Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_N11
(567 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P41570|6PGD_CERCA 6-phosphogluconate dehydrogenase, deca... 229 3e-60
sp|P41572|6PGD_DROME 6-phosphogluconate dehydrogenase, deca... 223 2e-58
sp|P41573|6PGD_DROSI 6-phosphogluconate dehydrogenase, deca... 223 2e-58
sp|O60037|6PGD_CUNEL 6-phosphogluconate dehydrogenase, deca... 222 6e-58
sp|Q9DCD0|6PGD_MOUSE 6-phosphogluconate dehydrogenase, deca... 218 6e-57
sp|P52209|6PGD_HUMAN 6-phosphogluconate dehydrogenase, deca... 218 8e-57
sp|P00349|6PGD_SHEEP 6-phosphogluconate dehydrogenase, deca... 218 1e-56
sp|Q17761|6PGD_CAEEL 6-phosphogluconate dehydrogenase, deca... 216 4e-56
sp|P14332|6PGD_PIG 6-phosphogluconate dehydrogenase, decarb... 210 2e-54
sp|P53319|6PGD2_YEAST 6-phosphogluconate dehydrogenase, dec... 197 2e-50
>sp|P41570|6PGD_CERCA 6-phosphogluconate dehydrogenase, decarboxylating
Length = 481
Score = 229 bits (585), Expect = 3e-60
Identities = 114/169 (67%), Positives = 128/169 (75%)
Frame = +2
Query: 14 DKTKFLNQIKYALYASKIISYTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQ 193
D KFLN IK+ALY SKI+SY QGFM+M+ A+ E WNL+ G IALMWRGGCIIRS FL
Sbjct: 313 DLPKFLNHIKHALYCSKIVSYAQGFMLMREAAKENNWNLNYGGIALMWRGGCIIRSVFLG 372
Query: 194 NIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLR 373
NIKDAY +N LS LL D FF+ I Q SWR VVANA L GIP PA S AL+FYDG R
Sbjct: 373 NIKDAYTRNPQLSNLLLDDFFKKAIEVGQNSWRQVVANAFLWGIPVPALSTALSFYDGYR 432
Query: 374 TEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAAASTYQA 520
TEKLPANL+QAQRD FGAH Y+LL G + HT+WTG GGN +ASTYQA
Sbjct: 433 TEKLPANLLQAQRDYFGAHTYELLGAEGKFVHTNWTGTGGNVSASTYQA 481
>sp|P41572|6PGD_DROME 6-phosphogluconate dehydrogenase, decarboxylating
Length = 481
Score = 223 bits (569), Expect = 2e-58
Identities = 109/167 (65%), Positives = 126/167 (75%)
Frame = +2
Query: 20 TKFLNQIKYALYASKIISYTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNI 199
TKFL+ IK+ALY +KI+SY QGFM+M+ A+ E KW L+ G IALMWRGGCIIRS FL NI
Sbjct: 315 TKFLDDIKHALYCAKIVSYAQGFMLMREAARENKWRLNYGGIALMWRGGCIIRSVFLGNI 374
Query: 200 KDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTE 379
KDAY LS LL D FF+ I + Q+SWR VVANA GIP PA S AL+FYDG RT
Sbjct: 375 KDAYTSQPELSNLLLDDFFKKAIERGQDSWREVVANAFRWGIPVPALSTALSFYDGYRTA 434
Query: 380 KLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAAASTYQA 520
KLPANL+QAQRD FGAH Y+LL G + HT+WTG GGN +ASTYQA
Sbjct: 435 KLPANLLQAQRDYFGAHTYELLGQEGQFHHTNWTGTGGNVSASTYQA 481
>sp|P41573|6PGD_DROSI 6-phosphogluconate dehydrogenase, decarboxylating
Length = 481
Score = 223 bits (569), Expect = 2e-58
Identities = 109/167 (65%), Positives = 126/167 (75%)
Frame = +2
Query: 20 TKFLNQIKYALYASKIISYTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQNI 199
TKFL+ IK+ALY +KI+SY QGFM+M+ A+ E KW L+ G IALMWRGGCIIRS FL NI
Sbjct: 315 TKFLDDIKHALYCAKIVSYAQGFMLMREAARENKWRLNYGGIALMWRGGCIIRSVFLGNI 374
Query: 200 KDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLRTE 379
KDAY LS LL D FF+ I + Q+SWR VVANA GIP PA S AL+FYDG RT
Sbjct: 375 KDAYTSQPQLSNLLLDDFFKKAIERGQDSWREVVANAFRWGIPVPALSTALSFYDGYRTA 434
