Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_O15
(414 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q969H0|FBXW7_HUMAN F-box/WD-repeat protein 7 (F-box and ... 114 6e-26
sp|Q9VZF4|FBXW7_DROME F-box/WD-repeat protein 7 (F-box and ... 114 6e-26
sp|Q8VBV4|FBXW7_MOUSE F-box/WD-repeat protein 7 (F-box and ... 112 2e-25
sp|Q93794|SEL10_CAEEL F-box/WD-repeat protein sel-10 (Suppr... 99 3e-21
sp|O14170|POP2_SCHPO WD-repeat protein pop2 (Proteolysis fa... 47 2e-05
sp|P53699|CDC4_CANAL Cell division control protein 4 47 2e-05
sp|Q8YRI1|YY46_ANASP Hypothetical WD-repeat protein alr3466 45 6e-05
sp|Q8YV57|Y2124_ANASP Hypothetical WD-repeat protein all2124 43 2e-04
sp|Q17963|YKY4_CAEEL Hypothetical WD-repeat protein C14B1.4... 43 3e-04
sp|Q9UKB1|FBW1B_HUMAN F-box/WD-repeat protein 11 (F-box/WD-... 42 4e-04
>sp|Q969H0|FBXW7_HUMAN F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7) (F-box
protein FBX30) (hCdc4) (Archipelago homolog) (hAgo)
(SEL-10)
Length = 707
Score = 114 bits (286), Expect = 6e-26
Identities = 54/108 (50%), Positives = 76/108 (70%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTF 181
NAD++V++W I TG+C+ L G N+H +A+T +Q + +++S+ DG+VKLW+L G F
Sbjct: 598 NADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKN-FVITSSDDGTVKLWDLKTGEF 656
Query: 182 IRDIVKLENASRGAVVWRSMNNNNHLVCAVGSRNDTERTKLIFFDFSV 325
IR++V LE+ G VVWR +N LVCAVGSRN TE TKL+ DF V
Sbjct: 657 IRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDV 704
Score = 41.2 bits (95), Expect = 8e-04
Identities = 21/62 (33%), Positives = 36/62 (58%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTFIR 187
DN+++VW TG+C+ L G H+ + S Q + D +I+S + D ++K+WN G I
Sbjct: 400 DNTLKVWSAVTGKCLRTLVG---HTGGVWSSQ-MRDNIIISGSTDRTLKVWNAETGECIH 455
Query: 188 DI 193
+
Sbjct: 456 TL 457
Score = 38.5 bits (88), Expect = 0.005
Identities = 16/58 (27%), Positives = 36/58 (62%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDG 175
+ D +++VW TGEC+ LYG H++ + + + ++ +VS + D ++++W++ G
Sbjct: 438 STDRTLKVWNAETGECIHTLYG---HTSTVRCMHL-HEKRVVSGSRDATLRVWDIETG 491
Score = 36.6 bits (83), Expect = 0.021
Identities = 23/52 (44%), Positives = 31/52 (59%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWN 163
D ++RVW I TG+C+ L G H AA+ VQ R +VS A D VK+W+
Sbjct: 480 DATLRVWDIETGQCLHVLMG---HVAAVRCVQYD-GRRVVSGAYDFMVKVWD 527
>sp|Q9VZF4|FBXW7_DROME F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7)
(Archipelago protein)
Length = 1326
Score = 114 bits (286), Expect = 6e-26
Identities = 54/109 (49%), Positives = 78/109 (71%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTF 181
NAD++V+VW I+TG+C+ L G N+H +A+T +Q R +V+S+ DG+VKLW++ G F
Sbjct: 1212 NADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFN-SRFVVTSSDDGTVKLWDVKTGDF 1270
Query: 182 IRDIVKLENASRGAVVWRSMNNNNHLVCAVGSRNDTERTKLIFFDFSVK 328
