Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_H16-1
(154 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P30432|FUR2_DROME Furin-like protease 2 precursor (Furin-2) 48 8e-06
sp|P29122|PCSK6_HUMAN Proprotein convertase subtilisin/kexi... 44 9e-05
sp|Q04592|PCSK5_MOUSE Proprotein convertase subtilisin/kexi... 44 2e-04
sp|Q9NJ15|PCSK5_BRACL Proprotein convertase subtilisin/kexi... 43 2e-04
sp|Q92824|PCSK5_HUMAN Proprotein convertase subtilisin/kexi... 42 4e-04
sp|Q86XX4|FRAS1_HUMAN Extracellular matrix protein FRAS1 pr... 41 8e-04
sp|P29119|FURI1_XENLA Furin-1 precursor (Paired basic amino... 39 0.003
sp|Q80T14|FRAS1_MOUSE Extracellular matrix protein FRAS1 pr... 39 0.005
sp|Q63415|PCSK6_RAT Proprotein convertase subtilisin/kexin ... 38 0.006
sp|P41413|PCSK5_RAT Proprotein convertase subtilisin/kexin ... 38 0.008
>sp|P30432|FUR2_DROME Furin-like protease 2 precursor (Furin-2)
Length = 1679
Score = 47.8 bits (112), Expect = 8e-06
Identities = 17/41 (41%), Positives = 26/41 (63%)
Frame = +1
Query: 13 CTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHI 135
C + QY++TT+ TC+ CH +C SC G G +C C+ H+
Sbjct: 1386 CLSSQYYDTTSATCKTCHDSCRSCFGPGQFSCKGCVPPLHL 1426
Score = 42.7 bits (99), Expect = 3e-04
Identities = 12/38 (31%), Positives = 24/38 (63%)
Frame = +1
Query: 4 NQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
++ C+ ++++ C+ CH +CGSC G D +C++C
Sbjct: 1195 SEGCSESEFYSQVEGQCRPCHASCGSCNGPADTSCTSC 1232
Score = 37.7 bits (86), Expect = 0.008
Identities = 16/39 (41%), Positives = 18/39 (46%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C Y T C CH TC +C G DQ+C TC
Sbjct: 1094 CYSACPLDTY-ETEDNKCAFCHSTCATCNGPTDQDCITC 1131
Score = 37.0 bits (84), Expect = 0.014
Identities = 15/42 (35%), Positives = 22/42 (52%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQH 126
C Q C G + N+ +TC C C SCQ + + C++C H
Sbjct: 1046 CLQFCPDGYFENSRNRTCVPCEPNCASCQDH-PEYCTSCDHH 1086
Score = 35.8 bits (81), Expect = 0.032
Identities = 16/43 (37%), Positives = 21/43 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHS 129
C+ C G Y + CQKCH C +C G C++C HS
Sbjct: 1336 CHPECPEGFY--KSDFGCQKCHHYCKTCNDAGPLACTSCPPHS 1376
Score = 34.3 bits (77), Expect = 0.093
Identities = 13/30 (43%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Frame = +1
Query: 52 CQKCHITCGSCQGNGDQNCSTCI-QHSHIL 138
C CH TC +C G G +C TC H H++
Sbjct: 1012 CWPCHDTCETCAGAGPDSCLTCAPAHLHVI 1041
Score = 31.6 bits (70), Expect = 0.60
Identities = 12/39 (30%), Positives = 17/39 (43%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C G Y + C KC+++C +C G C C
Sbjct: 1289 CRTTCADGYY--SDRGICAKCYLSCHTCSGPRRNQCVQC 1325
>sp|P29122|PCSK6_HUMAN Proprotein convertase subtilisin/kexin type 6 precursor (Paired
basic amino acid cleaving enzyme 4)
(Subtilisin/kexin-like protease PACE4) (Subtilisin-like
proprotein convertase 4) (SPC4)
Length = 969
Score = 44.3 bits (103), Expect = 9e-05
Identities = 16/44 (36%), Positives = 25/44 (56%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSH 132
C +C G Y+++ C +CH TCG+C G G + C C ++ H
Sbjct: 828 CIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFH 871
Score = 34.7 bits (78), Expect = 0.071
Identities = 11/39 (28%), Positives = 18/39 (46%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C G + +T + C++CH C +C C +C
