Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_D11
(613 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P04694|ATTY_RAT Tyrosine aminotransferase (L-tyrosine:2-... 237 2e-62
sp|Q8QZR1|ATTY_MOUSE Tyrosine aminotransferase (L-tyrosine:... 237 2e-62
sp|P17735|ATTY_HUMAN Tyrosine aminotransferase (L-tyrosine:... 233 3e-61
sp|P33447|ATTY_TRYCR Tyrosine aminotransferase (L-tyrosine:... 135 1e-31
sp|P0A959|YFBQ_ECOLI Probable aminotransferase yfbQ >gi|711... 84 2e-16
sp|P71348|Y286_HAEIN Probable aminotransferase HI0286 82 1e-15
sp|Q60013|AAT_STRVG Aspartate aminotransferase (Transaminas... 77 3e-14
sp|P63499|AAT_MYCBO Probable aspartate aminotransferase (Tr... 76 6e-14
sp|Q60317|AAT1_METJA Probable aspartate aminotransferase 1 ... 72 9e-13
sp|P14909|AAT_SULSO Aspartate aminotransferase (Transaminas... 71 2e-12
>sp|P04694|ATTY_RAT Tyrosine aminotransferase (L-tyrosine:2-oxoglutarate
aminotransferase) (TAT)
Length = 454
Score = 237 bits (605), Expect = 2e-62
Identities = 108/193 (55%), Positives = 146/193 (75%)
Frame = +3
Query: 24 KKNFVIKASQMANNTLNPIRRMVDQLKLEPNPDKKMIPLSIGDPTIYGNLKCDDFVTEAV 203
K + ++ S M+N T NPIR +VD +K++PNP+K +I LSIGDPT++GNL D VT+A+
Sbjct: 38 KARWDVRPSDMSNKTFNPIRAIVDNMKVQPNPNKTVISLSIGDPTVFGNLPTDPEVTQAM 97
Query: 204 VEAVRSGKYNGYAPATGYEEARCAVAKYSNCSNYNLTSQDVLITSGCSSALEHCILVLAN 383
+A+ SGKYNGYAP+ GY +R VA Y +C L ++DV++TSGCS A+E C+ VLAN
Sbjct: 98 KDALDSGKYNGYAPSIGYLSSREEVASYYHCHEAPLEAKDVILTSGCSQAIELCLAVLAN 157
Query: 384 PGQNILVPKPGFPLYNTISHASGIKTKYYNLLPQNEWEVDLIHLESQIDNETVAILVNNP 563
PGQNIL+P+PGF LY T++ + GI+ K YNLLP+ WE+DL LES ID +T ++VNNP
Sbjct: 158 PGQNILIPRPGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKTACLVVNNP 217
Query: 564 SNPCGSVYSREHL 602
SNPCGSV+S+ HL
Sbjct: 218 SNPCGSVFSKRHL 230
>sp|Q8QZR1|ATTY_MOUSE Tyrosine aminotransferase (L-tyrosine:2-oxoglutarate
aminotransferase) (TAT)
Length = 454
Score = 237 bits (604), Expect = 2e-62
Identities = 108/193 (55%), Positives = 146/193 (75%)
Frame = +3
Query: 24 KKNFVIKASQMANNTLNPIRRMVDQLKLEPNPDKKMIPLSIGDPTIYGNLKCDDFVTEAV 203
K + ++ S M+N T NPIR +VD +K++PNP+K +I LSIGDPT++GNL D VT+A+
Sbjct: 38 KARWNVRPSDMSNKTFNPIRAIVDNMKVKPNPNKTVISLSIGDPTVFGNLPTDPEVTQAM 97
Query: 204 VEAVRSGKYNGYAPATGYEEARCAVAKYSNCSNYNLTSQDVLITSGCSSALEHCILVLAN 383
+A+ SGKYNGYAP+ GY +R VA Y +C L ++DV++TSGCS A+E C+ VLAN
Sbjct: 98 KDALDSGKYNGYAPSIGYLSSREEVASYYHCPEAPLEAKDVILTSGCSQAIELCLAVLAN 157
Query: 384 PGQNILVPKPGFPLYNTISHASGIKTKYYNLLPQNEWEVDLIHLESQIDNETVAILVNNP 563
