Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_C02
(933 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P46504|YLX8_CAEEL Hypothetical protein F23F12.8 in chrom... 42 0.002
sp|Q9NQS7|INCE_HUMAN Inner centromere protein 41 0.004
sp|P13392|MYSP_DIRIM Paramyosin 41 0.006
sp|Q9NJA9|MYSP_ANISI Paramyosin (Allergen Ani s 2) 40 0.012
sp|Q01202|MYSP_BRUMA Paramyosin 39 0.016
sp|Q02171|MYSP_ONCVO Paramyosin 39 0.027
sp|P08089|M6B_STRP6 M protein, serotype 6 precursor 39 0.027
sp|P24788|CD2L1_MOUSE PITSLRE serine/threonine-protein kina... 38 0.047
sp|P21127|CD2L1_HUMAN PITSLRE serine/threonine-protein kina... 38 0.047
sp|Q01397|DYNA_NEUCR Dynactin, 150 kDa isoform (150 kDa dyn... 38 0.047
>sp|P46504|YLX8_CAEEL Hypothetical protein F23F12.8 in chromosome III precursor
Length = 887
Score = 42.0 bits (97), Expect = 0.002
Identities = 66/305 (21%), Positives = 120/305 (39%), Gaps = 25/305 (8%)
Frame = +1
Query: 91 RQIGIDKQALDQQVKDKKERECTERNVELAYA--------SDSIRNDLIATLLSKRQQDD 246
RQ +D+QA + ++ER ERN EL ++ +R + IA +SK
Sbjct: 349 RQAELDRQAT---IYAEQERMAMERNRELERIRLEEKKRENERVRQEEIAMEISK----- 400
Query: 247 IRELNKILNEFRA----FHQQPETRREWDLYDPDALKKDKPARVCDDDPRCGISSMQKFD 414
IREL ++ E + Q+ E R++ L + + +K + QK +
Sbjct: 401 IRELERLQLERQRKNERVRQELEAARKYKLQEEERQRKIQ---------------QQKVE 445
Query: 415 GEDLNNKARTKYQKEQMNDWNERQKADKERAEQAQKEADRLYDL----------KRREMD 564
E + + + +EQ+ E + + ER Q + E ++ K+ E D
Sbjct: 446 MEQIRQQEEAR--QEQLRVLEEERARELERVRQEELERQHQMEILRQQEEDQKKKKLEKD 503
Query: 565 ERACDLAAAEEACRRAMNMANSQYNVALFNEMNERARLKKQQENDDTLTAMANALYSD-- 738
+ AEE R + + + E N+R L+K+ E+ NA+Y +
Sbjct: 504 REQREQQEAEELNRMIIEKEMKENKQKMIEEKNKRKMLEKEMED------RQNAIYEEEE 557
Query: 739 -LLTENPAQATSSFGPGRVIPDRFKGMTPEQLNEIYKQQEDQMKDNKRRQMEEDLRNEEW 915
+ E + R I + T E+ ++E +M R+ E + + +E
Sbjct: 558 RRIAEEERRKQIEIEERRRIQQQIMIATEERSRLDAMEREREM---LRQIKESEKQRKEL 614
Query: 916 DRQRL 930
+RQ L
Sbjct: 615 ERQEL 619
>sp|Q9NQS7|INCE_HUMAN Inner centromere protein
Length = 919
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/221 (21%), Positives = 91/221 (41%), Gaps = 2/221 (0%)
Frame = +1
Query: 127 QVKDKKERECTERNVELAYASDSIRNDLIATLLSKRQQDDIRELNKILNEFRAFHQQPET 306
Q+ +K E+ ER E + + ++Q++D R L R Q+ E
Sbjct: 601 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEDARRL-------RWLQQEEEE 653
Query: 307 RREWDLYDPDALKKDKPARVCDDDPRCGISSMQ-KFDGEDLNNKARTKYQKEQMNDWNER 483
RR +L ++ + R + R Q + + E + R + ++EQ ER
