Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_A02
(550 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99832|TCPH_HUMAN T-complex protein 1, eta subunit (TCP-... 240 1e-63
sp|Q5R5C8|TCPH_PONPY T-complex protein 1, eta subunit (TCP-... 239 2e-63
sp|P80313|TCPH_MOUSE T-complex protein 1, eta subunit (TCP-... 235 5e-62
sp|P87153|TCPH_SCHPO Probable T-complex protein 1, eta subu... 210 2e-54
sp|P42943|TCPH_YEAST T-complex protein 1, eta subunit (TCP-... 186 2e-47
sp|P54409|TCPH_TETPY T-complex protein 1, eta subunit (TCP-... 163 3e-40
sp|O77323|TCPH_PLAF7 T-complex protein 1, eta subunit (TCP-... 157 2e-38
sp|P50016|THS_METKA Thermosome subunit (Chaperonin-like com... 127 2e-29
sp|O28045|THSA_ARCFU Thermosome alpha subunit (Thermosome s... 124 1e-28
sp|P48424|THSA_THEAC Thermosome alpha subunit (Thermosome s... 119 6e-27
>sp|Q99832|TCPH_HUMAN T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta) (HIV-1 Nef
interacting protein)
Length = 543
Score = 240 bits (613), Expect = 1e-63
Identities = 117/164 (71%), Positives = 138/164 (84%)
Frame = +1
Query: 1 EQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDMEISKYLRDYSRNIHGRDQQFIGAM 180
EQFMEETERSLHDAIMIVRRA+KND+VVAGGGAI+ME+SKYLRDYSR I G+ Q IGA
Sbjct: 379 EQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAY 438
Query: 181 ARAFEVIPRQLCENAGFDATNILNKLRQKHAQGKIWCGVDIMNEDIADNFEACVWEPALV 360
A+A E+IPRQLC+NAGFDATNILNKLR +HAQG W GVDI NEDIADNFEA VWEPA+V
Sbjct: 439 AKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWEPAMV 498
Query: 361 KSNAITAATEAACMVLTLDETIRNAKSKTPEDNRPVKMPGRGRP 492
+ NA+TAA+EAAC+++++DETI+N +S + GRGRP
Sbjct: 499 RINALTAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRGRP 542
>sp|Q5R5C8|TCPH_PONPY T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 543
Score = 239 bits (611), Expect = 2e-63
Identities = 117/164 (71%), Positives = 138/164 (84%)
Frame = +1
Query: 1 EQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDMEISKYLRDYSRNIHGRDQQFIGAM 180
EQFMEETERSLHDAIMIVRRA+KND+VVAGGGAI+ME+SKYLRDYSR I G+ Q IGA
Sbjct: 379 EQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAY 438
Query: 181 ARAFEVIPRQLCENAGFDATNILNKLRQKHAQGKIWCGVDIMNEDIADNFEACVWEPALV 360
A+A E+IPRQLC+NAGFDATNILNKLR +HAQG W GVDI NEDIADNFEA VWEPA+V
Sbjct: 439 AKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWEPAMV 498
Query: 361 KSNAITAATEAACMVLTLDETIRNAKSKTPEDNRPVKMPGRGRP 492
+ NA+TAA+EAAC+++++DETI+N +S + GRGRP
Sbjct: 499 RINALTAASEAACLIVSVDETIKNPRSTVDAPAAAGRGRGRGRP 542
>sp|P80313|TCPH_MOUSE T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 544
Score = 235 bits (600), Expect = 5e-62
Identities = 115/163 (70%), Positives = 139/163 (85%)
Frame = +1
Query: 1 EQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDMEISKYLRDYSRNIHGRDQQFIGAM 180
EQFMEETERSLHDAIMIVRRA+KND+VVAGGGAI+ME+SKYLRDYSR I G+ Q IGA
Sbjct: 379 EQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAY 438
Query: 181 ARAFEVIPRQLCENAGFDATNILNKLRQKHAQGKIWCGVDIMNEDIADNFEACVWEPALV 360
A+A E+IPRQLC+NAGFDATNILNKLR +HAQG +W GVDI NE+IADNF+A VWEPA+V
