Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_N02
(745 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8DHW6|SYC_SYNEL Cysteinyl-tRNA synthetase (Cysteine--tR... 35 0.28
sp|Q99N50|SYTL2_MOUSE Synaptotagmin-like protein 2 (Exophil... 34 0.47
sp|Q00400|DTH1_DUGTI Homeobox protein DTH-1 33 0.62
sp|P51816|AFF2_HUMAN AF4/FMR2 family member 2 (Fragile X me... 33 0.80
sp|P60810|PRSA2_LACJO Foldase protein prsA 2 precursor 33 1.1
sp|Q9HCH5|SYTL2_HUMAN Synaptotagmin-like protein 2 (Exophil... 33 1.1
sp|Q96YR5|RAD50_SULTO DNA double-strand break repair rad50 ... 33 1.1
sp|P48563|YN37_YEAST Hypothetical 186.8 kDa protein in CLA4... 32 1.4
sp|P10845|BXA1_CLOBO Botulinum neurotoxin type A precursor ... 32 1.4
sp|P47027|DPB11_YEAST DNA replication regulator DPB11 32 1.8
>sp|Q8DHW6|SYC_SYNEL Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase) (CysRS)
Length = 486
Score = 34.7 bits (78), Expect = 0.28
Identities = 28/126 (22%), Positives = 52/126 (41%)
Frame = +2
Query: 188 DSMSLNIPKVNSVDLQKFDFENESFQVAVNERSTIDLSSSMHANLPKPPSEAVEINDRPY 367
D M+L + + + + DF E+ A T+ + +H +P PP +A E+ P
Sbjct: 294 DPMALRLLVLQAQYRKPLDFTPEALTAAAKGWQTLGEALHLHQQIPLPPIDAAEVRSHP- 352
Query: 368 DSIVSLGEKYQKNDKFFSEELLDAVKKDNITHLQHLLSEERNLWLYFSNEKRFNIKISAD 547
K + + E+L A I L L+ E++ +L+ R ++S D
Sbjct: 353 --------KTEAFCQAMDEDLNTAAALAVIFELAKTLNREQHRYLHGGGWGRSPAEVSRD 404
Query: 548 AADLIS 565
L++
Sbjct: 405 WHTLVT 410
>sp|Q99N50|SYTL2_MOUSE Synaptotagmin-like protein 2 (Exophilin-4)
Length = 950
Score = 33.9 bits (76), Expect = 0.47
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Frame = +2
Query: 431 LDAVKKDNITHLQHLLSEERNL------WLYFSNEKRFNIKISADAADLI--SQRRLNAG 586
L +++ + HL + +++ L W Y + KR KI AD+I S RR
Sbjct: 25 LKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHG--ADIIRASMRRKKLP 82
Query: 587 IALEYQYDIMKQVTEYWLNNI 649
A E D + E W+NN+
Sbjct: 83 AAAEQNKDTAMRAKESWVNNV 103
>sp|Q00400|DTH1_DUGTI Homeobox protein DTH-1
Length = 533
Score = 33.5 bits (75), Expect = 0.62
Identities = 50/205 (24%), Positives = 81/205 (39%), Gaps = 19/205 (9%)
Frame = +2
Query: 23 NYKLFNVCIKTLSNAKFFNTSVYIYTNRILYRSNILKGTDKNNSEDSNEIINLSNDSMSL 202
+YKL IKT+SN + + L RS N D I NL
Sbjct: 264 SYKLSLPEIKTISNDWIKGSQNVNFNQNQLLRST--------NVSDYTLIKNLPQ----- 310
Query: 203 NIPKVNSVDLQKFDFENESFQVAVNERSTI---DLSSSMHANLPKPPSEAVEINDRPYDS 373
N+P N D NE+ Q N S + S +H N + +VE ND S
Sbjct: 311 NLPNPNQTDSIYSSSINENNQPIRNYDSPNPDREDDSEIHENPNPHDTSSVENNDNENSS 370
