Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_C04
(647 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P50990|TCPQ_HUMAN T-complex protein 1, theta subunit (TC... 169 6e-42
sp|P42932|TCPQ_MOUSE T-complex protein 1, theta subunit (TC... 169 7e-42
sp|P47828|TCPQ_CANAL T-complex protein 1, theta subunit (TC... 116 4e-26
sp|P78921|TCPQ_SCHPO Probable T-complex protein 1, theta su... 113 4e-25
sp|Q58405|THS_METJA Thermosome subunit (Chaperonin subunit) 103 5e-22
sp|O26885|THSB_METTH Thermosome beta subunit (Thermosome su... 102 7e-22
sp|P47079|TCPQ_YEAST T-complex protein 1, theta subunit (TC... 101 1e-21
sp|O93624|THS_METTL Thermosome subunit (Chaperonin subunit) 99 1e-20
sp|P80315|TCPD_MOUSE T-complex protein 1, delta subunit (TC... 98 2e-20
sp|Q7TPB1|TCPD_RAT T-complex protein 1, delta subunit (TCP-... 98 2e-20
>sp|P50990|TCPQ_HUMAN T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
sp|Q5RAP1|TCPQ_PONPY T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 548
Score = 169 bits (428), Expect = 6e-42
Identities = 86/167 (51%), Positives = 118/167 (70%)
Frame = +2
Query: 11 VVLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIEL 190
VV+F + ++GAIS+IV+RGS ++MD++ERA+DDGVNTFK LT++ R + G GATEIEL
Sbjct: 360 VVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIEL 419
Query: 191 ANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFG 370
A +++ + T GL QYAIK+F AFE+I + L +N+G A E I++L A H+EG G
Sbjct: 420 AKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVG 479
Query: 371 IISTSEGRKVDDAVEHQILDTYTAKYWGIRFAADTAVTILRVDNIIM 511
+ +E V D +E ILDTY KYW I+ A + AVT+LRVD IIM
Sbjct: 480 LDIEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIM 526
>sp|P42932|TCPQ_MOUSE T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 548
Score = 169 bits (427), Expect = 7e-42
Identities = 85/167 (50%), Positives = 118/167 (70%)
Frame = +2
Query: 11 VVLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIEL 190
VV+F + ++GAIS+IV+RGS ++MD++ERA+DDGVNTFK LT++ R + G GATEIEL
Sbjct: 360 VVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIEL 419
Query: 191 ANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFG 370
A +++ + T GL QYAIK+F AFE+I + L +N+G A E I++L + H+EG G
Sbjct: 420 AKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYSVHQEGNKNVG 479
Query: 371 IISTSEGRKVDDAVEHQILDTYTAKYWGIRFAADTAVTILRVDNIIM 511
+ +E V D +E ILDTY KYW I+ A + AVT+LRVD IIM
Sbjct: 480 LDIEAEVPAVKDMLEASILDTYLGKYWAIKLATNAAVTVLRVDQIIM 526
>sp|P47828|TCPQ_CANAL T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 540
Score = 116 bits (291), Expect = 4e-26
Identities = 71/167 (42%), Positives = 96/167 (57%)
Frame = +2
Query: 11 VVLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIEL 190
V +F QD ++IVVRG+ + +D++ERAIDDGVN+ K L K+ R L GAGA EIEL
Sbjct: 357 VTIFRQDESSSRTATIVVRGATQNNLDDIERAIDDGVNSIKGLIKDNRLLPGAGAVEIEL 416
Query: 191 ANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFG 370
R++ + +T GL+Q AIK F AFE I +VL + +G +++E +++L A H E
Sbjct: 417 MKRITAYQST-PGLLQLAIKSFAKAFEVIPRVLAETSGHDSSEILSKLHAAHAEDTGLRA 475
