Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_L15
(779 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q924T7|RNF31_MOUSE RING finger protein 31 81 4e-15
sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-betwe... 78 3e-14
sp|P50636|RNF19_MOUSE RING finger protein 19 (XY body prote... 54 5e-07
sp|Q9NV58|RNF19_HUMAN RING finger protein 19 (Dorfin) (Doub... 54 5e-07
sp|P50876|UB7I4_HUMAN Ubiquitin-conjugating enzyme 7-intera... 52 2e-06
sp|Q925F3|UB7I4_MOUSE Ubiquitin-conjugating enzyme 7-intera... 50 5e-06
sp|Q22431|ARI2_CAEEL Probable ariadne-2 protein (Ari-2) 49 2e-05
sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 48 3e-05
sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 47 8e-05
sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 46 1e-04
>sp|Q924T7|RNF31_MOUSE RING finger protein 31
Length = 1066
Score = 80.9 bits (198), Expect = 4e-15
Identities = 50/175 (28%), Positives = 79/175 (45%), Gaps = 7/175 (4%)
Frame = +2
Query: 275 KMLHLKQAITDQETIDGAINFLQKACELCCTEYPMPEMIGFITCQHEFCKQCVLNWLEET 454
++L + +A+ + L + C +C P M I+C+ C +C
Sbjct: 668 ELLDVVEAVRHSQDRAFLRRLLAQECAVCGWALPRNRMQALISCECTICPECFRQHFTIA 727
Query: 455 IVTKYPCKWNCPYCPDDDYLNVDKNLHYG-----QLRGILSEKDNLISIFESKLLQEQLM 619
+ K+ CP C D + + L Y QLR L + ++F KL + LM
Sbjct: 728 LKEKHITDMVCPACGRPDLTDDAQLLSYFSTLDIQLRESLDP--DAYALFHKKLTEAVLM 785
Query: 620 KSPNFHWCANEECTNGF--EAEGIEKILCPSCKTPMCVKCNRKWQEAHENKSCQE 778
+ P F WCA +C+ GF E E +E CP C CV+C R+W+E H +SC++
Sbjct: 786 RDPKFLWCA--QCSFGFIYEREQLEAT-CPQCHQTFCVRCKRQWEEQHRGRSCED 837
>sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-between-RING-finger
ubiquitin-associated domain protein)
Length = 1072
Score = 77.8 bits (190), Expect = 3e-14
Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 5/152 (3%)
Frame = +2
Query: 338 LQKACELCCTEYPMPEMIGFITCQHEFCKQCVLNWLEETIVTKYPCKWNCPYCPDDDYLN 517
L + C +C P M +C+ C C + K+ CP C D +
Sbjct: 695 LAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTD 754
Query: 518 VDKNLHYGQLRGIL---SEKDNLISIFESKLLQEQLMKSPNFHWCANEECTNGF--EAEG 682
+ L Y I S + + ++F KL + LM+ P F WCA +C+ GF E E
Sbjct: 755 DTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCA--QCSFGFIYEREQ 812
Query: 683 IEKILCPSCKTPMCVKCNRKWQEAHENKSCQE 778
+E CP C CV+C R+W+E H +SC++
Sbjct: 813 LEAT-CPQCHQTFCVRCKRQWEEQHRGRSCED 843
>sp|P50636|RNF19_MOUSE RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis
expressed protein GEG-154) (UBCM4-interacting protein
117) (UIP117)
Length = 840
Score = 53.9 bits (128), Expect = 5e-07
Identities = 37/146 (25%), Positives = 59/146 (40%), Gaps = 5/146 (3%)
Frame = +2
Query: 350 CELCCTEYPMPEMIGFITCQHEFCKQCVLNWLEETIVTKYPCKWNCPYCPDDDYLNVDKN 529
C LC + +TC H C C+ +L I ++ +CP C +
Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEI-SESRVNISCPECTE--------R 182
Query: 530 LHYGQLRGILSEKDNLISIFESKLLQEQLMKSPNFHWCANEEC---TNGFEAEGIEKILC 700
+ +R ILS+ D L+ +E +L+ L+ P+ WC +C F K+ C
