Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_P13
(742 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9JJ04|B4GT4_MOUSE Beta-1,4-galactosyltransferase 4 (Bet... 173 5e-43
sp|Q66HH1|B4GT4_RAT Beta-1,4-galactosyltransferase 4 (Beta-... 173 5e-43
sp|O60513|B4GT4_HUMAN Beta-1,4-galactosyltransferase 4 (Bet... 172 1e-42
sp|Q80WN7|B4GT4_CRIGR Beta-1,4-galactosyltransferase 4 (Bet... 170 4e-42
sp|Q80WN9|B4GT2_CRIGR Beta-1,4-galactosyltransferase 2 (Bet... 169 5e-42
sp|Q9Z2Y2|B4GT2_MOUSE Beta-1,4-galactosyltransferase 2 (Bet... 168 2e-41
sp|O60909|B4GT2_HUMAN Beta-1,4-galactosyltransferase 2 (Bet... 166 5e-41
sp|P15535|B4GT1_MOUSE Beta-1,4-galactosyltransferase 1 (Bet... 165 1e-40
sp|P15291|B4GT1_HUMAN Beta-1,4-galactosyltransferase 1 (Bet... 164 3e-40
sp|P08037|B4GT1_BOVIN Beta-1,4-galactosyltransferase 1 (Bet... 163 4e-40
>sp|Q9JJ04|B4GT4_MOUSE Beta-1,4-galactosyltransferase 4 (Beta-1,4-GalTase 4) (Beta4Gal-T4)
(b4Gal-T4) (UDP-galactose:beta-N-acetylglucosamine
beta-1,4-galactosyltransferase 4) (UDP-Gal:beta-GlcNAc
beta-1,4-galactosyltransferase 4) [Includes:
N-acetyllactosamine synthase (Nal synthetase);
Beta-N-acetylglucosaminyl-glycolipid
beta-1,4-galactosyltransferase ]
Length = 344
Score = 173 bits (438), Expect = 5e-43
Identities = 85/162 (52%), Positives = 106/162 (65%)
Frame = +3
Query: 12 RFNRAALFNVGYKEALKETSINYDCFIFHDVDLIPTNENNLYKCGSNPLHLSVAIDKFNY 191
+FNRA L NVGY EALKE N+DCF+FHDVDL+P N+ NLY CG P HL V + Y
Sbjct: 167 KFNRAKLLNVGYLEALKEE--NWDCFVFHDVDLVPENDFNLYTCGDQPKHLVVGRNSTGY 224
Query: 192 KLPYNSIFGGAVALSKKQFLKVNGFSNIFYGWGGEDDDMSTRLTAEHYSIARYPNLVARY 371
+L Y+ FGG ALS++QFLKVNGFSN ++GWGGEDDD+ R+ I+R V +Y
Sbjct: 225 RLRYSKYFGGVTALSREQFLKVNGFSNNYWGWGGEDDDLRLRVELHKMKISRPKPDVGKY 284
Query: 372 VMIRHNSDSGNPVNDARWKLLKDSKTRYKIDGISTLDYSIQS 497
MI H D GN VN R KLL+ +K DG+S+ Y + S
Sbjct: 285 TMIFHTRDKGNEVNMGRMKLLQQMSRVWKTDGLSSCSYRLLS 326
>sp|Q66HH1|B4GT4_RAT Beta-1,4-galactosyltransferase 4 (Beta-1,4-GalTase 4) (Beta4Gal-T4)
(b4Gal-T4) (UDP-galactose:beta-N-acetylglucosamine
beta-1,4-galactosyltransferase 4) (UDP-Gal:beta-GlcNAc
beta-1,4-galactosyltransferase 4) [Includes:
N-acetyllactosamine synthase (Nal synthetase);
Beta-N-acetylglucosaminyl-glycolipid
beta-1,4-galactosyltransferase ]
Length = 344
Score = 173 bits (438), Expect = 5e-43
Identities = 85/162 (52%), Positives = 106/162 (65%)
Frame = +3
Query: 12 RFNRAALFNVGYKEALKETSINYDCFIFHDVDLIPTNENNLYKCGSNPLHLSVAIDKFNY 191
+FNRA L NVGY EALKE N+DCFIFHDVDL+P N+ NLY CG P HL V + Y
