Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_L14
(791 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q10752|CDC28_SCHPO Putative ATP-dependent RNA helicase c... 145 9e-35
sp|Q9P774|PRP16_SCHPO Pre-mRNA splicing factor RNA helicase... 145 2e-34
sp|P45018|HRPA_HAEIN ATP-dependent helicase hrpA homolog 144 2e-34
sp|Q14562|DHX8_HUMAN ATP-dependent helicase DHX8 (RNA helic... 144 4e-34
sp|O42643|DHX8_SCHPO Putative pre-mRNA splicing factor ATP-... 143 5e-34
sp|Q9H6R0|DHX33_HUMAN Putative ATP-dependent helicase DHX33... 143 5e-34
sp|P43329|HRPA_ECOLI ATP-dependent helicase hrpA 143 5e-34
sp|Q9HDY4|YK16_SCHPO Putative ATP-dependent RNA helicase PB... 143 6e-34
sp|O35286|DHX15_MOUSE Putative pre-mRNA splicing factor RNA... 141 2e-33
sp|O43143|DHX15_HUMAN Putative pre-mRNA splicing factor RNA... 141 2e-33
>sp|Q10752|CDC28_SCHPO Putative ATP-dependent RNA helicase cdc28
Length = 1055
Score = 145 bits (367), Expect = 9e-35
Identities = 94/262 (35%), Positives = 141/262 (53%), Gaps = 9/262 (3%)
Frame = +1
Query: 31 GDILIFL--QTELKVRK------CRKVLKNLKRTRVLKFFANMDYDDKLRVFDDFSP-YR 183
GDIL+FL Q E+++ CR + K + + +AN+ + + ++FD P R
Sbjct: 628 GDILVFLTGQDEIELMSENMQELCRILGKRIPEIILCPIYANLPSELQAKIFDPTPPGAR 687
Query: 184 KIIIATNIAETSLTIPGVDFVIDSGAVKRISFDHETWVEKWVSTYISVTEADQRKGRTGR 363
K+++ATNIAETS+TI GV+FVIDSG VK+ ++ T +E VS S ADQR GR GR
Sbjct: 688 KVVLATNIAETSITIDGVNFVIDSGFVKQNMYNPRTGMESLVSVPCSRASADQRAGRAGR 747
Query: 364 TGPGCCYRLYEESFIKETDENEEDESIYDIKFPFYCQEKKESETNKRFHRFPLPEILQAN 543
GPG C+RLY + T NE D PEI + N
Sbjct: 748 VGPGKCFRLY----TRRTYNNELD-------------------------MVTSPEIQRTN 778
Query: 544 LGNMILILKSLGIDDIMRFPFIVYPNESHVKSAVDQLTKLSLLDRNTDLTKLGKRVSFLP 723
L N++L+LKSLGI++++ F F+ P + +++ L L L+ +LTKLG++++ P
Sbjct: 779 LTNIVLLLKSLGINNLLDFDFMDAPPPETLMRSLELLYALGALNNRGELTKLGRQMAEFP 838
Query: 724 LEPRLGKVVCMGSSFRCSRDVL 789
+P L K + S + C +VL
Sbjct: 839 TDPMLSKSLIASSKYGCVEEVL 860
>sp|Q9P774|PRP16_SCHPO Pre-mRNA splicing factor RNA helicase prp16
Length = 1173
Score = 145 bits (365), Expect = 2e-34
Identities = 85/262 (32%), Positives = 139/262 (53%), Gaps = 9/262 (3%)
Frame = +1
Query: 31 GDILIFLQTELKVRKCRKV-------LKNLKRTRVLKFFANMDYDDKLRVFDDFSP-YRK 186
GDIL+F+ + + ++ L + R +L ++ M D + ++FD P RK
Sbjct: 701 GDILVFMTGQEDIEATCEIIADRLNQLHDAPRLSILPIYSQMPADLQAKIFDSAEPGVRK 760
