Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_P07
(810 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q14693|LPIN1_HUMAN Lipin-1 134 3e-31
sp|Q92539|LPIN2_HUMAN Lipin-2 132 1e-30
sp|Q99PI5|LPIN2_MOUSE Lipin-2 132 1e-30
sp|Q91ZP3|LPIN1_MOUSE Lipin-1 (Fatty liver dystrophy protein) 132 1e-30
sp|Q9BQK8|LPIN3_HUMAN Lipin-3 (Lipin 3-like) 126 6e-29
sp|Q99PI4|LPIN3_MOUSE Lipin-3 125 1e-28
sp|Q7TNN8|LPIN3_MUSSP Lipin-3 125 1e-28
sp|Q9UUJ6|NED1_SCHPO Nuclear elongation and deformation pro... 117 5e-26
sp|P32567|SMP2_YEAST SMP2 protein 107 5e-23
sp|P15205|MAP1B_RAT Microtubule-associated protein 1B (MAP ... 34 0.41
>sp|Q14693|LPIN1_HUMAN Lipin-1
Length = 890
Score = 134 bits (337), Expect = 3e-31
Identities = 67/133 (50%), Positives = 86/133 (64%), Gaps = 1/133 (0%)
Frame = +1
Query: 7 LPDGPILLSPTSLFQSLHREVIEKKPEYFKIQCLNDVRSLFPENTHPLYAGFGNRVNDVI 186
LP GP+LLSP+SLF +LHREVIEKKPE FK+QCL D+++LF NT P YA FGNR DV
Sbjct: 747 LPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVY 806
Query: 187 AYKGVGIDPKRIFTVNPEGSLKNEYCQKWSTSYGNLFDVADHFFQFQSNHDKSRIDYALE 366
+YK VG+ RIFTVNP+G L E+ + +SY L +V DH F S D+
Sbjct: 807 SYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSS--DFPCS 864
Query: 367 D-YIDINYWSSPI 402
D + + +W P+
Sbjct: 865 DTFSNFTFWREPL 877
>sp|Q92539|LPIN2_HUMAN Lipin-2
Length = 896
Score = 132 bits (332), Expect = 1e-30
Identities = 65/137 (47%), Positives = 87/137 (63%)
Frame = +1
Query: 7 LPDGPILLSPTSLFQSLHREVIEKKPEYFKIQCLNDVRSLFPENTHPLYAGFGNRVNDVI 186
LP GP++LSP+SLF + HREVIEKKPE FKI+CLND+++LF + P YA FGNR NDV
Sbjct: 758 LPRGPLMLSPSSLFSAFHREVIEKKPEKFKIECLNDIKNLFAPSKQPFYAAFGNRPNDVY 817
Query: 187 AYKGVGIDPKRIFTVNPEGSLKNEYCQKWSTSYGNLFDVADHFFQFQSNHDKSRIDYALE 366
AY VG+ RIFTVNP+G L E + +SY L ++ +H F S S +
Sbjct: 818 AYTQVGVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFPLLSKEQNSA--FPCP 875
Query: 367 DYIDINYWSSPINELNI 417
++ YW PI E+++
Sbjct: 876 EFSSFCYWRDPIPEVDL 892
>sp|Q99PI5|LPIN2_MOUSE Lipin-2
Length = 893
Score = 132 bits (332), Expect = 1e-30
Identities = 65/137 (47%), Positives = 87/137 (63%)
Frame = +1
Query: 7 LPDGPILLSPTSLFQSLHREVIEKKPEYFKIQCLNDVRSLFPENTHPLYAGFGNRVNDVI 186
LP GP++LSP+SLF + HREVIEKKPE FKI+CLND+++LF + P YA FGNR NDV
Sbjct: 755 LPRGPLMLSPSSLFSAFHREVIEKKPEKFKIECLNDIKNLFAPSRQPFYAAFGNRPNDVY 814
Query: 187 AYKGVGIDPKRIFTVNPEGSLKNEYCQKWSTSYGNLFDVADHFFQFQSNHDKSRIDYALE 366
AY VG+ RIFTVNP+G L E + +SY L ++ +H F S S +
