Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_L21
(562 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P00889|CISY_PIG Citrate synthase, mitochondrial precursor 290 2e-78
sp|O75390|CISY_HUMAN Citrate synthase, mitochondrial precursor 290 2e-78
sp|Q9CZU6|CISY_MOUSE Citrate synthase, mitochondrial precursor 287 1e-77
sp|P23007|CISY_CHICK Citrate synthase, mitochondrial 271 8e-73
sp|P34575|CISY_CAEEL Probable citrate synthase, mitochondri... 269 3e-72
sp|P51044|CISY_ASPNG Citrate synthase, mitochondrial precursor 225 7e-59
sp|O00098|CISY_EMENI Citrate synthase, mitochondrial precursor 219 3e-57
sp|P79024|CISY_CANTR Citrate synthase, mitochondrial precursor 217 2e-56
sp|P00890|CISY1_YEAST Citrate synthase, mitochondrial precu... 216 3e-56
sp|Q10306|CISY_SCHPO Probable citrate synthase, mitochondri... 214 1e-55
>sp|P00889|CISY_PIG Citrate synthase, mitochondrial precursor
Length = 464
Score = 290 bits (742), Expect = 2e-78
Identities = 132/186 (70%), Positives = 161/186 (86%)
Frame = +1
Query: 1 GEVTINMMYGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLF 180
G++T++MMYGGMRG+KGLV ETSVLDP+EGIRFRGYSIPECQK+LPK++GGE+PLPEGLF
Sbjct: 61 GQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKMLPKAKGGEEPLPEGLF 120
Query: 181 FLLLTGKIPTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESK 360
+LL+TG+IPTEEQV W+SKEWA RA LP HVV+M++NFP++LHPMSQL AA ALNSES
Sbjct: 121 WLLVTGQIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESN 180
Query: 361 FVKAYHEGVSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTCVGCIDNSKDWSENF 540
F +AY EG+ ++ YWE +YED MDLIAKL VAA IYRNLYR+G+ +G ID+ DWS NF
Sbjct: 181 FARAYAEGIHRTKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSKLDWSHNF 240
Query: 541 VRMIGY 558
M+GY
Sbjct: 241 TNMLGY 246
>sp|O75390|CISY_HUMAN Citrate synthase, mitochondrial precursor
Length = 466
Score = 290 bits (742), Expect = 2e-78
Identities = 132/186 (70%), Positives = 163/186 (87%)
Frame = +1
Query: 1 GEVTINMMYGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLF 180
G++T++MMYGGMRG+KGLV ETSVLDP+EGIRFRG+SIPECQK+LPK++GGE+PLPEGLF
Sbjct: 61 GQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEGLF 120
Query: 181 FLLLTGKIPTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESK 360
+LL+TG IPTEEQV W+SKEWA RA LP HVV+M++NFP++LHPMSQL AA ALNSES
Sbjct: 121 WLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESN 180
Query: 361 FVKAYHEGVSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTCVGCIDNSKDWSENF 540
F +AY +G+S++ YWE +YEDSMDLIAKL VAA IYRNLYR+G+ +G ID++ DWS NF
Sbjct: 181 FARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNF 240
Query: 541 VRMIGY 558
M+GY
Sbjct: 241 TNMLGY 246
>sp|Q9CZU6|CISY_MOUSE Citrate synthase, mitochondrial precursor
Length = 464
Score = 287 bits (735), Expect = 1e-77
Identities = 130/186 (69%), Positives = 162/186 (87%)
Frame = +1
Query: 1 GEVTINMMYGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLF 180
G++T++MMYGGMRG+KGLV ETSVLDP+EGIRFRGYSIPECQK+LPK++GGE+PLPEGLF
Sbjct: 61 GQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKMLPKAKGGEEPLPEGLF 120
Query: 181 FLLLTGKIPTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESK 360
+LL+TG++PTEEQV W+S+EWA RA LP HVV+M++NFP++LHPMSQL AA ALNSES
Sbjct: 121 WLLVTGQMPTEEQVSWLSREWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESN 180
Query: 361 FVKAYHEGVSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTCVGCIDNSKDWSENF 540
F +AY EG++++ YWE +YED MDLIAKL VAA IYRNLYR+G+ +G ID+ DWS NF
Sbjct: 181 FARAYAEGMNRAKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSRLDWSHNF 240
Query: 541 VRMIGY 558
M+GY
Sbjct: 241 TNMLGY 246
>sp|P23007|CISY_CHICK Citrate synthase, mitochondrial
Length = 433
Score = 271 bits (693), Expect = 8e-73
Identities = 126/186 (67%), Positives = 153/186 (82%)
Frame = +1
Query: 1 GEVTINMMYGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLF 180
G++T++M YGGMRG+KGLV ETSVLDP+EGIRFRG+SIPECQK+LPK G +PLPEGLF
Sbjct: 34 GQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGXGGEPLPEGLF 93
Query: 181 FLLLTGKIPTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESK 360
+LL+TG+IPT QV W+SKEWA RA LP HVV+M++NFP++LHPMSQL AA ALNSES
Sbjct: 94 WLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESN 153
Query: 361 FVKAYHEGVSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTCVGCIDNSKDWSENF 540
F +AY EG+ ++ YWE VYE +MDLIAKL VAA IYRNLYR G+ +G ID+ DWS NF
Sbjct: 154 FARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNF 213
Query: 541 VRMIGY 558
M+GY
Sbjct: 214 TNMLGY 219
>sp|P34575|CISY_CAEEL Probable citrate synthase, mitochondrial precursor
Length = 468
Score = 269 bits (688), Expect = 3e-72
Identities = 126/185 (68%), Positives = 154/185 (83%)
Frame = +1
Query: 7 VTINMMYGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLFFL 186
V I+M+YGGMR +KG+VTETSVLDPEEGIRFRGYSIPECQK+LPK++GGE+PLPE +++L
Sbjct: 65 VNIDMIYGGMRSMKGMVTETSVLDPEEGIRFRGYSIPECQKLLPKAKGGEEPLPEAIWWL 124
Query: 187 LLTGKIPTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFV 366
L TG +P+E Q I+KEW +RADLP HVV M++NFP +LHPM+Q +AA AALN+ESKF
Sbjct: 125 LCTGDVPSEAQTAAITKEWNARADLPTHVVRMLDNFPDNLHPMAQFIAAIAALNNESKFA 184
Query: 367 KAYHEGVSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTCVGCIDNSKDWSENFVR 546
AY GV+K+ YWE YEDSMDL+AKL TVAA+IYRNLYRDG+ V ID KDWS NF
Sbjct: 185 GAYARGVAKASYWEYAYEDSMDLLAKLPTVAAIIYRNLYRDGSAVSVIDPKKDWSANFSS 244
Query: 547 MIGYE 561
M+GY+
Sbjct: 245 MLGYD 249
>sp|P51044|CISY_ASPNG Citrate synthase, mitochondrial precursor
Length = 475
Score = 225 bits (573), Expect = 7e-59
Identities = 110/186 (59%), Positives = 140/186 (75%)
Frame = +1
Query: 1 GEVTINMMYGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLF 180
GEVT++ YGG RG+K LV E SVLD EEGIRFRG +IPECQ++LPK+ GG++PLPEGLF
Sbjct: 70 GEVTLDQAYGGARGVKCLVWEGSVLDSEEGIRFRGRTIPECQELLPKAPGGQEPLPEGLF 129
Query: 181 FLLLTGKIPTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESK 360
+LLLTG+IPTE+QV+ +S EWA+R+DLP + +I+ PS+LHPMSQ A AL ES
Sbjct: 130 WLLLTGEIPTEQQVRDLSAEWAARSDLPKFIEELIDRCPSTLHPMSQFSLAVTALEHESA 189
Query: 361 FVKAYHEGVSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTCVGCIDNSKDWSENF 540
F KAY +G++K YW +EDSMDLIAKL T+AA IYRN+++DG V I KD+S N
Sbjct: 190 FAKAYAKGINKKDYWNYTFEDSMDLIAKLPTIAAKIYRNVFKDGK-VAPIQKDKDYSYNL 248
Query: 541 VRMIGY 558
+GY
Sbjct: 249 ANQLGY 254
>sp|O00098|CISY_EMENI Citrate synthase, mitochondrial precursor
Length = 474
Score = 219 bits (559), Expect = 3e-57
Identities = 106/186 (56%), Positives = 139/186 (74%)
Frame = +1
Query: 1 GEVTINMMYGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLF 180
GE+T++ YGG RG+K LV E SVLD EEGIRFRG +IPECQK+LPK+ GGE+PLPEGLF
Sbjct: 70 GELTLDQAYGGARGVKCLVWEGSVLDSEEGIRFRGLTIPECQKLLPKAPGGEEPLPEGLF 129
Query: 181 FLLLTGKIPTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESK 360
+LLLTG++P+E+QV+ +S EWA+R+DLP + +I+ PS+LHPM+Q A AL ES
Sbjct: 130 WLLLTGEVPSEQQVRDLSAEWAARSDLPKFIEELIDRVPSTLHPMAQFSLAVTALEHESA 189