PGQNIL+P+PGF LY T++ + GI+ K YNLLP+ WE+DL LES ID +T ++VNNP
Sbjct: 158 PGQNILIPRPGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKTACLVVNNP 217
Query: 564 SNPCGSVYSREHL 602
SNPCGSV+S+ HL
Sbjct: 218 SNPCGSVFSKRHL 230
>sp|P17735|ATTY_HUMAN Tyrosine aminotransferase (L-tyrosine:2-oxoglutarate
aminotransferase) (TAT)
Length = 454
Score = 233 bits (594), Expect = 3e-61
Identities = 106/193 (54%), Positives = 144/193 (74%)
Frame = +3
Query: 24 KKNFVIKASQMANNTLNPIRRMVDQLKLEPNPDKKMIPLSIGDPTIYGNLKCDDFVTEAV 203
K + ++ S MA T NPIR +VD +K++PNP+K MI LSIGDPT++GNL D VT+A+
Sbjct: 38 KARWSVRPSDMAKKTFNPIRAIVDNMKVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAM 97
Query: 204 VEAVRSGKYNGYAPATGYEEARCAVAKYSNCSNYNLTSQDVLITSGCSSALEHCILVLAN 383
+A+ SGKYNGYAP+ G+ +R +A Y +C L ++DV++TSGCS A++ C+ VLAN
Sbjct: 98 KDALDSGKYNGYAPSIGFLSSREEIASYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLAN 157
Query: 384 PGQNILVPKPGFPLYNTISHASGIKTKYYNLLPQNEWEVDLIHLESQIDNETVAILVNNP 563
PGQNILVP+PGF LY T++ + GI+ K YNLLP+ WE+DL LE ID +T ++VNNP
Sbjct: 158 PGQNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLIVNNP 217
Query: 564 SNPCGSVYSREHL 602
SNPCGSV+S+ HL
Sbjct: 218 SNPCGSVFSKRHL 230
>sp|P33447|ATTY_TRYCR Tyrosine aminotransferase (L-tyrosine:2-oxoglutarate
aminotransferase) (TAT)
Length = 416
Score = 135 bits (339), Expect = 1e-31
Identities = 77/198 (38%), Positives = 108/198 (54%), Gaps = 7/198 (3%)
Frame = +3
Query: 39 IKASQMANNTLNPIRRMVDQLKLEPNPDKKMIPLSIGDPTIYGNLKCDDFVTEAVVEAVR 218
+ S A NPIR + D K P+P K +I LS+GDPT+ NL + + EA+
Sbjct: 6 VSMSNHAGLVFNPIRTVSDNAKPSPSP-KPIIKLSVGDPTLDKNLLTSAAQIKKLKEAID 64
Query: 219 SGKYNGYAPATGYEEARCAVAKYSNCS-------NYNLTSQDVLITSGCSSALEHCILVL 377
S + NGY P G EAR AVA + S + +V++ SG S + I +
Sbjct: 65 SQECNGYFPTVGSPEAREAVATWWRNSFVHKEELKSTIVKDNVVLCSGGSHGILMAITAI 124
Query: 378 ANPGQNILVPKPGFPLYNTISHASGIKTKYYNLLPQNEWEVDLIHLESQIDNETVAILVN 557
+ G LVP+PGFP Y T+ A GI +YN P+N+WE DL + D++T ++V
Sbjct: 125 CDAGDYALVPQPGFPHYETVCKAYGIGMHFYNCRPENDWEADLDEIRRLKDDKTKLLIVT 184
Query: 558 NPSNPCGSVYSREHLIDI 611
NPSNPCGS +SR+H+ DI
Sbjct: 185 NPSNPCGSNFSRKHVEDI 202
>sp|P0A959|YFBQ_ECOLI Probable aminotransferase yfbQ
sp|P0A961|YFBQ_SHIFL Probable aminotransferase yfbQ
sp|P0A960|YFBQ_ECOL6 Probable aminotransferase yfbQ
Length = 405
Score = 84.3 bits (207), Expect = 2e-16
Identities = 57/195 (29%), Positives = 101/195 (51%), Gaps = 5/195 (2%)
Frame = +3
Query: 42 KASQMAN---NTLNPIRRMVDQLKLEPNPDKKMIPLSIGDPTIYGNLKCDDFVTEAVVEA 212
K+S++ N + P+ + +L+ E N K++ L+IG+P +G D E +V+