Query: 187 IIIATNIAETSLTIPGVDFVIDSGAVKRISFDHETWVEKWVSTYISVTEADQRKGRTGRT 366
+++ATNIAETSLT+ G+ +V+D+G K ++ + ++ T IS A+QR GR GRT
Sbjct: 761 VVVATNIAETSLTVHGISYVVDTGYCKLKMYNSKLGIDTLQVTPISQANANQRAGRAGRT 820
Query: 367 GPGCCYRLYEE-SFIKETDENEEDESIYDIKFPFYCQEKKESETNKRFHRFPLPEILQAN 543
GPG YRLY E ++I+E E LPEI + N
Sbjct: 821 GPGIAYRLYTEMAYIREMFET------------------------------TLPEIQRTN 850
Query: 544 LGNMILILKSLGIDDIMRFPFIVYPNESHVKSAVDQLTKLSLLDRNTDLTKLGKRVSFLP 723
L N +LILKSLG+++I F F+ P + +++ +L L LD LT LGK++S P
Sbjct: 851 LSNTVLILKSLGVEEISDFDFMDRPPNDTLMASLYELWTLGALDNFGKLTTLGKKMSLFP 910
Query: 724 LEPRLGKVVCMGSSFRCSRDVL 789
++P L K++ + ++C+ +++
Sbjct: 911 MDPSLSKLIIIAEDYKCTEEII 932
>sp|P45018|HRPA_HAEIN ATP-dependent helicase hrpA homolog
Length = 1304
Score = 144 bits (364), Expect = 2e-34
Identities = 88/263 (33%), Positives = 139/263 (52%), Gaps = 9/263 (3%)
Frame = +1
Query: 28 KGDILIFLQTELKVRKCRKVLK--NLKRTRVLKFFANMDYDDKLRVFDDFSPYRKIIIAT 201
+GDILIF+ E ++R + L+ NLK T +L FA + ++ ++F S +I++AT
Sbjct: 294 RGDILIFMNGEREIRDTAEALQKQNLKHTEILPLFARLSAQEQNKIFHP-SGLNRIVLAT 352
Query: 202 NIAETSLTIPGVDFVIDSGAVKRISFDHETWVEKWVSTYISVTEADQRKGRTGRTGPGCC 381
N+AETSLT+P + +VID G + + + T V++ IS A+QRKGR GR G C
Sbjct: 353 NVAETSLTVPSIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGIC 412
Query: 382 YRLYEESFIKETDENEEDESIYDIKFPFYCQEKKESETNKRFHRFPLPEILQANLGNMIL 561
RLY E D N E F PEIL+ NL ++IL
Sbjct: 413 IRLYSEE-----DFNSRPE-------------------------FTDPEILRTNLASVIL 442
Query: 562 ILKSLGIDDIMRFPFIVYPNESHVKSAVDQLTKLSLLD-------RNTDLTKLGKRVSFL 720
+ +LG+DDI FPF+ P+E H++ V L +L + LT++G++++ L
Sbjct: 443 QMTALGLDDIEAFPFVDAPDERHIQDGVKLLEELGAFETVQTKSGEKRLLTRVGRQLAQL 502
Query: 721 PLEPRLGKVVCMGSSFRCSRDVL 789
P++PRL K++ +F C +++
Sbjct: 503 PVDPRLAKMILSAVNFGCVYEMM 525
>sp|Q14562|DHX8_HUMAN ATP-dependent helicase DHX8 (RNA helicase HRH1) (DEAH-box protein 8)
Length = 1220
Score = 144 bits (362), Expect = 4e-34
Identities = 93/262 (35%), Positives = 145/262 (55%), Gaps = 9/262 (3%)
Frame = +1
Query: 31 GDILIFLQTELKVRKCRKVLKNLKRTR--------VLKFFANMDYDDKLRVFDDFSP-YR 183
GDIL+FL + ++ ++L ++ +L ++ + + + R+FD P R
Sbjct: 774 GDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSR 833
Query: 184 KIIIATNIAETSLTIPGVDFVIDSGAVKRISFDHETWVEKWVSTYISVTEADQRKGRTGR 363
K++IATNIAETSLTI G+ +V+D G VK+ ++ +T +++ V T IS +A QR GR GR
Sbjct: 834 KVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGR 893