Query: 374 IVSLGEKYQKNDKFFSEELLD------------AVKKDNITHLQHLLSEERNLWLYFSNE 517
+G+K ++ F +++L+ A +++++ +L L + +W F N
Sbjct: 371 SGDIGKKRKRRVLFSKKQILELERHFRQKKYLSAPEREHLANLIGLSPTQVKIW--FQNH 428
Query: 518 ----KRFNIKISADAADLISQRRLN 580
KR + + + + +L RRLN
Sbjct: 429 RYKMKRAHHEKALEMGNLAVNRRLN 453
>sp|P51816|AFF2_HUMAN AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein)
(Protein FMR-2) (FMR2P) (Ox19 protein) (Fragile X E
mental retardation syndrome protein)
Length = 1311
Score = 33.1 bits (74), Expect = 0.80
Identities = 26/87 (29%), Positives = 37/87 (42%)
Frame = +2
Query: 95 YTNRILYRSNILKGTDKNNSEDSNEIINLSNDSMSLNIPKVNSVDLQKFDFENESFQVAV 274
YTN+ +N ++ T N E N + N SN + + IPK NSV + SF
Sbjct: 60 YTNKGDALANRVQNTLGNYDEMKNLLTNHSNQNHLVGIPK-NSVPQNPNNKNEPSFFPEQ 118
Query: 275 NERSTIDLSSSMHANLPKPPSEAVEIN 355
R + H + P PP V +N
Sbjct: 119 KNRIIPPHQDNTHPSAPMPPPSVVILN 145
>sp|P60810|PRSA2_LACJO Foldase protein prsA 2 precursor
Length = 298
Score = 32.7 bits (73), Expect = 1.1
Identities = 38/136 (27%), Positives = 56/136 (41%), Gaps = 12/136 (8%)
Frame = +2
Query: 170 IINLSNDSMSLNIPKVNSVDLQKFDFENESFQVAVNERSTIDLSSSMHANLPKPPSEAVE 349
I S D+ + I K+N+ ESF ++ S L+SS LP A +
Sbjct: 149 ISTTSRDTANTVIEKLNN---------GESFASLASKYSVDSLTSSNGGKLP-----AFD 194
Query: 350 INDRPYDSIVSLGEKYQKNDKFFSE-----------ELLDAVKKDNITHLQHLLSEE-RN 493
+ +R YDS G KND++ E ++++ KK N Q L+E N
Sbjct: 195 MQNRRYDSTFKKGAYKLKNDEYTKEPIKVTNGYEVIKMINHPKKGNFADKQKELTEAIYN 254
Query: 494 LWLYFSNEKRFNIKIS 541
W SN + N IS
Sbjct: 255 KWA--SNSRIMNNVIS 268
>sp|Q9HCH5|SYTL2_HUMAN Synaptotagmin-like protein 2 (Exophilin-4)
Length = 895
Score = 32.7 bits (73), Expect = 1.1
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Frame = +2
Query: 431 LDAVKKDNITHLQHLLSEERNL------WLYFSNEKRFNIKISADAADLI--SQRRLNAG 586
L +++ + HL + +++ L W Y + KR KI AD+I S R+
Sbjct: 10 LKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHG--ADIIRASMRKKRPQ 67
Query: 587 IALEYQYDIMKQVTEYWLNNI 649
IA E D E W+NN+
Sbjct: 68 IAAEQSKDRENGAKESWVNNV 88
>sp|Q96YR5|RAD50_SULTO DNA double-strand break repair rad50 ATPase
Length = 879
Score = 32.7 bits (73), Expect = 1.1
Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
Frame = +2
Query: 125 ILKGTDKNNSEDSNEIINLSNDSMSLNIPKVNSVDLQKFDFENESFQVAVNERSTIDLSS 304
ILK DSN I D ++ I ++ S++ K + EN+ Q E+ ++
Sbjct: 156 ILKIDKIEKLRDSNGPIKEVMDKINNKIIELQSLEKYKNESENQKIQ---KEKELENIKR 212
Query: 305 SMHANLPKPPSEAVEINDRPYDSIVSLGEKYQKNDKFFSE--ELLDAVKKDNITHLQHLL 478
+ K E + Y+ IV L E+ +K +K + E LL+ + KD+I+ L+ +
