Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_H10
(453 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor 89 6e-18
sp|Q9R014|CATJ_MOUSE Cathepsin J precursor (Cathepsin P) (C... 82 5e-16
sp|Q9JIA9|CATR_MOUSE Cathepsin R precursor 80 3e-15
sp|Q8HY81|CATS_CANFA Cathepsin S precursor 77 1e-14
sp|P25774|CATS_HUMAN Cathepsin S precursor 77 1e-14
sp|Q8HY82|CATS_SAIBB Cathepsin S precursor 77 2e-14
sp|P12400|CTL2B_MOUSE CTLA-2-beta protein precursor 72 4e-13
sp|O70370|CATS_MOUSE Cathepsin S precursor 72 4e-13
sp|Q02765|CATS_RAT Cathepsin S precursor 72 7e-13
sp|Q9QZE3|CATQ_RAT Cathepsin Q precursor 71 1e-12
>sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor
Length = 326
Score = 88.6 bits (218), Expect = 6e-18
Identities = 47/125 (37%), Positives = 70/125 (56%), Gaps = 6/125 (4%)
Frame = +3
Query: 60 WEDYKTIFNKKYSDETDLIRRNIWEENLKFIKQHNLQFDLGKTKFSVGLNEFSDMNQKEF 239
W +K ++NK+Y+ D RRNIWE+N+K I++HNL+ DLG +++GLN+F+DM +EF
Sbjct: 21 WHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEF 80
Query: 240 QSNILSVXXXXXXXXXXXXXXXXXXLSRNDFITT------PNNIKLPDSCDWREKGAVSP 401
++ L+ +SR I + NN +PD DWRE G V+
Sbjct: 81 KAKYLT------------------EMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTE 122
Query: 402 VGDQG 416
V DQG
Sbjct: 123 VKDQG 127
>sp|Q9R014|CATJ_MOUSE Cathepsin J precursor (Cathepsin P) (Catlrp-p)
Length = 333
Score = 82.0 bits (201), Expect = 5e-16
Identities = 45/129 (34%), Positives = 72/129 (55%), Gaps = 5/129 (3%)
Frame = +3
Query: 45 QLNKDWEDYKTIFNKKYSDETDLIRRNIWEENLKFIKQHNLQFDLGKTKFSVGLNEFSDM 224
+L+ +W+D+KT + K YS E + +RR +WEEN++ IK HN + LGK F++ +N+F D
Sbjct: 24 KLDAEWKDWKTKYAKSYSPE-EALRRAVWEENMRMIKLHNKENSLGKNNFTMKMNKFGDQ 82
Query: 225 NQKEFQSNILSVXXXXXXXXXXXXXXXXXXLSRNDFITTPN-----NIKLPDSCDWREKG 389
+EF+ +I ++ +T P+ +I LPD DWRE+G
Sbjct: 83 TSEEFRKSIDNIPIPAA-------------------MTDPHAQNHVSIGLPDYKDWREEG 123
Query: 390 AVSPVGDQG 416
V+PV +QG
Sbjct: 124 YVTPVRNQG 132
>sp|Q9JIA9|CATR_MOUSE Cathepsin R precursor
Length = 334
Score = 79.7 bits (195), Expect = 3e-15
Identities = 41/127 (32%), Positives = 65/127 (51%)
Frame = +3
Query: 36 VNSQLNKDWEDYKTIFNKKYSDETDLIRRNIWEENLKFIKQHNLQFDLGKTKFSVGLNEF 215
++S L+ +W+D+K +NK YS + + ++R +WEE LK IK HN + LGK F++ +NEF
Sbjct: 21 LDSSLDAEWQDWKIKYNKSYSLKEEKLKRVVWEEKLKMIKLHNRENSLGKNGFTMKMNEF 80
Query: 216 SDMNQKEFQSNILSVXXXXXXXXXXXXXXXXXXLSRNDFITTPNNIKLPDSCDWREKGAV 395