Query: 364 TGPGCCYRLYEESFIKETDENEEDESIYDIKFPFYCQEKKESETNKRFHRFPLPEILQAN 543
TGPG CYRLY T+ DE + TN +PEI + N
Sbjct: 894 TGPGKCYRLY-------TERAYRDEML---------------TTN-------VPEIQRTN 924
Query: 544 LGNMILILKSLGIDDIMRFPFIVYPNESHVKSAVDQLTKLSLLDRNTDLTKLGKRVSFLP 723
L + +L LK++GI+D++ F F+ P + +A++QL L LD LT+LG+R++ P
Sbjct: 925 LASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFP 984
Query: 724 LEPRLGKVVCMGSSFRCSRDVL 789
LEP L K++ M CS ++L
Sbjct: 985 LEPMLCKMLIMSVHLGCSEEML 1006
>sp|O42643|DHX8_SCHPO Putative pre-mRNA splicing factor ATP-dependent RNA helicase
C10F6.02c
Length = 1168
Score = 143 bits (361), Expect = 5e-34
Identities = 92/262 (35%), Positives = 141/262 (53%), Gaps = 9/262 (3%)
Frame = +1
Query: 31 GDILIFL--------QTELKVRKCRKVLKNLKRTRVLKFFANMDYDDKLRVFDDFSPY-R 183
GDIL+FL E+ + + + ++ +L ++ + + + R+F+ P R
Sbjct: 720 GDILVFLTGQEEIDTSCEILYERSKMLGDSIPELVILPVYSALPSEIQSRIFEPAPPGGR 779
Query: 184 KIIIATNIAETSLTIPGVDFVIDSGAVKRISFDHETWVEKWVSTYISVTEADQRKGRTGR 363
K++IATNIAETSLTI G+ +V+D G VK+ FD + ++ + T IS +A QR GR GR
Sbjct: 780 KVVIATNIAETSLTIDGIYYVVDPGFVKQSCFDPKLGMDSLIVTPISQAQARQRSGRAGR 839
Query: 364 TGPGCCYRLYEESFIKETDENEEDESIYDIKFPFYCQEKKESETNKRFHRFPLPEILQAN 543
TGPG CYRLY ES + NE S P+PEI + N
Sbjct: 840 TGPGKCYRLYTESAYR----NEMLPS-------------------------PIPEIQRQN 870
Query: 544 LGNMILILKSLGIDDIMRFPFIVYPNESHVKSAVDQLTKLSLLDRNTDLTKLGKRVSFLP 723
L + IL+LK++GI+D++ F F+ P + +A+ L LS LD LT LG++++ P
Sbjct: 871 LSHTILMLKAMGINDLLNFDFMDPPPAQTMIAALQNLYALSALDDEGLLTPLGRKMADFP 930
Query: 724 LEPRLGKVVCMGSSFRCSRDVL 789
+EP+L KV+ CS ++L
Sbjct: 931 MEPQLSKVLITSVELGCSEEML 952
>sp|Q9H6R0|DHX33_HUMAN Putative ATP-dependent helicase DHX33 (DEAH-box protein 33)
Length = 707
Score = 143 bits (361), Expect = 5e-34
Identities = 88/264 (33%), Positives = 141/264 (53%), Gaps = 12/264 (4%)
Frame = +1
Query: 34 DILIFL----QTELKVRKCRKVLKNLK----RTRVLKFFANMDYDDKLRVFDDFSP-YRK 186
DIL+FL + E + CR + K+L VL +A++ Y +LRVF YRK
Sbjct: 290 DILVFLTGQEEIEAMSKTCRDIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRK 349
Query: 187 IIIATNIAETSLTIPGVDFVIDSGAVKRISFDHETWVEKWVSTYISVTEADQRKGRTGRT 366
+II+TNIAETS+TI G+ +V+D+G VK ++ ++ +E +S T+A QR GR GR
Sbjct: 350 VIISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGRE 409
Query: 367 GPGCCYRLYEESFIKETDENEEDESIYDIKFPFYCQEKKESETNKRFHRFPLPEILQANL 546
G CYRLY E DE E +F + +PEI + NL