Sbjct: 729 CVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQCLSC 767
Score = 31.6 bits (70), Expect = 0.60
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C G Y + + K C KCH +C C + + C+ C
Sbjct: 780 CVTLCPAGFYADESQKNCLKCHPSCKKCV-DEPEKCTVC 817
Score = 28.5 bits (62), Expect = 5.1
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +1
Query: 46 KTCQKCHITCGSCQGNGDQNCSTC 117
K C++C C SC G+ +NCS C
Sbjct: 896 KVCRRCDENCLSCAGS-SRNCSRC 918
>sp|Q04592|PCSK5_MOUSE Proprotein convertase subtilisin/kexin type 5 precursor (Proprotein
convertase PC5) (Subtilisin/kexin-like protease PC5)
(PC6) (Subtilisin-like proprotein convertase 6) (SPC6)
Length = 1877
Score = 43.5 bits (101), Expect = 2e-04
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSH 132
C NC + ++ K C CH TC CQG+G NC++C H
Sbjct: 919 CVMNCPSWKF--EFKKQCHPCHYTCQGCQGSGPSNCTSCRADKH 960
Score = 43.1 bits (100), Expect = 2e-04
Identities = 15/46 (32%), Positives = 25/46 (54%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHIL 138
C++ C Y + +TC++CH TC C G +C +C+ H+L
Sbjct: 1626 CHRACPEHYYADQHAQTCERCHPTCDKCSGKEAWSCLSCVWSYHLL 1671
Score = 42.4 bits (98), Expect = 3e-04
Identities = 14/44 (31%), Positives = 22/44 (50%)
Frame = +1
Query: 7 QNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHIL 138
+ C +YW+ + CQ CH C C G + C TC + + +L
Sbjct: 1479 KECAAVEYWDEGSHRCQPCHKKCSRCSGPSEDQCYTCpreTFLL 1522
Score = 38.5 bits (88), Expect = 0.005
Identities = 15/41 (36%), Positives = 20/41 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQ 123
C+ C GQ++N CQ CH C +C G G C C +
Sbjct: 769 CSVTCEDGQFFNG--HDCQPCHRFCATCSGAGADGCINCTE 807
Score = 38.5 bits (88), Expect = 0.005
Identities = 15/43 (34%), Positives = 27/43 (62%), Gaps = 4/43 (9%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTT----KTCQKCHITCGSCQGNGDQNCSTC 117
C Q+C+ Y + ++ K+C++C +C +C G G +NCS+C
Sbjct: 816 CVQSCSVSYYLDHSSEGGYKSCKRCDNSCLTCNGPGFKNCSSC 858
Score = 38.5 bits (88), Expect = 0.005
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C Q+C G + + C+ CH C +C G+G CS+C
Sbjct: 1113 CVQDCGPGFHGDQELGECKPCHRACETCTGSGYNQCSSC 1151
Score = 38.5 bits (88), Expect = 0.005
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C G Y +T+ C+KC +C SC+G +C +C
Sbjct: 1575 CLLQCRDGYYGESTSGRCEKCDKSCKSCRGPRPTDCQSC 1613
Score = 38.5 bits (88), Expect = 0.005
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKT--CQKCHITCGSCQGNGDQNCSTC 117
C C G+Y + C+KCH +C C+G G +NC+ C
Sbjct: 1675 CIPECIVGEYREGKGENFNCKKCHESCMECKGPGSKNCTGC 1715
Score = 34.7 bits (78), Expect = 0.071
Identities = 11/39 (28%), Positives = 20/39 (51%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C + C G + + ++ C CH +C +C+G C +C
Sbjct: 1526 CVKECPEGYHTDKDSQQCVLCHSSCRTCEGPHSMQCLSC 1564
Score = 33.5 bits (75), Expect = 0.16
Identities = 14/39 (35%), Positives = 19/39 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C +C G Y + K C+KC C SC G+ C +C
Sbjct: 672 CVSSCPPGHY-HADKKRCRKCAPNCESCFGSHGDQCLSC 709
Score = 31.2 bits (69), Expect = 0.79
Identities = 13/40 (32%), Positives = 21/40 (52%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCI 120
C +C G + + T+ +C+KC C SC +G C C+
Sbjct: 1238 CVPSCPQGTWPSVTSGSCEKCSEDCVSC--SGADLCQQCL 1275
Score = 30.8 bits (68), Expect = 1.0