Sbjct: 815 AYTQVGVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFPLLSKEQNSA--FPCP 872
Query: 367 DYIDINYWSSPINELNI 417
++ YW PI +L++
Sbjct: 873 EFSSFCYWRDPIPDLDL 889
>sp|Q91ZP3|LPIN1_MOUSE Lipin-1 (Fatty liver dystrophy protein)
Length = 924
Score = 132 bits (332), Expect = 1e-30
Identities = 66/133 (49%), Positives = 85/133 (63%), Gaps = 1/133 (0%)
Frame = +1
Query: 7 LPDGPILLSPTSLFQSLHREVIEKKPEYFKIQCLNDVRSLFPENTHPLYAGFGNRVNDVI 186
LP GP+LLSP+SLF +LHREVIEKKPE FK+QCL D+++LF NT P YA FGNR DV
Sbjct: 781 LPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVY 840
Query: 187 AYKGVGIDPKRIFTVNPEGSLKNEYCQKWSTSYGNLFDVADHFFQFQSNHDKSRIDYALE 366
+YK VG+ RIFTVNP+G L E+ + +SY L +V DH F D+
Sbjct: 841 SYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKR--SHSCDFPCS 898
Query: 367 D-YIDINYWSSPI 402
D + + +W P+
Sbjct: 899 DTFSNFTFWREPL 911
>sp|Q9BQK8|LPIN3_HUMAN Lipin-3 (Lipin 3-like)
Length = 851
Score = 126 bits (317), Expect = 6e-29
Identities = 64/137 (46%), Positives = 86/137 (62%)
Frame = +1
Query: 7 LPDGPILLSPTSLFQSLHREVIEKKPEYFKIQCLNDVRSLFPENTHPLYAGFGNRVNDVI 186
LP GPILLSP+SLF +LHREVIEKKPE FK+ CL+D++ LF + P YA FGNR NDV
Sbjct: 713 LPKGPILLSPSSLFSALHREVIEKKPEVFKVACLSDIQQLFLPHGQPFYAAFGNRPNDVF 772
Query: 187 AYKGVGIDPKRIFTVNPEGSLKNEYCQKWSTSYGNLFDVADHFFQFQSNHDKSRIDYALE 366
AY+ VG+ RIFTVNP G L E + ++Y L +V + F + + D A
Sbjct: 773 AYRQVGLPESRIFTVNPRGELIQELIKNHKSTYERLGEVVELLFPPVARGPST--DLANP 830
Query: 367 DYIDINYWSSPINELNI 417
+Y + YW P+ +++
Sbjct: 831 EYSNFCYWREPLPAVDL 847
>sp|Q99PI4|LPIN3_MOUSE Lipin-3
Length = 848
Score = 125 bits (315), Expect = 1e-28
Identities = 63/132 (47%), Positives = 83/132 (62%)
Frame = +1
Query: 7 LPDGPILLSPTSLFQSLHREVIEKKPEYFKIQCLNDVRSLFPENTHPLYAGFGNRVNDVI 186
LP GPILLSP+SLF +LHREVIEKKPE FK+ CL+D++ LF P +A FGNR NDV
Sbjct: 710 LPKGPILLSPSSLFSALHREVIEKKPEVFKVACLSDIQQLFLPQRQPFHAAFGNRPNDVF 769
Query: 187 AYKGVGIDPKRIFTVNPEGSLKNEYCQKWSTSYGNLFDVADHFFQFQSNHDKSRIDYALE 366
AY+ VG+ RIFTVNP G L E + ++Y L +V + F + D A
Sbjct: 770 AYRQVGLPESRIFTVNPRGELIQELIKSHKSTYQRLGEVVELLFPPVVRGPST--DLASP 827
Query: 367 DYIDINYWSSPI 402
+Y +++YW P+
Sbjct: 828 EYSNLSYWRKPL 839
>sp|Q7TNN8|LPIN3_MUSSP Lipin-3
Length = 847
Score = 125 bits (315), Expect = 1e-28
Identities = 63/132 (47%), Positives = 83/132 (62%)
Frame = +1
Query: 7 LPDGPILLSPTSLFQSLHREVIEKKPEYFKIQCLNDVRSLFPENTHPLYAGFGNRVNDVI 186
LP GPILLSP+SLF +LHREVIEKKPE FK+ CL+D++ LF P +A FGNR NDV
Sbjct: 709 LPKGPILLSPSSLFSALHREVIEKKPEVFKVACLSDIQQLFLPQRQPFHAAFGNRPNDVF 768