Sbjct: 167 KFNRAKLLNVGYLEALKEE--NWDCFIFHDVDLVPENDFNLYTCGDQPKHLVVGRNSTGY 224
Query: 192 KLPYNSIFGGAVALSKKQFLKVNGFSNIFYGWGGEDDDMSTRLTAEHYSIARYPNLVARY 371
+L Y+ FGG ALS++QF KVNGFSN ++GWGGEDDD+ R+ I+R V +Y
Sbjct: 225 RLRYSKYFGGVTALSREQFFKVNGFSNNYWGWGGEDDDLRLRVELHKMKISRPKPDVGKY 284
Query: 372 VMIRHNSDSGNPVNDARWKLLKDSKTRYKIDGISTLDYSIQS 497
MI H D GN VN +R KLL+ +K DG+S+ Y + S
Sbjct: 285 TMIFHTRDKGNEVNGSRMKLLQQMSRVWKTDGLSSCSYRLLS 326
>sp|O60513|B4GT4_HUMAN Beta-1,4-galactosyltransferase 4 (Beta-1,4-GalTase 4) (Beta4Gal-T4)
(b4Gal-T4) (UDP-galactose:beta-N-acetylglucosamine
beta-1,4-galactosyltransferase 4) (UDP-Gal:beta-GlcNAc
beta-1,4-galactosyltransferase 4) [Includes:
N-acetyllactosamine synthase (Nal synthetase);
Beta-N-acetylglucosaminyl-glycolipid
beta-1,4-galactosyltransferase ]
Length = 344
Score = 172 bits (435), Expect = 1e-42
Identities = 84/164 (51%), Positives = 107/164 (65%)
Frame = +3
Query: 6 GTRFNRAALFNVGYKEALKETSINYDCFIFHDVDLIPTNENNLYKCGSNPLHLSVAIDKF 185
G +FNRA L NVGY EALKE N+DCFIFHDVDL+P N+ NLYKC +P HL V +
Sbjct: 165 GKKFNRAKLLNVGYLEALKEE--NWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNST 222
Query: 186 NYKLPYNSIFGGAVALSKKQFLKVNGFSNIFYGWGGEDDDMSTRLTAEHYSIARYPNLVA 365
Y+L Y+ FGG ALS++QF KVNGFSN ++GWGGEDDD+ R+ + I+R V
Sbjct: 223 GYRLRYSGYFGGVTALSREQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVG 282
Query: 366 RYVMIRHNSDSGNPVNDARWKLLKDSKTRYKIDGISTLDYSIQS 497
+Y M+ H D GN VN R KLL ++ DG+S+ Y + S
Sbjct: 283 KYTMVFHTRDKGNEVNAERMKLLHQVSRVWRTDGLSSCSYKLVS 326
>sp|Q80WN7|B4GT4_CRIGR Beta-1,4-galactosyltransferase 4 (Beta-1,4-GalTase 4) (Beta4Gal-T4)
(b4Gal-T4) (UDP-galactose:beta-N-acetylglucosamine
beta-1,4-galactosyltransferase 4) (UDP-Gal:beta-GlcNAc
beta-1,4-galactosyltransferase 4) [Includes:
N-acetyllactosamine synthase (Nal synthetase);
Beta-N-acetylglucosaminyl-glycolipid
beta-1,4-galactosyltransferase ]
Length = 344
Score = 170 bits (430), Expect = 4e-42
Identities = 85/162 (52%), Positives = 104/162 (64%)
Frame = +3
Query: 12 RFNRAALFNVGYKEALKETSINYDCFIFHDVDLIPTNENNLYKCGSNPLHLSVAIDKFNY 191
+FNRA L NVGY EALKE N+DCFIFHDVDL+P N+ NLY CG P HL V + Y
Sbjct: 167 KFNRAKLLNVGYLEALKEQ--NWDCFIFHDVDLVPENDFNLYTCGDQPKHLVVGRNSTGY 224
Query: 192 KLPYNSIFGGAVALSKKQFLKVNGFSNIFYGWGGEDDDMSTRLTAEHYSIARYPNLVARY 371
+L Y+ FGG ALS++QF KVNGFSN ++GWGGEDDD+ R+ I+R V +Y
Sbjct: 225 RLRYSKYFGGVTALSREQFFKVNGFSNNYWGWGGEDDDLRLRVELHKMKISRPNPDVGKY 284
Query: 372 VMIRHNSDSGNPVNDARWKLLKDSKTRYKIDGISTLDYSIQS 497
MI H D GN VN R KLL +K DG+S+ Y + S
