Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_O10
(671 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q68Y62|CPT1A_HORSE Carnitine O-palmitoyltransferase I, m... 226 4e-59
sp|P97742|CPT1A_MOUSE Carnitine O-palmitoyltransferase I, m... 225 7e-59
sp|P50416|CPT1A_HUMAN Carnitine O-palmitoyltransferase I, m... 225 9e-59
sp|Q8HY46|CPT1B_PIG Carnitine O-palmitoyltransferase I, mit... 223 4e-58
sp|Q92523|CPT1B_HUMAN Carnitine O-palmitoyltransferase I, m... 222 6e-58
sp|P32198|CPT1A_RAT Carnitine O-palmitoyltransferase I, mit... 219 4e-57
sp|Q924X2|CPT1B_MOUSE Carnitine O-palmitoyltransferase I, m... 216 6e-56
sp|Q63704|CPT1B_RAT Carnitine O-palmitoyltransferase I, mit... 214 2e-55
sp|Q8TCG5|CPT1C_HUMAN Carnitine O-palmitoyltransferase I, m... 188 1e-47
sp|Q8BGD5|CPT1C_MOUSE Carnitine O-palmitoyltransferase I, m... 184 1e-46
>sp|Q68Y62|CPT1A_HORSE Carnitine O-palmitoyltransferase I, mitochondrial liver isoform (CPT
I) (CPTI-L) (Carnitine palmitoyltransferase 1A)
Length = 776
Score = 226 bits (576), Expect = 4e-59
Identities = 109/188 (57%), Positives = 141/188 (75%)
Frame = +3
Query: 9 YYRLYGKFCQTYESSMTRLFRDGRTETVRSCSAEVSEAILSIEDKNIPNTTKILHFRKAA 188
+Y+ GKFC TYE+SMTRLFR+GRTETVRSCS+E +L++ D K+ F+ A+
Sbjct: 578 HYKDMGKFCLTYEASMTRLFREGRTETVRSCSSESCNFVLAMVDPTQTVKQKLRLFKIAS 637
Query: 189 EHHQKLYREAMTGKGVDRHLFCMFVICKFLNIKSEFLEKALSEPWKLSTSQTPLGQTKQL 368
E HQ LYR AMTG G+DRHLFC++V+ K+L + S FL++ LSEPW+LSTSQTP Q +
Sbjct: 638 EKHQHLYRLAMTGSGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQTPQQQVELF 697
Query: 369 DLTRYPDFISAGGGFGPVADDGYGVSYIIAGEDRLFFHISSKFSCKETNSEKFAGSLLKS 548
DL R P+++S+GGGFGPVADDGYGVSYI+ GE+ + FHISSKFS ET+S +F L ++
Sbjct: 698 DLERNPEYVSSGGGFGPVADDGYGVSYILVGENLINFHISSKFSSPETDSHRFGKHLKQA 757
Query: 549 MTDIKDLF 572
M DI LF
Sbjct: 758 MNDIMALF 765
>sp|P97742|CPT1A_MOUSE Carnitine O-palmitoyltransferase I, mitochondrial liver isoform (CPT
I) (CPTI-L) (Carnitine palmitoyltransferase 1A)
Length = 773
Score = 225 bits (574), Expect = 7e-59
Identities = 108/188 (57%), Positives = 137/188 (72%)
Frame = +3
Query: 9 YYRLYGKFCQTYESSMTRLFRDGRTETVRSCSAEVSEAILSIEDKNIPNTTKILHFRKAA 188
+Y+ GKFC TYE+SMTRLFR+GRTETVRSC+ E +L++ D + F+ A
Sbjct: 578 HYKDMGKFCLTYEASMTRLFREGRTETVRSCTTESCNFVLAMMDPTTTAEQRFKLFKIAC 637
Query: 189 EHHQKLYREAMTGKGVDRHLFCMFVICKFLNIKSEFLEKALSEPWKLSTSQTPLGQTKQL 368
E HQ LYR AMTG G+DRHLFC++V+ K+L + S FL++ LSEPW+LSTSQTP Q +
Sbjct: 638 EKHQHLYRLAMTGAGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQTPQQQVELF 697
Query: 369 DLTRYPDFISAGGGFGPVADDGYGVSYIIAGEDRLFFHISSKFSCKETNSEKFAGSLLKS 548
D +YPD++S GGGFGPVADDGYGVSYII GE+ + FHISSKFS ET+S +F L ++
Sbjct: 698 DFEKYPDYVSCGGGFGPVADDGYGVSYIIVGENFIHFHISSKFSSPETDSHRFGKHLRQA 757
Query: 549 MTDIKDLF 572
