Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_J04
(511 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P37662|YHJX_ECOLI Inner membrane protein yhjX 72 8e-13
sp|Q51330|OXLT_OXAFO Oxalate:formate antiporter (OFA) (Oxal... 62 1e-09
sp|Q08268|MCH4_YEAST Probable transporter MCH4 47 3e-05
sp|P36032|MCH2_YEAST Probable transporter MCH2 46 4e-05
sp|Q96TW9|MCH1_HANAN Probable transporter MCH1 46 4e-05
sp|P53918|YNM5_YEAST Hypothetical 73.8 kDa protein in SPC98... 45 8e-05
sp|O15403|MOT7_HUMAN Monocarboxylate transporter 7 (MCT 7) ... 44 2e-04
sp|Q90632|MOT3_CHICK Monocarboxylate transporter 3 (MCT 3) ... 44 2e-04
sp|P36021|MOT8_HUMAN Monocarboxylate transporter 8 (MCT 8) ... 42 0.001
sp|O70324|MOT8_MOUSE Monocarboxylate transporter 8 (MCT 8) ... 42 0.001
>sp|P37662|YHJX_ECOLI Inner membrane protein yhjX
Length = 402
Score = 72.0 bits (175), Expect = 8e-13
Identities = 43/158 (27%), Positives = 77/158 (48%)
Frame = +3
Query: 33 GGFLIQFSLGTIYTFGNMSPYIASYLKYRTSNTWVTNGDMVWIFSLAVFSQAFTMSLGGL 212
G + QF+LG++YT+ + +++ L S + + F L A + S+ G
Sbjct: 16 GTIITQFALGSVYTWSLFNGALSAKLDAPVSQ-------VAFSFGLLSLGLAISSSVAGK 68
Query: 213 LEKKIGPRLTCWIGGWTMSVGTILTYFTIQYNLWTVILTYGFIFGAGTGLTYSVAIATPM 392
L+++ G + G + +G LT + NL + L+ G + G G Y + ++ +
Sbjct: 69 LQERFGVKRVTMASGILLGLGFFLTAHSD--NLMMLWLSAGVLVGLADGAGYLLTLSNCV 126
Query: 393 KWFPLHRGLVAGSVVAGYGLGSLLFNIIQTQYINPLNI 506
KWFP +GL++ + YGLGSL F I TQ + + +
Sbjct: 127 KWFPERKGLISAFAIGSYGLGSLGFKFIDTQLLETVGL 164
>sp|Q51330|OXLT_OXAFO Oxalate:formate antiporter (OFA) (Oxalate:formate antiport protein)
(Oxalate:formate exchange protein)
Length = 418
Score = 61.6 bits (148), Expect = 1e-09
Identities = 41/112 (36%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Frame = +3
Query: 165 SLAVFSQAFTMSL---------GGLLEKKIGPRLTCWIGGWTMSVGTILTYFTIQYNLWT 317
SLA AFT+S GG K GPR+ GG +L +T + +
Sbjct: 51 SLAAVQTAFTLSQVIQAGSQPGGGYFVDKFGPRIPLMFGG-----AMVLAGWTFMGMVDS 105
Query: 318 VILTYGF--IFGAGTGLTYSVAIATPMKWFPLHRGLVAGSVVAGYGLGSLLF 467
V Y + GAG G+ Y +A+ T +WFP RGL +G AGYGLG L F
Sbjct: 106 VPALYALYTLAGAGVGIVYGIAMNTANRWFPDKRGLASGFTAAGYGLGVLPF 157
>sp|Q08268|MCH4_YEAST Probable transporter MCH4
Length = 501
Score = 46.6 bits (109), Expect = 3e-05
Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 1/140 (0%)
Frame = +3
Query: 60 GTIYTFGNMSPYIASYLKYRTSNTWVTNGDMVWIFSLAVFSQAFTMSL-GGLLEKKIGPR 236
G I + G + YI+ K++ +N +++ + WIFSL + + L GG ++
Sbjct: 112 GLINSLGAIESYIS---KHQLAN--ISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIG 166
Query: 237 LTCWIGGWTMSVGTILTYFTIQYNLWTVILTYGFIFGAGTGLTYSVAIATPMKWFPLHRG 416