Sbjct: 6 KSSKLENVCYDIRGPVLKEAKRLEEEGN---KVLKLNIGNPAPFGF----DAPDEILVDV 58
Query: 213 VRS-GKYNGYAPATGYEEARCAVAKYSNCSNY-NLTSQDVLITSGCSSALEHCILVLANP 386
+R+ GY + G AR A+ ++ ++T +D+ I +G S + + L N
Sbjct: 59 IRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNS 118
Query: 387 GQNILVPKPGFPLYNTISHASGIKTKYYNLLPQNEWEVDLIHLESQIDNETVAILVNNPS 566
G +LVP P +PL+ S K +Y ++W DL + ++I T I++ NP+
Sbjct: 119 GDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDDIRAKITPRTRGIVIINPN 178
Query: 567 NPCGSVYSREHLIDI 611
NP G+VYS+E L++I
Sbjct: 179 NPTGAVYSKELLMEI 193
>sp|P71348|Y286_HAEIN Probable aminotransferase HI0286
Length = 404
Score = 81.6 bits (200), Expect = 1e-15
Identities = 55/191 (28%), Positives = 96/191 (50%), Gaps = 1/191 (0%)
Frame = +3
Query: 42 KASQMANNTLNPIRRMVDQLKLEPNPDKKMIPLSIGDPTIYGNLKCDDFVTEAVVEAVRS 221
K + + P+ + +L+ E N K++ L+IG+P +G D+ + + V+ + S
Sbjct: 9 KLEHVCYDIRGPVHKEALRLEEEGN---KILKLNIGNPAPFGFEAPDEILVD-VLRNLPS 64
Query: 222 GKYNGYAPATGYEEARCAVAKYSNCSNY-NLTSQDVLITSGCSSALEHCILVLANPGQNI 398
+ GY + G AR A+ +Y T DV I +G S + + L N G +
Sbjct: 65 AQ--GYCDSKGLYSARKAIVQYYQSKGILGATVNDVYIGNGVSELITMAMQALLNDGDEV 122
Query: 399 LVPKPGFPLYNTISHASGIKTKYYNLLPQNEWEVDLIHLESQIDNETVAILVNNPSNPCG 578
LVP P +PL+ SG K +Y W + ++++++ +T AI++ NP+NP G
Sbjct: 123 LVPMPDYPLWTAAVTLSGGKAVHYLCDEDANWFPTIDDIKAKVNAKTKAIVIINPNNPTG 182
Query: 579 SVYSREHLIDI 611
+VYS+E L +I
Sbjct: 183 AVYSKELLQEI 193
>sp|Q60013|AAT_STRVG Aspartate aminotransferase (Transaminase A) (ASPAT)
Length = 397
Score = 77.0 bits (188), Expect = 3e-14
Identities = 50/158 (31%), Positives = 77/158 (48%), Gaps = 2/158 (1%)
Frame = +3
Query: 123 KKMIPLSIGDPTIYGNLKCDDFVTEAVVEAVRSGKYNGYAPATGYEEARCAV-AKYSNCS 299
+ +I G+P + D++ EA VEA R+ KY+ Y PA G E + A+ AK S
Sbjct: 28 RPVIGFGAGEP----DFPTPDYIVEAAVEACRNPKYHRYTPAGGLPELKAAIAAKTLRDS 83
Query: 300 NYNLTSQDVLITSGCSSALEHCILVLANPGQNILVPKPGFPLY-NTISHASGIKTKYYNL 476
Y + + VL+T+G A+ + +PG ++VP P + Y +I A G+
Sbjct: 84 GYEVEASQVLVTNGGKQAIYEAFAAILDPGDEVIVPAPYWTTYPESIRLAGGVPVDVV-A 142
Query: 477 LPQNEWEVDLIHLESQIDNETVAILVNNPSNPCGSVYS 590
+ V + LE+ T +L +PSNP GSVYS
Sbjct: 143 DETTGYRVSVEQLEAARTERTKVVLFVSPSNPTGSVYS 180
>sp|P63499|AAT_MYCBO Probable aspartate aminotransferase (Transaminase A) (ASPAT)
sp|P63498|AAT_MYCTU Probable aspartate aminotransferase (Transaminase A) (ASPAT)
Length = 429
Score = 76.3 bits (186), Expect = 6e-14
Identities = 50/178 (28%), Positives = 91/178 (51%), Gaps = 2/178 (1%)
Frame = +3
