Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_O20
(563 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9CR26|CF055_MOUSE Protein C6orf55 homolog 111 1e-24
sp|Q9NP79|CF055_HUMAN Protein C6orf55 (Dopamine-responsive ... 110 2e-24
sp|Q06263|VTA1_YEAST Vacuolar protein sorting-associated pr... 42 8e-04
sp|Q9BRQ0|PYGO2_HUMAN Pygopus homolog 2 41 0.002
sp|P10163|PR4S_HUMAN Basic salivary proline-rich protein 4 ... 39 0.012
sp|Q50634|SECD_MYCTU Protein-export membrane protein secD 39 0.012
sp|Q04118|PRB3_HUMAN Basic salivary proline-rich protein 3 ... 37 0.026
sp|P30595|CHS2_RHIOL Chitin synthase 2 (Chitin-UDP acetyl-g... 37 0.026
sp|P10162|PRB4L_HUMAN Basic salivary proline-rich protein 4... 37 0.044
sp|Q6PB44|PTN23_MOUSE Tyrosine-protein phosphatase, non-rec... 37 0.044
>sp|Q9CR26|CF055_MOUSE Protein C6orf55 homolog
Length = 309
Score = 111 bits (278), Expect = 1e-24
Identities = 71/190 (37%), Positives = 103/190 (54%), Gaps = 26/190 (13%)
Frame = +2
Query: 2 SGFLMDVLSVFGEVGEDIEKCRKYAKWKAVYINQCLKKGEIPHSGPI----DNDQEISDF 169
+ L+DV++VFGE+ ++ K RKYA+WKA YI+ CLK GE P +GP+ +ND E ++
Sbjct: 121 ASLLIDVITVFGELTDENVKHRKYARWKATYIHNCLKNGETPQAGPVGIEEENDVEENE- 179
Query: 170 NFPTVTQPTRPPQGSSNV---PSSTQPNPKPRTQKPVGG----------------VDNES 292
+ + PT+PPQ SS+ PS+ P Q P G N
Sbjct: 180 DVGATSLPTQPPQPSSSSAYDPSNLAPGSYSGIQIPPGAHAPANTPAEVPHSTGVTSNAV 239
Query: 293 KPINPTIASSYHPEPPPAAANS---HLTAEDFAHAEKLCKYAASALQYQDSPTALEYLTK 463
+P T+ ++ +P A+ LT EDFA A+K CKYA SALQY+D TA++ L K
Sbjct: 240 QPSPQTVPAAPAVDPDLYTASQGDIRLTPEDFARAQKYCKYAGSALQYEDVGTAVQNLQK 299
Query: 464 CVDLLKYGKK 493
+ LL G++
Sbjct: 300 ALRLLTTGRE 309
>sp|Q9NP79|CF055_HUMAN Protein C6orf55 (Dopamine-responsive protein DRG-1)
Length = 307
Score = 110 bits (276), Expect = 2e-24
Identities = 75/192 (39%), Positives = 100/192 (52%), Gaps = 28/192 (14%)
Frame = +2
Query: 2 SGFLMDVLSVFGEVGEDIEKCRKYAKWKAVYINQCLKKGEIPHSGPI----DND-QEISD 166
+ L+DV++VFGE+ ++ K RKYA+WKA YI+ CLK GE P +GP+ DND +E D
Sbjct: 121 ASLLIDVITVFGELTDENVKHRKYARWKATYIHNCLKNGETPQAGPVGIEEDNDIEENED 180
Query: 167 FNFPTV-TQPTRPPQGS----SNVPSS------------TQPNPKPRTQKPVGGVDNESK 295
++ TQPT+P S SN+PS N G N +
Sbjct: 181 AGAASLPTQPTQPSSSSTYDPSNMPSGNYTGIQIPPGAHAPANTPAEVPHSTGVASNTIQ 240
Query: 296 PINPTIASSYHPEPPPAAANS------HLTAEDFAHAEKLCKYAASALQYQDSPTALEYL 457
P TI P PA N+ LT EDFA A+K CKYA SALQY+D TA++ L
Sbjct: 241 PTPQTI-----PAIDPALFNTISQGDVRLTPEDFARAQKYCKYAGSALQYEDVSTAVQNL 295
Query: 458 TKCVDLLKYGKK 493
K + LL G++
Sbjct: 296 QKALKLLTTGRE 307
>sp|Q06263|VTA1_YEAST Vacuolar protein sorting-associated protein VTA1 (VPS20-associated
protein 1)
Length = 330
Score = 42.4 bits (98), Expect = 8e-04
