Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_A06
(872 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O75494|FUSIP_HUMAN FUS-interacting serine-arginine-rich ... 73 1e-12
sp|Q8WXF0|SRR35_HUMAN 35 kDa SR repressor protein (SRrp35) 72 3e-12
sp|P27476|NSR1_YEAST Nuclear localization sequence binding ... 57 9e-08
sp|P30352|SFRS2_CHICK Splicing factor, arginine/serine-rich... 57 9e-08
sp|Q6PDU1|SFRS2_RAT Splicing factor, arginine/serine-rich 2... 57 9e-08
sp|Q5R1W5|SFRS2_PANTR Splicing factor, arginine/serine-rich... 57 9e-08
sp|Q09511|RSP4_CAEEL Probable splicing factor, arginine/ser... 55 3e-07
sp|P62997|TRA2B_RAT Arginine/serine-rich splicing factor 10... 51 5e-06
sp|Q9NEW6|RSP3_CAEEL Probable splicing factor, arginine/ser... 50 6e-06
sp|Q13595|TRA2A_HUMAN Transformer-2 protein homolog (TRA-2 ... 50 8e-06
>sp|O75494|FUSIP_HUMAN FUS-interacting serine-arginine-rich protein 1 (TLS-associated
protein with Ser-Arg repeats) (TLS-associated protein
with SR repeats) (TASR) (TLS-associated serine-arginine
protein) (TLS-associated SR protein) (40 kDa
SR-repressor protein) (SRrp40) (Splicing factor SRp38)
sp|Q9R0U0|FUSIP_MOUSE FUS-interacting serine-arginine-rich protein 1 (TLS-associated
protein with Ser-Arg repeats) (TLS-associated protein
with SR repeats) (TASR) (TLS-associated serine-arginine
protein) (TLS-associated SR protein) (Neural-specific SR
protein) (Neural-salient serine/arginine-rich protein)
Length = 262
Score = 72.8 bits (177), Expect = 1e-12
Identities = 33/71 (46%), Positives = 50/71 (70%)
Frame = +1
Query: 364 RRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRLQGYRIGKRSL 543
R ++L+R FGRYG IV +P+D+Y+ P+GFA+VQFED+RDAE++ L I R +
Sbjct: 22 RSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQI 81
Query: 544 RLEFATGTKKS 576
++FA G +K+
Sbjct: 82 EIQFAQGDRKT 92
>sp|Q8WXF0|SRR35_HUMAN 35 kDa SR repressor protein (SRrp35)
Length = 261
Score = 71.6 bits (174), Expect = 3e-12
Identities = 32/71 (45%), Positives = 50/71 (70%)
Frame = +1
Query: 364 RRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRLQGYRIGKRSL 543
R ++L+R FGRYG IV +P+D+Y+ P+GFA+VQFED+RDAE++ L + R +
Sbjct: 22 RPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNLNRKWVCGRQI 81
Query: 544 RLEFATGTKKS 576
++FA G +K+
Sbjct: 82 EIQFAQGDRKT 92
>sp|P27476|NSR1_YEAST Nuclear localization sequence binding protein (P67)
Length = 414
Score = 56.6 bits (135), Expect = 9e-08
Identities = 25/68 (36%), Positives = 43/68 (63%)
Frame = +1
Query: 358 NDRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRLQGYRIGKR 537
N RD + +F ++G +V+ +P + PKGF +VQF ++ DA+++ D LQG I R
Sbjct: 277 NADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEYIDNR 336
Query: 538 SLRLEFAT 561
+RL+F++
Sbjct: 337 PVRLDFSS 344
Score = 33.5 bits (75), Expect = 0.79
Identities = 16/62 (25%), Positives = 32/62 (51%)
Frame = +1
Query: 376 LKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRLQGYRIGKRSLRLEF 555
LK+ F G ++ A + + + +G+ +V FE+ AE++ +QG I R + +
Sbjct: 184 LKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDM 243
Query: 556 AT 561
+T
Sbjct: 244 ST 245
>sp|P30352|SFRS2_CHICK Splicing factor, arginine/serine-rich 2 (Splicing factor SC35)
(SC-35) (Splicing component, 35 kDa) (PR264 protein)
Length = 221
Score = 56.6 bits (135), Expect = 9e-08
Identities = 26/63 (41%), Positives = 40/63 (63%)
Frame = +1
Query: 370 DELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRLQGYRIGKRSLRL 549
D L+R+F +YG + +P D Y+ +GFAFV+F D RDAE++ D + G + R LR+
Sbjct: 28 DTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRV 87
Query: 550 EFA 558
+ A
Sbjct: 88 QMA 90
>sp|Q6PDU1|SFRS2_RAT Splicing factor, arginine/serine-rich 2 (Splicing factor SC35)
(SC-35) (Splicing component, 35 kDa)
