Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_023_K08 (412 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P31230|MCA1_MOUSE Multisynthetase complex auxiliary comp... 62 6e-10 sp|Q12904|MCA1_HUMAN Multisynthetase complex auxiliary comp... 61 1e-09 sp|O54873|MCA1_CRIGR Multisynthetase complex auxiliary comp... 60 1e-09 sp|Q20970|SYM_CAEEL Methionyl-tRNA synthetase (Methionine--... 54 2e-07 sp|Q9SVN5|SYM_ARATH Probable methionyl-tRNA synthetase (Met... 50 1e-06 sp|P54577|SYYC_HUMAN Tyrosyl-tRNA synthetase, cytoplasmic (... 48 9e-06 sp|Q91WQ3|SYYC_MOUSE Tyrosyl-tRNA synthetase, cytoplasmic (... 47 1e-05 sp|Q29465|SYYC_BOVIN Tyrosyl-tRNA synthetase, cytoplasmic (... 46 3e-05 sp|P46672|G4P1_YEAST GU4 nucleic-binding protein 1 (G4p1 pr... 31 0.84 sp|Q922D8|C1TC_MOUSE C-1-tetrahydrofolate synthase, cytopla... 30 2.4
>sp|P31230|MCA1_MOUSE Multisynthetase complex auxiliary component p43 [Contains: Endothelial monocyte-activating polypeptide II (EMAP-II) (Small inducible cytokine subfamily E member 1)] Length = 310 Score = 61.6 bits (148), Expect = 6e-10 Identities = 29/63 (46%), Positives = 41/63 (65%) Frame = +1 Query: 13 VEPLMVPEGVKPGDIVTVEGFNYKPDDIMNPKKKILETVKPDLKVDENGIATYRGARWQV 192 VE L P G PGD +T + F +PD +NPKKKI E ++PDL + +ATY+GA ++V Sbjct: 234 VEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNAECVATYKGAPFEV 293 Query: 193 NGQ 201 G+ Sbjct: 294 KGK 296
>sp|Q12904|MCA1_HUMAN Multisynthetase complex auxiliary component p43 [Contains: Endothelial monocyte-activating polypeptide II (EMAP-II) (Small inducible cytokine subfamily E member 1)] Length = 312 Score = 60.8 bits (146), Expect = 1e-09 Identities = 27/63 (42%), Positives = 41/63 (65%) Frame = +1 Query: 13 VEPLMVPEGVKPGDIVTVEGFNYKPDDIMNPKKKILETVKPDLKVDENGIATYRGARWQV 192 +E L P G PGD +T + F +PD +NPKKKI E ++PDL ++ +ATY+G ++V Sbjct: 236 IEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEV 295 Query: 193 NGQ 201 G+ Sbjct: 296 KGK 298
>sp|O54873|MCA1_CRIGR Multisynthetase complex auxiliary component p43 [Contains: Endothelial monocyte-activating polypeptide II (EMAP-II) (Small inducible cytokine subfamily E member 1)] Length = 359 Score = 60.5 bits (145), Expect = 1e-09 Identities = 28/63 (44%), Positives = 41/63 (65%) Frame = +1 Query: 13 VEPLMVPEGVKPGDIVTVEGFNYKPDDIMNPKKKILETVKPDLKVDENGIATYRGARWQV 192 VE L P G PGD +T + F +PD +NPKKKI E ++PDL + +ATY+G+ ++V Sbjct: 283 VEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNAECVATYKGSPFEV 342 Query: 193 NGQ 201 G+ Sbjct: 343 KGK 345
>sp|Q20970|SYM_CAEEL Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS) Length = 917 Score = 53.5 bits (127), Expect = 2e-07 Identities = 26/55 (47%), Positives = 34/55 (61%) Frame = +1 Query: 13 VEPLMVPEGVKPGDIVTVEGFNYKPDDIMNPKKKILETVKPDLKVDENGIATYRG 177 VE + VP KPG V + ++PD+ +NPKKKI ETV DLKV G A ++G Sbjct: 841 VEIMEVPADSKPGTPVVCPPYTHRPDEQLNPKKKIWETVAEDLKVSAEGFAEWKG 895
