Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_A16
(896 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P12844|MYO3_CAEEL Myosin-3 (Myosin heavy chain A) (MHC A) 55 3e-07
sp|Q62209|SYCP1_MOUSE Synaptonemal complex protein 1 (SCP-1... 55 3e-07
sp|P10587|MYH11_CHICK Myosin-11 (Myosin heavy chain, gizzar... 55 3e-07
sp|P08799|MYS2_DICDI Myosin II heavy chain, non muscle 54 5e-07
sp|P13538|MYSS_CHICK Myosin heavy chain, skeletal muscle, a... 54 8e-07
sp|Q62812|MYH9_RAT Myosin-9 (Myosin heavy chain, nonmuscle ... 52 3e-06
sp|O15078|CE29_HUMAN Centrosomal protein Cep290 51 5e-06
sp|Q96YR5|RAD50_SULTO DNA double-strand break repair rad50 ... 51 5e-06
sp|P35748|MYH11_RABIT Myosin-11 (Myosin heavy chain, smooth... 50 7e-06
sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscl... 50 9e-06
>sp|P12844|MYO3_CAEEL Myosin-3 (Myosin heavy chain A) (MHC A)
Length = 1969
Score = 55.1 bits (131), Expect = 3e-07
Identities = 56/294 (19%), Positives = 128/294 (43%), Gaps = 23/294 (7%)
Frame = +1
Query: 67 QKLENVIRNLEKDKVGLKKEIQERDE-------TIQDKEKRIYDLKKKNQELDKFKFVLD 225
QKLE ++ E + L+ ++ + E +++ ++ + D +++N++L++ K L+
Sbjct: 870 QKLEEAVQRGEIARSQLESQVADLVEEKNALFLSLETEKANLADAEERNEKLNQLKATLE 929
Query: 226 YKIKELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXX 405
K+ ++ Q+E + + Q ++ + EL KH L L++
Sbjct: 930 SKLSDITGQLEDMQERNEDLARQKKKTDQELSDTKKHVQDLELSL--------------- 974
Query: 406 XXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDADIQ 585
R+A ++ +++ ++ +QD +D VA K + S ++ D+Q
Sbjct: 975 --RKAEQEKQSRDHNIRS--------LQDEMANQDEAVAKLNKEKKHQEESNRKLNEDLQ 1024
Query: 586 KE------FTRQREHLERSVASLRKKLSKD----SEIHRADY-----VRIMQENV-SLIK 717
E + R LE+ + L + + ++ +I +A +++ QEN+ + K
Sbjct: 1025 SEEDKVNHLEKIRNKLEQQMDELEENIDREKRSRGDIEKAKRKVEGDLKVAQENIDEITK 1084
Query: 718 EINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELD 879
+ +D+ LK H A L + ++L+ +TA + +E+EL+
Sbjct: 1085 QKHDVETTLKRKEEDLHHTNAKLAENNSIIAKLQRLIKELTARNAE--LEEELE 1136
Score = 31.2 bits (69), Expect = 4.1
Identities = 56/283 (19%), Positives = 119/283 (42%), Gaps = 12/283 (4%)
Frame = +1
Query: 79 NVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKN----QELDKFKFVLDYKIKEL- 243
N + +E K L+ ++QE +T + +I +K Q+LD + ++ ++
Sbjct: 1394 NKLEEIEAAKKALQLKVQELTDTNEGLFAKIASQEKVRFKLMQDLDDAQSDVEKAAAQVA 1453
Query: 244 --KKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQ 417
+K E I K++ ++ SEL+ + N QLS ++ R+
Sbjct: 1454 FYEKHRRQFESIIAEWKKKTDDLSSELDAAQRDNRQLSTDLFKAKTANDELAEYLDSTRR 1513
Query: 418 ATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDADIQKEFT 597
+ + +V+ + D G VA +K +++ +++KE
Sbjct: 1514 ENKSLAQEVKD-----------LTDQLGEGGRSVAELQKIVRK---------LEVEKE-- 1551
Query: 598 RQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNH--- 768
++ L+ + A+L ++++++ RA + + Q + K I + +E +N+R NH
Sbjct: 1552 ELQKALDEAEAALE---AEEAKVLRAQ-IEVSQIRSEIEKRIQEKEEEFENTRR-NHQRA 1606
Query: 769 --DLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELDEAGR 891
++A L KQ E A ++ + ++ +E LD A R
Sbjct: 1607 LESMQATLEAETKQKEEALRIKKKLESDIND--LEIALDHANR 1647
Score = 31.2 bits (69), Expect = 4.1
Identities = 23/92 (25%), Positives = 49/92 (53%), Gaps = 7/92 (7%)
Frame = +1
Query: 70 KLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLK------KKNQE-LDKFKFVLDY 228
+LE IR +E++ G ++ Q+ ++ + E+R+ +++ KKN+E L + L
Sbjct: 1827 QLEARIRAIEQELDGEQRRHQDTEKNWRKAERRVKEVEFQVVEEKKNEERLTELVDKLQC 1886
Query: 229 KIKELKKQIEpreLEIQSAKEQIQEMESELER 324
K+K K+Q+E E S + + + ++ E+
Sbjct: 1887 KLKIFKRQVEEAEEVAASNLNKYKVLTAQFEQ 1918
>sp|Q62209|SYCP1_MOUSE Synaptonemal complex protein 1 (SCP-1 protein)
Length = 993
Score = 54.7 bits (130), Expect = 3e-07
Identities = 63/305 (20%), Positives = 139/305 (45%), Gaps = 31/305 (10%)
Frame = +1
Query: 61 ETQKLENVIRNLEKDKVGLKKEIQE------RDETIQDKEKRIY----DLKKKNQELDKF 210
E QK N + + K K + E++E D+ + D++K++ +L++K QEL
Sbjct: 408 ELQKKSNELEEMTKFKNNKEVELEELKNILAEDQKLLDEKKQVEKLAEELQEKEQELTFL 467
Query: 211 KFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXX 390
+ ++ +L++Q+ + Q +Q++EM++ELE+ N++L+ +
Sbjct: 468 LETREKEVHDLQEQVTVTKTSEQHYLKQVEEMKTELEKEKLKNTELTASCDMLLLENKKF 527
Query: 391 XXXXXXXRQATRDVEAQVRRFKTDLYNC----------VSYIQDPK-GLKDSIVALYKKH 537
Q D+ ++++ + D+ NC + +++ + L+D + ++ K+
Sbjct: 528 V-------QEASDMALELKKHQEDIINCKKQEERLLKQIENLEEKEMHLRDELESVRKEF 580
Query: 538 IQE--------DVTSE--ASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVR 687
IQ+ D + E S++ ++ K+ +Q + LE +L+K++ S+ +
Sbjct: 581 IQQGDEVKCKLDKSEENARSIECEVLKK-EKQMKILESKCNNLKKQVENKSK----NIEE 635
Query: 688 IMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVE 867
+ QEN +L K+ + K+L LE L E+ +Q +T N + +
Sbjct: 636 LHQENKTLKKKSSAEIKQLNAYEIKVSKLELEL-------ESTKQRFEEMTNNYQKEIEN 688
Query: 868 KELDE 882
K++ E
Sbjct: 689 KKISE 693
Score = 47.0 bits (110), Expect = 7e-05