Identities = 13/46 (28%), Positives = 19/46 (41%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHIL 138
C+++C Y + C CH C C G + +C C S L
Sbjct: 1380 CHRSCPKSFY--PDMRQCVPCHKNCLECNGPKEDDCKVCADTSKAL 1423
Score = 29.6 bits (65), Expect = 2.3
Identities = 13/39 (33%), Positives = 16/39 (41%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C G Y + C KC C +C G NC+ C
Sbjct: 722 CVTQCPDGSYEDIKKNVCGKCSENCKAC--IGFHNCTEC 758
Score = 28.9 bits (63), Expect = 3.9
Identities = 11/35 (31%), Positives = 17/35 (48%)
Frame = +1
Query: 13 CTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C G+Y + CQ C +C C G ++C +C
Sbjct: 875 CKDGEYIDDQGH-CQTCEASCAKCWGPTQEDCISC 908
>sp|Q9NJ15|PCSK5_BRACL Proprotein convertase subtilisin/kexin type 5 precursor (Proprotein
convertase PC6-like) (aPC6)
Length = 1696
Score = 43.1 bits (100), Expect = 2e-04
Identities = 17/42 (40%), Positives = 23/42 (54%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQH 126
C ++C++G + C KCH TC SC G+ D C TC H
Sbjct: 809 CVESCSSGYFQQEYE--CLKCHATCASCSGSRDDQCLTCSGH 848
Score = 40.8 bits (94), Expect = 0.001
Identities = 17/49 (34%), Positives = 24/49 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHILLSD 147
C +C G+Y + K C+ CH TC C D C+ C + LL+D
Sbjct: 1268 CITSCGPGEYMDRREKKCKACHPTCKECSDEYDDTCTAC--NDGFLLTD 1314
Score = 38.9 bits (89), Expect = 0.004
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = +1
Query: 10 NCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
NC + Y + + C+ CH C +C G +QNC++C
Sbjct: 1052 NCPSFTYPDDQDRECRPCHDNCEACDGPNNQNCNSC 1087
Score = 38.9 bits (89), Expect = 0.004
Identities = 14/46 (30%), Positives = 23/46 (50%), Gaps = 7/46 (15%)
Frame = +1
Query: 1 CNQNCTTGQYWNT-------TTKTCQKCHITCGSCQGNGDQNCSTC 117
C+ +C G + T T C+ CH+ C +C G G+++C C
Sbjct: 1365 CSTHCPEGTFEETYEDDSGETVLQCRLCHVNCKTCHGEGEEDCMEC 1410
Score = 38.1 bits (87), Expect = 0.006
Identities = 11/44 (25%), Positives = 24/44 (54%)
Frame = +1
Query: 7 QNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHIL 138
+ C G Y++ + + C+ CH +C +C G C +C + ++ +
Sbjct: 662 EECEDGDYYDRSKQRCRHCHDSCATCHGRHSGQCLSCHEGNYFV 705
Score = 36.6 bits (83), Expect = 0.019
Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTT--KTCQKCHITCGSCQGNGDQNCSTC 117
C ++C G Y++T K C +CH +C +C G+ NC +C
Sbjct: 1470 CLEDCPEG-YYDTMRQEKECGECHPSCATCNEGGNYNCLSC 1509
Score = 35.8 bits (81), Expect = 0.032
Identities = 13/41 (31%), Positives = 22/41 (53%), Gaps = 4/41 (9%)
Frame = +1
Query: 7 QNCTTGQYWN----TTTKTCQKCHITCGSCQGNGDQNCSTC 117
+ C G+Y + T +C+ CH +C +C G D +C +C
Sbjct: 1216 ETCEDGEYQDRDRDTAELSCRPCHQSCKTCSGPSDTDCDSC 1256
Score = 35.0 bits (79), Expect = 0.054
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHILL 141
C C G Y + T + CQ+C C +C G + C TC + +++L
Sbjct: 1422 CVTECQEGHYPDLTNE-CQQCWSDCETCDGPRNDQCVTCPYNYYLVL 1467
Score = 34.7 bits (78), Expect = 0.071
Identities = 12/39 (30%), Positives = 19/39 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C+ C Y + T K C+ C +C +C G +C +C
Sbjct: 1098 CSTGCPNRYYKDDTNKECKPCDSSCFTCSGPASFHCLSC 1136
Score = 34.3 bits (77), Expect = 0.093
Identities = 11/39 (28%), Positives = 22/39 (56%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C +Y+ T+ C++C +C +C+G+ +C +C
Sbjct: 1520 CYPMCEEHEYYVEKTQICEECDNSCKTCRGSTAHDCLSC 1558
Score = 33.5 bits (75), Expect = 0.16