D +EF+ ++ + + LP DWR+KG V
Sbjct: 81 GDQTDEEFRKMMIEISVWTHREGKSIMKREAGSI-------------LPKFVDWRKKGYV 127
Query: 396 SPVGDQG 416
+PV QG
Sbjct: 128 TPVRRQG 134
>sp|Q8HY81|CATS_CANFA Cathepsin S precursor
Length = 331
Score = 77.4 bits (189), Expect = 1e-14
Identities = 44/125 (35%), Positives = 66/125 (52%), Gaps = 1/125 (0%)
Frame = +3
Query: 48 LNKDWEDYKTIFNKKYSDETDLI-RRNIWEENLKFIKQHNLQFDLGKTKFSVGLNEFSDM 224
L+ W +K ++K+Y +E + + RR IWE+NLKF+ HNL+ +G + +G+N DM
Sbjct: 24 LDHHWNLWKKTYSKQYKEENEEVARRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDM 83
Query: 225 NQKEFQSNILSVXXXXXXXXXXXXXXXXXXLSRNDFITTPNNIKLPDSCDWREKGAVSPV 404
+E S + S+ RN + +N KLPDS DWREKG V+ V
Sbjct: 84 TGEEVISLMGSLRVPSQW-------------QRNVTYRSNSNQKLPDSVDWREKGCVTEV 130
Query: 405 GDQGT 419
QG+
Sbjct: 131 KYQGS 135
>sp|P25774|CATS_HUMAN Cathepsin S precursor
Length = 331
Score = 77.4 bits (189), Expect = 1e-14
Identities = 48/138 (34%), Positives = 72/138 (52%), Gaps = 8/138 (5%)
Frame = +3
Query: 30 SNVNSQLNKD------WEDYKTIFNKKYSDETD-LIRRNIWEENLKFIKQHNLQFDLGKT 188
S+ +QL+KD W +K + K+Y ++ + +RR IWE+NLKF+ HNL+ +G
Sbjct: 12 SSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMH 71
Query: 189 KFSVGLNEFSDMNQKEFQSNILSVXXXXXXXXXXXXXXXXXXLSRN-DFITTPNNIKLPD 365
+ +G+N DM +E S + S+ RN + + PN I LPD
Sbjct: 72 SYDLGMNHLGDMTSEEVMSLMSSLRVPSQW-------------QRNITYKSNPNRI-LPD 117
Query: 366 SCDWREKGAVSPVGDQGT 419
S DWREKG V+ V QG+
Sbjct: 118 SVDWREKGCVTEVKYQGS 135
>sp|Q8HY82|CATS_SAIBB Cathepsin S precursor
Length = 330
Score = 77.0 bits (188), Expect = 2e-14
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 7/137 (5%)
Frame = +3
Query: 30 SNVNSQLNKD------WEDYKTIFNKKYSDETD-LIRRNIWEENLKFIKQHNLQFDLGKT 188
S+ +QL+KD W +K + K+Y ++ + +RR IWE+NLKF+ HNL+ +G
Sbjct: 12 SSAVTQLHKDPTLDHHWNLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMH 71
Query: 189 KFSVGLNEFSDMNQKEFQSNILSVXXXXXXXXXXXXXXXXXXLSRNDFITTPNNIKLPDS 368
+ +G+N DM +E S + S+ RN + N LPDS
Sbjct: 72 SYDLGMNHLGDMTSEEVMSLMSSLRVPNQW-------------QRNITYKSNPNQMLPDS 118
Query: 369 CDWREKGAVSPVGDQGT 419
DWREKG V+ V QG+
Sbjct: 119 VDWREKGCVTEVKYQGS 135
>sp|P12400|CTL2B_MOUSE CTLA-2-beta protein precursor
Length = 141
Score = 72.4 bits (176), Expect = 4e-13
Identities = 31/67 (46%), Positives = 48/67 (71%)
Frame = +3
Query: 48 LNKDWEDYKTIFNKKYSDETDLIRRNIWEENLKFIKQHNLQFDLGKTKFSVGLNEFSDMN 227
L+ +W+++KT F K YS + + RR +WEEN K I+ HN ++ GKT F +GLN+FSD+
