Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_022_N04 (547 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8T6A5|TBA1_APLCA Tubulin alpha-1 chain 304 8e-83 sp|P05214|TBA3_MOUSE Tubulin alpha-3/alpha-7 chain (Alpha-t... 301 5e-82 sp|P18258|TBA1_PARLI Tubulin alpha-1 chain 301 7e-82 sp|Q94572|TBA3_HOMAM Tubulin alpha-3 chain (Alpha-III tubulin) 301 9e-82 sp|P09645|TBA8_CHICK Tubulin alpha-8 chain 300 2e-81 sp|P36220|TBA_TORMA Tubulin alpha chain (Alpha T6) 299 3e-81 sp|P68369|TBA1_MOUSE Tubulin alpha-1 chain (Alpha-tubulin 1... 299 3e-81 sp|P68361|TBA1_CRIGR Tubulin alpha-1 chain (Alpha-tubulin 1... 299 3e-81 sp|P02552|TBA1_CHICK Tubulin alpha-1 chain 299 3e-81 sp|Q25008|TBA1_HOMAM Tubulin alpha-1 chain (Alpha-I tubulin) 299 3e-81
>sp|Q8T6A5|TBA1_APLCA Tubulin alpha-1 chain Length = 451 Score = 304 bits (779), Expect = 8e-83 Identities = 144/180 (80%), Positives = 156/180 (86%) Frame = +3 Query: 3 YAPVVSAEKAYHEQLSVPEITTACFDPNNQMVKCDPRNGKYMACCMLYRGDVVPKDVNXX 182 YAPV+SAEKAYHEQLSV EIT ACF+P NQ+VKCDPR+GKYMACCMLYRGDVVPKDVN Sbjct: 272 YAPVISAEKAYHEQLSVAEITNACFEPANQLVKCDPRHGKYMACCMLYRGDVVPKDVNAA 331 Query: 183 XXXXXXXXXXQFVDWCPTGFKVGINYQPPTVVPGGDLAQVRRALCMLSNTTAISEAFTRL 362 QFVDWCPTGFKVGINYQPPTVVPGGDLA+V+RA+CMLSNTTAI+EA+ RL Sbjct: 332 IATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 391 Query: 363 NVKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGYDSADVANADQDDEY 542 + KFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVG DS D D+ +EY Sbjct: 392 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVDAEGEDEGEEY 451
>sp|P05214|TBA3_MOUSE Tubulin alpha-3/alpha-7 chain (Alpha-tubulin 3/7) (Alpha-tubulin isotype M-alpha-3/7) sp|Q68FR8|TBA3_RAT Tubulin alpha-3 chain (Alpha-tubulin 3) sp|Q13748|TBA2_HUMAN Tubulin alpha-2 chain (Alpha-tubulin 2) Length = 450 Score = 301 bits (772), Expect = 5e-82 Identities = 145/180 (80%), Positives = 158/180 (87%) Frame = +3 Query: 3 YAPVVSAEKAYHEQLSVPEITTACFDPNNQMVKCDPRNGKYMACCMLYRGDVVPKDVNXX 182 YAPV+SAEKAYHEQLSV EIT ACF+P NQMVKCDPR+GKYMACCMLYRGDVVPKDVN Sbjct: 272 YAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAA 331 Query: 183 XXXXXXXXXXQFVDWCPTGFKVGINYQPPTVVPGGDLAQVRRALCMLSNTTAISEAFTRL 362 QFVDWCPTGFKVGINYQPPTVVPGGDLA+V+RA+CMLSNTTAI+EA+ RL Sbjct: 332 IATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 391 Query: 363 NVKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGYDSADVANADQDDEY 542 + KFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVG DS + A A++ +EY Sbjct: 392 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVE-AEAEEGEEY 450
>sp|P18258|TBA1_PARLI Tubulin alpha-1 chain Length = 452 Score = 301 bits (771), Expect = 7e-82 Identities = 144/181 (79%), Positives = 158/181 (87%), Gaps = 1/181 (0%) Frame = +3 Query: 3 YAPVVSAEKAYHEQLSVPEITTACFDPNNQMVKCDPRNGKYMACCMLYRGDVVPKDVNXX 182 YAPV+SAEKAYHEQL+V EIT ACF+P NQMVKCDPR+GKYMACC+LYRGDVVPKDVN Sbjct: 272 YAPVISAEKAYHEQLTVSEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAA 331 Query: 183 XXXXXXXXXXQFVDWCPTGFKVGINYQPPTVVPGGDLAQVRRALCMLSNTTAISEAFTRL 362 QFVDWCPTGFKVGINYQPPTVVPGGDLA+V+RA+CMLSNTTAI+EA+ RL Sbjct: 332 IATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 391 Query: 363 NVKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGYDSADVANADQD-DE 539 + KFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVG DSAD +++ DE Sbjct: 392 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSADAEGEEEEGDE 451 Query: 540 Y 542 Y Sbjct: 452 Y 452