Identities = 12/36 (33%), Positives = 20/36 (55%)
Frame = +1
Query: 10 NCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
+C QY+++ T C+ C C +C +GD C+ C
Sbjct: 1168 SCEQDQYYSSETGRCEDCPYNCRACDNDGD--CAEC 1201
Score = 33.5 bits (75), Expect = 0.16
Identities = 14/45 (31%), Positives = 20/45 (44%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHI 135
C C GQ+ + C CH C +C G NC +C S++
Sbjct: 1318 CEAGCPPGQFLHHGD--CDSCHRECKTCDGPHHDNCLSCQPGSYL 1360
Score = 32.7 bits (73), Expect = 0.27
Identities = 13/39 (33%), Positives = 18/39 (46%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C +C G+Y T C+ C+I C C G+ C C
Sbjct: 858 CITSCEDGEY-GTEEGKCEDCNIICKKCNGSQADQCLEC 895
Score = 32.3 bits (72), Expect = 0.35
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C+ G+Y + CQ C +C +C G +C TC
Sbjct: 761 CVAQCSEGRYMDEND-VCQDCDDSCDTCTGPDATDCVTC 798
Score = 32.0 bits (71), Expect = 0.46
Identities = 12/39 (30%), Positives = 21/39 (53%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C++ C G Y + + C C C +CQ + D +C++C
Sbjct: 711 CSEECGQGYYKDEEERKCLDCSADCLTCQVSAD-HCTSC 748
Score = 28.1 bits (61), Expect = 6.7
Identities = 13/40 (32%), Positives = 16/40 (40%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCI 120
C Q C +Y C CH +C C G C+ CI
Sbjct: 906 CVQYCGNRRY--PENGECHPCHPSCLGCIGGEINQCNQCI 943
>sp|Q92824|PCSK5_HUMAN Proprotein convertase subtilisin/kexin type 5 precursor (Proprotein
convertase PC5) (Subtilisin/kexin-like protease PC5)
(PC6) (hPC6)
Length = 913
Score = 42.0 bits (97), Expect = 4e-04
Identities = 16/43 (37%), Positives = 29/43 (67%), Gaps = 4/43 (9%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTT----KTCQKCHITCGSCQGNGDQNCSTC 117
C Q+C+ Y++ ++ K+C+KC I+C +C G G +NC++C
Sbjct: 814 CVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSC 856
Score = 39.3 bits (90), Expect = 0.003
Identities = 15/41 (36%), Positives = 22/41 (53%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQ 123
C+ +C G+Y+N + CQ CH C +C G G C C +
Sbjct: 767 CSVSCEDGRYFNG--QDCQPCHRFCATCAGAGADGCINCTE 805
Score = 33.9 bits (76), Expect = 0.12
Identities = 14/39 (35%), Positives = 19/39 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C +C G Y + K C+KC C SC G+ C +C
Sbjct: 670 CVSSCPPGHY-HADKKRCRKCAPNCESCFGSHGDQCMSC 707
Score = 31.6 bits (70), Expect = 0.60
Identities = 13/39 (33%), Positives = 18/39 (46%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C +C G Y +T C+KC C +C NC+ C
Sbjct: 720 CVTHCPDGSYQDTKKNLCRKCSENCKTC--TEFHNCTEC 756
>sp|Q86XX4|FRAS1_HUMAN Extracellular matrix protein FRAS1 precursor
Length = 4007
Score = 41.2 bits (95), Expect = 8e-04
Identities = 16/39 (41%), Positives = 23/39 (58%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C +C +G Y C+KCH +C +CQG G +CS+C
Sbjct: 842 CVPDCPSGYY--AERGACKKCHSSCRTCQGRGPFSCSSC 878
Score = 36.2 bits (82), Expect = 0.024
Identities = 14/39 (35%), Positives = 20/39 (51%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C G Y + T + C+ CH +C SC G +C+ C
Sbjct: 589 CMSECPGGYYADATGR-CKVCHNSCASCSGPTPSHCTAC 626
Score = 35.0 bits (79), Expect = 0.054
Identities = 16/47 (34%), Positives = 23/47 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHILL 141
C C ++ +T C+ CH +C C G NC+ C SH+LL
Sbjct: 695 CLAQCRA-HFYLESTGLCEACHQSCFRCAGKSPHNCTDC-GPSHVLL 739
