Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_E01
(723 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q02748|IF4A_DROME Eukaryotic initiation factor 4A (eIF4A... 331 1e-90
sp|P60842|IF4A1_HUMAN Eukaryotic initiation factor 4A-I (eI... 328 9e-90
sp|Q4R8K5|IF4A1_MACFA Eukaryotic initiation factor 4A-I (eI... 328 9e-90
sp|P29562|IF4A1_RABIT Eukaryotic initiation factor 4A-I (eI... 328 9e-90
sp|P10630|IF4A2_MOUSE Eukaryotic initiation factor 4A-II (e... 323 2e-88
sp|Q5R5F5|IF4A1_PONPY Eukaryotic initiation factor 4A-I (eI... 323 4e-88
sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A... 322 6e-88
sp|Q4R4Y9|IF4A2_MACFA Eukaryotic initiation factor 4A-II (e... 321 1e-87
sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A... 319 4e-87
sp|P35683|IF4A_ORYSA Eukaryotic initiation factor 4A (eIF4A... 309 6e-84
>sp|Q02748|IF4A_DROME Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 403
Score = 331 bits (848), Expect = 1e-90
Identities = 165/238 (69%), Positives = 197/238 (82%)
Frame = +1
Query: 10 MENPGEIETNYEKVTESFDDMNLKEDLLRGIYAYGFEKPSAIQQRAVLPAIEGHDVIAQA 189
ME G IE+ + +V ++FDDMNL+E+LLRGIY YGFEKPSAIQQRA++P + G DVIAQA
Sbjct: 15 MEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQA 74
Query: 190 QSGTGKTATFSVAILQRIDVTKNEVQALVLAPTRELAKQIHKVIIALGDYMGAKSYACIG 369
QSGTGKTATFS+AILQ+ID + E QAL+LAPTRELA QI +V++ALG+YM S+ACIG
Sbjct: 75 QSGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHACIG 134
Query: 370 GTRVQEDVGNLENGVHVIVGTPGRVNDMIERGNLKTNSIKMFVLDEADEMLSRGFKEQIH 549
GT V+ED LE+G HV+VGTPGRV DMI R L+T IK+FVLDEADEMLSRGFK+QI
Sbjct: 135 GTNVREDARILESGCHVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQ 194
Query: 550 SVIQFIEHDTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSE 723
V + + D Q++LLSATMPPDVLEV+R FMR PV ILVKKEELTLEGI+QFYVNV +
Sbjct: 195 DVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQ 252
>sp|P60842|IF4A1_HUMAN Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
sp|P60843|IF4A1_MOUSE Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 328 bits (841), Expect = 9e-90
Identities = 165/237 (69%), Positives = 198/237 (83%), Gaps = 1/237 (0%)
Frame = +1
Query: 10 MENPGEIETNYEKVTESFDDMNLKEDLLRGIYAYGFEKPSAIQQRAVLPAIEGHDVIAQA 189
ME G IE+N+ ++ +SFDDMNL E LLRGIYAYGFEKPSAIQQRA+LP I+G+DVIAQA
Sbjct: 17 MEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQA 76
Query: 190 QSGTGKTATFSVAILQRIDVTKNEVQALVLAPTRELAKQIHKVIIALGDYMGAKSYACIG 369
QSGTGKTATF+++ILQ+I++ QALVLAPTRELA+QI KV++ALGDYMGA +ACIG
Sbjct: 77 QSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIG 136
Query: 370 GTRVQEDVGNLE-NGVHVIVGTPGRVNDMIERGNLKTNSIKMFVLDEADEMLSRGFKEQI 546
GT V+ +V L+ H+IVGTPGRV DM+ R L IKMFVLDEADEMLSRGFK+QI
Sbjct: 137 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQI 196
Query: 547 HSVIQFIEHDTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNV 717
+ + Q + +TQ+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGIRQFY+NV
Sbjct: 197 YDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINV 253