Sbjct: 654 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 713
Query: 484 QKADKERAEQ-AQKEADRLYDLKRREMDERACDLAAAEEACRRAMNMANSQYNVALFNEM 660
++ +++ AEQ ++E +RL RE+ ER L +E +R + + +
Sbjct: 714 REQERQLAEQERRREQERLQ--AERELQEREKALRLQKEQLQRELEEKKKKEEQ---QRL 768
Query: 661 NERARLKKQQENDDTLTAMANALYSDLLTENPAQATSSFGP 783
ER ++Q++ + AL + ++PA +S P
Sbjct: 769 AERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSSPITP 809
>sp|P13392|MYSP_DIRIM Paramyosin
Length = 848
Score = 40.8 bits (94), Expect = 0.006
Identities = 69/302 (22%), Positives = 125/302 (41%), Gaps = 37/302 (12%)
Frame = +1
Query: 109 KQALDQQVKDKKERECTERNVELAYASDSIRNDLIATLLSKRQQDDIRELNKILNEFRAF 288
K+AL ++ K K + + E LA A+ + L + R +IREL L E A
Sbjct: 400 KEALARENK-KLQDDLHEAKEALADANRKLHE---LDLENARLAGEIRELQTALKESEAA 455
Query: 289 HQQPETRREWDLYDPDALKKDKPARVCDDDPRC-GISSMQKFDGEDLN------------ 429
+ E R + L + L+ + R+ + + + +F+ + L
Sbjct: 456 RRDAENRAQRALAELQQLRIEMERRLQEKEEEMEALRKNMQFEIDRLTAALADAEARMKA 515
Query: 430 --NKARTKYQKE---------QMNDWN-ERQKADKERAEQAQKEADRLYDLKRR---EMD 564
++ + KYQ E +N N E QK K+++EQ + L D +R+ +D
Sbjct: 516 EISRLKKKYQAEIAELEMTVDNLNRANIEAQKTIKKQSEQLKILQASLEDTQRQLQQTLD 575
Query: 565 ERACD------LAAAEEACRRAMNMANSQYNVALFNEMNERARLKKQQENDDTLTAMANA 726
+ A L+A E C+ A++ A A + AR+ ++ LTA+ N
Sbjct: 576 QYALAQRKVSALSAELEECKVALDNAIRARKQAEIDLEEANARITDLVSINNNLTAIKNK 635
Query: 727 LYSDLLTENP--AQATSSFGPGRVIPDRFKGMTPEQLNEIYKQQEDQMK-DNKRRQMEED 897
L ++L T +AT +R + +++++QE MK D R+ +EE
Sbjct: 636 LETELSTAQADLDEATKELHAADERANRALADAARAVEQLHEEQEHSMKIDALRKSLEEQ 695
Query: 898 LR 903
++
Sbjct: 696 VK 697
>sp|Q9NJA9|MYSP_ANISI Paramyosin (Allergen Ani s 2)
Length = 869
Score = 39.7 bits (91), Expect = 0.012
Identities = 68/302 (22%), Positives = 122/302 (40%), Gaps = 37/302 (12%)
Frame = +1
Query: 109 KQALDQQVKDKKERECTERNVELAYASDSIRNDLIATLLSKRQQDDIRELNKILNEFRAF 288
K+AL ++ K K + + E N LA A+ + L + R +IR+L L E A
Sbjct: 421 KEALARENK-KLQDDLHEANEALADANRKLHE---LDLENARLAGEIRDLQVALKESEAA 476
Query: 289 HQQPETRREWDLYDPDALKKDKPARVCDDDPRC-GISSMQKFDGEDLNN----------- 432
+ E R + L + ++ + R+ + + + +F+ + L
Sbjct: 477 RRDAEARAQRALAELQQVRIEMERRLQEKEEEMEALRKSMQFEIDRLTAALADAEARMKA 536
Query: 433 ---KARTKYQKE---------QMNDWN-ERQKADKERAEQAQKEADRLYDLKRR---EMD 564
+ R KYQ E +N N E QK K+++EQ + L D +R+ +D
Sbjct: 537 EIARLRKKYQAEIAELEMTVDNLNRANLEAQKTIKKQSEQIIQLQANLEDTQRQLQQTLD 596
Query: 565 ERACD------LAAAEEACRRAMNMANSQYNVALFNEMNERARLKKQQENDDTLTAMANA 726
+ A L+A E C+ A++ A A + R+ + LTA+ N