Query: 75 PIRRMVDQLKLEPNPDKKMIPLSIGDPTIYGNLKCDDFVTEAVVEAVRSGKYNGYAPATG 254
P+ + +L+ E + +++ L+IG+P +G + D + +++A+ + GY+ + G
Sbjct: 44 PVHQHAARLEAEGH---RILKLNIGNPAPFG-FEAPDVIMRDIIQALPYAQ--GYSDSQG 97
Query: 255 YEEARCAVA-KYSNCSNY-NLTSQDVLITSGCSSALEHCILVLANPGQNILVPKPGFPLY 428
AR AV +Y + DV + +G S + + L + G +L+P P +PL+
Sbjct: 98 ILSARRAVVTRYELVPGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLW 157
Query: 429 NTISHASGIKTKYYNLLPQNEWEVDLIHLESQIDNETVAILVNNPSNPCGSVYSREHL 602
+ +G +Y W+ D+ LES+I T A++V NP+NP G+VYS E L
Sbjct: 158 TASTSLAGGTPVHYLCDETQGWQPDIADLESKITERTKALVVINPNNPTGAVYSCEIL 215
>sp|Q60317|AAT1_METJA Probable aspartate aminotransferase 1 (Transaminase A) (ASPAT)
Length = 375
Score = 72.4 bits (176), Expect = 9e-13
Identities = 47/156 (30%), Positives = 79/156 (50%), Gaps = 1/156 (0%)
Frame = +3
Query: 132 IPLSIGDPTIYGNLKCDDFVTEAVVEAVRSGKYNGYAPATGYEEARCAVA-KYSNCSNYN 308
I L IG+P + + EA A+ GK + Y+P G E R ++ K + N +
Sbjct: 26 INLGIGEP----DFDTPKHIIEAAKRALDEGKTH-YSPNNGIPELREEISNKLKDDYNLD 80
Query: 309 LTSQDVLITSGCSSALEHCILVLANPGQNILVPKPGFPLYNTISHASGIKTKYYNLLPQN 488
+ ++++T G S AL I+ L + G +L+P P F Y +++ + K K +L
Sbjct: 81 VDKDNIIVTCGASEALMLSIMTLIDRGDEVLIPNPSFVSYFSLTEFAEGKIKNIDL--DE 138
Query: 489 EWEVDLIHLESQIDNETVAILVNNPSNPCGSVYSRE 596
+ +DL ++ I +T I+ N+PSNP G VY +E
Sbjct: 139 NFNIDLEKVKESITKKTKLIIFNSPSNPTGKVYDKE 174
>sp|P14909|AAT_SULSO Aspartate aminotransferase (Transaminase A) (AspAT)
Length = 402
Score = 71.2 bits (173), Expect = 2e-12
Identities = 48/158 (30%), Positives = 78/158 (49%), Gaps = 3/158 (1%)
Frame = +3
Query: 126 KMIPLSIGDPTIYGNLKCDDFVTEAVVEAVRSGKYNGYAPATGYEEARCAVAKYSNCS-N 302
K+I IG P +L + +A EA+ G + Y A G +E R +A+Y N
Sbjct: 36 KIIDFGIGQP----DLPTFKRIRDAAKEALDQG-FTFYTSAFGIDELREKIAQYLNTRYG 90
Query: 303 YNLTSQDVLITSGCSSALEHCILVLANPGQNILVPKPGFPLYNTISHASGIKTKYYNLLP 482
++ ++V++T G AL ++ NP +++P P F Y + G K Y NL
Sbjct: 91 TDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDPSFYSYAEVVKLLGGKPIYANLKW 150
Query: 483 QNE--WEVDLIHLESQIDNETVAILVNNPSNPCGSVYS 590
E + +D+ L+S+I T I+ NNP NP G+++S
Sbjct: 151 SREEGFSIDVDDLQSKISKRTKMIVFNNPHNPTGTLFS 188
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,761,522
Number of Sequences: 369166
Number of extensions: 1438004
Number of successful extensions: 3970
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3818
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3904
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4797864890
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)