L C G + G + + ++W IL + G GTG+ + I T WF RG
Sbjct: 167 LMCT--GTVIYAGGLFALANCK-SVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRG 223
Query: 417 LVAGSVVAGYGLGSLLFNII 476
+ G +G ++F I+
Sbjct: 224 IATSISTMGGSIGGIVFPIM 243
>sp|P36032|MCH2_YEAST Probable transporter MCH2
Length = 473
Score = 46.2 bits (108), Expect = 4e-05
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 2/146 (1%)
Frame = +3
Query: 42 LIQFSLGTIYTFGNMSPYIASYLKYRTSNTWVTNG--DMVWIFSLAVFSQAFTMSLGGLL 215
L+ F L T+G S Y Y +NT+ D I LA F + L
Sbjct: 45 LLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWL 104
Query: 216 EKKIGPRLTCWIGGWTMSVGTILTYFTIQYNLWTVILTYGFIFGAGTGLTYSVAIATPMK 395
+ +G +L F++ LW + LT G + G G + ++
Sbjct: 105 YHIFSIQFIIGLGILFQGAALLLAAFSV--TLWEIYLTQGVLIGFGLAFIFIPSVTLIPL 162
Query: 396 WFPLHRGLVAGSVVAGYGLGSLLFNI 473
WF R L +G AG GLG ++FN+
Sbjct: 163 WFRNKRSLASGIGTAGSGLGGIVFNL 188
>sp|Q96TW9|MCH1_HANAN Probable transporter MCH1
Length = 489
Score = 46.2 bits (108), Expect = 4e-05
Identities = 42/151 (27%), Positives = 62/151 (41%), Gaps = 2/151 (1%)
Frame = +3
Query: 18 ISCVCGGFLIQFSLGTIYTFGNMSPYIASYLKYRTSNTWVTNGDMVWIFSLAVFSQAFTM 197
ISC+C G ++ F+L T P + L Y T + I S +
Sbjct: 37 ISCLCAGSVLLFALFT--------PVLQHQLHY-------TQFQINIIGSFTSIGMYLPL 81
Query: 198 SLGGLLEKKIGPRLTCWIGGWTMSVGTILTYFTIQ--YNLWTVILTYGFIFGAGTGLTYS 371
+ G L GP L I S G L +Q ++ W + +++G I G T Y
Sbjct: 82 PVLGYLADCHGPVLLSVISVLFFSPGYTLAATVVQNDWSFWYLAISFGLI-GCATSALYF 140
Query: 372 VAIATPMKWFPLHRGLVAGSVVAGYGLGSLL 464
A+ T K +P +GL + V YGL SL+
Sbjct: 141 TALLTCAKIYPKSKGLTISAPVTCYGLSSLI 171
>sp|P53918|YNM5_YEAST Hypothetical 73.8 kDa protein in SPC98-TOM70 intergenic region
Length = 673
Score = 45.4 bits (106), Expect = 8e-05
Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 1/153 (0%)
Frame = +3
Query: 39 FLIQFSL-GTIYTFGNMSPYIASYLKYRTSNTWVTNGDMVWIFSLAVFSQAFTMSLGGLL 215
FL FS G +FG Y ++ Y ++ + D I L VF L L
Sbjct: 220 FLTMFSTWGCNASFGVDLAYYLNHDTYPGASKY----DYALIAGLTVFLGQLLSPLVMAL 275
Query: 216 EKKIGPRLTCWIGGWTMSVGTILTYFTIQYNLWTVILTYGFIFGAGTGLTYSVAIATPMK 395
+ IG R T G M +L FT + LW + +T GF+ G L + A
Sbjct: 276 MRIIGLRTTMLFGDAVMLAAYLLASFTTK--LWQLYVTQGFMVGCSISLIFVPATTVLPG 333
Query: 396 WFPLHRGLVAGSVVAGYGLGSLLFNIIQTQYIN 494
WF R + G + G G G +++ + + ++
Sbjct: 334 WFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLS 366
>sp|O15403|MOT7_HUMAN Monocarboxylate transporter 7 (MCT 7) (MCT 6)
Length = 523
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/135 (25%), Positives = 58/135 (42%)
Frame = +3
Query: 39 FLIQFSLGTIYTFGNMSPYIASYLKYRTSNTWVTNGDMVWIFSLAVFSQAFTMSLGGLLE 218
F+ F+ G I TFG + + SN+ ++ WI S+ VF F+ L +L