Sbjct: 597 QYALAQRKISALSAELEECKTALDNAIRARKQAEADLEEAHVRISDLTSINSNLTAIKNK 656
Query: 727 LYSDLLTENP--AQATSSFGPGRVIPDRFKGMTPEQLNEIYKQQEDQMK-DNKRRQMEED 897
L ++L T + T +R + E++++QE MK D R+ +EE
Sbjct: 657 LETELSTAQADLDEVTKELHAADERANRALADAARAVQELHEEQEHSMKIDALRKSLEEQ 716
Query: 898 LR 903
++
Sbjct: 717 VK 718
>sp|Q01202|MYSP_BRUMA Paramyosin
Length = 880
Score = 39.3 bits (90), Expect = 0.016
Identities = 68/302 (22%), Positives = 124/302 (41%), Gaps = 37/302 (12%)
Frame = +1
Query: 109 KQALDQQVKDKKERECTERNVELAYASDSIRNDLIATLLSKRQQDDIRELNKILNEFRAF 288
K+AL ++ K K + + E LA A+ + L + R +IREL L E A
Sbjct: 427 KEALARENK-KLQDDLHEAKEALADANRKLHE---LDLENARLAGEIRELQTALKESEAA 482
Query: 289 HQQPETRREWDLYDPDALKKDKPARVCDDDPRC-GISSMQKFDGEDLN------------ 429
+ E R + L + L+ + R+ + + + +F+ + L
Sbjct: 483 RRDAENRAQRALAELQQLRIEMERRLQEKEEEMEALRKNMQFEIDRLTAALADAEARMKA 542
Query: 430 --NKARTKYQKE---------QMNDWN-ERQKADKERAEQAQKEADRLYDLKRR---EMD 564
++ + KYQ E +N N E QK K+++EQ + L D +R+ +D
Sbjct: 543 EISRLKKKYQAEIAELEMTVDNLNRANIEAQKTIKKQSEQLKILQASLEDTQRQLQQTLD 602
Query: 565 ERACD------LAAAEEACRRAMNMANSQYNVALFNEMNERARLKKQQENDDTLTAMANA 726
+ A L+A E C+ A++ A A + R+ ++ LTA+ N
Sbjct: 603 QYALAQRKVSALSAELEECKVALDNAIRARKQAEIDLEEANGRITDLVSVNNNLTAIKNK 662
Query: 727 LYSDLLTENP--AQATSSFGPGRVIPDRFKGMTPEQLNEIYKQQEDQMK-DNKRRQMEED 897
L ++L T +AT +R + +++++QE MK D R+ +EE
Sbjct: 663 LETELSTAQADLDEATKELHAADERANRALADAARAVEQLHEEQEHSMKIDALRKSLEEQ 722
Query: 898 LR 903
++
Sbjct: 723 VK 724
>sp|Q02171|MYSP_ONCVO Paramyosin
Length = 879
Score = 38.5 bits (88), Expect = 0.027
Identities = 68/302 (22%), Positives = 123/302 (40%), Gaps = 37/302 (12%)
Frame = +1
Query: 109 KQALDQQVKDKKERECTERNVELAYASDSIRNDLIATLLSKRQQDDIRELNKILNEFRAF 288
K+AL ++ K K + + E LA A+ + L + R +IREL L E A
Sbjct: 427 KEALARENK-KLQDDLHEAKEALADANRKLHE---LDLENARLAGEIRELQTALKESEAA 482
Query: 289 HQQPETRREWDLYDPDALKKDKPARVCDDDPRC-GISSMQKFDGEDLNN----------- 432
+ E R + L + L+ + R+ + + + +F+ + L
Sbjct: 483 RRDAENRAQRALAELQQLRIEMERRLQEKEEEMEALRKNMQFEIDRLTAALADAEARMKA 542
Query: 433 ---KARTKYQKE---------QMNDWN-ERQKADKERAEQAQKEADRLYDLKRR---EMD 564
+ + KYQ E +N N E QK K+++EQ + L D +R+ +D
Sbjct: 543 EIARLKKKYQAEIAELEMTVDNLNRANIEAQKTIKKQSEQLKVLQASLEDTQRQLQQTLD 602
Query: 565 ERACD------LAAAEEACRRAMNMANSQYNVALFNEMNERARLKKQQENDDTLTAMANA 726
+ A L+A E C+ A++ A A + R+ ++ LTA+ N
Sbjct: 603 QYALAQRKVSALSAELEECKVALDNAIRARKQAEIDLEEANGRITDLVSINNNLTAIKNK 662
