Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_023_H12 (780 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O76031|CLPX_HUMAN ATP-dependent Clp protease ATP-binding... 222 1e-57 sp|Q9JHS4|CLPX_MOUSE ATP-dependent Clp protease ATP-binding... 222 1e-57 sp|Q82Y56|CLPX_NITEU ATP-dependent Clp protease ATP-binding... 198 2e-50 sp|Q60BE7|CLPX2_METCA ATP-dependent Clp protease ATP-bindin... 197 2e-50 sp|Q8FN57|CLPX_COREF ATP-dependent Clp protease ATP-binding... 196 8e-50 sp|Q88VE2|CLPX_LACPL ATP-dependent Clp protease ATP-binding... 193 5e-49 sp|Q63V40|CLPX_BURPS ATP-dependent Clp protease ATP-binding... 192 7e-49 sp|Q7NUZ0|CLPX_CHRVO ATP-dependent Clp protease ATP-binding... 192 7e-49 sp|Q8D347|CLPX_WIGBR ATP-dependent Clp protease ATP-binding... 192 9e-49 sp|Q8K989|CLPX_BUCAP ATP-dependent Clp protease ATP-binding... 191 1e-48
>sp|O76031|CLPX_HUMAN ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor Length = 633 Score = 222 bits (565), Expect = 1e-57 Identities = 114/231 (49%), Positives = 167/231 (72%), Gaps = 1/231 (0%) Frame = +2 Query: 2 DEVDKISKKYILSSSCRDVGGEGVQQAFLKMLEGSTVNVPDSRSTRKARMDAIQVDTTNI 181 DEVDKI + RDVGGEGVQQ LK+LEG+ VNVP+ S RK R + +QVDTTNI Sbjct: 358 DEVDKIGSVPGIHQ-LRDVGGEGVQQGLLKLLEGTIVNVPEKNS-RKLRGETVQVDTTNI 415 Query: 182 LFIASGAFNGLDKIVKKRQQKDQSIGFSVDVLNKCDNKSSHGKYLDFNSKPDEIARNED- 358 LF+ASGAFNGLD+I+ +R+ ++ +GF + D ++ E ++D Sbjct: 416 LFVASGAFNGLDRIISRRKN-EKYLGFGTP--SNLGKGRRAAAAADLANRSGESNTHQDI 472 Query: 359 QDRDNLLKNIESKDLIEHGLIPEFVGRFPVIVALHSLNEDMLMRILVEPKNAIVSQYKCL 538 +++D LL+++E++DLIE G+IPEFVGR PV+V LHSL+E L++IL EP+NA++ QY+ L Sbjct: 473 EEKDRLLRHVEARDLIEFGMIPEFVGRLPVVVPLHSLDEKTLVQILTEPRNAVIPQYQAL 532 Query: 539 FNLDQCDLHITEDGLRAICKLAIAKQVGARGLRSILENILMDIRYEIPESD 691 F++D+C+L++TED L+AI +LA+ ++ GARGLRSI+E +L++ +E+P SD Sbjct: 533 FSMDKCELNVTEDALKAIARLALERKTGARGLRSIMEKLLLEPMFEVPNSD 583
>sp|Q9JHS4|CLPX_MOUSE ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor Length = 634 Score = 222 bits (565), Expect = 1e-57 Identities = 113/231 (48%), Positives = 170/231 (73%), Gaps = 1/231 (0%) Frame = +2 Query: 2 DEVDKISKKYILSSSCRDVGGEGVQQAFLKMLEGSTVNVPDSRSTRKARMDAIQVDTTNI 181 DEVDKI + RDVGGEGVQQ LK+LEG+ VNVP+ S RK R + +QVDTTN+ Sbjct: 359 