M DI LF
Sbjct: 758 MMDIITLF 765
>sp|P50416|CPT1A_HUMAN Carnitine O-palmitoyltransferase I, mitochondrial liver isoform (CPT
I) (CPTI-L) (Carnitine palmitoyltransferase 1A)
Length = 773
Score = 225 bits (573), Expect = 9e-59
Identities = 106/188 (56%), Positives = 142/188 (75%)
Frame = +3
Query: 9 YYRLYGKFCQTYESSMTRLFRDGRTETVRSCSAEVSEAILSIEDKNIPNTTKILHFRKAA 188
+Y+ GKFC TYE+SMTRLFR+GRTETVRSC+ E + + ++ D ++ F+ A+
Sbjct: 578 HYKDMGKFCLTYEASMTRLFREGRTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLAS 637
Query: 189 EHHQKLYREAMTGKGVDRHLFCMFVICKFLNIKSEFLEKALSEPWKLSTSQTPLGQTKQL 368
E HQ +YR AMTG G+DRHLFC++V+ K+L ++S FL++ LSEPW+LSTSQTP Q +
Sbjct: 638 EKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELF 697
Query: 369 DLTRYPDFISAGGGFGPVADDGYGVSYIIAGEDRLFFHISSKFSCKETNSEKFAGSLLKS 548
DL P+++S+GGGFGPVADDGYGVSYI+ GE+ + FHISSKFSC ET+S +F L ++
Sbjct: 698 DLENNPEYVSSGGGFGPVADDGYGVSYILVGENLINFHISSKFSCPETDSHRFGRHLKEA 757
Query: 549 MTDIKDLF 572
MTDI LF
Sbjct: 758 MTDIITLF 765
>sp|Q8HY46|CPT1B_PIG Carnitine O-palmitoyltransferase I, mitochondrial muscle isoform (CPT
I) (CPTI-M) (Carnitine palmitoyltransferase 1B)
Length = 772
Score = 223 bits (568), Expect = 4e-58
Identities = 105/193 (54%), Positives = 143/193 (74%), Gaps = 1/193 (0%)
Frame = +3
Query: 9 YYRLYGKFCQTYESSMTRLFRDGRTETVRSCSAEVSEAILS-IEDKNIPNTTKILHFRKA 185
Y+R GKFC TYE+SMTR+FR+GRTETVRSC+ E + + + +E + + + L FRKA
Sbjct: 578 YFRDRGKFCLTYEASMTRMFREGRTETVRSCTRESTAFVQAMVEGRRVKADLQDL-FRKA 636
Query: 186 AEHHQKLYREAMTGKGVDRHLFCMFVICKFLNIKSEFLEKALSEPWKLSTSQTPLGQTKQ 365
A+ HQ +YR AMTG G+DRHLFC++V+ K+L + S FL + LSEPW+LSTSQ Q +
Sbjct: 637 AQKHQNMYRLAMTGAGIDRHLFCLYVVSKYLGVSSPFLAEVLSEPWRLSTSQIAQFQIRM 696
Query: 366 LDLTRYPDFISAGGGFGPVADDGYGVSYIIAGEDRLFFHISSKFSCKETNSEKFAGSLLK 545
D +YP+ + AGGGFGPVADDGYGVSY+IAGE+ +FFH+SSKFS ETN+++F + +
Sbjct: 697 FDPNKYPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHVSSKFSSSETNAQRFGNHIRQ 756
Query: 546 SMTDIKDLFMTEK 584
++ D+ DLF K
Sbjct: 757 ALLDLADLFQVPK 769
>sp|Q92523|CPT1B_HUMAN Carnitine O-palmitoyltransferase I, mitochondrial muscle isoform (CPT
I) (CPTI-M) (Carnitine palmitoyltransferase 1B)
(Carnitine palmitoyltransferase I like protein)
Length = 772
Score = 222 bits (566), Expect = 6e-58
Identities = 103/192 (53%), Positives = 142/192 (73%)
Frame = +3
Query: 9 YYRLYGKFCQTYESSMTRLFRDGRTETVRSCSAEVSEAILSIEDKNIPNTTKILHFRKAA 188
++R GKFC TYE+SMTR+FR+GRTETVRSC++E + + ++ + + F+KAA
Sbjct: 578 HFRDRGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAA 637
Query: 189 EHHQKLYREAMTGKGVDRHLFCMFVICKFLNIKSEFLEKALSEPWKLSTSQTPLGQTKQL 368
+ HQ +YR AMTG G+DRHLFC++++ K+L + S FL + LSEPW+LSTSQ P Q +
Sbjct: 638 KKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSEPWRLSTSQIPQSQIRMF 697
