Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_M08
(743 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9GP32|ALF_ECHMU Fructose-bisphosphate aldolase 323 3e-88
sp|P53442|ALF_SCHMA Fructose-bisphosphate aldolase 322 7e-88
sp|P53448|ALDOC_CARAU Fructose-bisphosphate aldolase C (Bra... 276 5e-74
sp|P00883|ALDOA_RABIT Fructose-bisphosphate aldolase A (Mus... 274 2e-73
sp|P05064|ALDOA_MOUSE Fructose-bisphosphate aldolase A (Mus... 274 2e-73
sp|P05065|ALDOA_RAT Fructose-bisphosphate aldolase A (Muscl... 274 2e-73
sp|P53445|ALF1_LAMJA Fructose-bisphosphate aldolase, muscle... 273 4e-73
sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A (Mus... 273 5e-73
sp|P07764|ALF_DROME Fructose-bisphosphate aldolase 272 8e-73
sp|P46563|ALF2_CAEEL Fructose-bisphosphate aldolase 2 (Aldo... 271 1e-72
>sp|Q9GP32|ALF_ECHMU Fructose-bisphosphate aldolase
Length = 363
Score = 323 bits (828), Expect = 3e-88
Identities = 161/204 (78%), Positives = 178/204 (87%)
Frame = +1
Query: 19 SHQAMLENANVLARYASICQQNAIVPIVEPEVLPDGNHSLEEAQKVTEEVLSYVYKALAD 198
S+ AMLENANVLARYA ICQQN +VPIVEPEVLPDG+H LE AQ+VTE+VLS+VYKALAD
Sbjct: 160 SYLAMLENANVLARYAFICQQNGLVPIVEPEVLPDGDHDLETAQRVTEQVLSFVYKALAD 219
Query: 199 HHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPAVAGVTFLSGGQSESD 378
HHVYLEGTLLKPNMVT GQSCT KY++E NA ATV+ALQRTVP AV GV FLSGGQSE D
Sbjct: 220 HHVYLEGTLLKPNMVTCGQSCTKKYSVEDNARATVEALQRTVPVAVPGVVFLSGGQSELD 279
Query: 379 ATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAAQDQLLHLASANGAAA 558
AT NLNAINKY G+KPW L+FSFGRALQAS + AW+GK ENVKA Q + L LA ANGAA+
Sbjct: 280 ATRNLNAINKYPGKKPWALSFSFGRALQASAIAAWQGKPENVKAGQAEFLQLAKANGAAS 339
Query: 559 VGKFDGNLKTAAGGKSLFVANHAY 630
+GKF+G LKTAAG KSLFVANHAY
Sbjct: 340 LGKFEGELKTAAGQKSLFVANHAY 363
>sp|P53442|ALF_SCHMA Fructose-bisphosphate aldolase
Length = 363
Score = 322 bits (825), Expect = 7e-88
Identities = 162/206 (78%), Positives = 178/206 (86%)
Frame = +1
Query: 13 TRSHQAMLENANVLARYASICQQNAIVPIVEPEVLPDGNHSLEEAQKVTEEVLSYVYKAL 192
T S+ AMLENANVLARYASICQQN +VPIVEPEVLPDG+H L AQ+VTE+VL++VYKAL
Sbjct: 158 TPSYLAMLENANVLARYASICQQNGLVPIVEPEVLPDGDHDLLTAQRVTEQVLAFVYKAL 217
Query: 193 ADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPAVAGVTFLSGGQSE 372
ADHHVYLEGTLLKPNMVTAGQ+C YT ++NA ATV+ALQRTVPPAV G+TFLSGGQSE
Sbjct: 218 ADHHVYLEGTLLKPNMVTAGQACKKAYTPQENALATVRALQRTVPPAVPGITFLSGGQSE 277
Query: 373 SDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAAQDQLLHLASANGA 552
DAT NLN INK G KPW LTFSFGRALQASVL WKGKKENV AAQ++LL LA ANGA
Sbjct: 278 LDATKNLNEINKIPGPKPWALTFSFGRALQASVLATWKGKKENVHAAQEELLKLAKANGA 337
Query: 553 AAVGKFDGNLKTAAGGKSLFVANHAY 630
AAVGKF+GN+ T G KSLFVANHAY
Sbjct: 338 AAVGKFEGNMGTTLGDKSLFVANHAY 363
