Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_A09
(746 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99613|IF38_HUMAN Eukaryotic translation initiation fact... 147 3e-35
sp|O02328|IF38_CAEEL Probable eukaryotic translation initia... 134 2e-31
sp|O14164|IF38_SCHPO Probable eukaryotic translation initia... 90 6e-18
sp|O49160|IF38_ARATH Eukaryotic translation initiation fact... 72 2e-12
sp|Q9XHM1|IF38_MEDTR Eukaryotic translation initiation fact... 67 5e-11
sp|P32497|IF38_YEAST Eukaryotic translation initiation fact... 66 1e-10
sp|P11716|RYR1_RABIT Ryanodine receptor 1 (Skeletal muscle-... 31 3.1
sp|P75524|PKNS_MYCPN Putative serine/threonine-protein kinase 31 3.1
sp|P53339|YG61_YEAST Hypothetical 16.8 kDa protein in AGT1-... 31 4.0
sp|Q39575|DYHG_CHLRE Dynein gamma chain, flagellar outer arm 30 5.3
>sp|Q99613|IF38_HUMAN Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110)
(eIF3c)
Length = 913
Score = 147 bits (371), Expect = 3e-35
Identities = 94/267 (35%), Positives = 146/267 (54%), Gaps = 20/267 (7%)
Frame = +3
Query: 6 SQVDILQQLIELVISRGFGIGLQVKIMVSLVSLLLQYKCSASNPCMTLENWKKILDCTFN 185
+Q+++LQ L+++ G G+ VKI ++++ L Y + + M E W K LDC
Sbjct: 349 AQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLAT-YMKPEMWGKCLDCINE 407
Query: 186 IMDILNKNLTDISMRISDIDENERLDTA--PYFVSGCIVGFLEHLEDEYTKILTYHDFSS 359
+MDIL N +I + + ++E+E L A P V GCI+ +E +++E+TKI+ D S
Sbjct: 408 LMDILFAN-PNIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHS 466
Query: 360 DKEVEYRDKLHYETKMVSLCSVVSDYLNKKNYGDDEKCRVYMRQLEHIYYRFDPTVDIKE 539
+ VE+ L E ++ ++ V YL +K +E CR+Y+ ++ H YY+FD ++
Sbjct: 467 QEYVEH---LKDEAQVCAIIERVQRYLEEKGT-TEEVCRIYLLRILHTYYKFDYKAHQRQ 522
Query: 540 EIP------------------SYKEMRRLSGYITSRDETDRLRTRAILCHIYYLALHDYW 665
P S M RL YI ++D TDR+RT AILCHIY+ ALH W
Sbjct: 523 LTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRW 582
Query: 666 FEARDMMAMSALTNLIDRADASTQILF 746
++ARD+M MS L + I AD QIL+
Sbjct: 583 YQARDLMLMSHLQDNIQHADPPVQILY 609
>sp|O02328|IF38_CAEEL Probable eukaryotic translation initiation factor 3 subunit 8 (eIF3
p110) (eIF3c)
Length = 898
Score = 134 bits (338), Expect = 2e-31
Identities = 82/247 (33%), Positives = 134/247 (54%), Gaps = 5/247 (2%)
Frame = +3
Query: 21 LQQLIELVISRGFGIGLQVKIMVSLVSLLLQYKCSASNPCMTLENWKKILDCTFNIMDIL 200
L++L+E+ + G+G+ VKI ++S L + S+ M E + L +++D+L
Sbjct: 329 LRKLLEVSEEKELGLGINVKISFCIISALFELNAKISDH-MEYETFMTTLQTVNSLLDLL 387
Query: 201 -NKNLTDISMRISDIDENERLDTAPYFVSGCIVGFLEHLEDEYTKILTYHDFSSDKEVEY 377
+ +S+ ++ DEN + DT Y + G I+ ++ L+ E KIL D S+ +Y
Sbjct: 388 IGTDRVKLSVTYAEEDENLKDDTQEYRIQGSILIAVQRLDGELAKILQNADCHSN---DY 444
Query: 378 RDKLHYETKMVSLCSVVSDYLNKKN----YGDDEKCRVYMRQLEHIYYRFDPTVDIKEEI 545
