Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_P03
(783 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P27615|SCRB2_RAT Lysosome membrane protein II (LIMP II) ... 186 6e-47
sp|Q14108|SCRB2_HUMAN Lysosome membrane protein II (LIMP II... 183 5e-46
sp|O35114|SCRB2_MOUSE Lysosome membrane protein II (LIMP II... 179 8e-45
sp|P97943|SCRB1_RAT Scavenger receptor class B member 1 (SR... 167 3e-41
sp|Q60417|SCRB1_CRIGR Scavenger receptor class B member 1 (... 164 3e-40
sp|Q61009|SCRB1_MOUSE Scavenger receptor class B member 1 (... 164 3e-40
sp|P70110|CD36_MESAU Platelet glycoprotein IV (GPIV) (GPIII... 159 1e-38
sp|Q8SQC1|SCRB1_PIG Scavenger receptor class B member 1 (SR... 157 4e-38
sp|P16671|CD36_HUMAN Platelet glycoprotein IV (GPIV) (Glyco... 155 1e-37
sp|O18824|SCRB1_BOVIN Scavenger receptor class B member 1 (... 155 2e-37
>sp|P27615|SCRB2_RAT Lysosome membrane protein II (LIMP II) (Scavenger receptor class B
member 2) (85 kDa lysosomal membrane sialoglycoprotein)
(LGP85) (CD36 antigen-like 2)
Length = 478
Score = 186 bits (472), Expect = 6e-47
Identities = 93/212 (43%), Positives = 133/212 (62%), Gaps = 2/212 (0%)
Frame = +1
Query: 1 IERWNGSNHISMWNDKYANMINGTDGSMFAPYLNRSSRLYIFQSDICRSIYATYVGSEEI 180
I WNG + W NMINGTDG F P +++ LYIF SD CRS+Y T+ E +
Sbjct: 228 IVEWNGKTSLDWWTTDTCNMINGTDGDSFHPLISKDETLYIFPSDFCRSVYITFSSFENV 287
Query: 181 KGVPSMNYAAPDSVFANHSVNPDNEGFCL-DGDCMGAGVLNLSKCVPGGAPIIMSQPHFY 357
+G+P+ Y P + AN S +N GFC+ +G+CM AGVLN+S C GAPIIMS PHFY
Sbjct: 288 EGLPAFRYKVPAEILANSS---ENAGFCIPEGNCMDAGVLNVSIC-KNGAPIIMSFPHFY 343
Query: 358 SAAEKYIDAVYGINPS-SEFKTILKLEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNISS 534
A EK++ A+ G+ P+ E ++ + + P TG+ L+ AK+ QIN +K + DF + NI +
Sbjct: 344 QADEKFVSAIKGMRPNKEEHESFVDINPLTGIILRGAKRFQINTYVKKLDDFVETGNIRT 403
Query: 535 VVLPMMWLNESVLISDALAGTIRSTLVLPVLV 630
+V P+M+LNESVLI A ++S + ++V
Sbjct: 404 MVFPVMYLNESVLIDKETASQLKSVINTTLIV 435
>sp|Q14108|SCRB2_HUMAN Lysosome membrane protein II (LIMP II) (Scavenger receptor class B
member 2) (85 kDa lysosomal membrane sialoglycoprotein)
(LGP85) (CD36 antigen-like 2)
Length = 478
Score = 183 bits (464), Expect = 5e-46
Identities = 90/212 (42%), Positives = 134/212 (63%), Gaps = 2/212 (0%)
Frame = +1
Query: 1 IERWNGSNHISMWNDKYANMINGTDGSMFAPYLNRSSRLYIFQSDICRSIYATYVGSEEI 180