IR++V L++ G VVWR N+ L+CAVGSRN TE TKL+ DF V+
Sbjct: 1271 IRNLVALDSGGSGGVVWRIRANDTKLICAVGSRNGTEETKLMVLDFDVE 1319
Score = 36.6 bits (83), Expect = 0.021
Identities = 17/62 (27%), Positives = 36/62 (58%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTFIR 187
DN+++VW G+C+ L G H+ + S Q + +I+S + D ++K+W+++ G +
Sbjct: 1014 DNTLKVWSAVNGKCLRTLVG---HTGGVWSSQ-MSGNIIISGSTDRTLKVWDMDSGACVH 1069
Query: 188 DI 193
+
Sbjct: 1070 TL 1071
Score = 35.4 bits (80), Expect = 0.046
Identities = 23/52 (44%), Positives = 30/52 (57%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWN 163
D ++RVW I G C+ L G H AA+ VQ +LIVS A D VK+W+
Sbjct: 1094 DATLRVWDIEQGSCLHVLVG---HLAAVRCVQYD-GKLIVSGAYDYMVKIWH 1141
Score = 32.7 bits (73), Expect = 0.30
Identities = 15/65 (23%), Positives = 38/65 (58%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTF 181
+ D +++VW + +G CV L G H++ + + + + +VS + D ++++W++ G+
Sbjct: 1052 STDRTLKVWDMDSGACVHTLQG---HTSTVRCMHLHGSK-VVSGSRDATLRVWDIEQGSC 1107
Query: 182 IRDIV 196
+ +V
Sbjct: 1108 LHVLV 1112
>sp|Q8VBV4|FBXW7_MOUSE F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7) (F-box
protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat
protein 6) (SEL-10)
Length = 629
Score = 112 bits (281), Expect = 2e-25
Identities = 53/108 (49%), Positives = 76/108 (70%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTF 181
NAD++V++W I TG+C+ L G ++H +A+T +Q + +++S+ DG+VKLW+L G F
Sbjct: 520 NADSTVKIWDIKTGQCLQTLQGPSKHQSAVTCLQFNKN-FVITSSDDGTVKLWDLKTGEF 578
Query: 182 IRDIVKLENASRGAVVWRSMNNNNHLVCAVGSRNDTERTKLIFFDFSV 325
IR++V LE+ G VVWR +N LVCAVGSRN TE TKL+ DF V
Sbjct: 579 IRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDV 626
Score = 41.2 bits (95), Expect = 8e-04
Identities = 21/62 (33%), Positives = 36/62 (58%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTFIR 187
DN+++VW TG+C+ L G H+ + S Q + D +I+S + D ++K+WN G I
Sbjct: 322 DNTLKVWSAVTGKCLRTLVG---HTGGVWSSQ-MRDNIIISGSTDRTLKVWNAETGECIH 377
Query: 188 DI 193
+
Sbjct: 378 TL 379
Score = 38.5 bits (88), Expect = 0.005
Identities = 16/58 (27%), Positives = 36/58 (62%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDG 175
+ D +++VW TGEC+ LYG H++ + + + ++ +VS + D ++++W++ G
Sbjct: 360 STDRTLKVWNAETGECIHTLYG---HTSTVRCMHL-HEKRVVSGSRDATLRVWDIETG 413
Score = 36.6 bits (83), Expect = 0.021
Identities = 23/52 (44%), Positives = 31/52 (59%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWN 163
D ++RVW I TG+C+ L G H AA+ VQ R +VS A D VK+W+
Sbjct: 402 DATLRVWDIETGQCLHVLMG---HVAAVRCVQYD-GRRVVSGAYDFMVKVWD 449
>sp|Q93794|SEL10_CAEEL F-box/WD-repeat protein sel-10 (Suppressor/enhancer of lin-12)
(Sel-10 protein)
Length = 587
Score = 99.4 bits (246), Expect = 3e-21
Identities = 49/106 (46%), Positives = 68/106 (64%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTF 181