Sbjct: 285 TMIFHTRDKGNEVNVDRMKLLHQMSRVWKTDGLSSCSYRLLS 326
>sp|Q80WN9|B4GT2_CRIGR Beta-1,4-galactosyltransferase 2 (Beta-1,4-GalTase 2) (Beta4Gal-T2)
(b4Gal-T2) (UDP-galactose:beta-N-acetylglucosamine
beta-1,4-galactosyltransferase 2) (UDP-Gal:beta-GlcNAc
beta-1,4-galactosyltransferase 2) [Includes: Lactose
synthase A protein ; N-acetyllactosamine synthase (Nal
synthetase); Beta-N-acetylglucosaminylglycopeptide
beta-1,4-galactosyltransferase ;
Beta-N-acetylglucosaminyl-glycolipid
beta-1,4-galactosyltransferase ]
Length = 369
Score = 169 bits (429), Expect = 5e-42
Identities = 79/159 (49%), Positives = 108/159 (67%)
Frame = +3
Query: 15 FNRAALFNVGYKEALKETSINYDCFIFHDVDLIPTNENNLYKCGSNPLHLSVAIDKFNYK 194
FNRA L NVG+ EALKE + YDCFIF DVDL+P ++ NLY+CG P H ++A+DKF ++
Sbjct: 186 FNRAKLLNVGFLEALKEDA-TYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFR 244
Query: 195 LPYNSIFGGAVALSKKQFLKVNGFSNIFYGWGGEDDDMSTRLTAEHYSIARYPNLVARYV 374
LPY S FGG LSK QFL++NGF N ++GWGGEDDD+ R++ I+R + RY
Sbjct: 245 LPYASYFGGVSGLSKAQFLRINGFPNEYWGWGGEDDDIFNRISLTGMKISRPDVRIGRYR 304
Query: 375 MIRHNSDSGNPVNDARWKLLKDSKTRYKIDGISTLDYSI 491
MI+H+ D N N R+ ++++K K DGI +L Y +
Sbjct: 305 MIKHDRDKHNEPNPQRFSKIQNTKLSMKWDGIGSLRYRV 343
>sp|Q9Z2Y2|B4GT2_MOUSE Beta-1,4-galactosyltransferase 2 (Beta-1,4-GalTase 2) (Beta4Gal-T2)
(b4Gal-T2) (UDP-galactose:beta-N-acetylglucosamine
beta-1,4-galactosyltransferase 2) (UDP-Gal:beta-GlcNAc
beta-1,4-galactosyltransferase 2) [Includes: Lactose
synthase A protein ; N-acetyllactosamine synthase (Nal
synthetase); Beta-N-acetylglucosaminylglycopeptide
beta-1,4-galactosyltransferase ;
Beta-N-acetylglucosaminyl-glycolipid
beta-1,4-galactosyltransferase ]
Length = 369
Score = 168 bits (425), Expect = 2e-41
Identities = 78/159 (49%), Positives = 108/159 (67%)
Frame = +3
Query: 15 FNRAALFNVGYKEALKETSINYDCFIFHDVDLIPTNENNLYKCGSNPLHLSVAIDKFNYK 194
FNRA L NVG+ EALKE + YDCFIF DVDL+P ++ NLY+CG P H ++A+DKF ++
Sbjct: 186 FNRAKLLNVGFLEALKEDAA-YDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFR 244
Query: 195 LPYNSIFGGAVALSKKQFLKVNGFSNIFYGWGGEDDDMSTRLTAEHYSIARYPNLVARYV 374
LPY S FGG LSK QFL++NGF N ++GWGGEDDD+ R++ I+R + RY
Sbjct: 245 LPYASYFGGVSGLSKAQFLRINGFPNEYWGWGGEDDDIFNRISLTGMKISRPDVRIGRYR 304
Query: 375 MIRHNSDSGNPVNDARWKLLKDSKTRYKIDGISTLDYSI 491
MI+H+ D N N R+ ++++K K DGI ++ Y +
Sbjct: 305 MIKHDRDKHNEPNPQRFNKIQNTKMSMKWDGIGSVRYRV 343
>sp|O60909|B4GT2_HUMAN Beta-1,4-galactosyltransferase 2 (Beta-1,4-GalTase 2) (Beta4Gal-T2)