I WNG + W NMINGTDG F P + + LY+F SD CRS+Y T+ E +
Sbjct: 228 IVEWNGKTSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESV 287
Query: 181 KGVPSMNYAAPDSVFANHSVNPDNEGFCL-DGDCMGAGVLNLSKCVPGGAPIIMSQPHFY 357
+G+P+ Y P + AN S DN GFC+ +G+C+G+GVLN+S C GAPIIMS PHFY
Sbjct: 288 QGLPAFRYKVPAEILANTS---DNAGFCIPEGNCLGSGVLNVSIC-KNGAPIIMSFPHFY 343
Query: 358 SAAEKYIDAVYGINPSSE-FKTILKLEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNISS 534
A E+++ A+ G++P+ E +T + + P TG+ L+ AK+ QINI +K + DF + +I +
Sbjct: 344 QADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRT 403
Query: 535 VVLPMMWLNESVLISDALAGTIRSTLVLPVLV 630
+V P+M+LNESV I A ++S + +++
Sbjct: 404 MVFPVMYLNESVHIDKETASRLKSMINTTLII 435
>sp|O35114|SCRB2_MOUSE Lysosome membrane protein II (LIMP II) (Scavenger receptor class B
member 2) (85 kDa lysosomal membrane sialoglycoprotein)
(LGP85)
Length = 478
Score = 179 bits (454), Expect = 8e-45
Identities = 88/212 (41%), Positives = 135/212 (63%), Gaps = 2/212 (0%)
Frame = +1
Query: 1 IERWNGSNHISMWNDKYANMINGTDGSMFAPYLNRSSRLYIFQSDICRSIYATYVGSEEI 180
I WNG + W NMINGTDG F P +++ LY+F SD+CRS++ T+ E +
Sbjct: 228 IVEWNGKTSLDWWTTDTCNMINGTDGDSFHPLISKDEVLYLFPSDLCRSVHITFSSFENV 287
Query: 181 KGVPSMNYAAPDSVFANHSVNPDNEGFCL-DGDCMGAGVLNLSKCVPGGAPIIMSQPHFY 357
+G+P+ Y P + AN S +N GFC+ +G+CM +GVLN+S C GAPIIMS PHFY
Sbjct: 288 EGLPAFRYKVPAEILANTS---ENAGFCIPEGNCMDSGVLNISIC-KNGAPIIMSFPHFY 343
Query: 358 SAAEKYIDAVYGINPS-SEFKTILKLEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNISS 534
A EK++ A+ G++P+ E ++ + + P TG+ L+ AK+ QIN ++ + DF + +I +
Sbjct: 344 QADEKFVSAIKGMHPNKEEHESFVDINPLTGIILRGAKRFQINTYVRKLDDFVETGDIRT 403
Query: 535 VVLPMMWLNESVLISDALAGTIRSTLVLPVLV 630
+V P+M+LNESVLI A ++S + ++V
Sbjct: 404 MVFPVMYLNESVLIDKETANQLKSVINTTLVV 435
>sp|P97943|SCRB1_RAT Scavenger receptor class B member 1 (SRB1) (SR-BI)
Length = 509
Score = 167 bits (423), Expect = 3e-41
Identities = 82/207 (39%), Positives = 124/207 (59%), Gaps = 1/207 (0%)
Frame = +1
Query: 1 IERWNGSNHISMWNDKYANMINGTDGSMFAPYLNRSSRLYIFQSDICRSIYATYVGSEEI 180
+++WNG + ++ W+ + NMINGT G M+AP++ S L F + CRS+ TY S
Sbjct: 234 VDKWNGLSEVNYWHSEQCNMINGTAGQMWAPFMTPESSLEFFSPEACRSMKLTYQESRVF 293
Query: 181 KGVPSMNYAAPDSVFANHSVNPDNEGFCLDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYS 360