>sp|Q94572|TBA3_HOMAM Tubulin alpha-3 chain (Alpha-III tubulin) Length = 451 Score = 301 bits (770), Expect = 9e-82 Identities = 142/180 (78%), Positives = 155/180 (86%) Frame = +3 Query: 3 YAPVVSAEKAYHEQLSVPEITTACFDPNNQMVKCDPRNGKYMACCMLYRGDVVPKDVNXX 182 YAPV+SAEKAYHEQLSV EIT ACF+P NQMVKCDPR+GKYMACC+LYRGDVVPKDVN Sbjct: 272 YAPVISAEKAYHEQLSVSEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAA 331 Query: 183 XXXXXXXXXXQFVDWCPTGFKVGINYQPPTVVPGGDLAQVRRALCMLSNTTAISEAFTRL 362 QFVDWCPTGFKVGINYQPPT VPGGDLA+V RA+CMLSNTTAI+EA+ RL Sbjct: 332 IATIKTKRSIQFVDWCPTGFKVGINYQPPTAVPGGDLAKVSRAVCMLSNTTAIAEAWARL 391 Query: 363 NVKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGYDSADVANADQDDEY 542 + KFDLMYAKRAFVHWYVGEGMEEGEF+EAREDLAALEKDYEEVG DSAD ++ +EY Sbjct: 392 DHKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALEKDYEEVGVDSADAEGEEEGEEY 451
>sp|P09645|TBA8_CHICK Tubulin alpha-8 chain Length = 324 Score = 300 bits (767), Expect = 2e-81 Identities = 143/180 (79%), Positives = 157/180 (87%) Frame = +3 Query: 3 YAPVVSAEKAYHEQLSVPEITTACFDPNNQMVKCDPRNGKYMACCMLYRGDVVPKDVNXX 182 Y+P++SAEKAYHEQLSV EIT ACF+P+NQMVKCDPR+GKYMACCMLYRGDVVPKDVN Sbjct: 147 YSPIISAEKAYHEQLSVSEITNACFEPSNQMVKCDPRHGKYMACCMLYRGDVVPKDVNAA 206 Query: 183 XXXXXXXXXXQFVDWCPTGFKVGINYQPPTVVPGGDLAQVRRALCMLSNTTAISEAFTRL 362 QFVDWCPTGFKVGINYQPPTVVPGGDLA+V+RA+CMLSNTTAI+EA+ RL Sbjct: 207 IAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 266 Query: 363 NVKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGYDSADVANADQDDEY 542 + KFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVG DS D D+ +EY Sbjct: 267 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSMD--GEDEGEEY 324
>sp|P36220|TBA_TORMA Tubulin alpha chain (Alpha T6) Length = 451 Score = 299 bits (766), Expect = 3e-81 Identities = 141/180 (78%), Positives = 156/180 (86%) Frame = +3 Query: 3 YAPVVSAEKAYHEQLSVPEITTACFDPNNQMVKCDPRNGKYMACCMLYRGDVVPKDVNXX 182 YAPV+SAEKAYHEQLSV EIT ACF+P NQMVKCDPR+GKYMACC+LYRGDVVPKDVN Sbjct: 272 YAPVISAEKAYHEQLSVSEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAA 331 Query: 183 XXXXXXXXXXQFVDWCPTGFKVGINYQPPTVVPGGDLAQVRRALCMLSNTTAISEAFTRL 362 QFVDWCPTGFKVGINYQPPTVVPGGDLA+V+RA+CMLSNTTAI+EA+ RL Sbjct: 332 IATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 391 Query: 363 NVKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGYDSADVANADQDDEY 542 + KFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDYEEVG DS + ++ +EY Sbjct: 392 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY 451
>sp|P68369|TBA1_MOUSE Tubulin alpha-1 chain (Alpha-tubulin 1) (Alpha-tubulin isotype M-alpha-1) sp|P68362|TBA2_CRIGR Tubulin alpha-2 chain (Alpha-tubulin 2) (Alpha-tubulin II) sp|Q71U36|TBA3_HUMAN Tubulin alpha-3 chain (Alpha-tubulin 3) (Tubulin B-alpha-1) sp|P68370|TBA1_RAT Tubulin alpha-1 chain (Alpha-tubulin 1) Length = 451 Score = 299 bits (766), Expect = 3e-81 Identities = 141/180 (78%), Positives = 156/180 (86%) Frame = +3 Query: 3 YAPVVSAEKAYHEQLSVPEITTACFDPNNQMVKCDPRNGKYMACCMLYRGDVVPKDVNXX 182 YAPV+SAEKAYHEQLSV EIT ACF+P NQMVKCDPR+GKYMACC+LYRGDVVPKDVN Sbjct: 272 YAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAA 331 Query: 183 XXXXXXXXXXQFVDWCPTGFKVGINYQPPTVVPGGDLAQVRRALCMLSNTTAISEAFTRL 362 QFVDWCPTGFKVGINYQPPTVVPGGDLA+V+RA+CMLSNTTAI+EA+ RL Sbjct: 332 IATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 391 Query: 363 NVKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGYDSADVANADQDDEY 542 + KFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDYEEVG DS + ++ +EY Sbjct: 392 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY 451