Query: 187 AYKGVGIDPKRIFTVNPEGSLKNEYCQKWSTSYGNLFDVADHFFQFQSNHDKSRIDYALE 366
AY+ VG+ RIFTVNP G L E + ++Y L +V + F + D A
Sbjct: 769 AYRQVGLPESRIFTVNPRGELIQELIKSHKSTYQRLGEVVELLFPPVVRGPST--DLASP 826
Query: 367 DYIDINYWSSPI 402
+Y +++YW P+
Sbjct: 827 EYSNLSYWRKPL 838
>sp|Q9UUJ6|NED1_SCHPO Nuclear elongation and deformation protein 1
Length = 656
Score = 117 bits (292), Expect = 5e-26
Identities = 62/151 (41%), Positives = 89/151 (58%), Gaps = 4/151 (2%)
Frame = +1
Query: 7 LPDGPILLSPTSLFQSLHREVIEKKPEYFKIQCLNDVRSLF--PENTHPLYAGFGNRVND 180
LPDGP++LSP +LHREVI +KPE FK+ CL D+ ++F P P YAGFGNR+ D
Sbjct: 452 LPDGPVILSPDRTMAALHREVILRKPEVFKMACLRDLCNIFALPVPRTPFYAGFGNRITD 511
Query: 181 VIAYKGVGIDPKRIFTVNPEGSLKNEYCQK--WSTSYGNLFDVADHFFQFQSNHDKSRID 354
I+Y V + P RIFT+N G + E Q+ +SY + ++ DHFF + +
Sbjct: 512 AISYNHVRVPPTRIFTINSAGEVHIELLQRSGHRSSYVYMNELVDHFFPPIEVSTRDEV- 570
Query: 355 YALEDYIDINYWSSPINELNIREEINKSKPT 447
+ D+N+W SP+ EL+ EE + +K T
Sbjct: 571 ---SSFTDVNFWRSPLLELSDEEEDDTNKST 598
>sp|P32567|SMP2_YEAST SMP2 protein
Length = 862
Score = 107 bits (266), Expect = 5e-23
Identities = 54/117 (46%), Positives = 75/117 (64%), Gaps = 12/117 (10%)
Frame = +1
Query: 4 KLPDGPILLSPTSLFQSLHREVIEKKPEYFKIQCLNDVRSLF----------PENTHPLY 153
KLP+GP++LSP +L REVI KKPE FKI CLND+RSL+ E + P +
Sbjct: 466 KLPNGPVILSPDRTMAALRREVILKKPEVFKIACLNDIRSLYFEDSDNEVDTEEKSTPFF 525
Query: 154 AGFGNRVNDVIAYKGVGIDPKRIFTVNPEGSLKNEYCQ--KWSTSYGNLFDVADHFF 318
AGFGNR+ D ++Y+ VGI RIFT+N EG + E + + +SY ++ ++ DHFF
Sbjct: 526 AGFGNRITDALSYRTVGIPSSRIFTINTEGEVHMELLELAGYRSSYIHINELVDHFF 582
>sp|P15205|MAP1B_RAT Microtubule-associated protein 1B (MAP 1B) (Neuraxin) [Contains:
MAP1 light chain LC1]
Length = 2459
Score = 34.3 bits (77), Expect = 0.41
Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +1
Query: 91 FKIQCLNDVRSLFPENTHPLYAGFGNRVNDVIAYKGVGIDPKRIFTVNPEGSLK--NEYC 264
F +Q LN + S+ PE PL+ GN + VI ++ +G+ +++ +NP S K +
Sbjct: 382 FTLQYLNKL-SMKPE---PLFRSVGNAIEPVILFQKMGVGKLKMYVLNPVKSSKEMQYFM 437
Query: 265 QKWS 276
Q+W+
Sbjct: 438 QQWT 441
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,897,987
Number of Sequences: 369166
Number of extensions: 1380036
Number of successful extensions: 3559
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3489
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3555
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7715018400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)