Identities = 24/60 (40%), Positives = 31/60 (51%), Gaps = 10/60 (16%)
Frame = +2
Query: 329 PEPPPAAANSHLTAEDFA----------HAEKLCKYAASALQYQDSPTALEYLTKCVDLL 478
P P AA + T ++ +KL KYA SAL Y+D PTA + LTK +DLL
Sbjct: 268 PSEPAAAEHKSYTKDELTKIMDRASKIEQIQKLAKYAISALNYEDLPTAKDELTKALDLL 327
>sp|Q9BRQ0|PYGO2_HUMAN Pygopus homolog 2
Length = 406
Score = 40.8 bits (94), Expect = 0.002
Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Frame = +2
Query: 134 GPIDNDQEISDFNFPTVTQPT-RPPQGSSNVPSSTQPNPKPRTQKPVGGVDNESKPINPT 310
GP Q + P P RP QG ++P +T P P P P G ++ KP+NP
Sbjct: 207 GPPSLSQRFAQPGAPFGPSPLQRPGQGLPSLPPNTSPFPGPDPGFPGPGGEDGGKPLNPP 266
Query: 311 IASSYHPEP----PPAAANSH 361
++++ EP P AA N +
Sbjct: 267 ASTAFPQEPHSGSPAAAVNGN 287
>sp|P10163|PR4S_HUMAN Basic salivary proline-rich protein 4 allele S precursor (Salivary
proline-rich protein Po) (Parotid o protein) [Contains:
Protein N1; Glycosylated protein A]
Length = 247
Score = 38.5 bits (88), Expect = 0.012
Identities = 19/52 (36%), Positives = 23/52 (44%)
Frame = +2
Query: 188 QPTRPPQGSSNVPSSTQPNPKPRTQKPVGGVDNESKPINPTIASSYHPEPPP 343
+P PPQ N P P KP+ P GG N +P +P P PPP
Sbjct: 182 KPQGPPQQEGNKPQGPPPPGKPQGPPPAGG--NPQQPQDPPAGKPQGPPPPP 231
Score = 32.0 bits (71), Expect = 1.1
Identities = 28/92 (30%), Positives = 34/92 (36%), Gaps = 6/92 (6%)
Frame = +2
Query: 113 KGEIPHSG----PIDNDQEISDFNFPTVTQPTRPPQGSSNVPSSTQPNP-KPRTQKPVGG 277
+G PH G P S P +P RPP N P P KP P GG
Sbjct: 90 QGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGG 149
Query: 278 VDNESKPINPTIASSYHPE-PPPAAANSHLTA 370
++ P +P PE PPP N +A
Sbjct: 150 NQSQGPPPHPG-----KPEGPPPQEGNKSRSA 176
Score = 30.8 bits (68), Expect = 2.4
Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 1/53 (1%)
Frame = +2
Query: 200 PPQGSSNVPSSTQPNPKPRTQKPVGGVDNESKPINPTIASSYHPE-PPPAAAN 355
PPQG + P KP + P GG ++ P +P PE PPP N
Sbjct: 61 PPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPG-----KPERPPPQGGN 108
Score = 28.9 bits (63), Expect = 9.2
Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 10/59 (16%)
Frame = +2
Query: 197 RPPQGSSNVPSSTQPNP-KPRTQKPVGGVDNESKPINPTIA---------SSYHPEPPP 343
RPPQG N P+P KP P GG ++ P P S+ P PPP
Sbjct: 81 RPPQGG-NQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPP 138
>sp|Q50634|SECD_MYCTU Protein-export membrane protein secD
Length = 573
Score = 38.5 bits (88), Expect = 0.012
Identities = 40/144 (27%), Positives = 50/144 (34%), Gaps = 3/144 (2%)
Frame = +2
Query: 44 GEDIEKCRKYAKWKAVYINQCLKKGEIPHSGPIDNDQEISDFNFPTVTQPTRPPQGSSNV 223
G D + R + +YI L +P + Q QP PP S
Sbjct: 101 GNDGSEARNLGQTARLYIRPVLNS--MPAQPAAEEPQPAPSAEPQPPGQPAAPPPAQSGA 158
Query: 224 PSSTQPNPKPRTQKPVGGVDNESKPINPTIASSYHPEPP---PAAANSHLTAEDFAHAEK 394