>sp|P68361|TBA1_CRIGR Tubulin alpha-1 chain (Alpha-tubulin 1) (Alpha-tubulin I) sp|P68363|TBAK_HUMAN Tubulin alpha-ubiquitous chain (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) sp|P05213|TBA2_MOUSE Tubulin alpha-2 chain (Alpha-tubulin 2) (Alpha-tubulin isotype M-alpha-2) sp|P68360|TBA1_MERUN Tubulin alpha-1 chain (Alpha-tubulin 1) sp|Q6P9V9|TBA2_RAT Tubulin alpha-2 chain (Alpha-tubulin 2) Length = 451 Score = 299 bits (766), Expect = 3e-81 Identities = 141/180 (78%), Positives = 156/180 (86%) Frame = +3 Query: 3 YAPVVSAEKAYHEQLSVPEITTACFDPNNQMVKCDPRNGKYMACCMLYRGDVVPKDVNXX 182 YAPV+SAEKAYHEQLSV EIT ACF+P NQMVKCDPR+GKYMACC+LYRGDVVPKDVN Sbjct: 272 YAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAA 331 Query: 183 XXXXXXXXXXQFVDWCPTGFKVGINYQPPTVVPGGDLAQVRRALCMLSNTTAISEAFTRL 362 QFVDWCPTGFKVGINYQPPTVVPGGDLA+V+RA+CMLSNTTAI+EA+ RL Sbjct: 332 IATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 391 Query: 363 NVKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGYDSADVANADQDDEY 542 + KFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDYEEVG DS + ++ +EY Sbjct: 392 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY 451
>sp|P02552|TBA1_CHICK Tubulin alpha-1 chain Length = 412 Score = 299 bits (766), Expect = 3e-81 Identities = 141/180 (78%), Positives = 156/180 (86%) Frame = +3 Query: 3 YAPVVSAEKAYHEQLSVPEITTACFDPNNQMVKCDPRNGKYMACCMLYRGDVVPKDVNXX 182 YAPV+SAEKAYHEQLSV EIT ACF+P NQMVKCDPR+GKYMACC+LYRGDVVPKDVN Sbjct: 233 YAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAA 292 Query: 183 XXXXXXXXXXQFVDWCPTGFKVGINYQPPTVVPGGDLAQVRRALCMLSNTTAISEAFTRL 362 QFVDWCPTGFKVGINYQPPTVVPGGDLA+V+RA+CMLSNTTAI+EA+ RL Sbjct: 293 IATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 352 Query: 363 NVKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGYDSADVANADQDDEY 542 + KFDLMYAKRAFVHWYVGEGMEEGEFSEARED+AALEKDYEEVG DS + ++ +EY Sbjct: 353 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY 412
>sp|Q25008|TBA1_HOMAM Tubulin alpha-1 chain (Alpha-I tubulin) Length = 451 Score = 299 bits (766), Expect = 3e-81 Identities = 143/180 (79%), Positives = 155/180 (86%) Frame = +3 Query: 3 YAPVVSAEKAYHEQLSVPEITTACFDPNNQMVKCDPRNGKYMACCMLYRGDVVPKDVNXX 182 YAPV+SAEKAYHEQLSV EIT ACF+P NQMVKCDPR+GKYMACC+LYRGDVVPKDVN Sbjct: 272 YAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAA 331 Query: 183 XXXXXXXXXXQFVDWCPTGFKVGINYQPPTVVPGGDLAQVRRALCMLSNTTAISEAFTRL 362 QFVDWCPTGFKVGINYQPPTVVPG DLA+V RA+CMLSNTTAI+EA+ RL Sbjct: 332 IANIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGADLAKVSRAVCMLSNTTAIAEAWARL 391 Query: 363 NVKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGYDSADVANADQDDEY 542 + KFDLMYAKRAFVHWYVGEGMEEGEF+EAREDLAALEKDYEEVG DSAD + + DEY Sbjct: 392 DHKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALEKDYEEVGMDSADGEDIEGGDEY 451
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 60,545,872 Number of Sequences: 369166 Number of extensions: 1178411 Number of successful extensions: 3712 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3446 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3525 length of database: 68,354,980 effective HSP length: 104 effective length of database: 49,142,540 effective search space used: 3783975580 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)