DEVDKIGSVPGIHQ-LRDVGGEGVQQGLLKLLEGTIVNVPEKNS-RKLRGETVQVDTTNV 416 Query: 182 LFIASGAFNGLDKIVKKRQQKDQSIGFSVDVLNKCDNKSSHGKYLDFNSKPDEIARNED- 358 LF+ASGAFNGLD+I+ +R+ ++ +GF +++ + D ++ E ++D Sbjct: 417 LFVASGAFNGLDRIISRRKN-EKYLGFGTPSNLGKGRRAAAAR--DLANRSGESNTHQDI 473 Query: 359 QDRDNLLKNIESKDLIEHGLIPEFVGRFPVIVALHSLNEDMLMRILVEPKNAIVSQYKCL 538 +++D LL+++E++DLIE G+IPEFVGR PV+V LHSL+E L++IL EP+NA++ QY+ L Sbjct: 474 EEKDRLLRHVEARDLIEFGMIPEFVGRLPVVVPLHSLDEKTLVQILTEPRNAVIPQYQAL 533 Query: 539 FNLDQCDLHITEDGLRAICKLAIAKQVGARGLRSILENILMDIRYEIPESD 691 F++D+C+L++TED L+AI +LA+ ++ GARGLRSI+E +L++ +E+P SD Sbjct: 534 FSMDKCELNVTEDALKAIARLALERKTGARGLRSIMEKLLLEPMFEVPNSD 584
>sp|Q82Y56|CLPX_NITEU ATP-dependent Clp protease ATP-binding subunit clpX Length = 426 Score = 198 bits (503), Expect = 2e-50 Identities = 108/228 (47%), Positives = 147/228 (64%), Gaps = 1/228 (0%) Frame = +2 Query: 2 DEVDKISKKYILSSSCRDVGGEGVQQAFLKMLEGSTVNVPDSRSTRKARMDAIQVDTTNI 181 DE+DKIS+K S RDV GEGVQQA LK++EG+T VP + + IQ+DTTNI Sbjct: 186 DEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTTALVPPQGGRKHPNQEFIQIDTTNI 245 Query: 182 LFIASGAFNGLDKIVKKRQQKDQSIGFSVDVLNKCDNKSSHGKYLDFNSKPDEIARNEDQ 361 LFI GAF+G+DKI++ R +K IGF DV+N+ D K Sbjct: 246 LFICGGAFDGIDKIIRGRSEK-SGIGFGADVINQNDRK---------------------- 282 Query: 362 DRDNLLKNIESKDLIEHGLIPEFVGRFPVIVALHSLNEDMLMRILVEPKNAIVSQYKCLF 541 + + +LK+IE +DLI++GLIPEFVGR PV+ L LNE L++ILVEPKNA++ QY LF Sbjct: 283 ELNKILKDIEPEDLIKYGLIPEFVGRLPVVATLSELNEAALIQILVEPKNALIKQYNKLF 342 Query: 542 NLD-QCDLHITEDGLRAICKLAIAKQVGARGLRSILENILMDIRYEIP 682 +++ +L E L AI + A++++ GARGLRSILE L+DI Y++P Sbjct: 343 SMEGGVELEFREQALVAIARKALSRKTGARGLRSILEETLLDIMYDLP 390
>sp|Q60BE7|CLPX2_METCA ATP-dependent Clp protease ATP-binding subunit clpX 2 Length = 428 Score = 197 bits (502), Expect = 2e-50 Identities = 104/230 (45%), Positives = 149/230 (64%) Frame = +2 Query: 2 DEVDKISKKYILSSSCRDVGGEGVQQAFLKMLEGSTVNVPDSRSTRKARMDAIQVDTTNI 181 DE+DKIS+K S RDV GEGVQQA LK++EG+ +VP + + + +QV+T NI Sbjct: 188 DEIDKISRKADNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVNTANI 247 Query: 182 LFIASGAFNGLDKIVKKRQQKDQSIGFSVDVLNKCDNKSSHGKYLDFNSKPDEIARNEDQ 361 LFI GAF GL+KI++ R ++ IGF+ DV +K D+++ Sbjct: 248 LFICGGAFAGLEKIIRSRSEQG-GIGFAADVKSKDDSRNV-------------------- 