P+S QP +PR D P NPT +S P PP PA AE A +K
Sbjct: 159 PASPQPGAQPRPYPQ----DPAPSP-NPTSPASPPPAPPAEAPATDPRKDLAERIAQEKK 213
Query: 395 LCKYAASALQYQDSPTALEYLTKC 466
L S QY T+C
Sbjct: 214 L---RQSTNQYMQMVALQFQATRC 234
>sp|Q04118|PRB3_HUMAN Basic salivary proline-rich protein 3 precursor (Parotid salivary
glycoprotein G1) (Proline-rich protein G1)
Length = 309
Score = 37.4 bits (85), Expect = 0.026
Identities = 19/62 (30%), Positives = 24/62 (38%)
Frame = +2
Query: 176 PTVTQPTRPPQGSSNVPSSTQPNPKPRTQKPVGGVDNESKPINPTIASSYHPEPPPAAAN 355
P +P PP N P P +P+ P GG N +P+ P P PPP
Sbjct: 241 PHPGKPQGPPPQEGNKPQRPPPPRRPQGPPPPGG--NPQQPLPPPAGKPQGPPPPPQGGR 298
Query: 356 SH 361
H
Sbjct: 299 PH 300
Score = 31.2 bits (69), Expect = 1.9
Identities = 21/62 (33%), Positives = 24/62 (38%), Gaps = 2/62 (3%)
Frame = +2
Query: 176 PTVTQPTRPPQGSSNVPSSTQPNP-KPRTQKPVGGVDNESKPINPTIASSYHPE-PPPAA 349
P +P PP N P P KP Q P GG ++ P P PE PPP
Sbjct: 52 PRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPG-----KPEGPPPQG 106
Query: 350 AN 355
N
Sbjct: 107 GN 108
Score = 29.6 bits (65), Expect = 5.4
Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 2/62 (3%)
Frame = +2
Query: 176 PTVTQPTRPPQGSSNVPSSTQPNP-KPRTQKPVGGVDNESKPINPTIASSYHPE-PPPAA 349
P +P PP N P+P KP P GG ++ P P PE PPP
Sbjct: 115 PRPGEPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPG-----KPEGPPPQG 169
Query: 350 AN 355
N
Sbjct: 170 GN 171
Score = 29.3 bits (64), Expect = 7.0
Identities = 26/87 (29%), Positives = 30/87 (34%), Gaps = 6/87 (6%)
Frame = +2
Query: 113 KGEIPH----SGPIDNDQEISDFNFPTVTQPTRPPQGSSNVPSSTQPNP-KPRTQKPVGG 277
+G PH GP S P +P PP N P P KP P GG
Sbjct: 132 QGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG 191
Query: 278 VDNESKPINPTIASSYHPE-PPPAAAN 355
++ P P PE PPP N
Sbjct: 192 NQSQGPPPRPG-----KPEGPPPQGGN 213
>sp|P30595|CHS2_RHIOL Chitin synthase 2 (Chitin-UDP acetyl-glucosaminyl transferase 2)
Length = 858
Score = 37.4 bits (85), Expect = 0.026
Identities = 20/72 (27%), Positives = 29/72 (40%)
Frame = +2
Query: 125 PHSGPIDNDQEISDFNFPTVTQPTRPPQGSSNVPSSTQPNPKPRTQKPVGGVDNESKPIN 304
P P DQ D P +T P PP P P Q+P +N P++
Sbjct: 30 PFEDPYPEDQPHFDKQ-PLLTSPAYPPTQYPTSPPPPNFPGSPAVQQPYPPFNNNPSPVS 88
Query: 305 PTIASSYHPEPP 340
P + + ++P PP
Sbjct: 89 PGVPAYFNPAPP 100
>sp|P10162|PRB4L_HUMAN Basic salivary proline-rich protein 4 allele L (Salivary
proline-rich protein Po) (Parotid o protein) [Contains:
Peptide P-D]
Length = 276
Score = 36.6 bits (83), Expect = 0.044
Identities = 19/52 (36%), Positives = 22/52 (42%)
Frame = +2
Query: 188 QPTRPPQGSSNVPSSTQPNPKPRTQKPVGGVDNESKPINPTIASSYHPEPPP 343
+P PPQ N P P KP+ P GG N +P P P PPP