+G+P+ + APD++FAN SV P NEGFC C +G+ N+S C GAP+ +SQPHFY+
Sbjct: 294 EGIPTYRFTAPDTLFANGSVYPPNEGFC---PCRESGIQNVSTC-RFGAPLFLSQPHFYN 349
Query: 361 AAEKYIDAVYGINPS-SEFKTILKLEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNISSV 537
A +AV G+NP E L + P TG+P+ + K+Q+++ IK VK + I V
Sbjct: 350 ADPVLSEAVLGLNPDPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGVGQTGKIEPV 409
Query: 538 VLPMMWLNESVLISDALAGTIRSTLVL 618
VLP++W +S ++ T + LVL
Sbjct: 410 VLPLLWFEQSGMMGGKTLNTFYTQLVL 436
>sp|Q60417|SCRB1_CRIGR Scavenger receptor class B member 1 (SRB1) (SR-BI) (HaSR-BI)
Length = 509
Score = 164 bits (415), Expect = 3e-40
Identities = 83/207 (40%), Positives = 122/207 (58%), Gaps = 1/207 (0%)
Frame = +1
Query: 1 IERWNGSNHISMWNDKYANMINGTDGSMFAPYLNRSSRLYIFQSDICRSIYATYVGSEEI 180
++RWNG + ++ W+ + NMINGT G M+AP++ S L F + CRS+ TY S
Sbjct: 234 VDRWNGLSKVNYWHSEQCNMINGTSGQMWAPFMTPQSSLEFFSPEACRSMKLTYHDSGVF 293
Query: 181 KGVPSMNYAAPDSVFANHSVNPDNEGFCLDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYS 360
+G+P+ + AP ++FAN SV P NEGFC C+ +G+ N+S C GAP+ +S PHFY+
Sbjct: 294 EGIPTYRFTAPKTLFANGSVYPPNEGFC---PCLESGIQNVSTC-RFGAPLFLSHPHFYN 349
Query: 361 AAEKYIDAVYGINPS-SEFKTILKLEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNISSV 537
A +AV G+NP E L + P TG+P+ + KLQI++ IK VK + I V
Sbjct: 350 ADPVLSEAVLGLNPDpreHSLFLDIHPVTGIPMNCSVKLQISLYIKAVKGIGQTGKIEPV 409
Query: 538 VLPMMWLNESVLISDALAGTIRSTLVL 618
VLP++W +S + T + LVL
Sbjct: 410 VLPLLWFEQSGAMGGEPLNTFYTQLVL 436
>sp|Q61009|SCRB1_MOUSE Scavenger receptor class B member 1 (SRB1) (SR-BI)
Length = 509
Score = 164 bits (415), Expect = 3e-40
Identities = 82/207 (39%), Positives = 122/207 (58%), Gaps = 1/207 (0%)
Frame = +1
Query: 1 IERWNGSNHISMWNDKYANMINGTDGSMFAPYLNRSSRLYIFQSDICRSIYATYVGSEEI 180
+++WNG + I W+ + NMINGT G M+AP++ S L F + CRS+ TY S
Sbjct: 234 VDKWNGLSKIDYWHSEQCNMINGTSGQMWAPFMTPESSLEFFSPEACRSMKLTYNESRVF 293
Query: 181 KGVPSMNYAAPDSVFANHSVNPDNEGFCLDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYS 360
+G+P+ + APD++FAN SV P NEGFC C +G+ N+S C GAP+ +S PHFY+
Sbjct: 294 EGIPTYRFTAPDTLFANGSVYPPNEGFC---PCRESGIQNVSTC-RFGAPLFLSHPHFYN 349
Query: 361 AAEKYIDAVYGINPS-SEFKTILKLEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNISSV 537
A +AV G+NP+ E L + P TG+P+ + K+Q+++ IK VK + I V