Query: 371 IISTSEGRKVDDAVEHQILDTYTAKYWGIRFAADTAVTILRVDNIIM 511
I G D AV LD K I A D TIL +D IIM
Sbjct: 476 GIDIDSGEVADTAV----LDILATKKSAIDLAVDATNTILSIDQIIM 518
>sp|P78921|TCPQ_SCHPO Probable T-complex protein 1, theta subunit (TCP-1-theta)
(CCT-theta)
Length = 546
Score = 113 bits (283), Expect = 4e-25
Identities = 65/168 (38%), Positives = 98/168 (58%), Gaps = 1/168 (0%)
Frame = +2
Query: 11 VVLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIEL 190
V +F Q ++IV+RG+ +D++ERAIDDGVN K L K+ R + GAGA++++L
Sbjct: 360 VTVFRQVEDITRTATIVLRGATKTYLDDLERAIDDGVNIVKALVKDNRLIFGAGASDMQL 419
Query: 191 ANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAEL-KAHHREGKTTF 367
RL G+ Q+AIKQ+ AFE + + + +NAG + T+ I++L AHH+E +
Sbjct: 420 CIRLISVGEKTPGIYQHAIKQYGEAFEVVPRTISENAGLDPTDVISKLYAAHHKENGESI 479
Query: 368 GIISTSEGRKVDDAVEHQILDTYTAKYWGIRFAADTAVTILRVDNIIM 511
G+ E DA E I D AK IR A +T +T+L VD ++M
Sbjct: 480 GVDVECENDGTLDAKEAGIFDVLLAKKSAIRLATETVLTVLNVDQVVM 527
>sp|Q58405|THS_METJA Thermosome subunit (Chaperonin subunit)
Length = 542
Score = 103 bits (256), Expect = 5e-22
Identities = 60/166 (36%), Positives = 96/166 (57%), Gaps = 1/166 (0%)
Frame = +2
Query: 14 VLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELA 193
++F + K +I+ RGS +++EV RAIDD + KC +E + +AG GATEIELA
Sbjct: 357 MIFVEQCKHPKAVTILARGSTEHVVEEVARAIDDAIGVVKCALEEGKIVAGGGATEIELA 416
Query: 194 NRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELK-AHHREGKTTFG 370
RL FA + G Q A+K F A E I + L +N+G + + + +L+ AH +EG +G
Sbjct: 417 KRLRKFAESVAGREQLAVKAFADALEVIPRTLAENSGLDPIDMLVKLRAAHEKEGGEVYG 476
Query: 371 IISTSEGRKVDDAVEHQILDTYTAKYWGIRFAADTAVTILRVDNII 508
+ EG +V D +E +++ K I A + +V +LR+D++I
Sbjct: 477 -LDVFEG-EVVDMLEKGVVEPLKVKTQAIDSATEASVMLLRIDDVI 520
>sp|O26885|THSB_METTH Thermosome beta subunit (Thermosome subunit 2) (Chaperonin beta
subunit)
Length = 538
Score = 102 bits (255), Expect = 7e-22
Identities = 58/165 (35%), Positives = 99/165 (60%)
Frame = +2
Query: 14 VLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELA 193
++F ++ KE +I+VRGS ++ EVERAI+D + ++ + +AG GA EIE+A
Sbjct: 353 MIFVEECKEPKAVTILVRGSTEHVVSEVERAIEDAIGVVAATVEDGKVVAGGGAPEIEIA 412
Query: 194 NRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGI 373
RL D+A++ +G Q A+ F A E + K L +NAG ++ + + +L+A H E +T+
Sbjct: 413 KRLKDYADSISGREQLAVSAFAEALEIVPKTLAENAGLDSIDVLVDLRAAHEE--STYMG 470
Query: 374 ISTSEGRKVDDAVEHQILDTYTAKYWGIRFAADTAVTILRVDNII 508
I +G K+ D E +++ + K I+ AA+ A ILR+D++I
Sbjct: 471 IDVFDG-KIVDMKEAGVIEPHRVKKQAIQSAAEAAEMILRIDDVI 514
>sp|P47079|TCPQ_YEAST T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)
Length = 568
Score = 101 bits (252), Expect = 1e-21
Identities = 68/181 (37%), Positives = 95/181 (52%), Gaps = 14/181 (7%)
Frame = +2
Query: 11 VVLFDQDVKE-GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEP--RYLAGAGATE 181
V +F Q+ E S+I++RG+ + +D++ERAIDDGV K L K + L GAGATE
Sbjct: 368 VTVFKQEQGEISRTSTIILRGATQNNLDDIERAIDDGVAAVKGLMKPSGGKLLPGAGATE 427
Query: 182 IELANRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKT 361
