++W+ E+L + L
Sbjct: 127 VLEGHTKRVGIIT--WHPTARNVLLSA----------GCDNVVLIWNVGTAEELYRLDSL 174
Query: 541 NNCYLTSLSFNYNGSK--VVCTDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNG 714
+ + ++S+N+NGS C D S RIID R V + H+ AR ++L +G
Sbjct: 175 HPDLIYNVSWNHNGSLFCTACKDKS--VRIIDPRRGTLVAEREKAHEGARPMRAIFLADG 232
Query: 715 LIFSTGYSSTTIREYALWDENDLSNPIELIDLDANSGVLYPIYD 846
+F+ G+S + R+ ALWD + P+ L +LD+++G L P YD
Sbjct: 233 KVFTAGFSRMSERQLALWDPENFEEPMALQELDSSNGALLPFYD 276
>sp|Q9XS70|COR1B_RABIT Coronin-1B (Coroninse) (Coronin-like protein pp66)
Length = 486
Score = 143 bits (361), Expect = 5e-34
Identities = 80/282 (28%), Positives = 146/282 (51%), Gaps = 2/282 (0%)
Frame = +1
Query: 7 IRHSKFKNIYGDPKKKEQCFDQIKLKVKGAEPPLAAVNAKYLAVLINCSTVDV-MIRPLE 183
+R SKF++++G P K +QC++ I++ + AVN K+LAV++ S ++ PL
Sbjct: 7 VRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLS 66
Query: 184 EVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDS 363
+ GR++ + IEWCP +D ++ G ++ + + +IP+ G+T +
Sbjct: 67 KTGRIDKAYPTVCGHTGPVLDIEWCPHNDGVIASGSEDCTVMVWQIPEDGLTSPLTEPVV 126
Query: 364 EIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEI-KL 540
++ + + I+ WHPT N +L++ D +++W+ E+L + L
Sbjct: 127 VLEGHTKRVGIVT--WHPTARNVLLSA----------GCDNVVLIWNVGTAEELYRLDSL 174
Query: 541 NNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLI 720
+ + ++S+N NGS RIID R V + H+ AR ++L +G +
Sbjct: 175 HPDLIYNVSWNRNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKV 234
Query: 721 FSTGYSSTTIREYALWDENDLSNPIELIDLDANSGVLYPIYD 846
F+TG+S + R+ ALWD +L P+ L +LD+++G L P YD
Sbjct: 235 FTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYD 276
>sp|Q9WUM4|COR1C_MOUSE Coronin-1C (Coronin-3)
Length = 474
Score = 142 bits (357), Expect = 2e-33
Identities = 75/282 (26%), Positives = 148/282 (52%), Gaps = 2/282 (0%)
Frame = +1
Query: 7 IRHSKFKNIYGDPKKKEQCFDQIKLKVKGAEPPLAAVNAKYLAVLINCSTVDV-MIRPLE 183
+R SKF++++G K +QC+D I++ + AVN +++A++I S ++ PL
Sbjct: 5 VRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLH 64
Query: 184 EVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDS 363
+ GR++ + I+WCP +D ++ G ++ + + +IP+ G+T ++ +
Sbjct: 65 KTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLT--LSLTEP 122
Query: 364 EIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEIK-L 540
+ S + WHPT N +L++ D +I+W+ E L+ + +
Sbjct: 123 VVILEGHSKRVGIVAWHPTARNVLLSA----------GCDNAIIIWNVGTGEALINLDDM 172
Query: 541 NNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLI 720
++ + ++S++ NGS + R+ID R E V ++ H+ AR ++L +G +
Sbjct: 173 HSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNV 232
Query: 721 FSTGYSSTTIREYALWDENDLSNPIELIDLDANSGVLYPIYD 846
F+TG+S + R+ ALW+ ++ PI L ++D ++GVL P YD
Sbjct: 233 FTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYD 274
>sp|Q920M5|CORO6_MOUSE Coronin-6 (Clipin E)
Length = 471
Score = 138 bits (348), Expect = 2e-32
Identities = 84/282 (29%), Positives = 142/282 (50%), Gaps = 2/282 (0%)
Frame = +1
Query: 7 IRHSKFKNIYGDPKKKEQCFDQIKLKVKGAEPPLAAVNAKYLAVLINCSTVDVMI-RPLE 183
+R SKF++++G K +Q ++ I++ + AVN K+LA+++ I PL
Sbjct: 6 VRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLA 65
Query: 184 EVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDS 363
+ GRV+ + + I+WCP +D+++ + + + +IPD T V N +
Sbjct: 66 KTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASASDDTTVMVWQIPD--YTPVRNITEP 123
Query: 364 EIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEIK-L 540
I S + WHPT N +L++ G D +I+W+ E LL + +
Sbjct: 124 VITLEGHSKRVGILSWHPTARNVLLSAGG----------DNVIIIWNVGTGEVLLSLDDI 173
Query: 541 NNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLI 720
+ + S+ +N NGS + T RIID R S+ V + A H+ AR V+ +G +
Sbjct: 174 HPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQVVAERARPHEGARPLRAVFTADGKL 233
Query: 721 FSTGYSSTTIREYALWDENDLSNPIELIDLDANSGVLYPIYD 846
STG+S + R+ ALWD N+ P+ L ++D ++GVL P YD
Sbjct: 234 LSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYD 275
>sp|Q920J3|CORO6_RAT Coronin-6