Sbjct: 183 FNPHDIRLILSD-DVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTC 241
Query: 701 --PSCKTPMCVKCNRKWQEAHENKSC 772
C T C C + W H N++C
Sbjct: 242 GREGCGTEFCYHCKQIW---HPNQTC 264
>sp|Q9NV58|RNF19_HUMAN RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38
protein)
Length = 838
Score = 53.9 bits (128), Expect = 5e-07
Identities = 37/146 (25%), Positives = 59/146 (40%), Gaps = 5/146 (3%)
Frame = +2
Query: 350 CELCCTEYPMPEMIGFITCQHEFCKQCVLNWLEETIVTKYPCKWNCPYCPDDDYLNVDKN 529
C LC + +TC H C C+ +L I ++ +CP C +
Sbjct: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEI-SESRVNISCPECTE--------R 182
Query: 530 LHYGQLRGILSEKDNLISIFESKLLQEQLMKSPNFHWCANEEC---TNGFEAEGIEKILC 700
+ +R ILS+ D L+ +E +L+ L+ P+ WC +C F K+ C
Sbjct: 183 FNPHDIRLILSD-DVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTC 241
Query: 701 --PSCKTPMCVKCNRKWQEAHENKSC 772
C T C C + W H N++C
Sbjct: 242 GREGCGTEFCYHCKQIW---HPNQTC 264
>sp|P50876|UB7I4_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 4
(UbcM4-interacting protein 4) (RING finger protein 144)
Length = 292
Score = 51.6 bits (122), Expect = 2e-06
Identities = 31/151 (20%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Frame = +2
Query: 347 ACELCCTEYPMPEMIGFITCQHEFCKQCVLNWLEETIVTKYPCKWNCP--YCPDDDYLNV 520
+C+LC EYP+ +M CQ FC C+ ++E I +CP CP +L
Sbjct: 19 SCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQE 78
Query: 521 DKNLHYGQLRGILSEKDNLISIFESKLLQEQLMKSPNFHWCANEECTNGFEAEGI----- 685
+ ++ +++ + ++ ++ + +++ P WC C + + +
Sbjct: 79 N------EIECMVAAE--IMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTP 130
Query: 686 EKILCPSCKTPMCVKCNRKWQEAHENKSCQE 778
+ + C +C+ C C W H + C E
Sbjct: 131 QPVQCKACRMEFCSTCKASW---HPGQGCPE 158
>sp|Q925F3|UB7I4_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 4
(UbcM4-interacting protein 4) (RING finger protein 144)
Length = 292
Score = 50.4 bits (119), Expect = 5e-06
Identities = 32/151 (21%), Positives = 62/151 (41%), Gaps = 7/151 (4%)
Frame = +2
Query: 347 ACELCCTEYPMPEMIGFITCQHEFCKQCVLNWLEETIVTKYPCKWNCP--YCPDDDYLNV 520
+C+LC EYP +M CQ FC C+ ++E I +CP CP +L
Sbjct: 19 SCKLCLGEYPAEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQE 78
Query: 521 DKNLHYGQLRGILSEKDNLISIFESKLLQEQLMKSPNFHWCANEECTNGFEAEGI----- 685
+ ++ +++ + ++ ++ + +++ P WC C + + I
Sbjct: 79 N------EIECMVAAE--IMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDIGLQTP 130
Query: 686 EKILCPSCKTPMCVKCNRKWQEAHENKSCQE 778
+ + C +C C C +W H + C E
Sbjct: 131 QLVQCKACDMEFCSACKARW---HPGQGCPE 158
>sp|Q22431|ARI2_CAEEL Probable ariadne-2 protein (Ari-2)
Length = 482
Score = 48.5 bits (114), Expect = 2e-05
Identities = 39/154 (25%), Positives = 65/154 (42%), Gaps = 12/154 (7%)
Frame = +2
Query: 350 CELCC----TEYPMPEMIGFITCQHEFCKQC----VLNWLEETIVTKYPC-KWNCP-YCP 499
C +C TE P +TC H FC+ C V + L E + ++ C + C Y P
Sbjct: 129 CSVCAMDGYTELP------HLTCGHCFCEHCWKSHVESRLSEGVASRIECMESECEVYAP 182
Query: 500 DDDYLNVDKNLHYGQLRGILSEKDNLISIFESKLLQEQLMKSPNFHWCANEECTNGFEAE 679