(b4Gal-T2) (UDP-galactose:beta-N-acetylglucosamine
beta-1,4-galactosyltransferase 2) (UDP-Gal:beta-GlcNAc
beta-1,4-galactosyltransferase 2) [Includes: Lactose
synthase A protein ; N-acetyllactosamine synthase (Nal
synthetase); Beta-N-acetylglucosaminylglycopeptide
beta-1,4-galactosyltransferase ;
Beta-N-acetylglucosaminyl-glycolipid
beta-1,4-galactosyltransferase ]
Length = 372
Score = 166 bits (421), Expect = 5e-41
Identities = 77/159 (48%), Positives = 107/159 (67%)
Frame = +3
Query: 15 FNRAALFNVGYKEALKETSINYDCFIFHDVDLIPTNENNLYKCGSNPLHLSVAIDKFNYK 194
FNRA L NVG+ EALKE + YDCFIF DVDL+P ++ NLY+CG P H ++A+DKF ++
Sbjct: 189 FNRAKLLNVGFLEALKEDAA-YDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFR 247
Query: 195 LPYNSIFGGAVALSKKQFLKVNGFSNIFYGWGGEDDDMSTRLTAEHYSIARYPNLVARYV 374
LPY FGG LSK QFL++NGF N ++GWGGEDDD+ R++ I+R + RY
Sbjct: 248 LPYAGYFGGVSGLSKAQFLRINGFPNEYWGWGGEDDDIFNRISLTGMKISRPDIRIGRYR 307
Query: 375 MIRHNSDSGNPVNDARWKLLKDSKTRYKIDGISTLDYSI 491
MI+H+ D N N R+ ++++K K DGI ++ Y +
Sbjct: 308 MIKHDRDKHNEPNPQRFTKIQNTKLTMKRDGIGSVRYQV 346
>sp|P15535|B4GT1_MOUSE Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase 1) (Beta4Gal-T1)
(b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine
beta-1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc
beta-1,4-galactosyltransferase 1) [Includes: Lactose
synthase A protein ; N-acetyllactosamine synthase (Nal
synthetase); Beta-N-acetylglucosaminylglycopeptide
beta-1,4-galactosyltransferase ;
Beta-N-acetylglucosaminyl-glycolipid
beta-1,4-galactosyltransferase ]
Length = 399
Score = 165 bits (418), Expect = 1e-40
Identities = 79/161 (49%), Positives = 109/161 (67%)
Frame = +3
Query: 9 TRFNRAALFNVGYKEALKETSINYDCFIFHDVDLIPTNENNLYKCGSNPLHLSVAIDKFN 188
T FNRA L N+G++EALK+ +Y+CF+F DVDLIP ++ N Y+C S P H+SVA+DKF
Sbjct: 221 TMFNRAKLLNIGFQEALKD--YDYNCFVFSDVDLIPMDDRNAYRCFSQPRHISVAMDKFG 278
Query: 189 YKLPYNSIFGGAVALSKKQFLKVNGFSNIFYGWGGEDDDMSTRLTAEHYSIARYPNLVAR 368
+ LPY FGG ALSK+QFL +NGF N ++GWGGEDDD+ RL + SI+R +V R
Sbjct: 279 FSLPYVQYFGGVSALSKQQFLAINGFPNNYWGWGGEDDDIFNRLVHKGMSISRPNAVVGR 338
Query: 369 YVMIRHNSDSGNPVNDARWKLLKDSKTRYKIDGISTLDYSI 491
MIRH+ D N N R+ + +K + DG+++L Y +
Sbjct: 339 CRMIRHSRDKKNEPNPQRFDRIAHTKETMRFDGLNSLTYKV 379
>sp|P15291|B4GT1_HUMAN Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase 1) (Beta4Gal-T1)
(b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine
beta-1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc
beta-1,4-galactosyltransferase 1) [Includes: Lactose