Sbjct: 350 ADPVLSEAVLGLNPNPKEHSLFLDIHPVTGIPMNCSVKMQLSLYIKSVKGIGQTGKIEPV 409
Query: 538 VLPMMWLNESVLISDALAGTIRSTLVL 618
VLP++W +S + T + LVL
Sbjct: 410 VLPLLWFEQSGAMGGKPLSTFYTQLVL 436
>sp|P70110|CD36_MESAU Platelet glycoprotein IV (GPIV) (GPIIIB) (CD36 antigen) (PAS IV)
(PAS-4 protein)
Length = 472
Score = 159 bits (401), Expect = 1e-38
Identities = 82/208 (39%), Positives = 123/208 (59%), Gaps = 6/208 (2%)
Frame = +1
Query: 1 IERWNGSNHISMWNDKYANMINGTDGSMFAPYLNRSSRLYIFQSDICRSIYATYVGSEEI 180
I+ + G ++S W + Y +MINGTD + F P++ +S L F SDICRSIYA + E+
Sbjct: 227 IDSYKGKRNLSYW-ESYCDMINGTDAASFPPFVEKSRVLRFFSSDICRSIYAVFGSDIEL 285
Query: 181 KGVPSMNYAAPDSVFANHSVNPDNEGFC----LDGDCMGAGVLNLSKCVPGGAPIIMSQP 348
KG+P + P FA+ NPDN FC + +C GVL++SKC G P+ +S P
Sbjct: 286 KGIPVYRFILPAKAFASPVQNPDNHCFCTEKVISNNCTSYGVLDISKC-KQGRPVYISLP 344
Query: 349 HFYSAAEKYIDAVYGINPS-SEFKTILKLEPTTGLPLQLAKKLQINIAIKPVKDFFKMDN 525
HF A+ + + G+NP+ E +T L +EP TG LQ AK+LQ+NI +KP + + N
Sbjct: 345 HFLHASPDISEPIEGLNPNEEEHRTYLDVEPITGFTLQFAKRLQVNILVKPARKIEALKN 404
Query: 526 IS-SVVLPMMWLNESVLISDALAGTIRS 606
+ + ++P++WLNE+ I D A R+
Sbjct: 405 LKRNYIVPILWLNETGTIGDEKAEMFRN 432
>sp|Q8SQC1|SCRB1_PIG Scavenger receptor class B member 1 (SRB1) (SR-BI) (High density
lipoprotein receptor SR-BI)
Length = 509
Score = 157 bits (396), Expect = 4e-38
Identities = 78/207 (37%), Positives = 123/207 (59%), Gaps = 1/207 (0%)
Frame = +1
Query: 1 IERWNGSNHISMWNDKYANMINGTDGSMFAPYLNRSSRLYIFQSDICRSIYATYVGSEEI 180
+++WNG + ++ W+ NMINGT G M+AP++ S L + + CRS+ Y
Sbjct: 234 VDKWNGLSKVNFWHSDQCNMINGTSGQMWAPFMTPESSLEFYSPEACRSMKLIYKEQGVF 293
Query: 181 KGVPSMNYAAPDSVFANHSVNPDNEGFCLDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYS 360
+G+P+ + AP+++FAN SV P NEGFC CM +G+ N+S C AP+ +S PHFY+
Sbjct: 294 EGIPTFRFVAPNTLFANGSVYPPNEGFC---PCMESGIQNVSTC-RFNAPLFLSHPHFYN 349
Query: 361 AAEKYIDAVYGINPSSEFKTI-LKLEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNISSV 537
A +AV G++P++E ++ L + P TG+P+ + KLQ+++ IK VK + I V
Sbjct: 350 ADPVLAEAVSGLHPNTEEHSLFLDIHPVTGIPMNCSVKLQLSLYIKSVKGIGQTGKIEPV 409
Query: 538 VLPMMWLNESVLISDALAGTIRSTLVL 618
VLP++W ES + T + LVL
Sbjct: 410 VLPLLWFAESGAMEGETLQTFYTQLVL 436
>sp|P16671|CD36_HUMAN Platelet glycoprotein IV (GPIV) (Glycoprotein IIIb) (GPIIIB)
(Leukocyte differentiation antigen CD36) (CD36 antigen)