>sp|P53448|ALDOC_CARAU Fructose-bisphosphate aldolase C (Brain-type aldolase)
Length = 363
Score = 276 bits (705), Expect = 5e-74
Identities = 139/204 (68%), Positives = 163/204 (79%)
Frame = +1
Query: 19 SHQAMLENANVLARYASICQQNAIVPIVEPEVLPDGNHSLEEAQKVTEEVLSYVYKALAD 198
S A++ENANVLARYASICQQN IVPIVEPE+LPDG+H L+ Q VTE+VL+ YKAL+D
Sbjct: 160 SELAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAACYKALSD 219
Query: 199 HHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPAVAGVTFLSGGQSESD 378
HHVYLEGTLLKPNMVTAG SC TK++ ++ A ATV AL+RTVPPAV GVTFLSGGQSE +
Sbjct: 220 HHVYLEGTLLKPNMVTAGHSCPTKFSNQEIAMATVTALRRTVPPAVTGVTFLSGGQSEEE 279
Query: 379 ATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAAQDQLLHLASANGAAA 558
A+INLNAIN KPW LTFS+GRALQAS L AW+G KEN KAA ++ L A ANG AA
Sbjct: 280 ASINLNAINNCPLTKPWALTFSYGRALQASALSAWRGVKENEKAATEEFLKRAEANGLAA 339
Query: 559 VGKFDGNLKTAAGGKSLFVANHAY 630
GK+ + + G+SL+VANHAY
Sbjct: 340 QGKYVSSGMDGSAGQSLYVANHAY 363
>sp|P00883|ALDOA_RABIT Fructose-bisphosphate aldolase A (Muscle-type aldolase)
Length = 364
Score = 274 bits (701), Expect = 2e-73
Identities = 140/207 (67%), Positives = 167/207 (80%), Gaps = 1/207 (0%)
Frame = +1
Query: 13 TRSHQAMLENANVLARYASICQQNAIVPIVEPEVLPDGNHSLEEAQKVTEEVLSYVYKAL 192
T S A++ENANVLARYASICQQN IVPIVEPE+LPDG+H L+ Q VTE+VL+ VYKAL
Sbjct: 158 TPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKAL 217
Query: 193 ADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPAVAGVTFLSGGQSE 372
+DHH+YLEGTLLKPNMVT G +CT KY+ E+ A ATV AL+RTVPPAV GVTFLSGGQSE
Sbjct: 218 SDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATVTALRRTVPPAVTGVTFLSGGQSE 277
Query: 373 SDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAAQDQLLHLASANGA 552
+A+INLNAINK KPW LTFS+GRALQAS L+AW GKKEN+KAAQ++ + A AN
Sbjct: 278 EEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSL 337
Query: 553 AAVGKFDGNLKT-AAGGKSLFVANHAY 630
A GK+ + + AA +SLF++NHAY
Sbjct: 338 ACQGKYTPSGQAGAAASESLFISNHAY 364
>sp|P05064|ALDOA_MOUSE Fructose-bisphosphate aldolase A (Muscle-type aldolase) (Aldolase
1)
Length = 364
Score = 274 bits (700), Expect = 2e-73
Identities = 140/207 (67%), Positives = 168/207 (81%), Gaps = 1/207 (0%)
Frame = +1
Query: 13 TRSHQAMLENANVLARYASICQQNAIVPIVEPEVLPDGNHSLEEAQKVTEEVLSYVYKAL 192
T S A++ENANVLARYASICQQN IVPIVEPE+LPDG+H L+ Q VTE+VL+ VYKAL
Sbjct: 158 TPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKAL 217
Query: 193 ADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPAVAGVTFLSGGQSE 372
+DHHVYLEGTLLKPNMVT G +CT K++ E+ A ATV AL+RTVPPAV GVTFLSGGQSE
Sbjct: 218 SDHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAMATVTALRRTVPPAVTGVTFLSGGQSE 277
Query: 373 SDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAAQDQLLHLASANGA 552
+A+INLNAINK KPW LTFS+GRALQAS L+AW GKKEN+KAAQ++ + A AN