+KL E M SL Y+ +N + E C+VYM ++EH YY++ + E
Sbjct: 445 IEKLKAEKDMCSLIEKAEKYVELRNDSGIFDKHEVCKVYMMRIEHAYYKYQD----QNEE 500
Query: 546 PSYKEMRRLSGYITSRDETDRLRTRAILCHIYYLALHDYWFEARDMMAMSALTNLIDRAD 725
+ K M L I + D+ RLR RA+LCH+YYLA+HD W ARD++ MS + ++D +D
Sbjct: 501 DAGKLMDYLCNKIYTLDDEKRLRQRAMLCHVYYLAVHDKWHRARDLLLMSHMQAIVDHSD 560
Query: 726 ASTQILF 746
TQIL+
Sbjct: 561 VDTQILY 567
>sp|O14164|IF38_SCHPO Probable eukaryotic translation initiation factor 3 93 kDa subunit
(eIF3 p93)
Length = 918
Score = 90.1 bits (222), Expect = 6e-18
Identities = 73/252 (28%), Positives = 120/252 (47%), Gaps = 28/252 (11%)
Frame = +3
Query: 72 QVKIMVSLVSLLLQYKCSASNPCMTLENWKKILDCTFNIMDILNKNLTDISMRISDIDEN 251
++++ V+L+++ + S M ++ W L +I+DI + N + + + DEN
Sbjct: 371 RLRVKVALLAVRFDIN-TGSGQYMPIDQWNAALTELHSILDIFDANPKIVIVEQVE-DEN 428
Query: 252 ERLDTA---------PYFVSGCIVGFLEHLEDEYTKILTYHDFSSDKEVEYRDKLHYETK 404
E + A V G +V FLE L+DE+T+ L D + EY D+L ET
Sbjct: 429 EEEEEAIAAAENNNGVIQVQGSVVSFLERLDDEFTRSLQMIDPHTP---EYIDRLKDETS 485
Query: 405 MVSLCSVVSDYLNKKNYGDDEKCRVYMRQLEHIYYRFDPTVDIKEEIPSYKEMRRLSGYI 584
+ +L YL + ++ R+ MR+L+ +YY+ + + EE+ I
Sbjct: 486 LYTLLVRSQGYLERIGVVENT-ARLIMRRLDRVYYKPEQVIRANEEVAWRSFPPTFDLTI 544
Query: 585 TSRDETDR-------------------LRTRAILCHIYYLALHDYWFEARDMMAMSALTN 707
T R T LRTRA+LCHIY+ AL + +++ARDM+ MS L +
Sbjct: 545 TPRATTTTPDILIHSLCVYLYNNGVSLLRTRAMLCHIYHEALQNRFYKARDMLLMSHLQD 604
Query: 708 LIDRADASTQIL 743
+ AD +TQIL
Sbjct: 605 SVHAADIATQIL 616
>sp|O49160|IF38_ARATH Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110)
(eIF3c) (p105)
Length = 900
Score = 71.6 bits (174), Expect = 2e-12
Identities = 75/267 (28%), Positives = 115/267 (43%), Gaps = 42/267 (15%)
Frame = +3
Query: 72 QVKIMVSLVSLLLQYKCSASNPCMTLENWKKILDCTFNIMDILNKNLTDISMRISDIDEN 251
+++I+ S++S S M + WKK + I+DIL K + + DEN
Sbjct: 280 KLEILFSVISAQFDVNPGLSGH-MPINVWKKCVLNMLTILDILVKYSNIVVDDTVEPDEN 338
Query: 252 ERLDTAPYF----VSGCIVGFLEHLEDEYTKILTYHDFSSDKEVEYRDKLHYETKMVSLC 419
E Y V G +V FLE ++ E+ K L D + EY ++L E ++L
Sbjct: 339 ETSKPTDYDGKIRVWGNLVAFLERVDTEFFKSLQCIDPHTR---EYVERLRDEPMFLALA 395
Query: 420 SVVSDYLNKKNYGDDEKC-RVYMRQLEHIYYRFDPTVD-------IKEEIPSYKEMRRLS 575
+ DY + GD + +V +R++E IYY+ D + EE +E + S
Sbjct: 396 QNIQDYFERM--GDFKAAAKVALRRVEAIYYKPQEVYDAMRKLAELVEEEEETEEAKEES 453
Query: 576 GYITS------------------------------RDETDRLRTRAILCHIYYLALHDYW 665
G TS R+ +R + RA+LC I + AL D +
Sbjct: 454 GPPTSFIVVPEVVPRKPTFPESSRAMMDILVSLIYRNGDERTKARAMLCDINHHALMDNF 513
Query: 666 FEARDMMAMSALTNLIDRADASTQILF 746
ARD++ MS L + I D STQILF
Sbjct: 514 VTARDLLLMSHLQDNIQHMDISTQILF 540
>sp|Q9XHM1|IF38_MEDTR Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110)