synthase A protein ; N-acetyllactosamine synthase (Nal
synthetase); Beta-N-acetylglucosaminylglycopeptide
beta-1,4-galactosyltransferase ;
Beta-N-acetylglucosaminyl-glycolipid
beta-1,4-galactosyltransferase ]
Length = 397
Score = 164 bits (414), Expect = 3e-40
Identities = 81/161 (50%), Positives = 107/161 (66%)
Frame = +3
Query: 9 TRFNRAALFNVGYKEALKETSINYDCFIFHDVDLIPTNENNLYKCGSNPLHLSVAIDKFN 188
T FNRA L NVG++EALK+ +Y CF+F DVDLIP N++N Y+C S P H+SVA+DKF
Sbjct: 219 TIFNRAKLLNVGFQEALKD--YDYTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFG 276
Query: 189 YKLPYNSIFGGAVALSKKQFLKVNGFSNIFYGWGGEDDDMSTRLTAEHYSIARYPNLVAR 368
+ LPY FGG ALSK+QFL +NGF N ++GWGGEDDD+ RL SI+R +V R
Sbjct: 277 FSLPYVQYFGGVSALSKQQFLTINGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGR 336
Query: 369 YVMIRHNSDSGNPVNDARWKLLKDSKTRYKIDGISTLDYSI 491
MIRH+ D N N R+ + +K DG+++L Y +
Sbjct: 337 CRMIRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYQV 377
>sp|P08037|B4GT1_BOVIN Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase 1) (Beta4Gal-T1)
(b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine
beta-1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc
beta-1,4-galactosyltransferase 1) [Includes: Lactose
synthase A protein ; N-acetyllactosamine synthase (Nal
synthetase); Beta-N-acetylglucosaminylglycopeptide
beta-1,4-galactosyltransferase ;
Beta-N-acetylglucosaminyl-glycolipid
beta-1,4-galactosyltransferase ]
Length = 402
Score = 163 bits (413), Expect = 4e-40
Identities = 78/159 (49%), Positives = 107/159 (67%)
Frame = +3
Query: 15 FNRAALFNVGYKEALKETSINYDCFIFHDVDLIPTNENNLYKCGSNPLHLSVAIDKFNYK 194
FNRA L NVG+KEALK+ +Y+CF+F DVDLIP N++N Y+C S P H+SVA+DKF +
Sbjct: 226 FNRAKLLNVGFKEALKD--YDYNCFVFSDVDLIPMNDHNTYRCFSQPRHISVAMDKFGFS 283
Query: 195 LPYNSIFGGAVALSKKQFLKVNGFSNIFYGWGGEDDDMSTRLTAEHYSIARYPNLVARYV 374
LPY FGG ALSK+QFL +NGF N ++GWGGEDDD+ RL S++R ++ +
Sbjct: 284 LPYVQYFGGVSALSKQQFLSINGFPNNYWGWGGEDDDIYNRLAFRGMSVSRPNAVIGKCR 343
Query: 375 MIRHNSDSGNPVNDARWKLLKDSKTRYKIDGISTLDYSI 491
MIRH+ D N N R+ + +K DG+++L Y +
Sbjct: 344 MIRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYMV 382
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,550,300
Number of Sequences: 369166
Number of extensions: 1269290
Number of successful extensions: 3186
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3070
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3146
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6679696800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)