Identities = 48/232 (20%), Positives = 103/232 (44%), Gaps = 7/232 (3%)
Frame = +1
Query: 55 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKI 234
+ E K E ++ LE LKK+++ + + I++ + LKKK+ + K + Y+I
Sbjct: 602 ECEVLKKEKQMKILESKCNNLKKQVENKSKNIEELHQENKTLKKKSSA--EIKQLNAYEI 659
Query: 235 KELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXR 414
K + ELE++S K++ +EM + ++ N ++S
Sbjct: 660 K-----VSKLELELESTKQRFEEMTNNYQK-EIENKKISEGKLLGEVEKAKATVDEAVKL 713
Query: 415 QATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIV-------ALYKKHIQEDVTSEASVD 573
Q D+ Q + + V+ ++ K D IV LYK QE +++ +++
Sbjct: 714 QKEIDLRCQHK-----IAEMVALMEKHKHQYDKIVEERDSELGLYKNREQEQSSAKIALE 768
Query: 574 ADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEIND 729
++ ++ + SL+K+L + E + +++ +EN +++K+ D
Sbjct: 769 TEL--------SNIRNELVSLKKQLEIEKE--EKEKLKMAKENTAILKDKKD 810
>sp|P10587|MYH11_CHICK Myosin-11 (Myosin heavy chain, gizzard smooth muscle)
Length = 1979
Score = 54.7 bits (130), Expect = 3e-07
Identities = 61/247 (24%), Positives = 108/247 (43%), Gaps = 10/247 (4%)
Frame = +1
Query: 70 KLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKK 249
K E++I LE V LKKE + R E + K K L+ ++ +L + L +I ELK
Sbjct: 1037 KHESMISELE---VRLKKEEKSRQELEKIKRK----LEGESSDLHEQIAELQAQIAELKA 1089
Query: 250 QIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRD 429
Q+ +E E+Q+A ++++ S+ K +L +I + RD
Sbjct: 1090 QLAKKEEELQAALARLEDETSQKNNALKKIRELESHISDLQEDLESEKAARNKAEKQKRD 1149
Query: 430 VEAQVRRFKTDLYNCVSYI---QDPKGLKDSIVALYKKHIQEDV-TSEASVDADIQK--- 588
+ ++ KT+L + + Q+ + ++ V + K+ ++E+ T EA V QK
Sbjct: 1150 LSEELEALKTELEDTLDTTATQQELRAKREQEVTVLKRALEEETRTHEAQVQEMRQKHTQ 1209
Query: 589 ---EFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRT 759
E T Q E +R+ A+ L K + D + E SL + D+ + K
Sbjct: 1210 AVEELTEQLEQFKRAKAN----LDKTKQTLEKDNADLANEIRSLSQAKQDVEHKKKKLEV 1265
Query: 760 YNHDLEA 780
DL++
Sbjct: 1266 QLQDLQS 1272
Score = 40.0 bits (92), Expect = 0.009
Identities = 56/296 (18%), Positives = 113/296 (38%), Gaps = 52/296 (17%)
Frame = +1
Query: 94 LEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLE 273
LE+ LK E+++ + D K ++ EL+K K L+ +++E+K Q+E E E
Sbjct: 1508 LERTNKMLKAEMEDLVSSKDDVGKNVH-------ELEKSKRTLEQQVEEMKTQLEELEDE 1560
Query: 274 IQSAKE------------------------------------QIQEMESELERFSKHNSQ 345
+Q+A++ Q+ E E+ELE K +
Sbjct: 1561 LQAAEDAKLRLEVNMQAMKSQFERDLQARDEQNEEKRRQLLKQLHEHETELEDERKQRAL 1620
Query: 346 LSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVAL 525
+ +A + Q+R+ + + + + D + ++ I A
Sbjct: 1621 AAAAKKKLEVDVKDLESQVDSANKAREEAIKQLRKLQAQMKDYQRDLDDARAAREEIFAT 1680
Query: 526 YKKH-------------IQEDVTS--EASVDADIQKEFTRQREHLERSVASLRKKLSKDS 660
+++ +QED+ + A AD++KE + S + + +
Sbjct: 1681 ARENEKKAKNLEAELIQLQEDLAAAERARKQADLEKEEMAEELASANSGRTSLQDEKRRL 1740
Query: 661 EIHRADYVRIMQENVSLIKEIND-LRKELKNSRTYNHDLEAALGLHRKQGEAARQL 825
E A + E S I+ ++D +RK ++ + N++L +K A +QL
Sbjct: 1741 EARIAQLEEELDEEHSNIETMSDRMRKAVQQAEQLNNELATERATAQKNENARQQL 1796
Score = 32.0 bits (71), Expect = 2.4
Identities = 27/123 (21%), Positives = 50/123 (40%), Gaps = 29/123 (23%)
Frame = +1
Query: 67 QKLENVIRNLEKDKVGLKKEIQERDETIQDK---------------EKRIYDLKKKNQEL 201
QK EN + LE+ L+ ++QE + ++ K E+++ ++ Q
Sbjct: 1787 QKNENARQQLERQNKELRSKLQEMEGAVKSKFKSTIAALEAKIASLEEQLEQEAREKQAA 1846
Query: 202 DKFKFVLDYKIKE--------------LKKQIEpreLEIQSAKEQIQEMESELERFSKHN 339
K D K+K+ K Q E L ++ K Q++E E E +R + +
Sbjct: 1847 AKTLRQKDKKLKDALLQVEDERKQAEQYKDQAEKGNLRLKQLKRQLEEAEEESQRINANR 1906
Query: 340 SQL 348
+L
Sbjct: 1907 RKL 1909
>sp|P08799|MYS2_DICDI Myosin II heavy chain, non muscle
Length = 2116
Score = 54.3 bits (129), Expect = 5e-07
Identities = 68/288 (23%), Positives = 124/288 (43%), Gaps = 21/288 (7%)
Frame = +1
Query: 91 NLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIE---- 258
N+EK K L+ ++ + + ++ KK L+K K LD ++E+K Q+E
Sbjct: 1084 NVEKSKKTLESQLVAVNNELDEE-------KKNRDALEKKKKALDAMLEEMKDQLESTGG 1136
Query: 259 ----------preLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXX 408
+E ++++ + QI E++S + + K S L +
Sbjct: 1137 EKKSLYDLKVKQESDMEALRNQISELQSTIAKLEKIKSTLEGEV-------ARLQGELEA 1189
Query: 409 XRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQE--DVTSEASVDADI 582
+ A +VE Q ++ + DL + + + + K ++ L KK QE +V ++ S +
Sbjct: 1190 EQLAKSNVEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKKLEQELSEVQTQLSEANNK 1249
Query: 583 QKEFTRQREHLERSVASLRKKLSKDSEIHRA-DYVRIMQENVSLIKEINDLRKELKNSRT 759
+HLE S +L+ +L + + +A + R+ E S +K +N+ +E K +
Sbjct: 1250 NVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLGLE--SELKHVNEQLEEEKKQKE 1307
Query: 760 YNH----DLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELDEAGR 891
N DLE + + Q E AVT K + E ELDE R
Sbjct: 1308 SNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKK--ESELDEIKR 1353