Sbjct: 213 ELEDLNIKEEKER-----KKYEDIVKLNEEEEKKEKRYVELISLLNKL-KDDISELREEV 266
Query: 479 SEERNL 496
+E L
Sbjct: 267 KDENRL 272
>sp|P48563|YN37_YEAST Hypothetical 186.8 kDa protein in CLA4-PUS4 intergenic region
Length = 1636
Score = 32.3 bits (72), Expect = 1.4
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 8/82 (9%)
Frame = +2
Query: 47 IKTLSNAKFFNTSVYIYTNRILYRSNILKGTDK--NNSEDSNEI------INLSNDSMSL 202
IK +SN + N S+ +YT R+ + I K T++ N+ E N++ NL DS+
Sbjct: 773 IKLISNREMDNDSLRLYTVRV-FTDIIKKATNEVGNSDEQDNKVKQFGTLENLVIDSLMA 831
Query: 203 NIPKVNSVDLQKFDFENESFQV 268
I + +D+ K + N + V
Sbjct: 832 TINSIKQLDIGKQEIYNGTINV 853
>sp|P10845|BXA1_CLOBO Botulinum neurotoxin type A precursor (BoNT/A) (Bontoxilysin A)
(BOTOX) [Contains: Botulinum neurotoxin A light-chain;
Botulinum neurotoxin A heavy-chain]
Length = 1296
Score = 32.3 bits (72), Expect = 1.4
Identities = 37/124 (29%), Positives = 58/124 (46%), Gaps = 9/124 (7%)
Frame = +2
Query: 53 TLSNAKFFNTSVYIYTNRIL-----YRSNILKGTDKNNSEDSNEIINLSNDSMSLNI-PK 214
TLS F S Y+ R+L Y NI+ + N +SN +I+LS + +NI K
Sbjct: 844 TLSTDIPFQLSKYVDNQRLLSTFTEYIKNIINTSILNLRYESNHLIDLSRYASKINIGSK 903
Query: 215 VNSVDLQKFD---FENESFQVAVNERSTIDLSSSMHANLPKPPSEAVEINDRPYDSIVSL 385
VN + K F ES ++ V ++ I + +SM+ N S + I Y + +SL
Sbjct: 904 VNFDPIDKNQIQLFNLESSKIEVILKNAI-VYNSMYENF----STSFWIRIPKYFNSISL 958
Query: 386 GEKY 397
+Y
Sbjct: 959 NNEY 962
>sp|P47027|DPB11_YEAST DNA replication regulator DPB11
Length = 764
Score = 32.0 bits (71), Expect = 1.8
Identities = 35/167 (20%), Positives = 73/167 (43%), Gaps = 5/167 (2%)
Frame = +2
Query: 92 IYTNRILYRSNILKGTDKNNSEDSNEIINLSNDSMSLNIPKVNSVDLQKFDFENESFQVA 271
++T + +N G + +N I+ S I K +S+ + F + A
Sbjct: 510 LFTQFCINNNNDDPGDNNRKDFQNNSILRNSMKRKIEYIKKFHSIPVVTPAFIFKLLSAA 569
Query: 272 VNERSTIDLSSSMHANL-PKPPSEAVEIN-DRPYDSIVSLGEKYQKNDKFFSEELLDAVK 445
E + I L++ + P+ + + +PY + +S +KYQ ND + +L +K
Sbjct: 570 SGENNEIFLNNIKWCIICPRGHKDDFKCKIKKPYYTSISSEKKYQNNDPKIDKTIL--LK 627
Query: 446 KDNITHLQHLLSEERNLWLYFSNEK---RFNIKISADAADLISQRRL 577
++N + +H + + +N L E R +S+ D+ S+R++
Sbjct: 628 RNNSSLSEHSMKDTKNELLQKIRETDSGRKKRSVSSSIMDVSSERQM 674
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,542,450
Number of Sequences: 369166
Number of extensions: 1078138
Number of successful extensions: 3466
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3333
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3463
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6728100400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)