Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_I21
(466 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P70191|TRAF5_MOUSE TNF receptor-associated factor 5 50 3e-06
sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD4... 49 6e-06
sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD4... 49 6e-06
sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RIN... 48 9e-06
sp|P39429|TRAF2_MOUSE TNF receptor-associated factor 2 43 3e-04
sp|P28826|MEP1B_RAT Meprin A beta-subunit precursor (Endope... 43 3e-04
sp|Q61847|MEP1B_MOUSE Meprin A beta-subunit precursor (Endo... 43 4e-04
sp|P39428|TRAF1_MOUSE TNF receptor-associated factor 1 42 5e-04
sp|Q16820|MEP1B_HUMAN Meprin A beta-subunit precursor (Endo... 42 5e-04
sp|Q12933|TRAF2_HUMAN TNF receptor-associated factor 2 (Tum... 42 7e-04
>sp|P70191|TRAF5_MOUSE TNF receptor-associated factor 5
Length = 558
Score = 49.7 bits (117), Expect = 3e-06
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Frame = +1
Query: 16 LFSIPFYSHSKGYKMCLRLDRGGLCSG----FSIHFHIMKGDFDNELQWPMPYEILIGFR 183
+FS PFY+ GY++C R G SG S++F +M+G+FD+ LQWP + +
Sbjct: 428 VFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLL 487
Query: 184 HPKTGTWRLIKKFIYKSIEEENKFKFLKPTDKMNSSCG 297
+++ F + N F +P +MN + G
Sbjct: 488 DQSGKKNHIVETF----KADPNSSSFKRPDGEMNIASG 521
>sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD40 receptor associated factor
1) (CRAF1) (CD40 binding protein) (CD40BP) (LMP1
associated protein) (LAP1) (CAP-1)
Length = 568
Score = 48.9 bits (115), Expect = 6e-06
Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
Frame = +1
Query: 16 LFSIPFYSHSKGYKMCLRL----DRGGLCSGFSIHFHIMKGDFDNELQWPMPYEILIGFR 183
L+S PFY+ GYKMC R+ D G + S+ F IM+G++D L WP ++ +
Sbjct: 440 LYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLM 499
Query: 184 HPKTGTWRLIKKFIYKSIEEENKFKFLKPTDKMNSSCG 297
+ L F + N F KPT +MN + G
Sbjct: 500 DQGSSRRHLGDAF----KPDPNSSSFKKPTGEMNIASG 533
>sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD40 receptor associated factor
1) (CRAF1) (TRAFAMN)
Length = 567
Score = 48.9 bits (115), Expect = 6e-06
Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
Frame = +1
Query: 16 LFSIPFYSHSKGYKMCLRL----DRGGLCSGFSIHFHIMKGDFDNELQWPMPYEILIGFR 183
L+S PFY+ GYKMC R+ D G + S+ F IM+G++D L WP ++ +
Sbjct: 439 LYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLM 498
Query: 184 HPKTGTWRLIKKFIYKSIEEENKFKFLKPTDKMNSSCG 297
+ L F + N F KPT +MN + G
Sbjct: 499 DQGSSRRHLGDAF----KPDPNSSSFKKPTGEMNIASG 532
>sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RING finger protein 84)
Length = 557
Score = 48.1 bits (113), Expect = 9e-06
Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 4/98 (4%)
Frame = +1
Query: 16 LFSIPFYSHSKGYKMCLRL----DRGGLCSGFSIHFHIMKGDFDNELQWPMPYEILIGFR 183
+FS FY+ GY++C R D G S S++F +M+G+FD+ LQWP + +
Sbjct: 428 IFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTL-ML 486
Query: 184 HPKTGTWRLIKKFIYKSIEEENKFKFLKPTDKMNSSCG 297
++G +++ F + N F +P +MN + G
Sbjct: 487 LDQSGKKNIMETF----KPDPNSSSFKRPDGEMNIASG 520
>sp|P39429|TRAF2_MOUSE TNF receptor-associated factor 2
Length = 501
Score = 43.1 bits (100), Expect = 3e-04
Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 4/57 (7%)
Frame = +1
Query: 16 LFSIPFYSHSKGYKMCLRL----DRGGLCSGFSIHFHIMKGDFDNELQWPMPYEILI 174
+FS FY+ GYKMCLR+ D G + S+ F +MKG D LQWP ++ +
Sbjct: 376 IFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTL 432
>sp|P28826|MEP1B_RAT Meprin A beta-subunit precursor (Endopeptidase-2)
Length = 704
Score = 43.1 bits (100), Expect = 3e-04
Identities = 21/52 (40%), Positives = 33/52 (63%)
Frame = +1
Query: 10 TRLFSIPFYSHSKGYKMCLRLDRGGLCSGFSIHFHIMKGDFDNELQWPMPYE 165
T ++S PFYS SKGY + LD + ++FH++ G D++LQWP P++
Sbjct: 446 TTVYSPPFYS-SKGYAFQINLDLTSP-TNVGLYFHLISGANDDQLQWPCPWQ 495
>sp|Q61847|MEP1B_MOUSE Meprin A beta-subunit precursor (Endopeptidase-2)
Length = 704
Score = 42.7 bits (99), Expect = 4e-04
Identities = 21/52 (40%), Positives = 33/52 (63%)
Frame = +1
Query: 10 TRLFSIPFYSHSKGYKMCLRLDRGGLCSGFSIHFHIMKGDFDNELQWPMPYE 165
T ++S PFYS SKGY + +D + I+FH++ G D++LQWP P++
Sbjct: 447 TSVYSPPFYS-SKGYAFQIYMDLR-YSTNVGIYFHLISGANDDQLQWPCPWQ 496
>sp|P39428|TRAF1_MOUSE TNF receptor-associated factor 1
Length = 409
Score = 42.4 bits (98), Expect = 5e-04
Identities = 23/50 (46%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Frame = +1
Query: 16 LFSIPFYSHSKGYKMCLRLDRGGLCSGFSIHFH----IMKGDFDNELQWP 153
LFS FY+ GYK+CLRL G SG H IM+G++D L WP
Sbjct: 284 LFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWP 333
>sp|Q16820|MEP1B_HUMAN Meprin A beta-subunit precursor (Endopeptidase-2)
(N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase beta
subunit) (PABA peptide hydrolase) (PPH beta)
Length = 701
Score = 42.4 bits (98), Expect = 5e-04
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +1
Query: 16 LFSIPFYSHSKGYKMCLRLDRGGLCSGFSIHFHIMKGDFDNELQWPMPYE 165
L+S PFYS SKGY + L+ + + I+FH++ G D++LQWP P++
Sbjct: 448 LYSPPFYS-SKGYAFQIYLNLAHVTNA-GIYFHLISGANDDQLQWPCPWQ 495
>sp|Q12933|TRAF2_HUMAN TNF receptor-associated factor 2 (Tumor necrosis factor type 2
receptor-associated protein 3)
Length = 501
Score = 42.0 bits (97), Expect = 7e-04
Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 4/57 (7%)
Frame = +1
Query: 16 LFSIPFYSHSKGYKMCLRL----DRGGLCSGFSIHFHIMKGDFDNELQWPMPYEILI 174
+FS FY+ GYKMCLR+ D G + S+ F +MKG D L+WP ++ +
Sbjct: 376 IFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTL 432
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,064,895
Number of Sequences: 369166
Number of extensions: 1040090
Number of successful extensions: 2045
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2014
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2031
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2633927485
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)