(eIF3c)
Length = 935
Score = 67.0 bits (162), Expect = 5e-11
Identities = 75/275 (27%), Positives = 123/275 (44%), Gaps = 50/275 (18%)
Frame = +3
Query: 72 QVKIMVSLVSLLLQYKCSASNPCMTLENWKKILDCTFNIMDILNKNLTDISMRISD---I 242
+++I+ S+VS S M + WKK C N++ IL+ + ++++ D +
Sbjct: 295 KLQILFSVVSAQFDVNPGLSGH-MPISVWKK---CVQNMLVILDILVQHPNIKVDDSVEL 350
Query: 243 DENERLD----TAPYFVSGCIVGFLEHLEDEYTKILTYHDFSSDKEVEYRDKLHYETKMV 410
DENE P V G +V FLE ++ E+ K L D + EY ++L E + V
Sbjct: 351 DENETKKGDDYNGPINVWGNLVAFLEKIDAEFFKSLQCIDPHTR---EYVERLRDEPQFV 407
Query: 411 SLCSVVSDYLNKKNYGDDE-KCRVYMRQLEHIYYR------------------------- 512
L V +YL ++ GD + +V ++++E IYY+
Sbjct: 408 VLAQNVQEYL--ESIGDFKASSKVALKRVELIYYKPHEVYEATRKLAEMTVEGDNGEMSE 465
Query: 513 -------------FDPTVDIKEEIPSYKE-MRRLSGYITS---RDETDRLRTRAILCHIY 641
F T+++ P++ E R L + S + +R + RA+LC IY
Sbjct: 466 EPKGFEDTRIPAPFVVTLELVARKPTFPENSRTLMDVLVSLIYKYGDERTKARAMLCDIY 525
Query: 642 YLALHDYWFEARDMMAMSALTNLIDRADASTQILF 746
+ AL D + ARD++ MS L + D STQILF
Sbjct: 526 HHALLDEFAVARDLLLMSHLQENVHHMDISTQILF 560
>sp|P32497|IF38_YEAST Eukaryotic translation initiation factor 3 93 kDa subunit (eIF3 p93)
(Nuclear transport protein NIP1)
Length = 812
Score = 65.9 bits (159), Expect = 1e-10
Identities = 59/251 (23%), Positives = 110/251 (43%), Gaps = 29/251 (11%)
Frame = +3
Query: 81 IMVSLVSLLLQYKCSASNPCMTLENWKKILDCTFNIMDILNKNLTDISMR-----ISDID 245
IM L + ++ SA+ ++ WK + ++ IL++ + + I I+
Sbjct: 293 IMAYLTLIPSRFDASANLSYQPIDQWKSSFNDISKLLSILDQTIDTYQVNEFADPIDFIE 352
Query: 246 ENERLDT-APYFVSGCIVGFLEHLEDEYTK-ILTYHDFSSDKEVEYRDKLHYETKMVSLC 419
+ + D+ + G I F+E L+DE+ K +L SSD + RD+ ++
Sbjct: 353 DEPKEDSDGVKRILGSIFSFVERLDDEFMKSLLNIDPHSSDYLIRLRDEQSIYNLILRTQ 412
Query: 420 SVVSDYLNKKNYGDDEKCRVYMRQLEHIYYRFDPTVDIKEEIPSYKEMRRLSGYITSRDE 599
L ++ + R ++++L+HIYY+ + + I E + TS+D+
Sbjct: 413 LYFEATLKDEHDLERALTRPFVKRLDHIYYKSENLIKIMETAAWNIIPAQFKSKFTSKDQ 472
Query: 600 TDR----------------------LRTRAILCHIYYLALHDYWFEARDMMAMSALTNLI 713
D ++ RAIL +IYY AL+ + A+DM+ S + I
Sbjct: 473 LDSADYVDNLIDGLSTILSKQNNIAVQKRAILYNIYYTALNKDFQTAKDMLLTSQVQTNI 532
Query: 714 DRADASTQILF 746
++ D+S QILF
Sbjct: 533 NQFDSSLQILF 543
>sp|P11716|RYR1_RABIT Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1)
(RYR-1) (Skeletal muscle calcium release channel)
Length = 5037
Score = 31.2 bits (69), Expect = 3.1
Identities = 48/215 (22%), Positives = 91/215 (42%), Gaps = 27/215 (12%)
Frame = +3
Query: 6 SQVDILQQLIEL-------VISRGFGIGLQVKIMVSLVSLLLQYKCSASNPCMTLENWKK 164
SQ+++L++L++L ++S G + I +V +L++ S+SN M L K
Sbjct: 4008 SQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVE---SSSNVEMIL----K 4060
Query: 165 ILDCTFNIMDILNKN-----LTDISMRISDIDENERLDTAPYFVSGCIVGFLEHLEDEYT 329