Score = 33.5 bits (75), Expect = 0.16
Identities = 15/47 (31%), Positives = 24/47 (51%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHILL 141
C+ C G Y + CQ C+ CGSC + +C++C + +LL
Sbjct: 890 CSTTCFPGHYLDDN-HVCQPCNTHCGSC--DSQASCTSCRDPNKVLL 933
Score = 33.1 bits (74), Expect = 0.21
Identities = 13/42 (30%), Positives = 19/42 (45%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQH 126
C C G + + C +CH TC C G + +C +C H
Sbjct: 743 CLSQCPDGYFHQEGS--CTECHPTCRQCHGPLESDCISCYPH 782
Score = 33.1 bits (74), Expect = 0.21
Identities = 11/38 (28%), Positives = 21/38 (55%)
Frame = +1
Query: 7 QNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCI 120
++C Y + +T TC++C +C +C G +C C+
Sbjct: 940 ESCAPQYYLDFSTNTCKECDWSCSACSGPLKTDCLQCM 977
Score = 32.7 bits (73), Expect = 0.27
Identities = 14/46 (30%), Positives = 21/46 (45%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHIL 138
C C G Y + +C CH +C C G +++C C H+L
Sbjct: 495 CVPTCGDGFYQDR--HSCAVCHESCAGCWGPTEKHCLACRDPLHVL 538
Score = 29.6 bits (65), Expect = 2.3
Identities = 12/39 (30%), Positives = 18/39 (46%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C G Y + C+ CH +C +C G +C+ C
Sbjct: 637 CLPRCGEGFY--SDHGVCKACHSSCLACMGPAPSHCTGC 673
>sp|P29119|FURI1_XENLA Furin-1 precursor (Paired basic amino acid residue cleaving enzyme)
(PACE) (Dibasic processing enzyme)
Length = 783
Score = 39.3 bits (90), Expect = 0.003
Identities = 14/32 (43%), Positives = 19/32 (59%)
Frame = +1
Query: 52 CQKCHITCGSCQGNGDQNCSTCIQHSHILLSD 147
C CH++C +C+G +C TC HSH L D
Sbjct: 639 CVPCHVSCATCKGTTINDCLTCPAHSHYNLLD 670
>sp|Q80T14|FRAS1_MOUSE Extracellular matrix protein FRAS1 precursor
Length = 4010
Score = 38.5 bits (88), Expect = 0.005
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C G Y TC+ CH +C SCQ G +CS+C
Sbjct: 841 CVPECPPGHY--KERGTCKTCHSSCRSCQNGGPFSCSSC 877
Score = 37.4 bits (85), Expect = 0.011
Identities = 16/48 (33%), Positives = 27/48 (56%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHILLS 144
C C T ++ +T C+ CH +C +C+G NC+ C + +H LL+
Sbjct: 694 CVSRCGT-HFYLESTGLCEVCHPSCLTCEGKSPHNCTGC-ESTHALLA 739
Score = 36.6 bits (83), Expect = 0.019
Identities = 15/40 (37%), Positives = 21/40 (52%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCI 120
C C G Y+ +T +C+ CH +C SC G +C CI
Sbjct: 588 CISECPHG-YYADSTGSCKVCHSSCASCSGPTAAHCIACI 626
Score = 36.2 bits (82), Expect = 0.024
Identities = 13/38 (34%), Positives = 22/38 (57%)
Frame = +1
Query: 7 QNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCI 120
++CT Y + TKTC++C +C +C G +C C+
Sbjct: 939 ESCTPQYYLDIATKTCKECDWSCNACTGPLRTDCLQCM 976
Score = 33.1 bits (74), Expect = 0.21
Identities = 16/47 (34%), Positives = 24/47 (51%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSHILL 141
C+ C G Y + + CQ C+ C SC G +C++C S +LL
Sbjct: 889 CSTACFPGHYLDDN-QVCQPCNRHCRSCDSQG--SCTSCRDPSKVLL 932
Score = 32.7 bits (73), Expect = 0.27
Identities = 12/32 (37%), Positives = 19/32 (59%)
Frame = +1
Query: 49 TCQKCHITCGSCQGNGDQNCSTCIQHSHILLS 144
TC +CH +C C G + +C +C H H+ L+
Sbjct: 756 TCTECHPSCRQCHGPLESDCVSC--HPHLTLT 785
Score = 30.8 bits (68), Expect = 1.0
Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCI--QHS-HILLSD 147
C +C Q+ N C CH C C N S C+ QH+ H+LL D