Query: 369 DLTRYPDFISAGGGFGPVADDGYGVSYIIAGEDRLFFHISSKFSCKETNSEKFAGSLLKS 548
D ++P+ + AGGGFGPVADDGYGVSY+IAGE+ +FFHISSKFS ETN+++F + K+
Sbjct: 698 DPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKA 757
Query: 549 MTDIKDLFMTEK 584
+ DI DLF K
Sbjct: 758 LLDIADLFQVPK 769
>sp|P32198|CPT1A_RAT Carnitine O-palmitoyltransferase I, mitochondrial liver isoform (CPT
I) (CPTI-L) (Carnitine palmitoyltransferase 1A)
Length = 773
Score = 219 bits (559), Expect = 4e-57
Identities = 106/188 (56%), Positives = 136/188 (72%)
Frame = +3
Query: 9 YYRLYGKFCQTYESSMTRLFRDGRTETVRSCSAEVSEAILSIEDKNIPNTTKILHFRKAA 188
+Y+ GKFC TYE+SMTRLFR+GRTETVRSC+ E + ++ D ++ F+ A
Sbjct: 578 HYKDMGKFCLTYEASMTRLFREGRTETVRSCTMESCNFVQAMMDPKSTAEQRLKLFKIAC 637
Query: 189 EHHQKLYREAMTGKGVDRHLFCMFVICKFLNIKSEFLEKALSEPWKLSTSQTPLGQTKQL 368
E HQ LYR AMTG G+DRHLFC++V+ K+L + S FL++ LSEPW+LSTSQTP Q +
Sbjct: 638 EKHQHLYRLAMTGAGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQTPQQQVELF 697
Query: 369 DLTRYPDFISAGGGFGPVADDGYGVSYIIAGEDRLFFHISSKFSCKETNSEKFAGSLLKS 548
D + PD++S GGGFGPVADDGYGVSYII GE+ + FHISSKFS ET+S +F L ++
Sbjct: 698 DFEKNPDYVSCGGGFGPVADDGYGVSYIIVGENFIHFHISSKFSSPETDSHRFGKHLRQA 757
Query: 549 MTDIKDLF 572
M DI LF
Sbjct: 758 MMDIITLF 765
>sp|Q924X2|CPT1B_MOUSE Carnitine O-palmitoyltransferase I, mitochondrial muscle isoform (CPT
I) (CPTI-M) (Carnitine palmitoyltransferase 1B)
Length = 772
Score = 216 bits (549), Expect = 6e-56
Identities = 102/192 (53%), Positives = 138/192 (71%)
Frame = +3
Query: 9 YYRLYGKFCQTYESSMTRLFRDGRTETVRSCSAEVSEAILSIEDKNIPNTTKILHFRKAA 188
++R GKFC TYE+SMTR+FR+GRTETVRSC+ E + + ++ + FRKA+
Sbjct: 578 HFRDKGKFCLTYEASMTRMFREGRTETVRSCTNESAAFVQAMMKGSHKKQDLQDLFRKAS 637
Query: 189 EHHQKLYREAMTGKGVDRHLFCMFVICKFLNIKSEFLEKALSEPWKLSTSQTPLGQTKQL 368
E HQ +YR AMTG G+DRHLFC++++ K+L + S FL + LSEPW LSTSQ P Q
Sbjct: 638 EKHQNMYRLAMTGAGIDRHLFCLYIVSKYLGVSSPFLAEVLSEPWSLSTSQIPQFQICMF 697
Query: 369 DLTRYPDFISAGGGFGPVADDGYGVSYIIAGEDRLFFHISSKFSCKETNSEKFAGSLLKS 548
D +YP+ + AGGGFGPVADDGYGVSY+IAGE+ +FFHISSK+S ETN+++F + ++
Sbjct: 698 DPKQYPNHLGAGGGFGPVADDGYGVSYMIAGENTMFFHISSKYSSSETNAQRFGNHIRQA 757
Query: 549 MTDIKDLFMTEK 584
+ DI +LF K
Sbjct: 758 LLDIAELFKISK 769
>sp|Q63704|CPT1B_RAT Carnitine O-palmitoyltransferase I, mitochondrial muscle isoform (CPT
I) (CPTI-M) (Carnitine palmitoyltransferase 1B)
(Carnitine palmitoyltransferase I-like protein)
Length = 772
Score = 214 bits (545), Expect = 2e-55
Identities = 101/192 (52%), Positives = 138/192 (71%)
Frame = +3
Query: 9 YYRLYGKFCQTYESSMTRLFRDGRTETVRSCSAEVSEAILSIEDKNIPNTTKILHFRKAA 188
++R GKFC TYE+SMTR+FR+GRTETVRSC++E + + ++ + FRKA+
Sbjct: 578 HFRDKGKFCLTYEASMTRMFREGRTETVRSCTSESTAFVRAMMTGSHKKQDLQDLFRKAS 637
Query: 189 EHHQKLYREAMTGKGVDRHLFCMFVICKFLNIKSEFLEKALSEPWKLSTSQTPLGQTKQL 368