NAD+ VRVW I G CV L G H +A+TS+Q ++ +S+ DG+VKLW++ G
Sbjct: 480 NADSHVRVWDIHEGTCVHMLSG---HRSAITSLQWFGRNMVATSSDDGTVKLWDIERGAL 536
Query: 182 IRDIVKLENASRGAVVWRSMNNNNHLVCAVGSRNDTERTKLIFFDF 319
IRD+V L++ G +WR + + L CAVGSRN+TE TK+I DF
Sbjct: 537 IRDLVTLDSGGNGGCIWRLCSTSTMLACAVGSRNNTEETKVILLDF 582
Score = 39.7 bits (91), Expect = 0.002
Identities = 22/63 (34%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIV-LDRLIVSSAGDGSVKLWNLNDGTFI 184
DN+++VW I GE + L G H+ + + QI R IVS + D +VK+W+ DG+ +
Sbjct: 275 DNTLKVWCIDKGEVMYTLVG---HTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLL 331
Query: 185 RDI 193
+
Sbjct: 332 HTL 334
Score = 37.7 bits (86), Expect = 0.009
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTFIR 187
D ++RVW + +G + L+G H AA+ VQ +VS D +VK+WN + G IR
Sbjct: 357 DTTLRVWDVESGRHLATLHG---HHAAVRCVQFD-GTTVVSGGYDFTVKIWNAHTGRCIR 412
Query: 188 DIVKLEN 208
+ N
Sbjct: 413 TLTGHNN 419
>sp|O14170|POP2_SCHPO WD-repeat protein pop2 (Proteolysis factor sud1)
Length = 703
Score = 46.6 bits (109), Expect = 2e-05
Identities = 23/58 (39%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDR-LIVSSAGDGSVKLWNLNDGT 178
D+S+R+W +STGEC+ L G HS + SV +R + +S + D S+++W+L+ GT
Sbjct: 526 DSSIRIWRVSTGECLYHLRG---HSLRIYSVLYEPERNICISGSMDKSIRVWDLSTGT 580
Score = 45.8 bits (107), Expect = 3e-05
Identities = 24/56 (42%), Positives = 35/56 (62%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDG 175
D S+RVW +STG C L G H A +T + + +RLI SA D ++++W+LN G
Sbjct: 568 DKSIRVWDLSTGTCKYVLEG---HDAFVTLLNVFQNRLISGSA-DSTIRIWDLNTG 619
Score = 40.0 bits (92), Expect = 0.002
Identities = 19/62 (30%), Positives = 37/62 (59%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTF 181
+AD+++R+W ++TG+ ++ L + + ++ S D + S DGSVKLW++ G
Sbjct: 606 SADSTIRIWDLNTGKPLMVLPSNSGYISSFVS-----DEHKIISGNDGSVKLWDVRTGKL 660
Query: 182 IR 187
+R
Sbjct: 661 LR 662
>sp|P53699|CDC4_CANAL Cell division control protein 4
Length = 684
Score = 46.6 bits (109), Expect = 2e-05
Identities = 37/108 (34%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +2
Query: 5 ADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTFI 184
AD ++R+W TGE +L G H AA+T + D L V S + +KLWN+ GTF
Sbjct: 581 ADATLRIWDAKTGELRSKLKG---HGAAITCFEH--DGLRVVSGSEKMLKLWNVEKGTFA 635
Query: 185 RDIVKLENASRGAVVWRSMNNNNHLVCAVGS--RNDTERTKLIFFDFS 322
RD+ L + + G +W+ + V AV D T + DFS
Sbjct: 636 RDL--LSDVTGG--IWQVRFDYKRCVAAVQRIINEDEGETFIEILDFS 679
Score = 35.8 bits (81), Expect = 0.035
Identities = 17/56 (30%), Positives = 32/56 (57%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDG 175
D+++ VW TGE L G A+L + ++D ++VS+A D ++++W+ G
Sbjct: 542 DSNINVWNFETGELKKVLVGH----ASLVGLLDLVDDVLVSAAADATLRIWDAKTG 593
>sp|Q8YRI1|YY46_ANASP Hypothetical WD-repeat protein alr3466
Length = 1526