Sbjct: 439 AKALEIIPRQLCDNAGFDATNILNKLRARHAQGGMWYGVDINNENIADNFQAFVWEPAMV 498
Query: 361 KSNAITAATEAACMVLTLDETIRNAKSKTPEDNRPVKMPGRGR 489
+ NA+TAA+EAAC+++++DETI+N +S + P GRGR
Sbjct: 499 RINALTAASEAACLIVSVDETIKNPRSTV---DPPAPSAGRGR 538
>sp|P87153|TCPH_SCHPO Probable T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 558
Score = 210 bits (535), Expect = 2e-54
Identities = 104/174 (59%), Positives = 134/174 (77%), Gaps = 10/174 (5%)
Frame = +1
Query: 1 EQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDMEISKYLRDYSRNIHGRDQQFIGAM 180
+QF+ E ERSLHDAIMIV+ A+KN+ VVAGGGA +ME+SKYLRDYS I G+ Q FI A
Sbjct: 384 DQFIAEVERSLHDAIMIVKHALKNNLVVAGGGACEMELSKYLRDYSLTISGKQQNFIAAF 443
Query: 181 ARAFEVIPRQLCENAGFDATNILNKLRQKHAQGKIWCGVDIMNEDIADNFEACVWEPALV 360
AR+ EVIPRQLC+NAGFD+TNILNKLR +HA+G++W GVD+ +E +A+NFE VWEP+ V
Sbjct: 444 ARSLEVIPRQLCDNAGFDSTNILNKLRMQHAKGEMWAGVDMDSEGVANNFEKFVWEPSTV 503
Query: 361 KSNAITAATEAACMVLTLDETIRNAKSKTPE----------DNRPVKMPGRGRP 492
KSNAI +ATEAA ++L++DETI+N S+ P+ NR ++ GRG P
Sbjct: 504 KSNAILSATEAATLILSVDETIKNEPSQQPQAPQGALPPGAANRIMRGRGRGMP 557
>sp|P42943|TCPH_YEAST T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 550
Score = 186 bits (473), Expect = 2e-47
Identities = 96/164 (58%), Positives = 119/164 (72%), Gaps = 1/164 (0%)
Frame = +1
Query: 1 EQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDMEISKYLRDYSRNIHGRDQQFIGAM 180
EQ + E ERSLHDAIMIV+RA++N +VAGGGA +ME+SK LRDYS+ I G+ Q I A
Sbjct: 383 EQVIAEVERSLHDAIMIVKRALQNKLIVAGGGATEMEVSKCLRDYSKTIAGKQQMIINAF 442
Query: 181 ARAFEVIPRQLCENAGFDATNILNKLRQKHAQGKIWCGVDIMNEDIADNFEACVWEPALV 360
A+A EVIPRQLCENAGFDA ILNKLR H++G+ W GV E+I DNF VWEPALV
Sbjct: 443 AKALEVIPRQLCENAGFDAIEILNKLRLAHSKGEKWYGVVFETENIGDNFAKFVWEPALV 502
Query: 361 KSNAITAATEAACMVLTLDETIRNAKSKTPEDN-RPVKMPGRGR 489
K NA+ +ATEA ++L++DETI N S++ P + GRGR
Sbjct: 503 KINALNSATEATNLILSVDETITNKGSESANAGMMPPQGAGRGR 546
>sp|P54409|TCPH_TETPY T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 558
Score = 163 bits (412), Expect = 3e-40
Identities = 88/156 (56%), Positives = 114/156 (73%), Gaps = 5/156 (3%)
Frame = +1
Query: 1 EQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDMEISKYLRDYSRNIHGRDQQFIGAM 180
EQF+ E ERSL+DAIMIVRR MK + +V GGGAI++EIS+ LR +SR G+ Q I A
Sbjct: 379 EQFIAEAERSLNDAIMIVRRCMKANKIVPGGGAIELEISRLLRLHSRKTEGKVQLVINAF 438
Query: 181 ARAFEVIPRQLCENAGFDATNILNKLRQKHA----QGKIWCGVDIMNED-IADNFEACVW 345
A+A EVIP+ + +NAG D+ +LNKLRQKHA Q K + GVDI D I +NFE VW
Sbjct: 439 AKALEVIPKTIADNAGHDSIQVLNKLRQKHALESDQSKNF-GVDINAVDGIGNNFENFVW 497
Query: 346 EPALVKSNAITAATEAACMVLTLDETIRNAKSKTPE 453
EP +V+ NA +AATEAAC +L++DET+RN KS+ P+
Sbjct: 498 EPIIVRKNAFSAATEAACTILSIDETVRNPKSEQPK 533
>sp|O77323|TCPH_PLAF7 T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta)
Length = 539
Score = 157 bits (397), Expect = 2e-38
Identities = 77/157 (49%), Positives = 111/157 (70%), Gaps = 2/157 (1%)
Frame = +1
Query: 1 EQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDMEISKYLRDYSRNIHGRDQQFIGAM 180
+QF+EE ERS++DAIMIV R + N +V G G+I+M++SKYLR YSR+I ++Q + +
Sbjct: 381 KQFIEEVERSINDAIMIVLRCITNSEIVPGAGSIEMQLSKYLRIYSRSICNKEQIVLFSF 440
