Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_M06
(318 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P35603|AP50_CAEEL Clathrin coat assembly protein AP50 (C... 83 2e-16
sp|P84092|AP2M1_RAT Clathrin coat assembly protein AP50 (Cl... 82 3e-16
sp|P54672|AP50_DICDI Clathrin coat assembly protein AP50 (C... 42 6e-04
sp|P35602|AP47_CAEEL Clathrin coat assembly protein AP47 (C... 38 0.006
sp|Q9HFE5|AP54_SCHPO Clathrin coat assembly protein AP54 (C... 37 0.011
sp|Q9Y6Q5|AP1M2_HUMAN Adaptor-related protein complex 1, mu... 37 0.014
sp|Q9WVP1|AP1M2_MOUSE Adaptor-related protein complex 1, mu... 37 0.014
sp|Q9BXS5|AP1M1_HUMAN Adaptor-related protein complex 1, mu... 37 0.018
sp|P35585|AP1M1_MOUSE Adaptor-related protein complex 1, mu... 37 0.018
sp|Q00776|AP54_YEAST Clathrin coat assembly protein AP54 (C... 37 0.018
>sp|P35603|AP50_CAEEL Clathrin coat assembly protein AP50 (Clathrin coat-associated
protein AP50) (Plasma membrane adaptor AP-2 50 kDa
protein) (Clathrin assembly protein complex 2 medium
chain) (Dumpy protein 23)
Length = 441
Score = 83.2 bits (204), Expect = 2e-16
Identities = 37/41 (90%), Positives = 39/41 (95%)
Frame = +3
Query: 6 APSGFKVRYLKVFESKLNYSDHEVIKWVRYIGKSGLYETRC 128
APSG KVRYLKVFE KLNYSDH+VIKWVRYIG+SGLYETRC
Sbjct: 401 APSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETRC 441
>sp|P84092|AP2M1_RAT Clathrin coat assembly protein AP50 (Clathrin coat-associated
protein AP50) (Plasma membrane adaptor AP-2 50 kDa
protein) (Clathrin assembly protein complex 2 medium
chain) (AP-2 mu 2 chain)
sp|P84091|AP2M1_MOUSE Clathrin coat assembly protein AP50 (Clathrin coat-associated
protein AP50) (Plasma membrane adaptor AP-2 50 kDa
protein) (Clathrin assembly protein complex 2 medium
chain) (AP-2 mu 2 chain)
sp|Q96CW1|AP2M1_HUMAN Clathrin coat assembly protein AP50 (Clathrin coat-associated
protein AP50) (Plasma membrane adaptor AP-2 50 kDa
protein) (HA2 50 kDa subunit) (Clathrin assembly protein
complex 2 medium chain) (AP-2 mu 2 chain)
Length = 435
Score = 82.4 bits (202), Expect = 3e-16
Identities = 36/41 (87%), Positives = 39/41 (95%)
Frame = +3
Query: 6 APSGFKVRYLKVFESKLNYSDHEVIKWVRYIGKSGLYETRC 128
APSG KVRYLKVFE KLNYSDH+VIKWVRYIG+SG+YETRC
Sbjct: 395 APSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC 435
>sp|P54672|AP50_DICDI Clathrin coat assembly protein AP50 (Clathrin coat-associated
protein AP50) (Plasma membrane adaptor AP-2 50 kDa
protein) (Clathrin assembly protein complex 2 medium
chain)
Length = 439
Score = 41.6 bits (96), Expect = 6e-04
Identities = 22/38 (57%), Positives = 27/38 (71%)
Frame = +3
Query: 12 SGFKVRYLKVFESKLNYSDHEVIKWVRYIGKSGLYETR 125
SGF VR+LKV E K NY+ IKWVRY+ K+G Y+ R
Sbjct: 405 SGFSVRFLKVVE-KSNYTP---IKWVRYLTKAGTYQNR 438
>sp|P35602|AP47_CAEEL Clathrin coat assembly protein AP47 (Clathrin coat-associated
protein AP47) (Golgi adaptor AP-1 47 kDa protein) (HA1
47 kDa subunit) (Clathrin assembly protein assembly
protein complex 1 medium chain) (Uncoordinated protein
101)
Length = 422
Score = 38.1 bits (87), Expect = 0.006
Identities = 18/38 (47%), Positives = 25/38 (65%)
Frame = +3
Query: 12 SGFKVRYLKVFESKLNYSDHEVIKWVRYIGKSGLYETR 125
SG +VRYLK+ E S ++ + WVRYI ++G YE R
Sbjct: 387 SGIQVRYLKIIEK----SGYQALPWVRYITQNGEYEMR 420
>sp|Q9HFE5|AP54_SCHPO Clathrin coat assembly protein AP54 (Clathrin coat-associated
protein AP54) (Golgi adaptor AP-1 54 kDa protein)
(Clathrin assembly protein complex 1 medium chain)