286 Query: 362 DRDNLLKNIESKDLIEHGLIPEFVGRFPVIVALHSLNEDMLMRILVEPKNAIVSQYKCLF 541 +L ++E++DLI +GLIPEFVGR PV+ L L+E L+RIL EPKNA+V QY+ LF Sbjct: 287 --GEVLADVEAEDLIRYGLIPEFVGRLPVVATLEELDEAALVRILTEPKNALVKQYRRLF 344 Query: 542 NLDQCDLHITEDGLRAICKLAIAKQVGARGLRSILENILMDIRYEIPESD 691 ++ C+L I +D L AI + A+A++ GARGLR+ILE+ L+D YE+P S+ Sbjct: 345 EMESCELEIRDDALGAIARKAMARKTGARGLRTILEHTLLDTMYELPSSE 394
>sp|Q8FN57|CLPX_COREF ATP-dependent Clp protease ATP-binding subunit clpX Length = 426 Score = 196 bits (497), Expect = 8e-50 Identities = 101/230 (43%), Positives = 151/230 (65%) Frame = +2 Query: 2 DEVDKISKKYILSSSCRDVGGEGVQQAFLKMLEGSTVNVPDSRSTRKARMDAIQVDTTNI 181 DEVDKIS+K S RDV GEGVQQA LK+LEG+ +P + D IQ+DTTNI Sbjct: 191 DEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQDFIQLDTTNI 250 Query: 182 LFIASGAFNGLDKIVKKRQQKDQSIGFSVDVLNKCDNKSSHGKYLDFNSKPDEIARNEDQ 361 LFI +GAF+GL+KI+ +R+ K + +GF V+V +K +D+ Sbjct: 251 LFIVAGAFSGLEKIIGERRGK-KGLGFGVEVASK-----------------------KDE 286 Query: 362 DRDNLLKNIESKDLIEHGLIPEFVGRFPVIVALHSLNEDMLMRILVEPKNAIVSQYKCLF 541 +++++ K++ +DL++ GLIPEF+GR PV+ + +L+++ L+++L EP+N++V QYK LF Sbjct: 287 EKEDIFKDVRPEDLVKFGLIPEFIGRLPVVATVANLDQESLVKVLTEPRNSLVKQYKRLF 346 Query: 542 NLDQCDLHITEDGLRAICKLAIAKQVGARGLRSILENILMDIRYEIPESD 691 +D L T+D L AI LA+ ++ GARGLR+ILE IL+ I Y+IP+ D Sbjct: 347 EMDDTLLTFTDDALEAIADLALERKTGARGLRAILEEILVPIMYDIPDRD 396
>sp|Q88VE2|CLPX_LACPL ATP-dependent Clp protease ATP-binding subunit clpX Length = 421 Score = 193 bits (490), Expect = 5e-49 Identities = 108/230 (46%), Positives = 147/230 (63%) Frame = +2 Query: 2 DEVDKISKKYILSSSCRDVGGEGVQQAFLKMLEGSTVNVPDSRSTRKARMDAIQVDTTNI 181 DE+DKI+KK S RDV GEGVQQA LK+LEG+ NVP + + + IQ+DTTNI Sbjct: 186 DEIDKIAKKSENVSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPQQEFIQIDTTNI 245 Query: 182 LFIASGAFNGLDKIVKKRQQKDQSIGFSVDVLNKCDNKSSHGKYLDFNSKPDEIARNEDQ 361 LFI GAF+G++ IVK+R D++IGF D D K++ LD Sbjct: 246 LFIVGGAFDGIEDIVKRRLG-DKTIGFGTDT----DGKNA---VLD-------------- 283 Query: 362 DRDNLLKNIESKDLIEHGLIPEFVGRFPVIVALHSLNEDMLMRILVEPKNAIVSQYKCLF 541 D +L++ + +DL++ GLIPEF+GR P++ AL L ED L+RIL EPKNA+V QY+ L Sbjct: 284 DSKSLMQQVVPEDLLQFGLIPEFIGRLPILTALERLTEDDLVRILTEPKNALVKQYQRLI 343 Query: 542 NLDQCDLHITEDGLRAICKLAIAKQVGARGLRSILENILMDIRYEIPESD 691 LD +L +D LRAI + A+A+ GARGLRSI+E+ + DI Y+IP + Sbjct: 344 ALDGAELDFNDDALRAIAQEALARNTGARGLRSIIEDTMRDIMYDIPSRE 393