Sbjct: 40 LDNEWKEWKTTFAKAYSLDEERHRRLMWEENKKKIEAHNADYERGKTSFYMGLNQFSDLT 99
Query: 228 QKEFQSN 248
+EF++N
Sbjct: 100 PEEFRTN 106
>sp|O70370|CATS_MOUSE Cathepsin S precursor
Length = 340
Score = 72.4 bits (176), Expect = 4e-13
Identities = 43/129 (33%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Frame = +3
Query: 48 LNKDWEDYKTIFNKKYSDETDL-IRRNIWEENLKFIKQHNLQFDLGKTKFSVGLNEFSDM 224
L+ W+ +K K+Y D+ + +RR IWE+NLKFI HNL++ +G + VG+N+ DM
Sbjct: 32 LDYHWDLWKKTHEKEYKDKNEEEVRRLIWEKNLKFIMIHNLEYSMGMHTYQVGMNDMGDM 91
Query: 225 NQKEFQSNILSVXXXXXXXXXXXXXXXXXXLSRNDFITTP----NNIKLPDSCDWREKGA 392
+E + ++ +SR T +N LPD+ DWREKG
Sbjct: 92 TNEEISCRMGAL-----------------RISRQSPKTVTFRSYSNRTLPDTVDWREKGC 134
Query: 393 VSPVGDQGT 419
V+ V QG+
Sbjct: 135 VTEVKYQGS 143
>sp|Q02765|CATS_RAT Cathepsin S precursor
Length = 330
Score = 71.6 bits (174), Expect = 7e-13
Identities = 42/125 (33%), Positives = 66/125 (52%), Gaps = 1/125 (0%)
Frame = +3
Query: 48 LNKDWEDYKTIFNKKYSDETDL-IRRNIWEENLKFIKQHNLQFDLGKTKFSVGLNEFSDM 224
L+ W+ +K ++ +D+ + +RR IWE+NLKFI HNL+ +G +SVG+N DM
Sbjct: 22 LDHHWDLWKKTRMRRNTDQNEEDVRRLIWEKNLKFIMLHNLEHSMGMHSYSVGMNHMGDM 81
Query: 225 NQKEFQSNILSVXXXXXXXXXXXXXXXXXXLSRNDFITTPNNIKLPDSCDWREKGAVSPV 404
+E + S+ +R+ + + +N LPDS DWREKG V+ V
Sbjct: 82 TPEEVIGYMGSLRIPRPW-------------NRSGTLKSSSNQTLPDSVDWREKGCVTNV 128
Query: 405 GDQGT 419
QG+
Sbjct: 129 KYQGS 133
>sp|Q9QZE3|CATQ_RAT Cathepsin Q precursor
Length = 343
Score = 70.9 bits (172), Expect = 1e-12
Identities = 38/129 (29%), Positives = 65/129 (50%)
Frame = +3
Query: 30 SNVNSQLNKDWEDYKTIFNKKYSDETDLIRRNIWEENLKFIKQHNLQFDLGKTKFSVGLN 209
S ++ L+ W+++K + K YS E ++++R +WEEN+K I+ HN + LGK +++ +N
Sbjct: 19 SALDLSLDVQWQEWKIKYEKLYSPEEEVLKRVVWEENVKKIELHNRENSLGKNTYTMEIN 78
Query: 210 EFSDMNQKEFQSNILSVXXXXXXXXXXXXXXXXXXLSRNDFITTPNNIKLPDSCDWREKG 389
+F+DM +EF+ I+ N + LP DWR +G
Sbjct: 79 DFADMTDEEFKDMIIGFQLPVHNTEKRLWKRALGSFFPNSWNWRD---ALPKFVDWRNEG 135
Query: 390 AVSPVGDQG 416
V+ V QG
Sbjct: 136 YVTRVRKQG 144
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,327,560
Number of Sequences: 369166
Number of extensions: 554223
Number of successful extensions: 2199
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2053
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2129
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2435140505
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)