Query: 727 LYSDLLTENP--AQATSSFGPGRVIPDRFKGMTPEQLNEIYKQQEDQMK-DNKRRQMEED 897
L ++L T +AT +R + +++++QE MK D R+ +EE
Sbjct: 663 LETELSTAQADLDEATKELHAADERANRALADAARAVEQLHEEQEHSMKIDALRKSLEEQ 722
Query: 898 LR 903
++
Sbjct: 723 VK 724
>sp|P08089|M6B_STRP6 M protein, serotype 6 precursor
Length = 483
Score = 38.5 bits (88), Expect = 0.027
Identities = 78/296 (26%), Positives = 118/296 (39%), Gaps = 34/296 (11%)
Frame = +1
Query: 97 IGIDKQALDQQVKDK--KERECTERNVELAYASDSIRNDLIATLLSKRQQDDIRELNKIL 270
IG K+ LD+ VKDK KE+E E L D D IA + ++ I L K L
Sbjct: 162 IGTLKKTLDETVKDKIAKEQESKETIGTLKKTLDETVKDKIAK--EQESKETIGTLKKTL 219
Query: 271 NEF--RAFHQQPETRREWDLYDP--DALKKDKPARVCDDDPRCGISSMQKFDGEDLNNKA 438
+E ++ E++ D KDK AR G + Q+ +D NK
Sbjct: 220 DETVKDKIAKEQESKETIGTLKKILDETVKDKIAREQKSKQDIG-ALKQELAKKDEGNKV 278
Query: 439 RTKYQKEQMNDWNERQKADKERAEQAQ---------KEADRLYDLKRREMDERACDLAAA 591
+K D + ++A K+ + KE ++ D R+ + DL A+
Sbjct: 279 SEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRR---DLDAS 335
Query: 592 EEA---CRRAMNMANSQYNV--ALFNEMNERARL--KKQQENDDTLTAMANALYSDLLTE 750
EA +A+ ANS+ L E+ E +L K++ E L A A AL L +
Sbjct: 336 REAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQ 395
Query: 751 -------NPAQATSSFGP-----GRVIPDRFKGMTPEQLNEIYKQQEDQMKDNKRR 882
+A+ S P +V+P KG P Q Q + MK+ KR+
Sbjct: 396 AEELAKLRAGKASDSQTPDAKPGNKVVPG--KGQAP-QAGTKPNQNKAPMKETKRQ 448
>sp|P24788|CD2L1_MOUSE PITSLRE serine/threonine-protein kinase CDC2L1
(Galactosyltransferase-associated protein kinase
p58/GTA) (Cell division cycle 2-like protein kinase 1)
Length = 784
Score = 37.7 bits (86), Expect = 0.047
Identities = 40/177 (22%), Positives = 81/177 (45%), Gaps = 11/177 (6%)
Frame = +1
Query: 73 IFNSKTRQIGIDKQALDQQVKDKKERECTERNVELAYASD-----SIRNDLIA---TLLS 228
I K R+ +++A +++K+ +R+ ++E D +IRN ++
Sbjct: 16 ILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMED 75
Query: 229 KRQQDD---IRELNKILNEFRAFHQQPETRREWDLYDPDALKKDKPARVCDDDPRCGISS 399
+ ++DD I+ ++ + +A H++ E R+E + + + K ARV
Sbjct: 76 RGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGKHARV----------- 124
Query: 400 MQKFDGEDLNNKARTKYQKEQMNDWNERQKADKERAEQAQKEADRLYDLKRREMDER 570
++ + E K + Q + +W ERQK + E +++E DRL L+R+ ER
Sbjct: 125 -KEKEREHERRKRHREEQDKARREW-ERQKRREMAREHSRRERDRLEQLERKRERER 179
>sp|P21127|CD2L1_HUMAN PITSLRE serine/threonine-protein kinase CDC2L1
(Galactosyltransferase-associated protein kinase
p58/GTA) (Cell division cycle 2-like protein kinase 1)
(CLK-1) (CDK11) (p58 CLK-1)
Length = 795