>sp|Q63V40|CLPX_BURPS ATP-dependent Clp protease ATP-binding subunit clpX Length = 423 Score = 192 bits (489), Expect = 7e-49 Identities = 103/227 (45%), Positives = 143/227 (62%) Frame = +2 Query: 2 DEVDKISKKYILSSSCRDVGGEGVQQAFLKMLEGSTVNVPDSRSTRKARMDAIQVDTTNI 181 DE+DKIS+K S RDV GEGVQQA LK++EG+ +VP + D IQVDTTNI Sbjct: 186 DEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQVDTTNI 245 Query: 182 LFIASGAFNGLDKIVKKRQQKDQSIGFSVDVLNKCDNKSSHGKYLDFNSKPDEIARNEDQ 361 LFI GAF+GL+K++ R +K IGF V +K +++ Sbjct: 246 LFICGGAFDGLEKVITDRTEKT-GIGFGATVKSK-----------------------QER 281 Query: 362 DRDNLLKNIESKDLIEHGLIPEFVGRFPVIVALHSLNEDMLMRILVEPKNAIVSQYKCLF 541 D +L+ +E +DLI+ GLIPE +GR PV+ L L+E LM+ILVEPKNA+V QY+ LF Sbjct: 282 DAGEVLREVEPEDLIKFGLIPELIGRLPVVATLGKLDEAALMKILVEPKNALVKQYQKLF 341 Query: 542 NLDQCDLHITEDGLRAICKLAIAKQVGARGLRSILENILMDIRYEIP 682 +++ +L I D L+A+ + AI ++ GARGLRSI+E L+D+ YE+P Sbjct: 342 AMERVELEIRPDALQAVARKAIRRKTGARGLRSIIEQALLDVMYELP 388
>sp|Q7NUZ0|CLPX_CHRVO ATP-dependent Clp protease ATP-binding subunit clpX Length = 426 Score = 192 bits (489), Expect = 7e-49 Identities = 103/227 (45%), Positives = 140/227 (61%) Frame = +2 Query: 2 DEVDKISKKYILSSSCRDVGGEGVQQAFLKMLEGSTVNVPDSRSTRKARMDAIQVDTTNI 181 DE+DKIS+K S RDV GEGVQQA LK++EG+ +VP + + IQVDTTNI Sbjct: 188 DEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQEFIQVDTTNI 247 Query: 182 LFIASGAFNGLDKIVKKRQQKDQSIGFSVDVLNKCDNKSSHGKYLDFNSKPDEIARNEDQ 361 LFI GAF+GLDKI+++R +K IGF +V +K D KS Sbjct: 248 LFICGGAFDGLDKIIRQRSEKG-GIGFGAEVSSKDDGKSL-------------------- 286 Query: 362 DRDNLLKNIESKDLIEHGLIPEFVGRFPVIVALHSLNEDMLMRILVEPKNAIVSQYKCLF 541 L + +E +D+I GLIPE +GR PV+ L L+E+ L+ IL +PKNA++ QY+ LF Sbjct: 287 --TKLFQEVEPQDIIRFGLIPELIGRLPVVATLEELDEEALVSILTQPKNALIKQYQKLF 344 Query: 542 NLDQCDLHITEDGLRAICKLAIAKQVGARGLRSILENILMDIRYEIP 682 +L+ +L + LR I K A+A++ GARGLRSILE L+D YE+P Sbjct: 345 SLETVELEVRPSALRVIAKQALARKTGARGLRSILERALLDTMYELP 391