>sp|Q9SVN5|SYM_ARATH Probable methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS) Length = 797 Score = 50.4 bits (119), Expect = 1e-06 Identities = 24/54 (44%), Positives = 34/54 (62%) Frame = +1 Query: 13 VEPLMVPEGVKPGDIVTVEGFNYKPDDIMNPKKKILETVKPDLKVDENGIATYR 174 VE + P+ G+ VT GF +PDD++NPKKK+ ET+ DL EN +A Y+ Sbjct: 722 VELVEPPKTANIGERVTFPGFEGEPDDVLNPKKKVWETLLVDLNTKENLVACYK 775
>sp|P54577|SYYC_HUMAN Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS) Length = 528 Score = 47.8 bits (112), Expect = 9e-06 Identities = 27/74 (36%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = +1 Query: 13 VEPLMVPEGVKPGDIVTVEGFNY-KPDDIMNPKKKILETVKPDLKVDENGIATYRGARWQ 189 VEPL P G PG+ V V+G+ +PD+ + PKKK+ E ++ D K+ E IA ++ + Sbjct: 452 VEPLDPPAGSAPGEHVFVKGYEKGQPDEELKPKKKVFEKLQADFKISEECIAQWKQTNFM 511 Query: 190 VNGQAGAIISTKLK 231 + G+I LK Sbjct: 512 T--KLGSISCKSLK 523
>sp|Q91WQ3|SYYC_MOUSE Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS) Length = 528 Score = 47.4 bits (111), Expect = 1e-05 Identities = 23/55 (41%), Positives = 35/55 (63%), Gaps = 1/55 (1%) Frame = +1 Query: 13 VEPLMVPEGVKPGDIVTVEGFNY-KPDDIMNPKKKILETVKPDLKVDENGIATYR 174 VEPL P G PG+ V V+G+ +PD+ + PKKK+ E ++ D K+ E IA ++ Sbjct: 452 VEPLDPPAGSAPGERVFVQGYEKGQPDEELKPKKKVFEKLQADFKISEECIAQWK 506
>sp|Q29465|SYYC_BOVIN Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS) Length = 528 Score = 46.2 bits (108), Expect = 3e-05 Identities = 25/74 (33%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = +1 Query: 13 VEPLMVPEGVKPGDIVTVEGFNY-KPDDIMNPKKKILETVKPDLKVDENGIATYRGARWQ 189 VEPL P G PG+ V V+G+ +PD+ + PKKK+ E ++ D K+ + IA ++ + Sbjct: 452 VEPLDPPAGSAPGERVFVKGYEKGQPDEELKPKKKVFEKLQADFKISDEYIAQWKQTNFM 511 Query: 190 VNGQAGAIISTKLK 231 + G++ LK Sbjct: 512 T--KMGSVSCKSLK 523
>sp|P46672|G4P1_YEAST GU4 nucleic-binding protein 1 (G4p1 protein) (P42) (ARC1 protein) Length = 376 Score = 31.2 bits (69), Expect = 0.84 Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Frame = +1 Query: 13 VEPLMVPEGVKPGDIVTVEGFNYK-PDDIMNPKKKILETVKPDLKVDE 153 VEP P+ K GD V EGF + P +NPKKKI E ++P ++ Sbjct: 294 VEP---PKDSKAGDKVFFEGFGDEAPMKQLNPKKKIWEHLQPHFTTND 338
>sp|Q922D8|C1TC_MOUSE C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase ; Methenyltetrahydrofolate cyclohydrolase ; Formyltetrahydrofolate synthetase ] Length = 935 Score = 29.6 bits (65), Expect = 2.4 Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 1/42 (2%) Frame = +1 Query: 16 EPLMVP-EGVKPGDIVTVEGFNYKPDDIMNPKKKILETVKPD 138 +P MV E +KPG +V G NY PDD +K++ V D Sbjct: 218 QPEMVKGEWIKPGAVVIDCGINYVPDDTKPNGRKVVGDVAYD 259
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,074,889 Number of Sequences: 369166 Number of extensions: 620420 Number of successful extensions: 2218 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2190 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2215 length of database: 68,354,980 effective HSP length: 99 effective length of database: 50,066,215 effective search space used: 1852449955 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)