E HQ +YR AMTG G+DRHLFC++++ K+L ++S FL++ LSEPW LSTSQ P Q
Sbjct: 638 EKHQNMYRLAMTGAGIDRHLFCLYIVSKYLGVRSPFLDEVLSEPWSLSTSQIPQFQICMF 697
Query: 369 DLTRYPDFISAGGGFGPVADDGYGVSYIIAGEDRLFFHISSKFSCKETNSEKFAGSLLKS 548
D +YP+ + AGGGFGPVAD GYGVSY+IAGE+ +FFH+SSK S ETN+ +F + ++
Sbjct: 698 DPKQYPNHLGAGGGFGPVADHGYGVSYMIAGENTMFFHVSSKLSSSETNALRFGNHIRQA 757
Query: 549 MTDIKDLFMTEK 584
+ DI DLF K
Sbjct: 758 LLDIADLFKISK 769
>sp|Q8TCG5|CPT1C_HUMAN Carnitine O-palmitoyltransferase I, mitochondrial brain isoform
(Carnitine palmitoyltransferase 1C) (CPT IC)
Length = 803
Score = 188 bits (477), Expect = 1e-47
Identities = 89/188 (47%), Positives = 128/188 (68%)
Frame = +3
Query: 9 YYRLYGKFCQTYESSMTRLFRDGRTETVRSCSAEVSEAILSIEDKNIPNTTKILHFRKAA 188
++R G+FC TYES+MTRLF +GRTETVRSC+ E + ++EDK + + FR A
Sbjct: 575 HFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACNFVRAMEDKEKTDPQCLALFRVAV 634
Query: 189 EHHQKLYREAMTGKGVDRHLFCMFVICKFLNIKSEFLEKALSEPWKLSTSQTPLGQTKQL 368
+ HQ L + AM+G+GVDRHLF ++++ +FL+++S FL + SE W+LSTSQ P+ Q
Sbjct: 635 DKHQALLKAAMSGQGVDRHLFALYIVSRFLHLQSPFLTQVHSEQWQLSTSQIPVQQMHLF 694
Query: 369 DLTRYPDFISAGGGFGPVADDGYGVSYIIAGEDRLFFHISSKFSCKETNSEKFAGSLLKS 548
D+ YPD++S+GGGFGP D GYGVSYI G+ + FHISSK S +T+S + + +
Sbjct: 695 DVHNYPDYVSSGGGFGPADDHGYGVSYIFMGDGMITFHISSKKSSTKTDSHRLGQHIEDA 754
Query: 549 MTDIKDLF 572
+ D+ LF
Sbjct: 755 LLDVASLF 762
>sp|Q8BGD5|CPT1C_MOUSE Carnitine O-palmitoyltransferase I, mitochondrial brain isoform
(Carnitine palmitoyltransferase 1C) (CPT IC)
Length = 798
Score = 184 bits (468), Expect = 1e-46
Identities = 87/188 (46%), Positives = 129/188 (68%)
Frame = +3
Query: 9 YYRLYGKFCQTYESSMTRLFRDGRTETVRSCSAEVSEAILSIEDKNIPNTTKILHFRKAA 188
++R G+FC TYES+MTRLF +GRTETVRSC+ E + + ++++K L FR A
Sbjct: 574 HFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACQFVRAMDNKETDQHCLAL-FRVAV 632
Query: 189 EHHQKLYREAMTGKGVDRHLFCMFVICKFLNIKSEFLEKALSEPWKLSTSQTPLGQTKQL 368
+ HQ L + AM+G+G+DRHLF ++++ + L+++S FL + S+ W LSTSQ P+ QT +
Sbjct: 633 DKHQALLKAAMSGQGIDRHLFALYIMSRLLHMQSPFLTQVQSQQWLLSTSQVPVQQTHLI 692
Query: 369 DLTRYPDFISAGGGFGPVADDGYGVSYIIAGEDRLFFHISSKFSCKETNSEKFAGSLLKS 548
D+ YPD++S+GGGFGP D GYG+SYI GE+ + FHISSK S ET+S + + +
Sbjct: 693 DVHNYPDYVSSGGGFGPAHDHGYGISYIFMGENAITFHISSKKSSTETDSHRLGQHIENA 752
Query: 549 MTDIKDLF 572
+ D+ LF
Sbjct: 753 LLDVASLF 760
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,880,447
Number of Sequences: 369166
Number of extensions: 1543699
Number of successful extensions: 4163
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3961
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4121
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5636246860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)