Score = 45.1 bits (105), Expect = 3e-04
Identities = 54/291 (18%), Positives = 125/291 (42%), Gaps = 16/291 (5%)
Frame = +1
Query: 58 TETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIK 237
T+ KLE +++ E + + L+++++ ET+ K +YD K L+ K L+ +++
Sbjct: 849 TQKDKLEKSLKDTESNVLDLQRQLKAEKETL----KAMYDSK---DALEAQKRELEIRVE 901
Query: 238 ELKKQIEpreLEIQ-------SAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXX 396
+++ +++ ++L ++ S +E+++++E EL+ K L +
Sbjct: 902 DMESELDEKKLALENLQNQKRSVEEKVRDLEEELQEEQK----LRNTLEKLKKKYEEELE 957
Query: 397 XXXXXRQATRDVEAQVRRFKTDLYNCVSYIQD-------PKGLKDSIVALYKKHIQEDVT 555
D +++ + K +L V + + KG+ + + + +D+T
Sbjct: 958 EMKRVNDGQSDTISRLEKIKDELQKEVEELTESFSEESKDKGVLEKTRVRLQSEL-DDLT 1016
Query: 556 SEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQE--NVSLIKEIND 729
+ + E RQ++ LE + +++ L+ ++ ++ QE N L E +
Sbjct: 1017 VRLDSETKDKSELLRQKKKLEEELKQVQEALAAETA------AKLAQEAANKKLQGEYTE 1070
Query: 730 LRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELDE 882
L ++ +N ++ A + + + QLVA V ELDE
Sbjct: 1071 LNEK------FNSEVTARSNVEKSKKTLESQLVA----------VNNELDE 1105
Score = 44.3 bits (103), Expect = 5e-04
Identities = 44/220 (20%), Positives = 95/220 (43%)
Frame = +1
Query: 94 LEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLE 273
LEK ++GL+ E++ +E ++++ KK+ + +K K L+ ++ ELK QIE
Sbjct: 1281 LEKKRLGLESELKHVNEQLEEE-------KKQKESNEKRKVDLEKEVSELKDQIEEEVAS 1333
Query: 274 IQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRF 453
++ E + ESEL+ + + + + R + E Q+ R
Sbjct: 1334 KKAVTEAKNKKESELDEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQLDRA 1393
Query: 454 KTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDADIQKEFTRQREHLERSVAS 633
+ S + L++++ K+++E+ + + ++K T R S
Sbjct: 1394 ER------SKKKAEFDLEEAV-----KNLEEETAKKVKAEKAMKKAETDYR--------S 1434
Query: 634 LRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNS 753
+ +L + YV+I + N +E+++LR L+ +
Sbjct: 1435 TKSELDDAKNVSSEQYVQIKRLN----EELSELRSVLEEA 1470
Score = 43.9 bits (102), Expect = 6e-04
Identities = 58/276 (21%), Positives = 120/276 (43%), Gaps = 3/276 (1%)
Frame = +1
Query: 52 FQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKK-NQELDKFKFVLDY 228
F+ E ++ E I L+ + + + +++++D E + DL+++ E + K + D
Sbjct: 826 FEKEIKEKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLKAMYDS 885
Query: 229 KIKELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXX 408
K + + RELEI+ +++MESEL+ +L+L
Sbjct: 886 KDA---LEAQKRELEIR-----VEDMESELD-----EKKLALE----------------N 916
Query: 409 XRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQ--EDVTSEASVDADI 582
+ R VE +VR + +L Q+ + L++++ L KK+ + E++ +D
Sbjct: 917 LQNQKRSVEEKVRDLEEEL-------QEEQKLRNTLEKLKKKYEEELEEMKRVNDGQSDT 969
Query: 583 QKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTY 762
+ ++ L++ V L + S++S+ D + + V L E++DL L +
Sbjct: 970 ISRLEKIKDELQKEVEELTESFSEESK----DKGVLEKTRVRLQSELDDLTVRLDSE--- 1022
Query: 763 NHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEK 870
D L +K E +Q+ A+ A L ++
Sbjct: 1023 TKDKSELLRQKKKLEEELKQVQEALAAETAAKLAQE 1058
Score = 41.6 bits (96), Expect = 0.003
Identities = 58/294 (19%), Positives = 133/294 (45%), Gaps = 22/294 (7%)
Frame = +1
Query: 70 KLENVIRNLEKDKVGLKKEIQERDET---IQDKEKR----IYDLKKK-------NQELDK 207
KL R LE + ++ +++E +++ ++D ++R + D+KKK N +LD+
Sbjct: 1696 KLVKAKRALEVELEEVRDQLEEEEDSRSELEDSKRRLTTEVEDIKKKYDAEVEQNTKLDE 1755
Query: 208 FKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELERF-SKHNSQLSLNIXXXXXXXX 384
K L + LKKQ+E + ++ ++ + +ESE E F +K ++++
Sbjct: 1756 AKKKLTDDVDTLKKQLEDEKKKLNESERAKKRLESENEDFLAKLDAEV------------ 1803
Query: 385 XXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLK--DSIVALYKKHIQEDVTS 558
+ +R E ++++ DL + + D K I A + +++ S
Sbjct: 1804 ---------KNRSR-AEKDRKKYEKDLKDTKYKLNDEAATKTQTEIGAAKLEDQIDELRS 1853
Query: 559 EASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRK 738
+ + + + ++ LE + +LR ++ + +I +R+ +E +L E+ +LR+
Sbjct: 1854 KLEQEQAKATQADKSKKTLEGEIDNLRAQIEDEGKIK----MRLEKEKRALEGELEELRE 1909
Query: 739 ELKNSRTYNHDLEAALGLHRKQGEAAR-----QLVAAVTANKPQPLVEKELDEA 885
++ + + E + L + E AR ++ A A + +++E+ EA
Sbjct: 1910 TVEEAEDSKSEAEQSKRLVELELEDARRNLQKEIDAKEIAEDAKSNLQREIVEA 1963
Score = 38.1 bits (87), Expect = 0.034
Identities = 46/240 (19%), Positives = 103/240 (42%), Gaps = 9/240 (3%)
Frame = +1
Query: 61 ETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKE 240
E +L+ + + K ++K+ ++ + ++DK ++ + Q LDK K L+ ++ E
Sbjct: 1179 EVARLQGELEAEQLAKSNVEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKKLEQELSE 1238
Query: 241 LKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQA 420
++ Q+ + ++ + +E+ S +N +L L ++A
Sbjct: 1239 VQTQLSEANNKNVNSDSTNKHLET-----SFNNLKLELE----------------AEQKA 1277
Query: 421 TRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDADIQKEFTR 600