(PAS IV) (PAS-4 protein) (Platelet collagen receptor)
(Fatty acid translocase) (FAT) (Thrombospondin receptor)
Length = 472
Score = 155 bits (392), Expect = 1e-37
Identities = 80/208 (38%), Positives = 122/208 (58%), Gaps = 6/208 (2%)
Frame = +1
Query: 1 IERWNGSNHISMWNDKYANMINGTDGSMFAPYLNRSSRLYIFQSDICRSIYATYVGSEEI 180
I+ + G ++S W + + +MINGTD + F P++ +S L F SDICRSIYA + +
Sbjct: 227 IDTYKGKRNLSYW-ESHCDMINGTDAASFPPFVEKSQVLQFFSSDICRSIYAVFESDVNL 285
Query: 181 KGVPSMNYAAPDSVFANHSVNPDNEGFC----LDGDCMGAGVLNLSKCVPGGAPIIMSQP 348
KG+P + P FA+ NPDN FC + +C GVL++SKC G P+ +S P
Sbjct: 286 KGIPVYRFVLPSKAFASPVENPDNYCFCTEKIISKNCTSYGVLDISKC-KEGRPVYISLP 344
Query: 349 HFYSAAEKYIDAVYGINPS-SEFKTILKLEPTTGLPLQLAKKLQINIAIKPVKDFFKMDN 525
HF A+ + + G+NP+ E +T L +EP TG LQ AK+LQ+N+ +KP + + N
Sbjct: 345 HFLYASPDVSEPIDGLNPNEEEHRTYLDIEPITGFTLQFAKRLQVNLLVKPSEKIQVLKN 404
Query: 526 IS-SVVLPMMWLNESVLISDALAGTIRS 606
+ + ++P++WLNE+ I D A RS
Sbjct: 405 LKRNYIVPILWLNETGTIGDEKANMFRS 432
>sp|O18824|SCRB1_BOVIN Scavenger receptor class B member 1 (SRB1) (SR-BI)
Length = 509
Score = 155 bits (391), Expect = 2e-37
Identities = 78/207 (37%), Positives = 117/207 (56%), Gaps = 1/207 (0%)
Frame = +1
Query: 1 IERWNGSNHISMWNDKYANMINGTDGSMFAPYLNRSSRLYIFQSDICRSIYATYVGSEEI 180
+++WNG + ++ W+ NMINGT G M+AP++ S L + + CRS+ Y
Sbjct: 234 VDKWNGVSKVNYWHSDQCNMINGTSGQMWAPFMTPESSLEFYSPEACRSMKLVYKEQGVF 293
Query: 181 KGVPSMNYAAPDSVFANHSVNPDNEGFCLDGDCMGAGVLNLSKCVPGGAPIIMSQPHFYS 360
G+P+ + AP ++FAN SV P NEGFC C +G+ N+S C AP+ +S PHFY+
Sbjct: 294 GGIPTFRFVAPSTLFANGSVYPPNEGFC---PCRESGIQNVSTC-RFNAPLFLSHPHFYN 349
Query: 361 AAEKYIDAVYGINPS-SEFKTILKLEPTTGLPLQLAKKLQINIAIKPVKDFFKMDNISSV 537
A +AV G++P+ E L + P TG+P+ + KLQ+++ +K VK + NI V
Sbjct: 350 ADPVLAEAVSGLHPNPKEHSLFLDIHPVTGIPMNCSVKLQLSLFVKSVKGIGQTGNIQPV 409
Query: 538 VLPMMWLNESVLISDALAGTIRSTLVL 618
VLP+MW ES + T LVL
Sbjct: 410 VLPLMWFEESGAMEGETLETFYIQLVL 436
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,612,929
Number of Sequences: 369166
Number of extensions: 2309874
Number of successful extensions: 6911
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6532
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6848
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7357347200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)