Length = 426
Score = 37.4 bits (85), Expect = 0.011
Identities = 17/33 (51%), Positives = 23/33 (69%)
Frame = +3
Query: 12 SGFKVRYLKVFESKLNYSDHEVIKWVRYIGKSG 110
SG +VRYLK+ E KLNY + WVRY+ ++G
Sbjct: 390 SGIQVRYLKITEPKLNY---HAMPWVRYVTQNG 419
>sp|Q9Y6Q5|AP1M2_HUMAN Adaptor-related protein complex 1, mu 2 subunit (Mu-adaptin 2)
(Adaptor protein complex AP-1 mu-2 subunit) (Golgi
adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly
protein assembly protein complex 1 medium chain 2)
(AP-mu chain family member mu1B)
Length = 423
Score = 37.0 bits (84), Expect = 0.014
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +3
Query: 12 SGFKVRYLKVFESKLNYSDHEVIKWVRYIGKSGLYETR 125
SG +VRY+K+ E S ++ + WVRYI +SG Y+ R
Sbjct: 388 SGIQVRYMKIIEK----SGYQALPWVRYITQSGDYQLR 421
>sp|Q9WVP1|AP1M2_MOUSE Adaptor-related protein complex 1, mu 2 subunit (Mu-adaptin 2)
(Adaptor protein complex AP-1 mu-2 subunit) (Golgi
adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly
protein assembly protein complex 1 medium chain 2)
(AP-mu chain family member mu1B)
Length = 423
Score = 37.0 bits (84), Expect = 0.014
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +3
Query: 12 SGFKVRYLKVFESKLNYSDHEVIKWVRYIGKSGLYETR 125
SG +VRY+K+ E S ++ + WVRYI +SG Y+ R
Sbjct: 388 SGIQVRYMKIIEK----SGYQALPWVRYITQSGDYQLR 421
>sp|Q9BXS5|AP1M1_HUMAN Adaptor-related protein complex 1, mu 1 subunit (Mu-adaptin 1)
(Adaptor protein complex AP-1 mu-1 subunit) (Golgi
adaptor HA1/AP1 adaptin mu-1 subunit) (Clathrin assembly
protein assembly protein complex 1 medium chain 1)
(Clathrin coat assembly protein AP47) (Clathrin
coat-associated protein AP47) (AP-mu chain family member
mu1A)
Length = 423
Score = 36.6 bits (83), Expect = 0.018
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +3
Query: 12 SGFKVRYLKVFESKLNYSDHEVIKWVRYIGKSGLYETR 125
SG +VRYLK+ E S ++ + WVRYI ++G Y+ R
Sbjct: 388 SGIQVRYLKIIEK----SGYQALPWVRYITQNGDYQLR 421
>sp|P35585|AP1M1_MOUSE Adaptor-related protein complex 1, mu 1 subunit (Mu-adaptin 1)
(Adaptor protein complex AP-1 mu-1 subunit) (Golgi
adaptor HA1/AP1 adaptin mu-1 subunit) (Clathrin assembly
protein assembly protein complex 1 medium chain 1)
(Clathrin coat assembly protein AP47) (Clathrin
coat-associated protein AP47) (AP-mu chain family member
mu1A)
Length = 423
Score = 36.6 bits (83), Expect = 0.018
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +3
Query: 12 SGFKVRYLKVFESKLNYSDHEVIKWVRYIGKSGLYETR 125
SG +VRYLK+ E S ++ + WVRYI ++G Y+ R
Sbjct: 388 SGIQVRYLKIIEK----SGYQALPWVRYITQNGDYQLR 421
>sp|Q00776|AP54_YEAST Clathrin coat assembly protein AP54 (Clathrin coat-associated
protein AP54) (Golgi adaptor AP-1 54 kDa protein) (HA1
54 kDa subunit) (Clathrin assembly protein complex 1
medium chain)
Length = 475
Score = 36.6 bits (83), Expect = 0.018
Identities = 18/33 (54%), Positives = 22/33 (66%)
Frame = +3
Query: 12 SGFKVRYLKVFESKLNYSDHEVIKWVRYIGKSG 110
SG +VRYLK+ E KL Y + WVRYI +SG
Sbjct: 438 SGIQVRYLKINEPKLQYKSY---PWVRYITQSG 467
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,912,827
Number of Sequences: 369166
Number of extensions: 574089
Number of successful extensions: 1319
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1296
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1315
length of database: 68,354,980
effective HSP length: 74
effective length of database: 54,684,590
effective search space used: 1695222290
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)