Score = 37.7 bits (86), Expect = 0.047
Identities = 63/295 (21%), Positives = 120/295 (40%), Gaps = 17/295 (5%)
Frame = +1
Query: 73 IFNSKTRQIGIDKQALDQQVKDKKERECTERNVELAYASD-----SIRNDLIA---TLLS 228
I K R+ +++A +++K+ +R+ ++E D +IRN ++
Sbjct: 16 ILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMED 75
Query: 229 KRQQDD---IRELNKILNEFRAFHQQPETRREWDLYDPDALKKDKPARVCDDDPRCGISS 399
+ ++DD I+ ++ + + H++ E R+E + + + K ARV
Sbjct: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARV----------- 124
Query: 400 MQKFDGEDLNNKARTKYQKEQMNDWNERQKADKERAEQAQKEADRLYDLKRREMDERACD 579
++ + E K + Q + +W ERQK + E +++E DRL L+R+ ER
Sbjct: 125 -KEKEREHERRKRHREEQDKARREW-ERQKRREMAREHSRRERDRLEQLERKRERER--- 179
Query: 580 LAAAEEACRRAMNMANSQYNVALFNEMNERA-RLKKQQENDDTLTAMANALYSDLLTENP 756
M Q E RA +K++E ++A + D +
Sbjct: 180 ------------KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 227
Query: 757 AQATSSFGPGRVIPDRFK---GMTPEQLNEIYKQQEDQMKDNK--RRQMEEDLRN 906
A S P R +RF+ G P + Q+ Q+K+ K R + DL++
Sbjct: 228 ASHWSR-SPPRPpreRFELGDGRKPGEARPARAQKPAQLKEEKMEERDLLSDLQD 281
>sp|Q01397|DYNA_NEUCR Dynactin, 150 kDa isoform (150 kDa dynein-associated polypeptide)
(DP-150) (DAP-150) (p150-glued)
Length = 1300
Score = 37.7 bits (86), Expect = 0.047
Identities = 49/203 (24%), Positives = 92/203 (45%), Gaps = 25/203 (12%)
Frame = +1
Query: 379 PRCGISSMQKFDGEDLNNKARTKY-QKEQMNDWN-----ERQKADKERAEQA-------- 516
PR I++ + E + KA+ K +K++M D E+ KA++++ E+
Sbjct: 250 PRSSITNTATMNKEIEDLKAKLKVLEKKRMEDREKLNSLEKVKAERDKFERIIQTLQIKY 309
Query: 517 QKEADRLYDLKR--REMDERACDLAAAEEACRRAMNMANSQYNVALFNEMNERARLKKQQ 690
Q + + DLKR +E + R ++ + AM +A +A + L +
Sbjct: 310 QPQQQEIQDLKRQLKEAENRLYNVEELQAEHDTAMELATLDREMAEETAEVLKVELDALK 369
Query: 691 ENDDTLTAMANALYSDLLTENPAQATSSFGP------GRVIPDRFKGMTPE---QLNEIY 843
+ ++ L L ++L E ++ T+ P G + +R E +L +I
Sbjct: 370 QKNEELE-----LEVEVLREENSEFTNGMSPEERASTGWLQMERNNERLREALIRLRDIT 424
Query: 844 KQQEDQMKDNKRRQMEEDLRNEE 912
+QQE+++KD + + MEEDLR E
Sbjct: 425 QQQEEELKD-QIKSMEEDLREFE 446
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.313 0.128 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,736,667
Number of Sequences: 369166
Number of extensions: 1532223
Number of successful extensions: 5426
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4859
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5297
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9606826000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)