+ +E + +++L + +++ K K+ S D++KE +
Sbjct: 1278 KQALEKKRLGLESELKHVNEQLEEEKKQKE---------------SNEKRKVDLEKEVSE 1322
Query: 601 QREHLERSVASLR-------KKLSKDSEIHR--ADYVRIMQENVSLIKEINDLRKELKNS 753
++ +E VAS + KK S+ EI R AD V ++V +K + +EL+N+
Sbjct: 1323 LKDQIEEEVASKKAVTEAKNKKESELDEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNT 1382
>sp|P13538|MYSS_CHICK Myosin heavy chain, skeletal muscle, adult
Length = 1939
Score = 53.5 bits (127), Expect = 8e-07
Identities = 64/269 (23%), Positives = 108/269 (40%), Gaps = 17/269 (6%)
Frame = +1
Query: 88 RNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpre 267
R LE + LKK+I + + T+ EK + + K + L + VLD I +L K+ + +
Sbjct: 944 RKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAVLDETIAKLTKEKKALQ 1003
Query: 268 LEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVR 447
Q + +Q E ++ +K ++L + ++ D+E R
Sbjct: 1004 EAHQQTLDDLQVEEDKVNTLTKAKTKLEQQV-------DDLEGSLEQEKKLRMDLERAKR 1056
Query: 448 RFKTDLYNCVSYIQDPKGLKDSIVALYKK------HIQEDVTSEASVDADIQ---KEFTR 600
+ + DL I D + K + KK IQ + E ++ +Q KE
Sbjct: 1057 KLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQA 1116
Query: 601 QREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKE--------INDLRKELKNSR 756
+ E LE + + R +K +E HRAD R ++E ++E I +K +
Sbjct: 1117 RIEELEEEIEAERTSRAK-AEKHRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQ 1175
Query: 757 TYNHDLEAALGLHRKQGEAARQLVAAVTA 843
DLE A H A R+ A TA
Sbjct: 1176 KMRRDLEEATLQHEATAAALRKKHADSTA 1204
Score = 41.2 bits (95), Expect = 0.004
Identities = 56/269 (20%), Positives = 110/269 (40%), Gaps = 14/269 (5%)
Frame = +1
Query: 85 IRNLEKDKVGLKKEIQERDETIQDKEKRIYD-------LKKKNQELDKFKFVLDYKIKEL 243
I +LE DK L ++++++D I + +I D L+KK IKEL
Sbjct: 1069 IMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKK--------------IKEL 1114
Query: 244 KKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQAT 423
+ +IE E EI++ + + E KH + LS + +
Sbjct: 1115 QARIEELEEEIEAERTSRAKAE-------KHRADLSRELEEISERLEEAGGATAAQIEMN 1167
Query: 424 RDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDAD----IQKE 591
+ EA+ ++ + DL +Q + + AL KKH D T+E D ++++
Sbjct: 1168 KKREAEFQKMRRDLEEAT--LQH----EATAAALRKKH--ADSTAELGEQIDNLQRVKQK 1219
Query: 592 FTRQREHLERSVASLRKKLSKDS--EIHRADYVRIMQENVSLIKEINDLRKELKNS-RTY 762
+++ L+ + L + S + + R +++ +S IK + + + N T
Sbjct: 1220 LEKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQ 1279
Query: 763 NHDLEAALGLHRKQGEAARQLVAAVTANK 849
L+ G + +Q E L++ ++ K
Sbjct: 1280 RARLQTETGEYSRQAEEKDALISQLSRGK 1308
Score = 31.6 bits (70), Expect = 3.1
Identities = 25/100 (25%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Frame = +1
Query: 61 ETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKE 240
+ QKLE +R LE + +K E + ++ E+R+ +L + +E K I
Sbjct: 1814 QLQKLEARVRELEGEVDSEQKRSAEAVKGVRKYERRVKELTYQCEEDRK-------NILR 1866
Query: 241 LKKQIEpreLEIQSAKEQIQEMES----ELERFSKHNSQL 348
L+ ++ +++++S K Q +E E L +F K +L
Sbjct: 1867 LQDLVDKLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHEL 1906
>sp|Q62812|MYH9_RAT Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1961
Score = 51.6 bits (122), Expect = 3e-06
Identities = 60/296 (20%), Positives = 123/296 (41%), Gaps = 26/296 (8%)
Frame = +1
Query: 70 KLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKK 249
++E + L +K+ L++++Q + E + E+ L K QEL++ L+ +++E ++
Sbjct: 870 EMETMQSQLMAEKLQLQEQLQAKTELCAEAEELRARLTAKKQELEEICHDLEARVEEEEE 929
Query: 250 QIEpreLEIQSAKEQIQEMESELERFSKHNSQLSL-------NIXXXXXXXXXXXXXXXX 408
+ + + E + ++ IQE+E +LE +L L +
Sbjct: 930 RCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCK 989
Query: 409 XRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKH------IQEDVTSEASV 570
+ + +E +V F TDL + + S+ L KH ++E + E
Sbjct: 990 LAKEKKLLEDRVAEFTTDL-------MEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQ 1042
Query: 571 DADIQK----------EFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVS---L 711
+++K + + Q L+ +A L+ +L+K E +A R+ +E
Sbjct: 1043 RQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMA 1102
Query: 712 IKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELD 879
+K+I +L ++ DLE+ K + R L + A K + +E LD
Sbjct: 1103 LKKIRELETQISE---LQEDLESERACRNKAEKQKRDLGEELEALKTE--LEDTLD 1153
Score = 39.3 bits (90), Expect = 0.015
Identities = 51/285 (17%), Positives = 111/285 (38%), Gaps = 42/285 (14%)
Frame = +1
Query: 55 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKI 234
+T+ L + + K L++ ++ ++D D+ K EL+K L+ ++
Sbjct: 1476 ETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSNRALEQQV 1535
Query: 235 KELKKQIEpreLEIQSAKE------------------------------------QIQEM 306
+E+K Q+E E E+Q+ ++ Q++EM
Sbjct: 1536 EEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREM 1595
Query: 307 ESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYI 486
E+ELE K S + + Q+R+ + + +C+ +