sp|Q62093|SFRS2_MOUSE Splicing factor, arginine/serine-rich 2 (Splicing factor SC35)
(SC-35) (Splicing component, 35 kDa) (PR264 protein)
sp|Q01130|SFRS2_HUMAN Splicing factor, arginine/serine-rich 2 (Splicing factor SC35)
(SC-35) (Splicing component, 35 kDa) (PR264 protein)
Length = 221
Score = 56.6 bits (135), Expect = 9e-08
Identities = 26/63 (41%), Positives = 40/63 (63%)
Frame = +1
Query: 370 DELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRLQGYRIGKRSLRL 549
D L+R+F +YG + +P D Y+ +GFAFV+F D RDAE++ D + G + R LR+
Sbjct: 28 DTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRV 87
Query: 550 EFA 558
+ A
Sbjct: 88 QMA 90
>sp|Q5R1W5|SFRS2_PANTR Splicing factor, arginine/serine-rich 2 (Splicing factor SC35)
(SC-35) (Splicing component, 35 kDa)
Length = 221
Score = 56.6 bits (135), Expect = 9e-08
Identities = 26/63 (41%), Positives = 40/63 (63%)
Frame = +1
Query: 370 DELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRLQGYRIGKRSLRL 549
D L+R+F +YG + +P D Y+ +GFAFV+F D RDAE++ D + G + R LR+
Sbjct: 28 DTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRV 87
Query: 550 EFA 558
+ A
Sbjct: 88 QMA 90
>sp|Q09511|RSP4_CAEEL Probable splicing factor, arginine/serine-rich 4 (RNA-binding
protein srp-2) (CeSC35)
Length = 196
Score = 54.7 bits (130), Expect = 3e-07
Identities = 28/63 (44%), Positives = 38/63 (60%)
Frame = +1
Query: 370 DELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRLQGYRIGKRSLRL 549
++L+R F RYG+I +P D YS KGF FV+F + RDAE + DR G + R LR+
Sbjct: 33 NDLRRTFERYGDIGDVHIPRDKYSRQSKGFGFVRFYERRDAEHALDRTDGKLVDGRELRV 92
Query: 550 EFA 558
A
Sbjct: 93 TLA 95
>sp|P62997|TRA2B_RAT Arginine/serine-rich splicing factor 10 (Transformer-2-beta)
(HTRA2-beta) (Transformer 2 protein homolog) (RA301)
sp|P62996|TRA2B_MOUSE Arginine/serine-rich splicing factor 10 (Transformer-2-beta)
(HTRA2-beta) (Transformer 2 protein homolog)
(Silica-induced gene 41 protein) (SIG-41)
sp|P62995|TRA2B_HUMAN Arginine/serine-rich splicing factor 10 (Transformer-2-beta)
(HTRA2-beta) (Transformer 2 protein homolog)
Length = 288
Score = 50.8 bits (120), Expect = 5e-06
Identities = 25/70 (35%), Positives = 43/70 (61%)
Frame = +1
Query: 349 LY*NDRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRLQGYRI 528
LY +R +L+ +F +YG I ++ D S +GFAFV FE++ DA+E+ +R G +
Sbjct: 127 LYTTER--DLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMEL 184
Query: 529 GKRSLRLEFA 558
R +R++F+
Sbjct: 185 DGRRIRVDFS 194
>sp|Q9NEW6|RSP3_CAEEL Probable splicing factor, arginine/serine-rich 3 (CeSF2)
(CeSF2/ASF)
Length = 258
Score = 50.4 bits (119), Expect = 6e-06
Identities = 29/67 (43%), Positives = 37/67 (55%)
Frame = +1
Query: 364 RRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRLQGYRIGKRSL 543
R E++ IF +YG I VD SG FAFV+FED RDAE++ GY R +
Sbjct: 21 REKEVEDIFHKYGRIKY----VDIKSGRGPAFAFVEFEDHRDAEDAVRARDGYEFDGRRI 76
Query: 544 RLEFATG 564
R+EF G
Sbjct: 77 RVEFTRG 83
>sp|Q13595|TRA2A_HUMAN Transformer-2 protein homolog (TRA-2 alpha)
Length = 282
Score = 50.1 bits (118), Expect = 8e-06
Identities = 24/70 (34%), Positives = 42/70 (60%)
Frame = +1
Query: 349 LY*NDRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRLQGYRI 528
LY +R +L+ +F RYG + + D +G +GFAFV FE I D++E+ +R G +
Sbjct: 128 LYTTER--DLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMEL 185
Query: 529 GKRSLRLEFA 558
R +R++++
Sbjct: 186 DGRRIRVDYS 195
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,854,267
Number of Sequences: 369166
Number of extensions: 1384505
Number of successful extensions: 3245
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3057
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3234
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8646143400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)