Score = 45.1 bits (105), Expect = 6e-05
Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDG-SVKLWNLNDGTFI 184
D +VR+W IS+GEC+ L+G H ++ SV D LI++S D ++KLW++ G I
Sbjct: 1431 DQTVRLWNISSGECLYTLHG---HINSVRSVAFSSDGLILASGSDDETIKLWDVKTGECI 1487
Query: 185 RDI 193
+ +
Sbjct: 1488 KTL 1490
Score = 42.7 bits (99), Expect = 3e-04
Identities = 27/96 (28%), Positives = 50/96 (52%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTF 181
+ D +VR+W IS+G+C+ L G N ++ V L+ S + D +V+LWN++ G
Sbjct: 1387 SGDQTVRLWSISSGKCLYTLQGHNNWVGSI--VFSPDGTLLASGSDDQTVRLWNISSGEC 1444
Query: 182 IRDIVKLENASRGAVVWRSMNNNNHLVCAVGSRNDT 289
+ + N+ R +++ L+ A GS ++T
Sbjct: 1445 LYTLHGHINSVRSVAF-----SSDGLILASGSDDET 1475
Score = 40.4 bits (93), Expect = 0.001
Identities = 21/57 (36%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGS-VKLWNLNDG 175
D +VR+W IS+G C+ L G H++ + SV D +++S GD V+LW+++ G
Sbjct: 1053 DQTVRLWDISSGNCLYTLQG---HTSCVRSVVFSPDGAMLASGGDDQIVRLWDISSG 1106
Score = 40.0 bits (92), Expect = 0.002
Identities = 21/57 (36%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLD-RLIVSSAGDGSVKLWNLNDG 175
D +VR+W IS+GEC+ G H+ + SV D ++ S +GD +V+LW+++ G
Sbjct: 1347 DQTVRLWSISSGECLYTFLG---HTNWVGSVIFSPDGAILASGSGDQTVRLWSISSG 1400
Score = 39.7 bits (91), Expect = 0.002
Identities = 21/57 (36%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLD-RLIVSSAGDGSVKLWNLN 169
++D +VR+W IS+GEC LY H+ + SV LD ++ + +GD +V+LW+++
Sbjct: 967 SSDQTVRLWDISSGEC---LYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDIS 1020
Score = 37.0 bits (84), Expect = 0.016
Identities = 19/57 (33%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSS-AGDGSVKLWNLNDG 175
D +VR+W IS+G+C+ G H++ + SV + L+++S + D +V+LW+++ G
Sbjct: 927 DQTVRLWDISSGQCLKTFKG---HTSRVRSVVFSPNSLMLASGSSDQTVRLWDISSG 980
Score = 33.9 bits (76), Expect = 0.13
Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLD-RLIVSSAGDGSVKLWNLN 169
++D +VR+W IS+ +C+ G H+ + SV D ++ S +GD +V+LW ++
Sbjct: 1261 SSDKTVRLWDISSSKCLHTFQG---HTNWVNSVAFNPDGSMLASGSGDQTVRLWEIS 1314
Score = 32.7 bits (73), Expect = 0.30
Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLD-RLIVSSAGDGSVKLWNLN 169
++D VR+W IS+ +C+ L G H+ + +V D + S +GD +V+LW+++
Sbjct: 1135 SSDQIVRLWDISSKKCLYTLQG---HTNWVNAVAFSPDGATLASGSGDQTVRLWDIS 1188
>sp|Q8YV57|Y2124_ANASP Hypothetical WD-repeat protein all2124
Length = 1683
Score = 43.1 bits (100), Expect = 2e-04
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLD-RLIVSSAGDGSVKLWNLNDGT 178
NAD +V++W + G+ + L G H + V D + + S++ D +VKLWN++DG
Sbjct: 1423 NADKTVKIWRVRDGKALKTLIG---HDNEVNKVNFSPDGKTLASASRDNTVKLWNVSDGK 1479
Query: 179 FIRDIVKLENASRGAVVWRSMNNNNHLVCAVGS 277
F + + V W S + + ++ + +
Sbjct: 1480 FKKTL----KGHTDEVFWVSFSPDGKIIASASA 1508
Score = 38.9 bits (89), Expect = 0.004