Sbjct: 789 CKTSCKEEQFLNLVGY-CADCHPLCQHCVANLQDTGSICLKCQHARHLLLGD 839
Score = 30.0 bits (66), Expect = 1.8
Identities = 12/39 (30%), Positives = 18/39 (46%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C G Y + +C CH +C C G +++C C
Sbjct: 494 CVSTCGDGFYQDH--HSCAVCHESCAGCWGPTEKHCMAC 530
Score = 29.3 bits (64), Expect = 3.0
Identities = 12/39 (30%), Positives = 18/39 (46%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C +C G Y C+ CH +C +C G +C+ C
Sbjct: 636 CLPSCGEGFY--PDHGICEACHASCHTCVGPQPSHCTQC 672
>sp|Q63415|PCSK6_RAT Proprotein convertase subtilisin/kexin type 6 precursor (Paired
basic amino acid cleaving enzyme 4)
(Subtilisin/kexin-like protease PACE4) (Subtilisin-like
proprotein convertase 4) (SPC4)
Length = 937
Score = 38.1 bits (87), Expect = 0.006
Identities = 12/39 (30%), Positives = 19/39 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C G + +T + C++CH C +C G C +C
Sbjct: 697 CVSECPLGYFGDTAARRCRRCHKGCETCTGRSPTQCLSC 735
Score = 38.1 bits (87), Expect = 0.006
Identities = 14/44 (31%), Positives = 22/44 (50%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQHSH 132
C +C G Y+++ C +CH TC +C G + C C + H
Sbjct: 796 CIPDCEPGTYFDSELIRCGECHHTCRTCVGPSREECIHCAKSFH 839
Score = 29.6 bits (65), Expect = 2.3
Identities = 11/24 (45%), Positives = 16/24 (66%)
Frame = +1
Query: 46 KTCQKCHITCGSCQGNGDQNCSTC 117
K C++C C SC+G+ +NCS C
Sbjct: 864 KVCRRCDENCLSCEGS-SRNCSRC 886
>sp|P41413|PCSK5_RAT Proprotein convertase subtilisin/kexin type 5 precursor (Proprotein
convertase PC5) (Subtilisin/kexin-like protease PC5)
(rPC5) (PC6)
Length = 1877
Score = 37.7 bits (86), Expect = 0.008
Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 4/43 (9%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTT----KTCQKCHITCGSCQGNGDQNCSTC 117
C Q+C+ Y + + K+C++C +C +C G G +NCS+C
Sbjct: 816 CVQSCSVSYYLDHSLEGGYKSCKRCDNSCLTCNGPGFKNCSSC 858
Score = 37.0 bits (84), Expect = 0.014
Identities = 14/37 (37%), Positives = 22/37 (59%), Gaps = 2/37 (5%)
Frame = +1
Query: 13 CTTGQYWNTTTKT--CQKCHITCGSCQGNGDQNCSTC 117
C G+Y + + C+KCH +C C+G G +NC+ C
Sbjct: 1678 CIVGEYRDGKGENFNCKKCHESCMECKGPGSKNCTGC 1714
Score = 36.2 bits (82), Expect = 0.024
Identities = 14/41 (34%), Positives = 20/41 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTCIQ 123
C+ C GQ+++ CQ CH C +C G G C C +
Sbjct: 769 CSVTCEDGQFFSG--HDCQPCHRFCATCAGAGADGCINCTE 807
Score = 31.6 bits (70), Expect = 0.60
Identities = 13/39 (33%), Positives = 19/39 (48%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C +C G + + K C+KC C SC G+ C +C
Sbjct: 672 CVSSCPPGHF-HADKKRCRKCAPNCESCFGSHADQCLSC 709
Score = 30.8 bits (68), Expect = 1.0
Identities = 13/39 (33%), Positives = 16/39 (41%)
Frame = +1
Query: 1 CNQNCTTGQYWNTTTKTCQKCHITCGSCQGNGDQNCSTC 117
C C G Y + C KC C +C G NC+ C
Sbjct: 722 CVAQCPEGSYQDIKKNICGKCSENCKTC--TGFHNCTEC 758
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,058,599
Number of Sequences: 369166
Number of extensions: 232921
Number of successful extensions: 1208
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1065
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1202
length of database: 68,354,980
effective HSP length: 23
effective length of database: 64,106,075
effective search space used: 1730864025
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)