Query: 380 KLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAAASTYQA 520
KLPANL+QAQRD FGAH Y+LL G + HT+WTG GGN +ASTYQA
Sbjct: 435 KLPANLLQAQRDYFGAHTYELLGQEGQFHHTNWTGTGGNVSASTYQA 481
>sp|O60037|6PGD_CUNEL 6-phosphogluconate dehydrogenase, decarboxylating
Length = 485
Score = 222 bits (565), Expect = 6e-58
Identities = 106/172 (61%), Positives = 128/172 (74%)
Frame = +2
Query: 5 FTGDKTKFLNQIKYALYASKIISYTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSR 184
FTGDK F+ Q+ ALYA+KI+SY QG+M+M+ A+ +++W L+ IALMWRGGCIIRS
Sbjct: 314 FTGDKKTFIAQLGQALYAAKIVSYAQGYMLMRQAAKDYEWKLNNAGIALMWRGGCIIRSV 373
Query: 185 FLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYD 364
FL I+DAY KN L LLFD FF+ K Q++WR+V A A L GIPTPA S AL FYD
Sbjct: 374 FLGKIRDAYTKNPELENLLFDDFFKDATAKAQDAWRNVTAQAVLMGIPTPALSTALNFYD 433
Query: 365 GLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAAASTYQA 520
GLR E LPANL+QAQRD FGAH Y+LL PG + HT+WTG GGN +ASTY A
Sbjct: 434 GLRHEILPANLLQAQRDYFGAHTYELLHTPGKWVHTNWTGRGGNVSASTYDA 485
>sp|Q9DCD0|6PGD_MOUSE 6-phosphogluconate dehydrogenase, decarboxylating
Length = 483
Score = 218 bits (556), Expect = 6e-57
Identities = 103/170 (60%), Positives = 125/170 (73%)
Frame = +2
Query: 11 GDKTKFLNQIKYALYASKIISYTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFL 190
G K FL I+ ALYASKIISY QGFM+++ A+ EF W L+ G IALMWRGGCIIRS FL
Sbjct: 314 GSKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFL 373
Query: 191 QNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGL 370
IKDA+E+N L LL D FF+S + CQ+SWR V++ GIP P F+ AL+FYDG
Sbjct: 374 GKIKDAFERNPELQNLLLDDFFKSAVDNCQDSWRRVISTGVQAGIPMPCFTTALSFYDGY 433
Query: 371 RTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAAASTYQA 520
R E LPANLIQAQRD FGAH Y+LL PG + HT+WTGHGG+ ++S+Y A
Sbjct: 434 RHEMLPANLIQAQRDYFGAHTYELLTKPGEFIHTNWTGHGGSVSSSSYNA 483
>sp|P52209|6PGD_HUMAN 6-phosphogluconate dehydrogenase, decarboxylating
Length = 483
Score = 218 bits (555), Expect = 8e-57
Identities = 103/172 (59%), Positives = 125/172 (72%)
Frame = +2
Query: 5 FTGDKTKFLNQIKYALYASKIISYTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSR 184
F GDK FL I+ ALYASKIISY QGFM+++ A+ EF W L+ G IALMWRGGCIIRS
Sbjct: 312 FDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSV 371
Query: 185 FLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYD 364
FL IKDA+++N L LL D FF+S + CQ+SWR V+ GIP P F+ AL+FYD
Sbjct: 372 FLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYD 431
Query: 365 GLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAAASTYQA 520
G R E LPA+LIQAQRD FGAH Y+LL PG + HT+WTGHGG ++S+Y A
Sbjct: 432 GYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNA 483
>sp|P00349|6PGD_SHEEP 6-phosphogluconate dehydrogenase, decarboxylating
Length = 483
Score = 218 bits (554), Expect = 1e-56
Identities = 102/172 (59%), Positives = 125/172 (72%)
Frame = +2
Query: 5 FTGDKTKFLNQIKYALYASKIISYTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSR 184
F GDK FL I+ ALYASKIISY QGFM+++ A+ EF W L+ G IALMWRGGCIIRS
Sbjct: 312 FEGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSV 371
Query: 185 FLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYD 364
FL IKDA+++N L LL D FF+S + CQ+SWR ++ GIP P F+ AL+FYD