IEL +R++ + GL+Q AIKQF +AFE + + L + AG + E + L A H T
Sbjct: 428 IELISRITKYGERTPGLLQLAIKQFAVAFEVVPRTLAETAGLDVNEVLPNLYAAH--NVT 485
Query: 362 TFGIISTSEGRK-----------VDDAVEHQILDTYTAKYWGIRFAADTAVTILRVDNII 508
G + T K V D E I D K + I A + A T+L +D II
Sbjct: 486 EPGAVKTDHLYKGVDIDGESDEGVKDIREENIYDMLATKKFAINVATEAATTVLSIDQII 545
Query: 509 M 511
M
Sbjct: 546 M 546
>sp|O93624|THS_METTL Thermosome subunit (Chaperonin subunit)
Length = 544
Score = 98.6 bits (244), Expect = 1e-20
Identities = 50/165 (30%), Positives = 95/165 (57%)
Frame = +2
Query: 14 VLFDQDVKEGAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELA 193
++F ++ K ++++RG+ +++EV RA+DD + C ++ + +AG GA EIELA
Sbjct: 355 MIFVEECKHPKAVTMLIRGTTEHVIEEVARAVDDAIGVVACTIEDGKIVAGGGAAEIELA 414
Query: 194 NRLSDFANTQTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGI 373
+L D+A +G Q A++ F A E + + L +NAG +A E + +L+A H EG +
Sbjct: 415 MKLRDYAEGVSGREQLAVRAFADALEVVPRTLAENAGLDAIEMLVKLRAKHAEGNNAYYG 474
Query: 374 ISTSEGRKVDDAVEHQILDTYTAKYWGIRFAADTAVTILRVDNII 508
++ G V++ E+ +++ K I+ A + +LR+D++I
Sbjct: 475 LNVFTG-DVENMTENGVVEPLRVKTQAIQSATEATEMLLRIDDVI 518
>sp|P80315|TCPD_MOUSE T-complex protein 1, delta subunit (TCP-1-delta) (CCT-delta) (A45)
Length = 539
Score = 98.2 bits (243), Expect = 2e-20
Identities = 52/156 (33%), Positives = 87/156 (55%)
Frame = +2
Query: 41 GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANT 220
G +IVVRGS +++E ER+I D + +CL K+ +AG GA EIELA RL++++ T
Sbjct: 383 GKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRT 442
Query: 221 QTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGRKV 400
+G+ Y ++ F A E I L +NAG N + EL+ H +G+ T GI G +
Sbjct: 443 LSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTTGINVRKGG--I 500
Query: 401 DDAVEHQILDTYTAKYWGIRFAADTAVTILRVDNII 508
+ +E ++ + A +T +IL++D+++
Sbjct: 501 SNILEEMVVQPLLVSVSALTLATETVRSILKIDDVV 536
>sp|Q7TPB1|TCPD_RAT T-complex protein 1, delta subunit (TCP-1-delta) (CCT-delta)
Length = 539
Score = 98.2 bits (243), Expect = 2e-20
Identities = 52/156 (33%), Positives = 87/156 (55%)
Frame = +2
Query: 41 GAISSIVVRGSMYDMMDEVERAIDDGVNTFKCLTKEPRYLAGAGATEIELANRLSDFANT 220
G +IVVRGS +++E ER+I D + +CL K+ +AG GA EIELA RL++++ T
Sbjct: 383 GKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRT 442
Query: 221 QTGLVQYAIKQFVLAFESIVKVLCDNAGENATERIAELKAHHREGKTTFGIISTSEGRKV 400
+G+ Y ++ F A E I L +NAG N + EL+ H +G+ T GI G +
Sbjct: 443 LSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTTGINVRKGG--I 500
Query: 401 DDAVEHQILDTYTAKYWGIRFAADTAVTILRVDNII 508
+ +E ++ + A +T +IL++D+++
Sbjct: 501 SNILEEMVVQPLLVSVSALTLATETVRSILKIDDVV 536
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,523,522
Number of Sequences: 369166
Number of extensions: 1409279
Number of successful extensions: 3945
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3773
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3917
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5316264630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)