Identities = 19/65 (29%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLD-RLIVSSAGDGSVKLWNLNDGT 178
++D+S+++W ++G+ ++ L G HSA + +V+ D + I + + D +VKLW+ DG
Sbjct: 1174 SSDHSIKLWDTTSGQLLMTLTG---HSAGVITVRFSPDGQTIAAGSEDKTVKLWHRQDGK 1230
Query: 179 FIRDI 193
++ +
Sbjct: 1231 LLKTL 1235
Score = 37.0 bits (84), Expect = 0.016
Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 21/117 (17%)
Frame = +2
Query: 8 DNSVRVW---LISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAG-DGSVKLWNLNDG 175
DN++R+W LIS LE+ N + + +V + D I+++AG DG+++LW+ DG
Sbjct: 1343 DNTIRLWQRPLISP----LEVLAGN---SGVYAVSFLHDGSIIATAGADGNIQLWHSQDG 1395
Query: 176 TFIR-----------------DIVKLENASRGAVVWRSMNNNNHLVCAVGSRNDTER 295
+ ++ D++ NA + +WR + + L +G N+ +
Sbjct: 1396 SLLKTLPGNKAIYGISFTPQGDLIASANADKTVKIWR-VRDGKALKTLIGHDNEVNK 1451
Score = 34.7 bits (78), Expect = 0.078
Identities = 18/55 (32%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLD-RLIVSSAGDGSVKLWN 163
+AD ++++W I+ G+ V L G H+ ++ V D + I S++ D ++KLWN
Sbjct: 1258 SADKTIKLWRIADGKLVKTLKG---HNDSVWDVNFSSDGKAIASASRDNTIKLWN 1309
Score = 32.3 bits (72), Expect = 0.39
Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLD-RLIVSSAGDGSVKLWNLNDGTFI 184
D +V++W G+ + L G H + S+ D + + S++ D ++KLW + DG +
Sbjct: 1218 DKTVKLWHRQDGKLLKTLNG---HQDWVNSLSFSPDGKTLASASADKTIKLWRIADGKLV 1274
Query: 185 RDIVKLENASRGAVVWRSMNNNNHLVCAVGSRNDT 289
+ + K N S VW +++ A SR++T
Sbjct: 1275 KTL-KGHNDS----VWDVNFSSDGKAIASASRDNT 1304
Score = 32.0 bits (71), Expect = 0.51
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Frame = +2
Query: 71 NRHSAALTSVQIVLDRLIVSSAG-DGSVKLWNLNDGTFIRDI 193
N H A+ SV D ++S G D ++KLW +DGT ++ I
Sbjct: 1110 NGHEDAVYSVSFSPDGQTIASGGSDKTIKLWQTSDGTLLKTI 1151
Score = 30.8 bits (68), Expect = 1.1
Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Frame = +2
Query: 5 ADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLD-RLIVSSAGDGSVKLWNLNDGTF 181
+D ++++W S G + + G H + +V D + + S++ D S+KLW+ G
Sbjct: 1133 SDKTIKLWQTSDGTLLKTITG---HEQTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQL 1189
Query: 182 IRDIVKLENASRGAVVWRSMNNNNHLVCAVGSRNDT 289
++ L S G + R + + A GS + T
Sbjct: 1190 ---LMTLTGHSAGVITVRFSPDGQTI--AAGSEDKT 1220
Score = 30.8 bits (68), Expect = 1.1
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLD-RLIVSSAGDGSVKLWNLNDG 175
+AD ++R+W +G + L H+ + SV D ++ S++ D +VKLW +DG
Sbjct: 1507 SADKTIRLWDSFSGNLIKSLPA---HNDLVYSVNFNPDGSMLASTSADKTVKLWRSHDG 1562
Score = 30.0 bits (66), Expect = 1.9
Identities = 17/68 (25%), Positives = 32/68 (47%)
Frame = +2
Query: 5 ADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTFI 184
AD ++++W G + L G + Q LI S+ D +VK+W + DG +
Sbjct: 1383 ADGNIQLWHSQDGSLLKTLPGNKAIYGISFTPQ---GDLIASANADKTVKIWRVRDGKAL 1439
Query: 185 RDIVKLEN 208
+ ++ +N
Sbjct: 1440 KTLIGHDN 1447
>sp|Q17963|YKY4_CAEEL Hypothetical WD-repeat protein C14B1.4 in chromosome III