Sbjct: 372 FLGKIKDAFDRNPGLQNLLLDDFFKSAVENCQDSWRRAISTGVQAGIPMPCFTTALSFYD 431
Query: 365 GLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAAASTYQA 520
G R LPANLIQAQRD FGAH Y+LL PG + HT+WTGHGG+ ++S+Y A
Sbjct: 432 GYRHAMLPANLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGSVSSSSYNA 483
>sp|Q17761|6PGD_CAEEL 6-phosphogluconate dehydrogenase, decarboxylating
Length = 484
Score = 216 bits (549), Expect = 4e-56
Identities = 104/169 (61%), Positives = 124/169 (73%)
Frame = +2
Query: 14 DKTKFLNQIKYALYASKIISYTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQ 193
DK F+ QI ALYASKI+SY QGFM++ AS +F WNL+ G IALMWRGGCIIRSRFL
Sbjct: 316 DKRVFIKQISKALYASKIVSYAQGFMLLAEASKQFNWNLNFGAIALMWRGGCIIRSRFLG 375
Query: 194 NIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLR 373
+I+ A++KNK LS LL D FF I + Q+SWR VV A GIP PAFS ALAFYDG
Sbjct: 376 DIEHAFQKNKQLSNLLLDDFFTKAITEAQDSWRVVVCAAVRLGIPVPAFSSALAFYDGYT 435
Query: 374 TEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAAASTYQA 520
+E +PANL+QAQRD FGAH Y+LL PGT+ HT+WTG GG ++ Y A
Sbjct: 436 SEVVPANLLQAQRDYFGAHTYELLAKPGTWVHTNWTGTGGRVTSNAYNA 484
>sp|P14332|6PGD_PIG 6-phosphogluconate dehydrogenase, decarboxylating
Length = 250
Score = 210 bits (534), Expect = 2e-54
Identities = 101/172 (58%), Positives = 125/172 (72%)
Frame = +2
Query: 5 FTGDKTKFLNQIKYALYASKIISYTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSR 184
F+GDK FL I+ ALYASKIISYTQGFM+++ A+ EF W+ + LMWRGGCIIRS
Sbjct: 80 FSGDKKSFLEDIRKALYASKIISYTQGFMLLRQAAAEFGWS-STTEHRLMWRGGCIIRSV 138
Query: 185 FLQNIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYD 364
FL IKDA+++N L LL D FF+S + CQ+SWR V+ GIP P F+ AL+FYD
Sbjct: 139 FLGKIKDAFDRNPGLQNLLLDDFFKSAVEDCQDSWRRAVSTGVQTGIPMPCFTTALSFYD 198
Query: 365 GLRTEKLPANLIQAQRDLFGAHQYQLLDHPGTYEHTDWTGHGGNAAASTYQA 520
G R E LPANLIQAQRD FGAH Y+LL PG + HT+WTGHGG+ ++S+Y A
Sbjct: 199 GYRHEMLPANLIQAQRDYFGAHTYELLAKPGHFVHTNWTGHGGSVSSSSYNA 250
>sp|P53319|6PGD2_YEAST 6-phosphogluconate dehydrogenase, decarboxylating 2
Length = 492
Score = 197 bits (501), Expect = 2e-50
Identities = 96/176 (54%), Positives = 124/176 (70%), Gaps = 7/176 (3%)
Frame = +2
Query: 14 DKTKFLNQIKYALYASKIISYTQGFMMMKSASHEFKWNLDLGKIALMWRGGCIIRSRFLQ 193
D+ +F+ ++ ALYASKIISY QGFM+++ A+ + W L+ IALMWRGGCIIRS FL
Sbjct: 317 DREQFVYDLEQALYASKIISYAQGFMLIREAARSYGWKLNNPAIALMWRGGCIIRSVFLA 376
Query: 194 NIKDAYEKNKNLSILLFDKFFQSEILKCQESWRHVVANAALHGIPTPAFSCALAFYDGLR 373
I AY + +L LLF++FF S + K Q WR +A AA +GIPTPAFS ALAFYDG R
Sbjct: 377 EITKAYRDDPDLENLLFNEFFASAVTKAQSGWRRTIALAATYGIPTPAFSTALAFYDGYR 436
Query: 374 TEKLPANLIQAQRDLFGAHQYQLLDHPGTYE-------HTDWTGHGGNAAASTYQA 520
+E+LPANL+QAQRD FGAH +++L + H +WTGHGGN ++STYQA
Sbjct: 437 SERLPANLLQAQRDYFGAHTFRILPECASAHLPVDKDIHINWTGHGGNISSSTYQA 492
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,543,368
Number of Sequences: 369166
Number of extensions: 1415362
Number of successful extensions: 3517
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3421
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3496
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4127973360
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)