Sbjct: 1596 EAELEDERKQRSIAMAARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRDV 1655
Query: 487 QDPKGLKDSIVALYKKHIQEDVTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEI 666
D + ++ I+A K++ ++ + EA + +Q+E E +R R +L+ +
Sbjct: 1656 DDTRASREEILAQAKENEKKLKSMEAEM-IQLQEELA-AAERAKRQAQQERDELADEIAN 1713
Query: 667 HRADYVRIMQEN------VSLIKEINDLRKELKNSRTYNHDLEAA 783
++E ++L++E +L +E N+ N L+ A
Sbjct: 1714 SSGKGALALEEKRRLEALIALLEE--ELEEEQGNTELINDRLKKA 1756
Score = 38.9 bits (89), Expect = 0.020
Identities = 19/89 (21%), Positives = 47/89 (52%)
Frame = +1
Query: 55 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKI 234
+ + +LE + N K++ K+++ ++ ++D ++ D ++ ++ ++
Sbjct: 1814 EAKIAQLEEQLDNETKERQAASKQVRRAEKKLKDVLLQVEDERRNAEQFKDQADKASTRL 1873
Query: 235 KELKKQIEpreLEIQSAKEQIQEMESELE 321
K+LK+Q+E E E Q A ++++ ELE
Sbjct: 1874 KQLKRQLEEAEEEAQRANASRRKLQRELE 1902
Score = 33.5 bits (75), Expect = 0.83
Identities = 22/108 (20%), Positives = 48/108 (44%), Gaps = 15/108 (13%)
Frame = +1
Query: 55 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDK---------------EKRIYDLKKK 189
++ QK EN + LE+ LK ++QE + ++ K E+++ + K+
Sbjct: 1771 RSHAQKNENARQQLERQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKE 1830
Query: 190 NQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELERFSK 333
Q K + K+K++ Q+E + K+Q + + L++ +
Sbjct: 1831 RQAASKQVRRAEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKR 1878
>sp|O15078|CE29_HUMAN Centrosomal protein Cep290
Length = 1539
Score = 50.8 bits (120), Expect = 5e-06
Identities = 59/272 (21%), Positives = 115/272 (42%), Gaps = 19/272 (6%)
Frame = +1
Query: 115 LKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKE---LKKQI-EpreLEIQS 282
+++ + E+D+++ + LKK +Q+L++ + + + K+KE +K Q+ E E E++
Sbjct: 686 MEQTVAEQDDSLSSL---LVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKK 742
Query: 283 AKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTD 462
K ++++++ L++ K + L + QA + EA R T
Sbjct: 743 VKAEVEDLKYLLDQSQKESQCLKSEL------------------QAQK--EANSRAPTTT 782
Query: 463 LYNCVSYIQDPKGLKDSIVALYKKHIQE--------------DVTSEASVDADIQKEFTR 600
+ N V ++ LK+ + + E TS+ ++Q+ R
Sbjct: 783 MRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDR 842
Query: 601 QREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKEL-KNSRTYNHDLE 777
L+ V L + L K E + R EN SL +NDL EL K + YN L
Sbjct: 843 HTRELKTQVEDLNENLLKLKEALKTSKNR---EN-SLTDNLNDLNNELQKKQKAYNKILR 898
Query: 778 AALGLHRKQGEAARQLVAAVTANKPQPLVEKE 873
+ ++ E RQ+ + + +PL + +
Sbjct: 899 EKEEIDQENDELKRQIKRLTSGLQGKPLTDNK 930
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/239 (20%), Positives = 99/239 (41%), Gaps = 13/239 (5%)
Frame = +1
Query: 67 QKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVL---DYKIK 237
+KL NLE + +++E + +Q E R L+ + + K V + K+K
Sbjct: 1281 EKLRIAKNNLEILNEKMTVQLEETGKRLQFAESRGPQLEGADSKSWKSIVVTRMYETKLK 1340
Query: 238 ELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXR- 414
EL+ I + I K+ ++E ++ +K+N L I R
Sbjct: 1341 ELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEGAETEQGLKRE 1400
Query: 415 -QATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDADIQ-K 588
Q R Q+ + K +L + + +D G + +I D E D + Q K
Sbjct: 1401 LQVLRLANHQLDKEKAELIHQIEANKDQSGAESTIP-------DADQLKEKIKDLETQLK 1453
Query: 589 EFTRQREHLERSVASLRKKLS-------KDSEIHRADYVRIMQENVSLIKEINDLRKEL 744
+++HL+ + L+K+L ++ E + +Y +++N+ L +++ L ++L
Sbjct: 1454 MSDLEKQHLKEEIKKLKKELENFDPSFFEEIEDLKYNYKEEVKKNILLEEKVKKLSEQL 1512
Score = 33.1 bits (74), Expect = 1.1
Identities = 46/229 (20%), Positives = 89/229 (38%), Gaps = 19/229 (8%)
Frame = +1
Query: 241 LKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLN----------IXXXXXXXXXX 390
LK+Q+E E++ KE++ +E E+ +K ++ S++ I
Sbjct: 63 LKEQVESINKELEITKEKLHTIEQAWEQETKLGNESSMDKAKKSITNSDIVSISKKITML 122
Query: 391 XXXXXXXRQATRDVEAQVRRFKTDLYNCV--SYIQDPKGLKDSIVALYKKHIQE------ 546
RQ + +T L ++ + K + + + L + +++
Sbjct: 123 EMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDEL 182
Query: 547 -DVTSEASVDADIQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEI 723
D S+A DAD Q+ ++ +E V KL + S+I R + + S KE+
Sbjct: 183 ADSVSKAVSDADRQRILELEKNEMELKVEV--SKLREISDIARRQVEILNAQQQSRDKEV 240
Query: 724 NDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEK 870
LR +L + + + + LH Q + QL A K + + K
Sbjct: 241 ESLRMQLLDYQAQSDEKSLIAKLH--QHNVSLQLSEATALGKLESITSK 287
Score = 32.0 bits (71), Expect = 2.4
Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Frame = +1
Query: 73 LENVIRNLEKDKVGLKKEIQERDETIQDKE----KRIYDLKKKNQELDKFKFVLDYKIKE 240
LE ++ + +K LK+EI++ + +++ + + I DLK +E K +L+ K+K+
Sbjct: 1448 LETQLKMSDLEKQHLKEEIKKLKKELENFDPSFFEEIEDLKYNYKEEVKKNILLEEKVKK 1507
Query: 241 LKKQIEpreLEIQSAKEQIQEMESELE 321
L +Q+ +E+ S +E E E E
Sbjct: 1508 LSEQL---GVELTSPVAASEEFEDEEE 1531
Score = 31.2 bits (69), Expect = 4.1