Sbjct: 211 KPQGPPQQEGNKPQGPPPPGKPQGPPPPGG--NPQQPQAPPAGKPQGPPPPP 260
Score = 33.9 bits (76), Expect = 0.29
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 10/66 (15%)
Frame = +2
Query: 176 PTVTQPTRPPQGSSNVPSSTQPNP-KPRTQKPVGGVDNESKPINPTIA---------SSY 325
PT +P PP N T P P KP + P GG ++ P +P S+
Sbjct: 102 PTPGKPEGPPPQGGNQSQGTPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSH 161
Query: 326 HPEPPP 343
P PPP
Sbjct: 162 RPPPPP 167
Score = 33.5 bits (75), Expect = 0.37
Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 2/62 (3%)
Frame = +2
Query: 176 PTVTQPTRPPQGSSNVPSSTQPNP-KPRTQKPVGGVDNESKPINPTIASSYHPE-PPPAA 349
P +P RPP N P+P KP ++ P GG ++ P P PE PPP
Sbjct: 60 PHPGKPERPPPQGGNQSQGPPPHPGKPESRPPQGGHQSQGPPPTPG-----KPEGPPPQG 114
Query: 350 AN 355
N
Sbjct: 115 GN 116
Score = 30.8 bits (68), Expect = 2.4
Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 1/53 (1%)
Frame = +2
Query: 200 PPQGSSNVPSSTQPNPKPRTQKPVGGVDNESKPINPTIASSYHPE-PPPAAAN 355
PPQG + P KP + P GG ++ P +P PE PPP N
Sbjct: 27 PPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPG-----KPERPPPQGGN 74
Score = 30.8 bits (68), Expect = 2.4
Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 2/67 (2%)
Frame = +2
Query: 176 PTVTQPTRPPQGSSNVPSSTQPNP-KPRTQKPVGGVDNESKPINPTIASSYHPE-PPPAA 349
P +P RPP N P P KP P GG ++ P +P PE PPP
Sbjct: 144 PHPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPG-----KPEGPPPQE 198
Query: 350 ANSHLTA 370
N +A
Sbjct: 199 GNKSRSA 205
Score = 29.6 bits (65), Expect = 5.4
Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 8/57 (14%)
Frame = +2
Query: 197 RPPQGSSNVPSSTQPNP-KPRTQKPVGGVDNESKPINPTIASSYHPE-------PPP 343
RPPQG N P+P KP P GG ++ P +P S P+ PPP
Sbjct: 47 RPPQGG-NQSQGPPPHPGKPERPPPQGGNQSQGPPPHPGKPESRPPQGGHQSQGPPP 102
>sp|Q6PB44|PTN23_MOUSE Tyrosine-protein phosphatase, non-receptor type 23
Length = 1692
Score = 36.6 bits (83), Expect = 0.044
Identities = 25/89 (28%), Positives = 35/89 (39%), Gaps = 5/89 (5%)
Frame = +2
Query: 122 IPHSGPIDNDQEISDFNFPTVTQPTRPPQGSSNVPSSTQPNPKPRTQKPVGGVDNESKPI 301
+P +GP Q QP PQ S QP P+P+ Q+P G +P+
Sbjct: 972 VPRTGPQAQAQPQPQPQPQPQPQPQPQPQPQPQSQSQPQPQPQPQPQRPAFGPQPTQQPL 1031
Query: 302 ---NPTIASSYHPE--PPPAAANSHLTAE 373
+P + S P PPP H T +
Sbjct: 1032 PFQHPHLFPSQAPGILPPPPPTPYHFTPQ 1060
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,032,188
Number of Sequences: 369166
Number of extensions: 1339121
Number of successful extensions: 6925
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5367
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6524
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4078830820
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)