Sbjct: 33 FVEVFTYGIIKTFGVFFNDLMD--SFNESNSRIS-----WIISICVFVLTFSAPLATVLS 85
Query: 219 KKIGPRLTCWIGGWTMSVGTILTYFTIQYNLWTVILTYGFIFGAGTGLTYSVAIATPMKW 398
+ G RL +GG +S G + F+ + + V + G I G G ++ + ++
Sbjct: 86 NRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAI--GIISGLGYCFSFLPTVTILSQY 143
Query: 399 FPLHRGLVAGSVVAG 443
F R +V G
Sbjct: 144 FGKRRSIVTAVASTG 158
>sp|Q90632|MOT3_CHICK Monocarboxylate transporter 3 (MCT 3) (Retinal epithelial membrane
protein)
Length = 542
Score = 43.9 bits (102), Expect = 2e-04
Identities = 38/137 (27%), Positives = 55/137 (40%), Gaps = 1/137 (0%)
Frame = +3
Query: 36 GFLIQFSLGTIYTFGNMSPYIAS-YLKYRTSNTWVTNGDMVWIFSLAVFSQAFTMSLGGL 212
G+++ F I F P S Y K + V D WI S+ + T + +
Sbjct: 23 GWIVLFGCFVITGFSYAFPKAVSVYFKELMKDFHVGYSDTAWISSIMLAMLYGTGPVCSI 82
Query: 213 LEKKIGPRLTCWIGGWTMSVGTILTYFTIQYNLWTVILTYGFIFGAGTGLTYSVAIATPM 392
+ + G R IGG S G IL FT N+ + LT G + G G L + ++
Sbjct: 83 MVNQFGCRPVMLIGGLLASSGMILASFTT--NIIELYLTAGVLTGLGMALNFQPSLIMLG 140
Query: 393 KWFPLHRGLVAGSVVAG 443
+F R L G AG
Sbjct: 141 TYFDKRRPLANGLAAAG 157
>sp|P36021|MOT8_HUMAN Monocarboxylate transporter 8 (MCT 8) (X-linked PEST-containing
transporter) (MCT 7)
Length = 613
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/104 (25%), Positives = 45/104 (43%)
Frame = +3
Query: 156 WIFSLAVFSQAFTMSLGGLLEKKIGPRLTCWIGGWTMSVGTILTYFTIQYNLWTVILTYG 335
W+ +LA+ F + + ++G R+T G +G + FT +L TYG
Sbjct: 219 WVGALAMGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLR--YFTYG 276
Query: 336 FIFGAGTGLTYSVAIATPMKWFPLHRGLVAGSVVAGYGLGSLLF 467
+FG G + ++ +F GL G V AG + S+ F
Sbjct: 277 ILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSF 320
>sp|O70324|MOT8_MOUSE Monocarboxylate transporter 8 (MCT 8) (X-linked PEST-containing
transporter)
Length = 565
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/104 (25%), Positives = 45/104 (43%)
Frame = +3
Query: 156 WIFSLAVFSQAFTMSLGGLLEKKIGPRLTCWIGGWTMSVGTILTYFTIQYNLWTVILTYG 335
W+ +LA+ F + + ++G R+T G +G + FT +L TYG
Sbjct: 171 WVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLR--YFTYG 228
Query: 336 FIFGAGTGLTYSVAIATPMKWFPLHRGLVAGSVVAGYGLGSLLF 467
+FG G + ++ +F GL G V AG + S+ F
Sbjct: 229 ILFGCGCSFAFQPSLVILDHYFQRRLGLANGVVSAGSSIFSMSF 272
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,327,463
Number of Sequences: 369166
Number of extensions: 1247888
Number of successful extensions: 3577
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3481
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3568
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3255600150
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)