Identities = 17/90 (18%), Positives = 46/90 (51%), Gaps = 6/90 (6%)
Frame = +1
Query: 70 KLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKK 249
KL+ ++ + + L + + + +Q K+K + ++ +E+D+ L +IK L
Sbjct: 860 KLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTS 919
Query: 250 QIEpreLE------IQSAKEQIQEMESELE 321
++ + L I+ + +++++E++LE
Sbjct: 920 GLQGKPLTDNKQSLIEELQRKVKKLENQLE 949
>sp|Q96YR5|RAD50_SULTO DNA double-strand break repair rad50 ATPase
Length = 879
Score = 50.8 bits (120), Expect = 5e-06
Identities = 59/276 (21%), Positives = 118/276 (42%), Gaps = 41/276 (14%)
Frame = +1
Query: 61 ETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEK------RIYDLKKKNQELDKFKFVL 222
E K EN +R EK+K L+K+I E+D+ I++KEK +I ++K + L K L
Sbjct: 264 EEVKDENRLRE-EKEK--LEKDILEKDKLIEEKEKIIEAQNKIKLAQEKEKSLKTIKINL 320
Query: 223 DYKIKELKKQIEpre-----LEIQSAKEQIQEMESELERFSKH----------------N 339
++LK++ E E +EI+ E+++E E + S N
Sbjct: 321 TDLEEKLKRKRELEEDYKKYIEIKGELEELEEKERKFNSLSDRLKSLKIKLSEIESKISN 380
Query: 340 SQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIV 519
++S+NI Q + +Q+ K + + + +K ++
Sbjct: 381 RKISINIEELDKELQKLNEDLNNKNQEREKLASQLGEIKGRIEELNKLLGNLNQVKGNVC 440
Query: 520 AL--------YKKHIQEDVTSEASVDADIQKEFTRQREHLERSVASLRK---KLSKDSEI 666
+ +K+ IQ ++ + ++ K+F + + ++ L + K SK+ +I
Sbjct: 441 PVCGRELSDDHKRKIQNEIIEKLKELDELNKKFKLEINKINGLISELNQIINKKSKEKDI 500
Query: 667 ---HRADYVRIMQENVSLIKEINDLRKELKNSRTYN 765
+ ADY ++ + L KEI ++ E++ Y+
Sbjct: 501 AIRNLADYNNLLTQQQELRKEIEEIENEIERLSIYH 536
Score = 38.9 bits (89), Expect = 0.020
Identities = 52/245 (21%), Positives = 101/245 (41%), Gaps = 7/245 (2%)
Frame = +1
Query: 58 TETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYK-- 231
T +QK++ ++ NL+++ LK I I+ + + D+ KK ++DK + + D
Sbjct: 115 TVSQKIKELL-NLDEEV--LKSTIIVGQGKIESVFENLPDVTKKILKIDKIEKLRDSNGP 171
Query: 232 IKELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXX 411
IKE+ +I + +E+QS ++ E E++ + K + +
Sbjct: 172 IKEVMDKINNKIIELQSLEKYKNESENQKIQKEKELENIKRELEDLNIKEEKERKKYEDI 231
Query: 412 RQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDADIQKE 591
+ + E + +R+ V I LKD I ++E+V E
Sbjct: 232 VKLNEEEEKKEKRY-------VELISLLNKLKDDI-----SELREEVKDE--------NR 271
Query: 592 FTRQREHLERSVASLRKKL-SKDSEIHRADYVRIMQENVSLIKEI----NDLRKELKNSR 756
++E LE+ + K + K+ I + +++ QE +K I DL ++LK R
Sbjct: 272 LREEKEKLEKDILEKDKLIEEKEKIIEAQNKIKLAQEKEKSLKTIKINLTDLEEKLKRKR 331
Query: 757 TYNHD 771
D
Sbjct: 332 ELEED 336
Score = 37.7 bits (86), Expect = 0.044
Identities = 61/284 (21%), Positives = 121/284 (42%), Gaps = 8/284 (2%)
Frame = +1
Query: 55 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKI 234
++E QK++ EK+ +K+E+++ + + + K+ D+ K N+E +K
Sbjct: 195 ESENQKIQK-----EKELENIKRELEDLNIKEEKERKKYEDIVKLNEEEEK--------- 240
Query: 235 KELKKQIEpreLEIQSAKEQIQEMESELE---RFSKHNSQLSLNIXXXXXXXXXXXXXXX 405
KE K+ +E L + K+ I E+ E++ R + +L +I
Sbjct: 241 KE-KRYVELISL-LNKLKDDISELREEVKDENRLREEKEKLEKDILEKDKLIEEKEKIIE 298
Query: 406 XXR--QATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDAD 579
+ ++ E ++ K +L + ++ + L++ YKK+I E + +
Sbjct: 299 AQNKIKLAQEKEKSLKTIKINLTDLEEKLKRKRELEED----YKKYI------EIKGELE 348
Query: 580 IQKEFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENV-SLIKEINDLRKELKNSR 756
+E R+ L + SL+ KL SEI R + N+ L KE+ L ++L N
Sbjct: 349 ELEEKERKFNSLSDRLKSLKIKL---SEIESKISNRKISINIEELDKELQKLNEDLNNKN 405
Query: 757 TYNHDLEAALGLHRKQGEAARQLVAAVTANKPQ--PLVEKELDE 882
L + LG + + E +L+ + K P+ +EL +
Sbjct: 406 QEREKLASQLGEIKGRIEELNKLLGNLNQVKGNVCPVCGRELSD 449
Score = 31.6 bits (70), Expect = 3.1
Identities = 54/267 (20%), Positives = 106/267 (39%), Gaps = 4/267 (1%)
Frame = +1
Query: 91 NLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreL 270
NL + L+KEI+E I+++ +R+ +K L + + L K +E K + E
Sbjct: 510 NLLTQQQELRKEIEE----IENEIERLSIYHEKYIRLKEEEKNLKPKYEEYLKYYDVTEE 565
Query: 271 EIQSAKEQIQEMESELER-FSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVR 447
+I+ + Q E+E E+E +K + ++ R+++ +
Sbjct: 566 KIRELERQKIELEKEIEEIMNKVREYYNTDLTQKIRDIEKRIQEIKGKENKLRELDTLLA 625
Query: 448 RFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDADIQKEFTRQREHLERSV 627
+ +T ++ K L D + L + D + ++ R++E LE+ +
Sbjct: 626 KIETAKQKIKQNEEEIKKLTDELQLL-------------NFDPNRFQQIKREKEVLEKIL 672
Query: 628 ASLRKK---LSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHR 798
+ K L E+ D R L ++I D ++LKN + + A L +
Sbjct: 673 GEINSKKGELLGKKEVLENDIKR-------LEEQIKDYEEKLKNKQKL---ITAYDKLKK 722
Query: 799 KQGEAARQLVAAVTANKPQPLVEKELD 879
+ A + A N + LVE L+
Sbjct: 723 LREHLAEDKLQAYLMNTVKSLVEDSLN 749
>sp|P35748|MYH11_RABIT Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length = 1972
Score = 50.4 bits (119), Expect = 7e-06
Identities = 59/247 (23%), Positives = 104/247 (42%), Gaps = 24/247 (9%)
Frame = +1
Query: 79 NVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLD----------- 225