>sp|Q8D347|CLPX_WIGBR ATP-dependent Clp protease ATP-binding subunit clpX Length = 415 Score = 192 bits (488), Expect = 9e-49 Identities = 106/227 (46%), Positives = 143/227 (62%) Frame = +2 Query: 2 DEVDKISKKYILSSSCRDVGGEGVQQAFLKMLEGSTVNVPDSRSTRKARMDAIQVDTTNI 181 DE+DKIS+K S RDV GEGVQQA LK++EG+ VP + + + VDTTNI Sbjct: 185 DEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTISAVPKKGGRKHPQQEFFHVDTTNI 244 Query: 182 LFIASGAFNGLDKIVKKRQQKDQSIGFSVDVLNKCDNKSSHGKYLDFNSKPDEIARNEDQ 361 LFI GAF+GL+KI+++R SIGF+VD+ NK L+ N+K Sbjct: 245 LFICGGAFSGLNKIIEQRVLVKNSIGFNVDINNK----------LNINNKK--------- 285 Query: 362 DRDNLLKNIESKDLIEHGLIPEFVGRFPVIVALHSLNEDMLMRILVEPKNAIVSQYKCLF 541 N L ++ +DLI+ GLIPEFVGR P+I L LN L+ IL++PKNA+V QYK LF Sbjct: 286 ---NFLSQVQPEDLIKFGLIPEFVGRLPIISVLKELNISELIEILIQPKNALVKQYKLLF 342 Query: 542 NLDQCDLHITEDGLRAICKLAIAKQVGARGLRSILENILMDIRYEIP 682 NL+ +L E+ L +I K ++ K+ GARGLRSI+E+IL+D Y +P Sbjct: 343 NLEGVELEFNENALISIAKESLHKKTGARGLRSIIEHILLDTMYSLP 389
>sp|Q8K989|CLPX_BUCAP ATP-dependent Clp protease ATP-binding subunit clpX Length = 427 Score = 191 bits (486), Expect = 1e-48 Identities = 100/227 (44%), Positives = 144/227 (63%) Frame = +2 Query: 2 DEVDKISKKYILSSSCRDVGGEGVQQAFLKMLEGSTVNVPDSRSTRKARMDAIQVDTTNI 181 DE+DKIS+K S RDV GEGVQQA LK++EG+ ++P + + + +QV+T NI Sbjct: 186 DEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTLASIPPQGGRKHPQQEFLQVNTANI 245 Query: 182 LFIASGAFNGLDKIVKKRQQKDQSIGFSVDVLNKCDNKSSHGKYLDFNSKPDEIARNEDQ 361 LFI +GAF+ L KI+ KR +IGF+ ++ + KS Sbjct: 246 LFICAGAFSELSKIISKRIDTGNTIGFNCNLKKQKKKKSEQ------------------- 286 Query: 362 DRDNLLKNIESKDLIEHGLIPEFVGRFPVIVALHSLNEDMLMRILVEPKNAIVSQYKCLF 541 L+ ++SKDLI+ GLIPEF+GR P+I L LNE L++IL +PKNA++ QY+ LF Sbjct: 287 ---YFLQQVQSKDLIKFGLIPEFIGRLPIITILKELNETALVQILCKPKNALIKQYQTLF 343 Query: 542 NLDQCDLHITEDGLRAICKLAIAKQVGARGLRSILENILMDIRYEIP 682 NL++ L T++ + +I K A++K+ GARGLRSI+ENIL+DI YE+P Sbjct: 344 NLEKVKLEFTKEAVTSIAKKALSKKTGARGLRSIIENILLDIMYELP 390
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 77,528,012 Number of Sequences: 369166 Number of extensions: 1408476 Number of successful extensions: 4620 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4147 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4336 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 7308943600 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)