Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_C13
(488 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28648|CD63_RAT CD63 antigen (AD1 antigen) 73 3e-13
sp|Q9XSK2|CD63_BOVIN CD63 antigen 73 4e-13
sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen ... 72 7e-13
sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antige... 70 3e-12
sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen... 69 6e-12
sp|O60637|TSN3_HUMAN Tetraspanin-3 (Tspan-3) (Transmembrane... 67 3e-11
sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane... 66 4e-11
sp|Q28709|CD63_RABIT CD63 antigen 66 5e-11
sp|P41731|CD63_MOUSE CD63 antigen 65 1e-10
sp|Q9QY33|TSN3_MOUSE Tetraspanin-3 (Tspan-3) (Transmembrane... 64 1e-10
>sp|P28648|CD63_RAT CD63 antigen (AD1 antigen)
Length = 238
Score = 73.2 bits (178), Expect = 3e-13
Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 3/125 (2%)
Frame = +1
Query: 4 IQNEFSKAFQKIYGNDTTVTKT---VDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQLF 174
+++EFSK+FQK N T KT +D LQ+ +CCGA+ TDW + +
Sbjct: 111 VKSEFSKSFQKQMQNYLTDNKTATILDKLQKENKCCGASNYTDWERIPGMAKDR-----V 165
Query: 175 PSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAF 354
P SCC IT C + T GC+ + ++ + LV G LGIAF E+ ++ +
Sbjct: 166 PDSCCINITVGCGNDFKESTIHTQGCVETIAAWLRKNVLLVAGAALGIAFVEVLGIIFSC 225
Query: 355 CLCRN 369
CL ++
Sbjct: 226 CLVKS 230
>sp|Q9XSK2|CD63_BOVIN CD63 antigen
Length = 237
Score = 72.8 bits (177), Expect = 4e-13
Identities = 41/125 (32%), Positives = 62/125 (49%), Gaps = 3/125 (2%)
Frame = +1
Query: 4 IQNEFSKAFQ---KIYGNDTTVTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQLF 174
+++EF+K F+ K Y D +D +Q+ +CCGA TDW + T
Sbjct: 111 VRSEFNKDFRQQMKNYPKDNQTASILDKMQKDFECCGAANYTDW------EKILAVTNKV 164
Query: 175 PSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAF 354
P SCC IT C K T+GC+ K+ ++ + +V+ LGIAF EI +V A
Sbjct: 165 PDSCCVNITHNCGINFVVKDIHTEGCVEKIAAWLRKNVLVVVAAALGIAFVEILGIVLAC 224
Query: 355 CLCRN 369
CL ++
Sbjct: 225 CLVKS 229
>sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen 3 (CD151 antigen)
Length = 253
Score = 72.0 bits (175), Expect = 7e-13
Identities = 31/106 (29%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
Frame = +1
Query: 58 VTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQLFPSSCCDPITSPCWELGYDKKA 237
VT VD LQQ CCG+ DW S+W ++ + +++ P SCC + + C + +
Sbjct: 142 VTNAVDKLQQEFHCCGSNNSRDWRDSEWIRSGEADSRVVPDSCCKTVVTGCGKREHASNI 201
Query: 238 F--TDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 369
+ GCI K+ S+ + + ++ + +GIA ++F ++ CL R+
Sbjct: 202 YKVEGGCITKLESFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane
glycoprotein SFA-1) (CD151 antigen) (Tetraspanin-24)
(Tspan-24)
Length = 253
Score = 69.7 bits (169), Expect = 3e-12
Identities = 30/106 (28%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = +1
Query: 58 VTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQLFPSSCCDPITSPCWELGYDKKA 237
VT VD LQQ CCG+ DW S+W ++ + ++ P SCC + + C + +
Sbjct: 142 VTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQRDHASNI 201
Query: 238 F--TDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 369
+ GCI K+ ++ + + ++ + +GIA ++F ++ CL R+
Sbjct: 202 YKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane
glycoprotein SFA-1) (CD151 antigen)
Length = 253
Score = 68.9 bits (167), Expect = 6e-12
Identities = 29/106 (27%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
Frame = +1
Query: 58 VTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQLFPSSCCDPITSPCWELGYDKKA 237
V+ VD LQQ CCG+ DW S+W ++ + +++ P SCC + + C + +
Sbjct: 142 VSSAVDKLQQEFHCCGSNNSQDWQDSEWIRSGEADSRVVPDSCCKTMVAGCGKRDHASNI 201
Query: 238 F--TDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 369
+ GCI K+ ++ + + ++ + +GIA ++F ++ CL R+