Query: 361 FVKAYHEGVSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTCVGCIDNSKDWSENF 540
F KA +G++K YW +EDSMDLIAKL T+AA IYRN+++DG V I KD+S N
Sbjct: 190 FAKATAKGINKKEYWHYTFEDSMDLIAKLPTIAAKIYRNVFKDGK-VAPIQKDKDYSYNL 248
Query: 541 VRMIGY 558
+G+
Sbjct: 249 ANQLGF 254
>sp|P79024|CISY_CANTR Citrate synthase, mitochondrial precursor
Length = 467
Score = 217 bits (552), Expect = 2e-56
Identities = 106/186 (56%), Positives = 137/186 (73%)
Frame = +1
Query: 1 GEVTINMMYGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLF 180
GEV + YGGMRGIKGLV E SVLDP EGIRFRG +IP+ QK LPK+ GGE+PLPE LF
Sbjct: 60 GEVLLEQAYGGMRGIKGLVWEGSVLDPIEGIRFRGRTIPDIQKELPKAPGGEEPLPEALF 119
Query: 181 FLLLTGKIPTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESK 360
+LLLTG++PTE Q + +S+E+A+R+ LP HV +I+ PS LHPM+Q A AL SES+
Sbjct: 120 WLLLTGEVPTEAQTRALSEEFAARSALPKHVEELIDRSPSHLHPMAQFSIAVTALESESQ 179
Query: 361 FVKAYHEGVSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTCVGCIDNSKDWSENF 540
F KAY +GV KS YW+ YEDS++L+AKL T+AA IYRN++ DG ID+ D+ N
Sbjct: 180 FAKAYAKGVHKSEYWKYTYEDSIELLAKLPTIAAKIYRNVFHDGKLPAQIDSKLDYGANL 239
Query: 541 VRMIGY 558
++G+
Sbjct: 240 ASLLGF 245
>sp|P00890|CISY1_YEAST Citrate synthase, mitochondrial precursor
Length = 479
Score = 216 bits (550), Expect = 3e-56
Identities = 102/187 (54%), Positives = 139/187 (74%)
Frame = +1
Query: 1 GEVTINMMYGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLF 180
GEV + YGGMRGIKGLV E SVLDPEEGIRFRG +IPE Q+ LPK++G +PLPE LF
Sbjct: 73 GEVLLEQAYGGMRGIKGLVWEGSVLDPEEGIRFRGRTIPEIQRELPKAEGSTEPLPEALF 132
Query: 181 FLLLTGKIPTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESK 360
+LLLTG+IPT+ QVK +S + A+R+++P HV+ ++++ P LHPM+Q A AL SESK
Sbjct: 133 WLLLTGEIPTDAQVKALSADLAARSEIPEHVIQLLDSLPKDLHPMAQFSIAVTALESESK 192
Query: 361 FVKAYHEGVSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTCVGCIDNSKDWSENF 540
F KAY +GVSK YW +EDS+DL+ KL +A+ IYRN+++DG + D + D+ +N
Sbjct: 193 FAKAYAQGVSKKEYWSYTFEDSLDLLGKLPVIASKIYRNVFKDGK-ITSTDPNADYGKNL 251
Query: 541 VRMIGYE 561
+++GYE
Sbjct: 252 AQLLGYE 258
>sp|Q10306|CISY_SCHPO Probable citrate synthase, mitochondrial precursor
Length = 473
Score = 214 bits (545), Expect = 1e-55
Identities = 106/186 (56%), Positives = 132/186 (70%)
Frame = +1
Query: 1 GEVTINMMYGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLF 180
GEVTIN MYGG RG++ L+ E SVLDP EGIRFRGY+IPECQK+LP S G+QPLPE LF
Sbjct: 70 GEVTINQMYGGARGVRSLIWEGSVLDPNEGIRFRGYTIPECQKLLPSSPNGKQPLPESLF 129
Query: 181 FLLLTGKIPTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESK 360
+LL+TG+IPT QV+ +S +WA+R+ LP V +I+ P +LHPM+Q A AL +S
Sbjct: 130 WLLVTGEIPTLSQVQALSADWAARSQLPKFVEELIDRCPPTLHPMAQFSLAVTALEHDSA 189
Query: 361 FVKAYHEGVSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTCVGCIDNSKDWSENF 540
F KAY G++K YW+ YED MDLIAK +A IYRNLYRDG V I KD S NF
Sbjct: 190 FAKAYERGMNKHDYWKYEYEDCMDLIAKTVPIAGRIYRNLYRDGV-VAPIQMDKDHSYNF 248
Query: 541 VRMIGY 558
++G+
Sbjct: 249 ANVLGF 254
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.317 0.134 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,035,994
Number of Sequences: 369166
Number of extensions: 1386936
Number of successful extensions: 3348
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3246
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3311
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4029688280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)