>sp|Q4R8K5|IF4A1_MACFA Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 328 bits (841), Expect = 9e-90
Identities = 165/237 (69%), Positives = 198/237 (83%), Gaps = 1/237 (0%)
Frame = +1
Query: 10 MENPGEIETNYEKVTESFDDMNLKEDLLRGIYAYGFEKPSAIQQRAVLPAIEGHDVIAQA 189
ME G IE+N+ ++ +SFDDMNL E LLRGIYAYGFEKPSAIQQRA+LP I+G+DVIAQA
Sbjct: 17 MEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQA 76
Query: 190 QSGTGKTATFSVAILQRIDVTKNEVQALVLAPTRELAKQIHKVIIALGDYMGAKSYACIG 369
QSGTGKTATF+++ILQ+I++ QALVLAPTRELA+QI KV++ALGDYMGA +ACIG
Sbjct: 77 QSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIG 136
Query: 370 GTRVQEDVGNLE-NGVHVIVGTPGRVNDMIERGNLKTNSIKMFVLDEADEMLSRGFKEQI 546
GT V+ +V L+ H+IVGTPGRV DM+ R L IKMFVLDEADEMLSRGFK+QI
Sbjct: 137 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQI 196
Query: 547 HSVIQFIEHDTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNV 717
+ + Q + +TQ+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGIRQFY+NV
Sbjct: 197 YDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINV 253
>sp|P29562|IF4A1_RABIT Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 398
Score = 328 bits (841), Expect = 9e-90
Identities = 165/237 (69%), Positives = 198/237 (83%), Gaps = 1/237 (0%)
Frame = +1
Query: 10 MENPGEIETNYEKVTESFDDMNLKEDLLRGIYAYGFEKPSAIQQRAVLPAIEGHDVIAQA 189
ME G IE+N+ ++ +SFDDMNL E LLRGIYAYGFEKPSAIQQRA+LP I+G+DVIAQA
Sbjct: 9 MEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQA 68
Query: 190 QSGTGKTATFSVAILQRIDVTKNEVQALVLAPTRELAKQIHKVIIALGDYMGAKSYACIG 369
QSGTGKTATF+++ILQ+I++ QALVLAPTRELA+QI KV++ALGDYMGA +ACIG
Sbjct: 69 QSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIG 128
Query: 370 GTRVQEDVGNLE-NGVHVIVGTPGRVNDMIERGNLKTNSIKMFVLDEADEMLSRGFKEQI 546
GT V+ +V L+ H+IVGTPGRV DM+ R L IKMFVLDEADEMLSRGFK+QI
Sbjct: 129 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQI 188
Query: 547 HSVIQFIEHDTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNV 717
+ + Q + +TQ+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGIRQFY+NV
Sbjct: 189 YDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINV 245
>sp|P10630|IF4A2_MOUSE Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
sp|Q14240|IF4A2_HUMAN Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
sp|Q5R4X1|IF4A2_PONPY Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
Length = 407
Score = 323 bits (829), Expect = 2e-88
Identities = 160/237 (67%), Positives = 198/237 (83%), Gaps = 1/237 (0%)
Frame = +1
Query: 10 MENPGEIETNYEKVTESFDDMNLKEDLLRGIYAYGFEKPSAIQQRAVLPAIEGHDVIAQA 189
M+ G IE+N+ ++ ++FDDMNLKE LLRGIYAYGFEKPSAIQQRA++P I+G+DVIAQA
Sbjct: 18 MDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQA 77
Query: 190 QSGTGKTATFSVAILQRIDVTKNEVQALVLAPTRELAKQIHKVIIALGDYMGAKSYACIG 369
QSGTGKTATF+++ILQ++++ E QALVLAPTRELA+QI KVI+ALGDYMGA +ACIG
Sbjct: 78 QSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIG 137
Query: 370 GTRVQEDVGNLE-NGVHVIVGTPGRVNDMIERGNLKTNSIKMFVLDEADEMLSRGFKEQI 546