Query: 181 ARAFEVIPRQLCENAGFDATNILNKLRQKHAQ--GKIWCGVDIMNEDIADNFEACVWEPA 354
A+A E IPR L NAG+D+T+ILNKLR+KH++ IW GVD M DI + ++ C++E
Sbjct: 441 AKALESIPRHLSHNAGYDSTDILNKLRKKHSEQTSDIWYGVDCMEGDIINAYDNCIFEVT 500
Query: 355 LVKSNAITAATEAACMVLTLDETIRNAKSKTPEDNRP 465
+K N I +ATEAAC++L++DETI+N S P
Sbjct: 501 KIKRNVIYSATEAACLILSIDETIKNPSSAAGTQRSP 537
>sp|P50016|THS_METKA Thermosome subunit (Chaperonin-like complex) (CLIC)
Length = 545
Score = 127 bits (318), Expect = 2e-29
Identities = 61/142 (42%), Positives = 96/142 (67%)
Frame = +1
Query: 1 EQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDMEISKYLRDYSRNIHGRDQQFIGAM 180
E ++E ER++ DAI +V A+++ VVAGGGA ++E+++ LRD++ + GR+Q + A
Sbjct: 383 EHVVDEAERAIEDAIGVVAAALEDGKVVAGGGAPEVEVARQLRDFADGVEGREQLAVEAF 442
Query: 181 ARAFEVIPRQLCENAGFDATNILNKLRQKHAQGKIWCGVDIMNEDIADNFEACVWEPALV 360
A A E+IPR L EN+G D ++L +LR KH G++ G+D+ + D+ D E V EP V
Sbjct: 443 ADALEIIPRTLAENSGLDPIDVLVQLRAKHEDGQVTAGIDVYDGDVKDMLEEGVVEPLRV 502
Query: 361 KSNAITAATEAACMVLTLDETI 426
K+ A+ +ATEAA M+L +D+ I
Sbjct: 503 KTQALASATEAAEMILRIDDVI 524
>sp|O28045|THSA_ARCFU Thermosome alpha subunit (Thermosome subunit 1) (Chaperonin alpha
subunit)
Length = 545
Score = 124 bits (312), Expect = 1e-28
Identities = 69/154 (44%), Positives = 99/154 (64%), Gaps = 3/154 (1%)
Frame = +1
Query: 1 EQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDMEISKYLRDYSRNIHGRDQQFIGAM 180
E ++E ERSL DAI +V+ A+++ VVAGGGA ++E++ +RD++ + GR+Q A
Sbjct: 381 EHVVDEVERSLQDAIKVVKTALESGKVVAGGGAPEIEVALKIRDWAPTLGGREQLAAEAF 440
Query: 181 ARAFEVIPRQLCENAGFDATNILNKLRQKHAQGKIWCGVDIMNEDIADNFEACVWEPALV 360
A A EVIPR L EN+G D +IL +LR+ H +GK GVD+ + ++A E V EP V
Sbjct: 441 ASALEVIPRALAENSGLDPIDILVELRKAHEEGKTTYGVDVFSGEVACMKERGVLEPLKV 500
Query: 361 KSNAITAATEAACMVLTLDETIRN---AKSKTPE 453
K+ AIT+ATE A M+L +D+ I K K PE
Sbjct: 501 KTQAITSATEVAIMILRIDDVIAAKGLEKEKGPE 534
>sp|P48424|THSA_THEAC Thermosome alpha subunit (Thermosome subunit 1) (Chaperonin alpha
subunit)
Length = 545
Score = 119 bits (297), Expect = 6e-27
Identities = 64/166 (38%), Positives = 99/166 (59%), Gaps = 2/166 (1%)
Frame = +1
Query: 1 EQFMEETERSLHDAIMIVRRAMKNDAVVAGGGAIDMEISKYLRDYSRNIHGRDQQFIGAM 180
+ + E ER+L+DAI +V ++ + GGGA++ E++ L Y+ ++ GR+Q I A
Sbjct: 378 DHVVSEVERALNDAIRVVAITKEDGKFLWGGGAVEAELAMRLAKYANSVGGREQLAIEAF 437
Query: 181 ARAFEVIPRQLCENAGFDATNILNKLRQKHAQGKIWCGVDIMNEDIADNFEACVWEPALV 360
A+A E+IPR L ENAG D N L KL+ +H +G+I GVD+ N + D V +P V
Sbjct: 438 AKALEIIPRTLAENAGIDPINTLIKLKAEHEKGRISVGVDLDNNGVGDMKAKGVVDPLRV 497
Query: 361 KSNAITAATEAACMVLTLDETIRNAKSKTP--EDNRPVKMPGRGRP 492
K++A+ +A E A M+L +D+ I + KS P + + MPG G P
Sbjct: 498 KTHALESAVEVATMILRIDDVIASKKSTPPSGQGGQGQGMPGGGMP 543
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,649,944
Number of Sequences: 369166
Number of extensions: 1162798
Number of successful extensions: 3574
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3244
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3316
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3833118120
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)