Sbjct: 202 YKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|O60637|TSN3_HUMAN Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8)
(Tetraspanin TM4-A)
Length = 253
Score = 66.6 bits (161), Expect = 3e-11
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 7/130 (5%)
Frame = +1
Query: 4 IQNEFSKAFQKIYG-----NDTTVTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQ 168
++NE ++ QK+Y N ++ +D +Q+ + CCG +DW +DW++ +KN Q
Sbjct: 111 VENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKN--Q 168
Query: 169 LFPSSCCDPITSPC-WELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVV 345
P SCC S C L + + +GC + + VI L A ++ ++
Sbjct: 169 SVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGML 228
Query: 346 CA-FCLCRNT 372
CA LCR +
Sbjct: 229 CACIVLCRRS 238
>sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6)
(T245 protein) (Tetraspanin TM4-D) (A15 homolog)
Length = 245
Score = 66.2 bits (160), Expect = 4e-11
Identities = 34/126 (26%), Positives = 57/126 (45%)
Frame = +1
Query: 7 QNEFSKAFQKIYGNDTTVTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQLFPSSC 186
+N + KA ++ + VD +Q + CCG T DW +++Y FP SC
Sbjct: 123 KNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKG-----FPKSC 177
Query: 187 CDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCR 366
C C K +GC K+ + ++ +V GI+ G+A F++ + A+CL R
Sbjct: 178 CK--LEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSR 235
Query: 367 NTVQHQ 384
+Q
Sbjct: 236 AITNNQ 241
>sp|Q28709|CD63_RABIT CD63 antigen
Length = 238
Score = 65.9 bits (159), Expect = 5e-11
Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 3/125 (2%)
Frame = +1
Query: 4 IQNEFSKAFQKIYGNDTTVTKT---VDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQLF 174
+ +EF+K F++ N +T +T +D +Q+ CCGA TDW +
Sbjct: 111 VMSEFNKDFRQQMQNYSTDNQTALILDRMQKDFTCCGAANYTDWATIPGMTRDR-----V 165
Query: 175 PSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAF 354
P SCC +TS C K + +GC+ K+ + + +V LGIAF E+ +V A
Sbjct: 166 PDSCCVNVTSGCGVKFNVKDIYVEGCVEKIGLWLRKNVLVVAAAALGIAFVEVLGIVFAC 225
Query: 355 CLCRN 369
CL ++
Sbjct: 226 CLVKS 230
>sp|P41731|CD63_MOUSE CD63 antigen
Length = 238
Score = 64.7 bits (156), Expect = 1e-10
Identities = 37/125 (29%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
Frame = +1
Query: 4 IQNEFSKAFQKIYGN---DTTVTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQLF 174
+++EF+K+FQ+ N D +D LQ+ CCGA+ TDW +
Sbjct: 111 VKSEFNKSFQQQMQNYLKDNKTATILDKLQKENNCCGASNYTDWENIPGMAKDR-----V 165
Query: 175 PSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAF 354
P SCC IT C + T GC+ + + + LV LGIAF E+ ++ +
Sbjct: 166 PDSCCINITVGCGNDFKESTIHTQGCVETIAIWLRKNILLVAAAALGIAFVEVLGIIFSC 225
Query: 355 CLCRN 369
CL ++
Sbjct: 226 CLVKS 230
>sp|Q9QY33|TSN3_MOUSE Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8)
(Tetraspanin TM4-A) (OSP-associated protein 1) (OAP-1)
Length = 253
Score = 64.3 bits (155), Expect = 1e-10
Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 7/130 (5%)
Frame = +1
Query: 4 IQNEFSKAFQKIYG-----NDTTVTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQ 168
++NE ++ QK+Y N ++ +D +Q+ + CCG +DW +DW++ +KN Q
Sbjct: 111 VENEVDRSIQKVYKTYNGTNSDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKN--Q 168
Query: 169 LFPSSCCDPITSPC-WELGYDKKAFTDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVV 345
P SCC C L + +GC + + VI L A ++ ++
Sbjct: 169 SVPLSCCRETAKSCNGSLANPSDLYAEGCEALVVKKLQEILMHVIWAALAFAAIQLLGML 228
Query: 346 CA-FCLCRNT 372
CA LCR +
Sbjct: 229 CACIVLCRRS 238
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,219,047
Number of Sequences: 369166
Number of extensions: 1123688
Number of successful extensions: 2860
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2764
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2829
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2970720600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)