GT V+ ++ L+ H++VGTPGRV DM+ R L IKMFVLDEADEMLSRGFK+QI
Sbjct: 138 GTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQI 197
Query: 547 HSVIQFIEHDTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNV 717
+ + Q + Q+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGI+QFY+NV
Sbjct: 198 YEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINV 254
>sp|Q5R5F5|IF4A1_PONPY Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 323 bits (827), Expect = 4e-88
Identities = 163/237 (68%), Positives = 196/237 (82%), Gaps = 1/237 (0%)
Frame = +1
Query: 10 MENPGEIETNYEKVTESFDDMNLKEDLLRGIYAYGFEKPSAIQQRAVLPAIEGHDVIAQA 189
ME G IE+N+ ++ +S DDMNL E LLRGIYAYGFEKPSAIQQRA+L I+G+DVIAQA
Sbjct: 17 MEPEGVIESNWNEIVDSLDDMNLSESLLRGIYAYGFEKPSAIQQRAILSCIKGYDVIAQA 76
Query: 190 QSGTGKTATFSVAILQRIDVTKNEVQALVLAPTRELAKQIHKVIIALGDYMGAKSYACIG 369
QSGTGKTATF+++ILQ+I++ QALVLAPTRELA+QI KV++ALGDYMGA +ACIG
Sbjct: 77 QSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIG 136
Query: 370 GTRVQEDVGNLE-NGVHVIVGTPGRVNDMIERGNLKTNSIKMFVLDEADEMLSRGFKEQI 546
GT V+ +V L+ H+IVGTPGRV DM+ R L IKMFVLDEADEMLSRGFK+QI
Sbjct: 137 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQI 196
Query: 547 HSVIQFIEHDTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNV 717
+ + Q + +TQ+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGIRQFY+NV
Sbjct: 197 YDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINV 253
>sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 392
Score = 322 bits (825), Expect = 6e-88
Identities = 155/232 (66%), Positives = 198/232 (85%)
Frame = +1
Query: 28 IETNYEKVTESFDDMNLKEDLLRGIYAYGFEKPSAIQQRAVLPAIEGHDVIAQAQSGTGK 207
IETNY++V ++FDDMNLK +LLRGIYAYGFE+PSAIQQRA++P + DV+AQAQSGTGK
Sbjct: 10 IETNYDEVIDTFDDMNLKPELLRGIYAYGFERPSAIQQRAIMPILGERDVLAQAQSGTGK 69
Query: 208 TATFSVAILQRIDVTKNEVQALVLAPTRELAKQIHKVIIALGDYMGAKSYACIGGTRVQE 387
TATFS+++LQ+ID + + QAL+LAPTRELA+QI KV++ALGD M + +ACIGGT V++
Sbjct: 70 TATFSISVLQKIDTSLKQCQALILAPTRELAQQIQKVVVALGDLMNVECHACIGGTLVRD 129
Query: 388 DVGNLENGVHVIVGTPGRVNDMIERGNLKTNSIKMFVLDEADEMLSRGFKEQIHSVIQFI 567
D+ L+ GVHV+VGTPGRV+DMI+R L T++++MFVLDEADEMLSRGFK+QI+ + Q +
Sbjct: 130 DMAALQAGVHVVVGTPGRVHDMIQRRALPTDAVQMFVLDEADEMLSRGFKDQIYDIFQLL 189
Query: 568 EHDTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSE 723
Q+VLLSATMP DVLEVT KFMR P++ILVKK+ELTLEGI+QFYV V +
Sbjct: 190 PPTAQVVLLSATMPQDVLEVTTKFMRDPIRILVKKDELTLEGIKQFYVAVEK 241
>sp|Q4R4Y9|IF4A2_MACFA Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
Length = 408
Score = 321 bits (822), Expect = 1e-87
Identities = 159/237 (67%), Positives = 197/237 (83%), Gaps = 1/237 (0%)
Frame = +1
Query: 10 MENPGEIETNYEKVTESFDDMNLKEDLLRGIYAYGFEKPSAIQQRAVLPAIEGHDVIAQA 189
M+ G IE+N+ ++ ++FDDMNLKE LLRGIYAYGFEKPSAIQQRA++P I+G+DVIAQA
Sbjct: 19 MDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQA 78
Query: 190 QSGTGKTATFSVAILQRIDVTKNEVQALVLAPTRELAKQIHKVIIALGDYMGAKSYACIG 369
QSGTGKTATF+++ILQ++++ E QALVLAPTRELA+QI KVI+ALGDYMGA +ACIG