Sbjct: 278 EEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYIKRALANSL 337
Query: 553 AAVGKFDGNLKT-AAGGKSLFVANHAY 630
A GK+ + ++ AA +SLF++NHAY
Sbjct: 338 ACQGKYTPSGQSGAAASESLFISNHAY 364
>sp|P05065|ALDOA_RAT Fructose-bisphosphate aldolase A (Muscle-type aldolase)
Length = 364
Score = 274 bits (700), Expect = 2e-73
Identities = 140/207 (67%), Positives = 168/207 (81%), Gaps = 1/207 (0%)
Frame = +1
Query: 13 TRSHQAMLENANVLARYASICQQNAIVPIVEPEVLPDGNHSLEEAQKVTEEVLSYVYKAL 192
T S A++ENANVLARYASICQQN IVPIVEPE+LPDG+H L+ Q VTE+VL+ VYKAL
Sbjct: 158 TPSSLAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKAL 217
Query: 193 ADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPAVAGVTFLSGGQSE 372
+DHHVYLEGTLLKPNMVT G +CT K++ E+ A ATV AL+RTVPPAV GVTFLSGGQSE
Sbjct: 218 SDHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAMATVTALRRTVPPAVPGVTFLSGGQSE 277
Query: 373 SDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAAQDQLLHLASANGA 552
+A+INLNAINK KPW LTFS+GRALQAS L+AW GKKEN+KAAQ++ + A AN
Sbjct: 278 EEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYIKRALANSL 337
Query: 553 AAVGKFDGNLKT-AAGGKSLFVANHAY 630
A GK+ + ++ AA +SLF++NHAY
Sbjct: 338 ACQGKYTPSGQSGAAASESLFISNHAY 364
>sp|P53445|ALF1_LAMJA Fructose-bisphosphate aldolase, muscle type
Length = 363
Score = 273 bits (698), Expect = 4e-73
Identities = 137/206 (66%), Positives = 164/206 (79%)
Frame = +1
Query: 13 TRSHQAMLENANVLARYASICQQNAIVPIVEPEVLPDGNHSLEEAQKVTEEVLSYVYKAL 192
T S +++ENANVLARYA+ICQQN +VPIVEPE+LPDG+H L+ Q +TE+VL+ YKAL
Sbjct: 158 TPSRLSIVENANVLARYATICQQNGLVPIVEPEILPDGDHDLKTCQYITEKVLAATYKAL 217
Query: 193 ADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPAVAGVTFLSGGQSE 372
+DHHVYLEGTLLKPNMVT G + EQ A AT+ AL+RTVPPAV G+TFLSGGQSE
Sbjct: 218 SDHHVYLEGTLLKPNMVTVGTAAPASTRPEQVAMATLTALRRTVPPAVPGITFLSGGQSE 277
Query: 373 SDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAAQDQLLHLASANGA 552
DA+I+LNAINK H KPW LTFS+GRALQASVL+AW GKKEN+KAAQD+L+ A NG
Sbjct: 278 EDASIHLNAINKLHLIKPWALTFSYGRALQASVLKAWGGKKENLKAAQDELMRRAKINGQ 337
Query: 553 AAVGKFDGNLKTAAGGKSLFVANHAY 630
A+ G++ AA G+SLFVANHAY
Sbjct: 338 ASKGEYKPTGTGAAAGESLFVANHAY 363
>sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A (Muscle-type aldolase) (Lung
cancer antigen NY-LU-1)
Length = 364
Score = 273 bits (697), Expect = 5e-73
Identities = 139/207 (67%), Positives = 167/207 (80%), Gaps = 1/207 (0%)
Frame = +1
Query: 13 TRSHQAMLENANVLARYASICQQNAIVPIVEPEVLPDGNHSLEEAQKVTEEVLSYVYKAL 192
T S A++ENANVLARYASICQQN IVPIVEPE+LPDG+H L+ Q VTE+VL+ VYKAL
Sbjct: 158 TPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKAL 217
Query: 193 ADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPAVAGVTFLSGGQSE 372
+DHH+YLEGTLLKPNMVT G +CT K++ E+ A ATV AL+RTVPPAV G+TFLSGGQSE
Sbjct: 218 SDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSE 277
Query: 373 SDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAAQDQLLHLASANGA 552
+A+INLNAINK KPW LTFS+GRALQAS L+AW GKKEN+KAAQ++ + A AN
Sbjct: 278 EEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSL 337
Query: 553 AAVGKFDGNLKT-AAGGKSLFVANHAY 630
A GK+ + + AA +SLFV+NHAY
Sbjct: 338 ACQGKYTPSGQAGAAASESLFVSNHAY 364
>sp|P07764|ALF_DROME Fructose-bisphosphate aldolase
Length = 361
Score = 272 bits (695), Expect = 8e-73
Identities = 145/206 (70%), Positives = 164/206 (79%)
Frame = +1
Query: 13 TRSHQAMLENANVLARYASICQQNAIVPIVEPEVLPDGNHSLEEAQKVTEEVLSYVYKAL 192
T S+Q++LENANVLARYASICQ IVPIVEPEVLPDG+H L+ AQKVTE VL+ VYKAL
Sbjct: 158 TPSYQSILENANVLARYASICQSQRIVPIVEPEVLPDGDHDLDRAQKVTETVLAAVYKAL 217
Query: 193 ADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPAVAGVTFLSGGQSE 372
+DHHVYLEGTLLKPNMVTAGQS K T E+ A ATV+AL+RTVP AV GVTFLSGGQSE
Sbjct: 218 SDHHVYLEGTLLKPNMVTAGQS-AKKNTPEEIALATVQALRRTVPAAVTGVTFLSGGQSE 276
Query: 373 SDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAAQDQLLHLASANGA 552
+AT+NL+AIN +PW LTFS+GRALQASVL AW GKKEN+ A Q++LL A ANG
Sbjct: 277 EEATVNLSAINNVPLIRPWALTFSYGRALQASVLRAWAGKKENIAAGQNELLKRAKANGD 336
Query: 553 AAVGKFDGNLKTAAGGKSLFVANHAY 630
AA GK+ AG SLFVANHAY
Sbjct: 337 AAQGKYVAG-SAGAGSGSLFVANHAY 361
>sp|P46563|ALF2_CAEEL Fructose-bisphosphate aldolase 2 (Aldolase CE-2) (CE2)
Length = 366
Score = 271 bits (694), Expect = 1e-72
Identities = 141/206 (68%), Positives = 158/206 (76%)
Frame = +1
Query: 13 TRSHQAMLENANVLARYASICQQNAIVPIVEPEVLPDGNHSLEEAQKVTEEVLSYVYKAL 192
T SH MLENANVLARYASICQ N +VPIVEPEVL DG H L AQKVTE+VL++VYKAL
Sbjct: 161 TPSHLGMLENANVLARYASICQANGLVPIVEPEVLCDGEHDLARAQKVTEQVLAFVYKAL 220
Query: 193 ADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATVKALQRTVPPAVAGVTFLSGGQSE 372
ADHHVYLEGTLLKPNMVT GQS +K + E ATV AL+R VP AV G+TFLSGGQSE
Sbjct: 221 ADHHVYLEGTLLKPNMVTPGQSSASKASHEAIGLATVTALRRGVPAAVPGITFLSGGQSE 280
Query: 373 SDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAWKGKKENVKAAQDQLLHLASANGA 552
DAT NLNAIN KPW LTFS+GRALQASVL+AW GK EN+ AAQ LLH + ANG
Sbjct: 281 LDATANLNAINSVQLGKPWKLTFSYGRALQASVLKAWGGKDENIAAAQKTLLHRSKANGD 340
Query: 553 AAVGKFDGNLKTAAGGKSLFVANHAY 630
A++GK+ G A +SLFVA H+Y
Sbjct: 341 ASLGKYAGEDAAGAAAESLFVAKHSY 366
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,256,937
Number of Sequences: 369166
Number of extensions: 1890777
Number of successful extensions: 4996
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4816
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4963
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6728100400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)