+ L++ KN +L+ +E LL++ + P+ +C EC +
Sbjct: 183 SEFVLSIIKNSPVIKLK------------YERFLLRDMVNSHPHLKFCVGNECPVIIRST 230
Query: 680 GIE--KILCPSCKTPMCVKCNRKWQEAHENKSCQ 775
++ ++ C C T CVKC + H SC+
Sbjct: 231 EVKPKRVTCMQCHTSFCVKCGADY---HAPTSCE 261
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein
interacting with PKC) (Protein kinase C-binding protein
beta-15)
Length = 498
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/150 (25%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Frame = +2
Query: 350 CELCCTEYPMPEMIGFITCQHEFCKQCVLNWLEETIVTKYPCKWNCPYCPDDDYLNVDKN 529
C +C + E + C H FC++C L+ TI + +CP+ D+ +
Sbjct: 270 CPVCYSVLAPGEAVVLRECLHTFCREC----LQGTIRNSQEAEVSCPFI--DNTYSCPGK 323
Query: 530 LHYGQLRGILSEKDNL------ISIFESKLLQEQLMKSPNFH-WCANEECTNGFEAEGIE 688
L ++R +LS +D +SI E++ K+P+ WC E+ N F
Sbjct: 324 LLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEF------ 377
Query: 689 KILCPSCKTPMCVKCNRKWQEAHENKSCQE 778
CP C C+ C + HE +C+E
Sbjct: 378 --TCPVCTRVNCLLC----KAIHERMNCRE 401
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3
(UbcM4-interacting protein 28)
Length = 498
Score = 46.6 bits (109), Expect = 8e-05
Identities = 38/150 (25%), Positives = 62/150 (41%), Gaps = 7/150 (4%)
Frame = +2
Query: 350 CELCCTEYPMPEMIGFITCQHEFCKQCVLNWLEETIVTKYPCKWNCPYCPDDDYLNVDKN 529
C +C + E + C H FC++C L+ TI + CP+ D +
Sbjct: 270 CPVCYSVLAPGEAVVLRECLHTFCREC----LQGTIRNSQEAEVACPFI--DSTYSCPGK 323
Query: 530 LHYGQLRGILSEKDNL------ISIFESKLLQEQLMKSPNFH-WCANEECTNGFEAEGIE 688
L ++R +LS +D +SI E++ K+P+ WC E+ N F
Sbjct: 324 LLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEF------ 377
Query: 689 KILCPSCKTPMCVKCNRKWQEAHENKSCQE 778
CP C C+ C + HE+ +C+E
Sbjct: 378 --TCPVCTRVNCLLC----KAIHEHMNCRE 401
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B
virus X-associated protein 4) (HBV-associated factor 4)
(RING finger protein 54)
Length = 500
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/172 (23%), Positives = 72/172 (41%), Gaps = 7/172 (4%)
Frame = +2
Query: 284 HLKQAITDQETIDGAINFLQKACELCCTEYPMPEMIGFITCQHEFCKQCVLNWLEETIVT 463
+L+ DQ ++ +N C +C + E + C H FC++C L+ TI
Sbjct: 252 YLQHVQLDQRSL--VLNTEPAECPVCYSVLAPGEAVVLRECLHTFCREC----LQGTIRN 305
Query: 464 KYPCKWNCPYCPDDDYLNVDKNLHYGQLRGILSEKDNL------ISIFESKLLQEQLMKS 625
+ +CP+ D+ + L +++ +L+ +D ISI E++ K+
Sbjct: 306 SQEAEVSCPFI--DNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKT 363
Query: 626 PNFH-WCANEECTNGFEAEGIEKILCPSCKTPMCVKCNRKWQEAHENKSCQE 778
P+ WC E+ N F CP C C+ C + HE +C+E
Sbjct: 364 PDCKGWCFFEDDVNEF--------TCPVCFHVNCLLC----KAIHEQMNCKE 403
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,981,064
Number of Sequences: 369166
Number of extensions: 1800819
Number of successful extensions: 5532
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5196
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5505
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7308943600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)