Sbjct: 79 QSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIG 138
Query: 370 GTRVQEDVGNLE-NGVHVIVGTPGRVNDMIERGNLKTNSIKMFVLDEADEMLSRGFKEQI 546
GT V+ ++ L+ H++VGTPGRV DM+ R L IKMFVLDEAD MLSRGFK+QI
Sbjct: 139 GTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADGMLSRGFKDQI 198
Query: 547 HSVIQFIEHDTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNV 717
+ + Q + Q+VLLSATMP DVLEVT+KFMR P++ILVKKEELTLEGI+QFY+NV
Sbjct: 199 YEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINV 255
>sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 402
Score = 319 bits (818), Expect = 4e-87
Identities = 160/234 (68%), Positives = 192/234 (82%)
Frame = +1
Query: 22 GEIETNYEKVTESFDDMNLKEDLLRGIYAYGFEKPSAIQQRAVLPAIEGHDVIAQAQSGT 201
G IE NY++V ESFDDM LKE+LLRGIY +GFEKPSAIQ+RA++P G DVIAQAQSGT
Sbjct: 18 GLIEGNYDQVVESFDDMELKEELLRGIYGFGFEKPSAIQKRAIVPCTTGKDVIAQAQSGT 77
Query: 202 GKTATFSVAILQRIDVTKNEVQALVLAPTRELAKQIHKVIIALGDYMGAKSYACIGGTRV 381
GKTATFSV+ILQRID VQALV+APTRELA+QI KV+ ALG+Y+ CIGGT V
Sbjct: 78 GKTATFSVSILQRIDHEDPHVQALVMAPTRELAQQIQKVMSALGEYLNVNILPCIGGTSV 137
Query: 382 QEDVGNLENGVHVIVGTPGRVNDMIERGNLKTNSIKMFVLDEADEMLSRGFKEQIHSVIQ 561
++D LE G+HV+VGTPGRV DMI R L T+ IKMFVLDEADEMLSRGFK+QI+ V +
Sbjct: 138 RDDQRKLEAGIHVVVGTPGRVGDMINRNALDTSRIKMFVLDEADEMLSRGFKDQIYEVFR 197
Query: 562 FIEHDTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSE 723
+ D Q+VLLSATMP +VL+VT +FMR+P++ILVKK+ELTLEGIRQFY+NV +
Sbjct: 198 SMPQDVQVVLLSATMPSEVLDVTNRFMRNPIRILVKKDELTLEGIRQFYINVQK 251
>sp|P35683|IF4A_ORYSA Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 413
Score = 309 bits (791), Expect = 6e-84
Identities = 157/239 (65%), Positives = 192/239 (80%), Gaps = 3/239 (1%)
Frame = +1
Query: 16 NPGEIE---TNYEKVTESFDDMNLKEDLLRGIYAYGFEKPSAIQQRAVLPAIEGHDVIAQ 186
N GE E T+Y++V ESFDDM L+E+LLRGIYAYGFEKPSAIQQR ++P +G DVI Q
Sbjct: 25 NQGETEEFFTSYDEVHESFDDMGLQENLLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQ 84
Query: 187 AQSGTGKTATFSVAILQRIDVTKNEVQALVLAPTRELAKQIHKVIIALGDYMGAKSYACI 366
AQSGTGKTATF ILQ++D E QALVLAPTRELA+QI KV+ ALGDY+G K +AC+
Sbjct: 85 AQSGTGKTATFCSGILQQLDYAVVECQALVLAPTRELAQQIEKVMRALGDYLGVKVHACV 144
Query: 367 GGTRVQEDVGNLENGVHVIVGTPGRVNDMIERGNLKTNSIKMFVLDEADEMLSRGFKEQI 546
GGT V+ED L +GVHV+VGTPGRV DM+ R +L+ + IKMFVLDEADEMLSRGFK+QI
Sbjct: 145 GGTSVREDQRILASGVHVVVGTPGRVFDMLRRQSLRPDYIKMFVLDEADEMLSRGFKDQI 204
Query: 547 HSVIQFIEHDTQIVLLSATMPPDVLEVTRKFMRSPVKILVKKEELTLEGIRQFYVNVSE 723
+ + Q + Q+ + SATMPP+ LE+TRKFM PV+ILVK++ELTLEGI+QFYVNV +
Sbjct: 205 YDIFQLLPSKIQVGVFSATMPPEALEITRKFMNKPVRILVKRDELTLEGIKQFYVNVEK 263
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,488,846
Number of Sequences: 369166
Number of extensions: 1760739
Number of successful extensions: 4894
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4449
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4564
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6462248555
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)