Length = 472
Score = 135 bits (339), Expect = 2e-31
Identities = 83/282 (29%), Positives = 140/282 (49%), Gaps = 2/282 (0%)
Frame = +1
Query: 7 IRHSKFKNIYGDPKKKEQCFDQIKLKVKGAEPPLAAVNAKYLAVLINCSTVDVMI-RPLE 183
+R SKF++++G K +Q ++ I++ + AVN K+LA+++ I PL
Sbjct: 6 VRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLA 65
Query: 184 EVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDS 363
+ GRV+ + I I+WCP +D+++ + + + +IPD T V N +
Sbjct: 66 KTGRVDKNYPLITGHTGPVLDIDWCPHNDNVIASPSDDTTVMVWQIPD--YTPVRNITEP 123
Query: 364 EIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEIK-L 540
I S + WHPT N +L++ G D +I+W+ E LL + +
Sbjct: 124 VITLEGHSKRVGILSWHPTARNVLLSAGG----------DNVIIIWNVGTGEVLLSLDDI 173
Query: 541 NNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLI 720
+ + S+ +N NGS + T RIID R S+ V + H+ R V+ + G I
Sbjct: 174 HPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQVVAERFAAHEGMRPMRAVFTRLGHI 233
Query: 721 FSTGYSSTTIREYALWDENDLSNPIELIDLDANSGVLYPIYD 846
F+TG++ + RE LWD N+ P+ L ++D ++GVL P YD
Sbjct: 234 FTTGFTRMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYD 275
>sp|Q21624|CORO_CAEEL Coronin-like protein cor-1
Length = 605
Score = 132 bits (333), Expect = 9e-31
Identities = 80/280 (28%), Positives = 141/280 (50%)
Frame = +1
Query: 7 IRHSKFKNIYGDPKKKEQCFDQIKLKVKGAEPPLAAVNAKYLAVLINCSTVDVMIRPLEE 186
+R SKF++++ P K E C I++ + VN K++A + + M+ P+ +
Sbjct: 5 VRQSKFRHVFCKPVKHESCMSDIRVTEITWDSLFCDVNPKFIAFINRGAGGPFMVIPVNK 64
Query: 187 VGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDSE 366
+GRV+ D + A + + W P +D+++ ++ + IPD G+ N +
Sbjct: 65 IGRVDKDYPFVDAHKAPCLEVAWSPFNDNVIASCSEDTTCKVWVIPDRGLNR--NLSEPA 122
Query: 367 IKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEIKLNN 546
++ + WHP N +LT+ G + +W+ E LLEI +
Sbjct: 123 VELTGHQKRVNTIAWHPVANNVLLTAGGENV----------MFMWNVGTGEALLEISGHP 172
Query: 547 CYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLIFS 726
+ S++FN++GS+ V T RI+D + E V+ E M H+ + Q +++K+GLI S
Sbjct: 173 DQIWSINFNFDGSQFVTTCKDKKIRILDSHTGE-VVHEGMGHEGVKPQRAIFVKDGLILS 231
Query: 727 TGYSSTTIREYALWDENDLSNPIELIDLDANSGVLYPIYD 846
TG++ + R YAL DLS PI +LD ++GV++P YD
Sbjct: 232 TGFTKRSERLYALRAPEDLSTPIVEEELDTSNGVVFPFYD 271
>sp|Q92176|COR1A_BOVIN Coronin-1A (Coronin-like protein p57) (Coronin-like protein A)
(CLIPINA) (Tryptophan aspartate-containing coat protein)
(TACO)
Length = 461
Score = 129 bits (323), Expect = 1e-29
Identities = 74/283 (26%), Positives = 145/283 (51%), Gaps = 3/283 (1%)
Frame = +1
Query: 7 IRHSKFKNIYGDPKKKEQCFDQIKLKVKGAEPPLAAVNAKYLAVLINCSTVDV-MIRPLE 183
+R SKF++++G P K +QC++ +++ + AVN K++A++ S ++ PL
Sbjct: 6 VRSSKFRHVFGQPAKADQCYEDVRVSQNTWDSGFCAVNPKFVALICEASGGGAFLVLPLG 65
Query: 184 EVGRVESDPKGIKAAISLPTCIEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDS 363
+ GRV+ + + + I WCP +D+++ G ++ + + IPDGG+T +
Sbjct: 66 KTGRVDKNVPMVCGHTAPVLDIAWCPHNDNVIASGSEDCSVMVWEIPDGGLTLPLREPVV 125
Query: 364 EIKWNCESGSILNAVWHPTVGNAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEI--K 537
++ + + I+ WHPT N +L++ D +++WD +L +
Sbjct: 126 TLEGHTKRVGIV--AWHPTAQNVLLSA----------GCDNVILVWDVGTGVAVLTLGSD 173
Query: 538 LNNCYLTSLSFNYNGSKVVCTDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGL 717
++ + S+ ++ +G+ + + RII+ R V ++ H+ R V++ +G
Sbjct: 174 VHPDTIYSVDWSRDGALICTSCRDKRVRIIEPRKGTIVAEKDRPHEGTRPVRAVFVSDGK 233
Query: 718 IFSTGYSSTTIREYALWDENDLSNPIELIDLDANSGVLYPIYD 846
I +TG+S + R+ ALWD L P+ L +LD +SGVL P +D
Sbjct: 234 ILTTGFSRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFD 276
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.317 0.135 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,772,412
Number of Sequences: 369166
Number of extensions: 1991711
Number of successful extensions: 5418
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5167
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5358
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8390082510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)