Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_023_B08 (390 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8N3Y1|FBXW8_HUMAN F-box/WD-repeat protein 8 (F-box and ... 32 0.58 sp|O75665|OFD1_HUMAN Oral-facial-digital syndrome 1 protein... 30 2.2 sp|Q9GLG7|CAN3_MACFA Calpain-3 (Calpain L3) (Calpain p94) (... 28 4.9 sp|Q92177|CAN3_CHICK Calpain-3 (Calpain L3) (Calpain p94) (... 28 6.4 sp|P51186|CAN3_BOVIN Calpain-3 (Calpain L3) (Calpain p94) (... 28 8.4 sp|Q28203|TNR5_BOVIN Tumor necrosis factor receptor superfa... 28 8.4
>sp|Q8N3Y1|FBXW8_HUMAN F-box/WD-repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29) Length = 598 Score = 31.6 bits (70), Expect = 0.58 Identities = 13/34 (38%), Positives = 19/34 (55%) Frame = -1 Query: 240 RLFTVENILSGIVCSSVSKRPPTIFVSGNPDSNL 139 RL + N+L C ++S PP + VSGN D + Sbjct: 424 RLLKLGNVLRDFTCVNLSDSPPNLMVSGNMDGRV 457
>sp|O75665|OFD1_HUMAN Oral-facial-digital syndrome 1 protein (Protein 71-7A) Length = 1012 Score = 29.6 bits (65), Expect = 2.2 Identities = 13/38 (34%), Positives = 22/38 (57%) Frame = -1 Query: 252 NFINRLFTVENILSGIVCSSVSKRPPTIFVSGNPDSNL 139 +F+N F EN+L+ +V S ++ P +PDS+L Sbjct: 588 DFLNNPFKQENVLARMVASRITNYPTAWVEGSSPDSDL 625
>sp|Q9GLG7|CAN3_MACFA Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (Cn94) Length = 815 Score = 28.5 bits (62), Expect = 4.9 Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 2/49 (4%) Frame = -1 Query: 282 PISINPYQIENFINRLFTVENILSGIVCSSVS-KRP-PTIFVSGNPDSN 142 P + P+Q FI R+F+ + LS V +++S RP P IFVS +SN Sbjct: 558 PSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVPIIFVSDRANSN 606
>sp|Q92177|CAN3_CHICK Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) Length = 810 Score = 28.1 bits (61), Expect = 6.4 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 8/55 (14%) Frame = -1 Query: 282 PISINPYQIENFINRLFT--------VENILSGIVCSSVSKRPPTIFVSGNPDSN 142 P + P+Q FI R+F+ VEN++ S K P IFVS +SN Sbjct: 551 PSTYEPHQEGEFILRVFSEKRSLSEEVENMIEADRPSKKKKGKPIIFVSDRANSN 605
>sp|P51186|CAN3_BOVIN Calpain-3 (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1) Length = 822 Score = 27.7 bits (60), Expect = 8.4 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 8/55 (14%) Frame = -1 Query: 282 PISINPYQIENFINRLFTVENILSGIVCSSVS--------KRPPTIFVSGNPDSN 142 P + P+Q FI R+F+ + LS V +++S K P IFVS +SN Sbjct: 559 PSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVKKKKNKPIIFVSDRANSN 613
>sp|Q28203|TNR5_BOVIN Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) Length = 269 Score = 27.7 bits (60), Expect = 8.4 Identities = 14/31 (45%), Positives = 16/31 (51%) Frame = +2 Query: 170 IVGGLLDTLEQTIPLNIFSTVKSLLMKFSIW 262 I GLLDT+ + PL FS V S K W Sbjct: 134 IATGLLDTVCEPCPLGFFSNVSSAFEKCHRW 164
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 30,876,744 Number of Sequences: 369166 Number of extensions: 495007 Number of successful extensions: 1165 Number of sequences better than 10.0: 6 Number of HSP's better than 10.0 without gapping: 1156 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1164 length of database: 68,354,980 effective HSP length: 96 effective length of database: 50,620,420 effective search space used: 1670473860 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)