Length = 376
Score = 42.7 bits (99), Expect = 3e-04
Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLD-RLIVSSAGDGSVKLWNLNDGTFI 184
D SVR+W + TG C+ L HS +++V D LI S + DG V++W+ +G I
Sbjct: 192 DESVRIWDVKTGMCIKTL---PAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCI 248
Query: 185 RDIVKLEN 208
+ +V EN
Sbjct: 249 KTLVDDEN 256
Score = 32.7 bits (73), Expect = 0.30
Identities = 17/68 (25%), Positives = 32/68 (47%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTFIR 187
D VR+W + G+C+ L + A + I++S D ++KLW+ + G ++
Sbjct: 234 DGLVRIWDTANGQCIKTLVDDENPPVAFVKFS-PNGKYILASNLDSTLKLWDFSKGKTLK 292
Query: 188 DIVKLENA 211
EN+
Sbjct: 293 QYTGHENS 300
>sp|Q9UKB1|FBW1B_HUMAN F-box/WD-repeat protein 11 (F-box/WD-repeat protein 1B) (F-box and
WD-repeats protein beta-TrCP2)
Length = 542
Score = 42.4 bits (98), Expect = 4e-04
Identities = 22/62 (35%), Positives = 34/62 (54%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTF 181
+ D +++VW ST E V L G R A L DRL+VS + D +++LW++ G
Sbjct: 380 SGDRTIKVWSTSTCEFVRTLNGHKRGIACLQ----YRDRLVVSGSSDNTIRLWDIECGAC 435
Query: 182 IR 187
+R
Sbjct: 436 LR 437
Score = 39.3 bits (90), Expect = 0.003
Identities = 18/63 (28%), Positives = 40/63 (63%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTFIR 187
DNS+++W ++ EC+ L G H+ ++ +Q +R+IV+ + D +V++W++N G +
Sbjct: 259 DNSIKIWDKTSLECLKVLTG---HTGSVLCLQYD-ERVIVTGSSDSTVRVWDVNTGEVLN 314
Query: 188 DIV 196
++
Sbjct: 315 TLI 317
Score = 37.0 bits (84), Expect = 0.016
Identities = 19/55 (34%), Positives = 33/55 (60%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNL 166
++DN++R+W I G C+ L G H + ++ ++ IVS A DG +K+W+L
Sbjct: 420 SSDNTIRLWDIECGACLRVLEG---HEELVRCIRFD-NKRIVSGAYDGKIKVWDL 470
Score = 32.3 bits (72), Expect = 0.39
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +2
Query: 8 DNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTFIR 187
D S+ VW +++ + H AA+ V D+ IVS++GD ++K+W+ + F+R
Sbjct: 339 DRSIAVWDMASATDITLRRVLVGHRAAVNVVDFD-DKYIVSASGDRTIKVWSTSTCEFVR 397
Query: 188 DI 193
+
Sbjct: 398 TL 399
Score = 31.6 bits (70), Expect = 0.66
Identities = 18/61 (29%), Positives = 37/61 (60%)
Frame = +2
Query: 2 NADNSVRVWLISTGECVLELYGENRHSAALTSVQIVLDRLIVSSAGDGSVKLWNLNDGTF 181
++D++VRVW ++TGE + L H+ A+ ++ + L+V+ + D S+ +W++ T
Sbjct: 297 SSDSTVRVWDVNTGEVLNTLI---HHNEAVLHLRF-SNGLMVTCSKDRSIAVWDMASATD 352
Query: 182 I 184
I
Sbjct: 353 I 353
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,026,144
Number of Sequences: 369166
Number of extensions: 852434
Number of successful extensions: 2803
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2273
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2707
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 1902516170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)