D + DI+ +TD IS D + +D+ F I L E +
Sbjct: 4061 FFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADEN 4120
Query: 330 KILTYHDFSSDKEVEYRD-KLHYETKMVSLCSVVSDYLNKKNYGDD-----EKCRVYM-- 485
+++ + +F++ + RD + + +L V +N+ + E R Y+
Sbjct: 4121 EMINFEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGR 4180
Query: 486 -------RQLEHIYYRFDPTVDIKEEIPSYKEMRR 569
R++E IY+ T + E+P KE +R
Sbjct: 4181 IEIMGASRRIERIYFEISETNRAQWEMPQVKESKR 4215
>sp|P75524|PKNS_MYCPN Putative serine/threonine-protein kinase
Length = 389
Score = 31.2 bits (69), Expect = 3.1
Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 11/106 (10%)
Frame = +3
Query: 153 NWKKILDCTFNIMDILNKNLTD----ISMRISDIDENERLDTAPYFVSGCIVGFLEHLED 320
NWKK LD T + +KNL +S R+S + EN+ + LED
Sbjct: 67 NWKKFLDGTITTTRVSHKNLVQTFDVVSPRLSVLSENQVI----------------VLED 110
Query: 321 EYTKILTYHDFSSDKEV-------EYRDKLHYETKMVSLCSVVSDY 437
++ Y D S +E+ ++ ++Y TK+V + + + +
Sbjct: 111 TVMIVMEYVDGPSLREMLNQKGYFSVQEVVYYFTKLVKVINYLHSF 156
>sp|P53339|YG61_YEAST Hypothetical 16.8 kDa protein in AGT1-MAL1S intergenic region
precursor
Length = 147
Score = 30.8 bits (68), Expect = 4.0
Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 2/126 (1%)
Frame = -2
Query: 430 LTTLHNDTIFVS*CNLSRYSTSLSEEKSWYVKIFVYSSSKCSKKPTMQPLTKYGAVSNLS 251
L + + F+S L +S S SE +W ++ V S SK + P +K +
Sbjct: 24 LASFASSVAFIS---LITFSLSSSESPNW-AELVVNSKWSSSKALSFFPSSKSSVLKTSC 79
Query: 250 FSSISLIRIEMSVRFLFNMSIILNVQSKIFFQFSSVMHGFDALHLYCNSSD--TNETIIF 77
+ +ISL EM + F + L IFF + + F L + +S+ TN I+
Sbjct: 80 WFTISLEDSEMFLSSFFEAAFFLLTNEMIFF---ILYYFFSCLMFFYVASERNTNPKILQ 136
Query: 76 TCKPIP 59
T P
Sbjct: 137 TINTKP 142
>sp|Q39575|DYHG_CHLRE Dynein gamma chain, flagellar outer arm
Length = 4485
Score = 30.4 bits (67), Expect = 5.3
Identities = 27/121 (22%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Frame = +3
Query: 87 VSLVSLLLQYKCSASNPCMTLENWKKILDCTFNIMDILNKNLTDISMRISDIDENERLDT 266
VSL+ + Q+ + + K I++ +D L +++ +I++R+ D+ +N+R +
Sbjct: 1667 VSLLGIQFQWTAETQMALSSAKVDKTIMNKNMKKVDALLRDMVNITVRL-DLTKNQRTN- 1724
Query: 267 APYFVSGCIVGFLEHLEDEYT----KILTYHDFSSDKEVEYRDKLHYETKMVSLCSVVSD 434
+ CI + E KI DF K+V + + +T ++S+C V +
Sbjct: 1725 ----LETCITVHMHQKESTEDLVKKKIKDPTDFEWLKQVRFYWRDDKDTVIISICDVDFE 1780
Query: 435 Y 437
Y
Sbjct: 1781 Y 1781
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,304,736
Number of Sequences: 369166
Number of extensions: 1659040
Number of successful extensions: 4872
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4708
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4860
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6776504000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)