N+ EK K L K + + I + E R+ +K QEL+K K +D
Sbjct: 1014 NLAEEEEKAK-NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKMDGEASDLHEQIA 1072
Query: 226 ---YKIKELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXX 396
+I ELK Q+ +E E+Q+A ++++ S+ K +L +I
Sbjct: 1073 DLQAQIAELKMQLAKKEEELQAALARLEDETSQKNNALKKIRELEGHISDLQEDLDSERA 1132
Query: 397 XXXXXRQATRDVEAQVRRFKTDLYNCVSYI---QDPKGLKDSIVALYKKHIQEDVTS-EA 564
+ RD+ ++ KT+L + + Q+ + ++ V + KK + E+ S EA
Sbjct: 1133 ARNKAEKQKRDLGEELEALKTELEDTLDTTATQQELRAKREQEVTVLKKALDEETRSHEA 1192
Query: 565 SVDADIQK------EFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVSLIKEIN 726
V QK E T Q E +R+ A+L K + E AD ++ +E+
Sbjct: 1193 QVQEMRQKHTQVVEELTEQLEQFKRAKANL-DKTKQTLEKENADLAGELRVLGQAKQEVE 1251
Query: 727 DLRKELK 747
+K+L+
Sbjct: 1252 HKKKKLE 1258
Score = 41.2 bits (95), Expect = 0.004
Identities = 42/209 (20%), Positives = 91/209 (43%), Gaps = 11/209 (5%)
Frame = +1
Query: 229 KIKELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXX 408
++ +++++ +E E+Q KE+ Q+ ESEL+ + ++QLS
Sbjct: 846 QVTRQEEEMQAKEDELQKIKERQQKAESELQELQQKHTQLSEEKNLLQEQLQAETELYAE 905
Query: 409 XRQATRDVEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTSEASVDADIQK 588
+ + A+ + + L+ + +++ + + A KK Q+ + E ++ ++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE---EE 962
Query: 589 EFTRQREHLERSVASLR-KKLSKDSEIHRADYVRIMQENVSLIKEINDL----------R 735
E RQ+ LE+ A + KKL D + ++ +E L + I+DL
Sbjct: 963 EAARQKLQLEKVTAEAKIKKLEDDILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1022
Query: 736 KELKNSRTYNHDLEAALGLHRKQGEAARQ 822
K L + + + + L + K+ E +RQ
Sbjct: 1023 KNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Score = 40.4 bits (93), Expect = 0.007
Identities = 20/102 (19%), Positives = 53/102 (51%)
Frame = +1
Query: 55 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKI 234
+ + +LE + ++K K +++RD+ +++ ++ D +K ++ + + K+
Sbjct: 1820 EAKIAQLEEQVEQEAREKQAAAKALKQRDKKLKEMLLQVEDERKMAEQYKEQAEKGNAKV 1879
Query: 235 KELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNI 360
K+LK+Q+E E E Q ++++ EL+ ++ N + +
Sbjct: 1880 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREV 1921
Score = 36.6 bits (83), Expect = 0.098
Identities = 46/303 (15%), Positives = 124/303 (40%), Gaps = 24/303 (7%)
Frame = +1
Query: 55 QTETQKLENVIRNLEKDKVGLKKEI-------QERDETIQDKEKRIYDLKKKNQELDKFK 213
Q E + + ++ E + L KE+ Q+ E +Q++ ++ ++ K ++L+ +
Sbjct: 1286 QNEVESVTGMLSEAEGKAIKLAKEVASLGSQLQDTQELLQEETRQKLNVSTKLRQLEDER 1345
Query: 214 FVLDYKIKE-------LKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXX 372
L ++ E L++ I +++ +K+++Q+ S +E + + I
Sbjct: 1346 NSLQEQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVESLEEGKKRFQKEIESLT 1405
Query: 373 XXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYN---CVSYIQDPKGLKDSIVALYKKHIQ 543
+ ++ ++ DL N VS ++ + D ++A +
Sbjct: 1406 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQLLA-----EE 1460
Query: 544 EDVTSEASVDADIQKEFTRQREHLERSVA-------SLRKKLSKDSEIHRADYVRIMQEN 702
++++S+ + + D + R++E S+A +++L + +++ +A+ ++
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1520
Query: 703 VSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELDE 882
+ K +++L K + T +++ L + +A + N V+ E D
Sbjct: 1521 DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKVQFERDL 1580
Query: 883 AGR 891
R
Sbjct: 1581 QAR 1583
Score = 35.0 bits (79), Expect = 0.28
Identities = 49/253 (19%), Positives = 106/253 (41%), Gaps = 11/253 (4%)
Frame = +1
Query: 52 FQTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYK 231
F+ L+ + LEK+ L E++ + Q+ E + L+ + QEL +
Sbjct: 1215 FKRAKANLDKTKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEVQLQELQSKCSDGERA 1274
Query: 232 IKELKKQIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXX 411
EL ++ + E++S + E E + + +K + L +
Sbjct: 1275 RAELNDKVHKLQNEVESVTGMLSEAEGKAIKLAKEVASLGSQL----------------- 1317
Query: 412 RQATRDVEAQVRRFKTDLYNCVSYIQDPKG-----LKDSIVALYKKHIQEDVTSEASVDA 576
Q T+++ + R K ++ + ++D + L + + A K++++ +++ +
Sbjct: 1318 -QDTQELLQEETRQKLNVSTKLRQLEDERNSLQEQLDEEMEA--KQNLERHISTLNIQLS 1374
Query: 577 DIQK---EFTRQREHLERSVASLRKK---LSKDSEIHRADYVRIMQENVSLIKEINDLRK 738
D +K +F E LE +K+ L++ E A Y ++ + L +E++DL
Sbjct: 1375 DSKKKLQDFASTVESLEEGKKRFQKEIESLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 739 ELKNSRTYNHDLE 777
+L N R +LE
Sbjct: 1435 DLDNQRQLVSNLE 1447
Score = 34.7 bits (78), Expect = 0.37
Identities = 50/254 (19%), Positives = 108/254 (42%), Gaps = 3/254 (1%)
Frame = +1
Query: 94 LEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKKQIEpreLE 273
LE+ LK E+++ + D K ++ EL+K K L+ +++E+K Q+E E E
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVH-------ELEKSKRALETQMEEMKTQLEELEDE 1554
Query: 274 IQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRF 453
+Q+ ++ +E ++ + + R ++ Q+ +
Sbjct: 1555 LQATEDAKLRLEVNMQALKVQFER-------------DLQARDEQNEEKRRQLQRQLHEY 1601
Query: 454 KTDLYNCVSYIQDPKGLKDSIVALYKKHIQEDVTS-EASVDADI--QKEFTRQREHLERS 624
+T+L + + + ++ A KK ++ D+ E D+ I ++E +Q L+
Sbjct: 1602 ETEL--------EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLLKLQAQ 1653
Query: 625 VASLRKKLSKDSEIHRADYVRIMQENVSLIKEINDLRKELKNSRTYNHDLEAALGLHRKQ 804
+ +++L +D+ R + +EN K + +L+ DL AA RKQ
Sbjct: 1654 MKDFQREL-EDARASRDEIFATAKENEKKAKSLEADLMQLQ------EDL-AAAERARKQ 1705
Query: 805 GEAARQLVAAVTAN 846
+ ++ +A A+
Sbjct: 1706 ADLEKEELAEELAS 1719
Score = 33.9 bits (76), Expect = 0.63
Identities = 27/127 (21%), Positives = 54/127 (42%), Gaps = 29/127 (22%)
Frame = +1
Query: 55 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDK---------------EKRIYDLKKK 189
++ QK E+ + LE+ LK ++QE + ++ K E+++ ++
Sbjct: 1777 RSTAQKNESARQQLERQNKELKSKLQEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836
Query: 190 NQELDKFKFVLDYKIKEL--------------KKQIEpreLEIQSAKEQIQEMESELERF 327
Q K D K+KE+ K+Q E +++ K Q++E E E +R
Sbjct: 1837 KQAAAKALKQRDKKLKEMLLQVEDERKMAEQYKEQAEKGNAKVKQLKRQLEEAEEESQRI 1896
Query: 328 SKHNSQL 348
+ + +L
Sbjct: 1897 NANRRKL 1903
>sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1960
Score = 50.1 bits (118), Expect = 9e-06
Identities = 54/289 (18%), Positives = 118/289 (40%), Gaps = 19/289 (6%)
Frame = +1
Query: 70 KLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKIKELKK 249
++E + L +K+ L++++Q E + E+ L K QEL++ L+ +++E ++
Sbjct: 870 EMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEE 929
Query: 250 QIEpreLEIQSAKEQIQEMESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRD 429
+ + + E + ++ IQE+E +LE +L L
Sbjct: 930 RCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCK 989
Query: 430 VEAQVRRFKTDLYNCVSYIQDPKGLKDSIVALYKKH------IQEDVTSEASVDADIQK- 588
+ + + + + + + + + S+ L KH ++E + E +++K
Sbjct: 990 LAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKT 1049
Query: 589 ---------EFTRQREHLERSVASLRKKLSKDSEIHRADYVRIMQENVS---LIKEINDL 732
+ + Q L+ +A L+ +L+K E +A R+ +E +K+I +L
Sbjct: 1050 RRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIREL 1109
Query: 733 RKELKNSRTYNHDLEAALGLHRKQGEAARQLVAAVTANKPQPLVEKELD 879
++ DLE+ K + R L + A K + +E LD
Sbjct: 1110 ESQISE---LQEDLESERASRNKAEKQKRDLGEELEALKTE--LEDTLD 1153
Score = 43.5 bits (101), Expect = 8e-04
Identities = 63/309 (20%), Positives = 119/309 (38%), Gaps = 53/309 (17%)
Frame = +1
Query: 55 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKI 234
+T+ L + + K L++ ++ ++D D+ K EL+K K L+ ++
Sbjct: 1475 ETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQV 1534
Query: 235 KELKKQIEpreLEIQSAKE------------------------------------QIQEM 306
+E+K Q+E E E+Q+ ++ Q++EM
Sbjct: 1535 EEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREM 1594
Query: 307 ESELERFSKHNSQLSLNIXXXXXXXXXXXXXXXXXRQATRDVEAQVRRFKTDLYNCVSYI 486
E+ELE K S + + Q+R+ + + +C+ +
Sbjct: 1595 EAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMREL 1654
Query: 487 QDPKGLKDSIVALYKKHIQEDVTSEASVDADIQKEFT----------RQREHLERSVASL 636
D + ++ I+A K++ ++ + EA + +Q+E ++R+ L +A+
Sbjct: 1655 DDTRASREEILAQAKENEKKLKSMEAEM-IQLQEELAAAERAKRQAQQERDELADEIANS 1713
Query: 637 RKKLSKDSEIHRADYVRIMQENVSLIKE------IND-LRKELKNSRTYNHDLEAALGLH 795
K + E R RI Q L +E IND L+K N DL H
Sbjct: 1714 SGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERS-H 1772
Query: 796 RKQGEAARQ 822
++ E ARQ
Sbjct: 1773 AQKNENARQ 1781
Score = 37.0 bits (84), Expect = 0.075
Identities = 19/89 (21%), Positives = 47/89 (52%)
Frame = +1
Query: 55 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDKEKRIYDLKKKNQELDKFKFVLDYKI 234
+ + +LE + N K++ K+++ ++ ++D ++ D ++ ++ ++
Sbjct: 1813 EAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRL 1872
Query: 235 KELKKQIEpreLEIQSAKEQIQEMESELE 321
K+LK+Q+E E E Q A ++++ ELE
Sbjct: 1873 KQLKRQLEEAEEEAQRANASRRKLQRELE 1901
Score = 32.0 bits (71), Expect = 2.4
Identities = 22/108 (20%), Positives = 49/108 (45%), Gaps = 15/108 (13%)
Frame = +1
Query: 55 QTETQKLENVIRNLEKDKVGLKKEIQERDETIQDK---------------EKRIYDLKKK 189
++ QK EN + LE+ LK ++QE + T++ K E+++ + K+
Sbjct: 1770 RSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKE 1829
Query: 190 NQELDKFKFVLDYKIKELKKQIEpreLEIQSAKEQIQEMESELERFSK 333
Q K + K+K++ Q++ + K+Q + + L++ +
Sbjct: 1830 RQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKR 1877
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.312 0.129 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,604,505
Number of Sequences: 369166
Number of extensions: 1506735
Number of successful extensions: 7349
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5658
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7015
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9030416440
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)