Sbjct: 410 DSGICYRLYTE------DEFE------------------------KFDKMTVPEIQRCNL 439
Query: 547 GNMILILKSLGIDDIMRFPFIVYPNESHVKSAVDQLTKLSLLDRNTD---LTKLGKRVSF 717
+++L L ++ + +++ F F+ P+ H+++A+ QL L L+ D LT +G++++
Sbjct: 440 ASVMLQLLAMKVPNVLTFDFMSKPSPDHIQAAIAQLDLLGALEHKDDQLTLTPMGRKMAA 499
Query: 718 LPLEPRLGKVVCMGSSFRCSRDVL 789
PLEP+ K + M F C+ ++L
Sbjct: 500 FPLEPKFAKTILMSPKFHCTEEIL 523
>sp|P43329|HRPA_ECOLI ATP-dependent helicase hrpA
Length = 1300
Score = 143 bits (361), Expect = 5e-34
Identities = 89/267 (33%), Positives = 139/267 (52%), Gaps = 8/267 (2%)
Frame = +1
Query: 13 LSKTKKGDILIFLQTELKVRKCRKVLK--NLKRTRVLKFFANMDYDDKLRVFDDFSPYRK 186
LS+ GDILIF+ E ++R L NL+ T +L +A + ++ RVF S R+
Sbjct: 285 LSQESHGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNRVFQSHSG-RR 343
Query: 187 IIIATNIAETSLTIPGVDFVIDSGAVKRISFDHETWVEKWVSTYISVTEADQRKGRTGRT 366
I++ATN+AETSLT+PG+ +VID G + + + T V++ IS A+QRKGR GR
Sbjct: 344 IVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRV 403
Query: 367 GPGCCYRLY-EESFIKETDENEEDESIYDIKFPFYCQEKKESETNKRFHRFPLPEILQAN 543
G C RLY E+ F+ + F PEIL+ N
Sbjct: 404 SEGICIRLYSEDDFLSRPE-------------------------------FTDPEILRTN 432
Query: 544 LGNMILILKSLGIDDIMRFPFIVYPNESHVKSAVDQLTKLSLLDRNTD-----LTKLGKR 708
L ++IL + +LG+ DI FPF+ P++ +++ V L +L + + LT LG++
Sbjct: 433 LASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQ 492
Query: 709 VSFLPLEPRLGKVVCMGSSFRCSRDVL 789
+S LP++PRL ++V C R+ +
Sbjct: 493 LSQLPVDPRLARMVLEAQKHGCVREAM 519
>sp|Q9HDY4|YK16_SCHPO Putative ATP-dependent RNA helicase PB1A10.06c
Length = 1183
Score = 143 bits (360), Expect = 6e-34
Identities = 80/223 (35%), Positives = 125/223 (56%), Gaps = 2/223 (0%)
Frame = +1
Query: 112 VLKFFANMDYDDKLRVFDDFSP--YRKIIIATNIAETSLTIPGVDFVIDSGAVKRISFDH 285
VL ++ + +D+++VFD SP +R I+ATN+AETS+TIP + +V+D G K ++
Sbjct: 704 VLPLYSLLTTEDQMKVFDS-SPEGHRMCIVATNVAETSITIPNIRYVVDCGKAKERVYNE 762
Query: 286 ETWVEKWVSTYISVTEADQRKGRTGRTGPGCCYRLYEESFIKETDENEEDESIYDIKFPF 465
+T V+K+ +IS ADQR GR GRTGPG CYRLY +++D FP
Sbjct: 763 KTSVQKFEVRWISKANADQRAGRAGRTGPGHCYRLY-------------SSAVFDSSFPL 809
Query: 466 YCQEKKESETNKRFHRFPLPEILQANLGNMILILKSLGIDDIMRFPFIVYPNESHVKSAV 645
+ LPEIL+ + +++L +K++ ID+I FPF P S ++ ++
Sbjct: 810 H----------------SLPEILRTPVESIVLQMKNMNIDNIANFPFPTSPGRSRLEKSL 853
Query: 646 DQLTKLSLLDRNTDLTKLGKRVSFLPLEPRLGKVVCMGSSFRC 774
L+ L +D LTKLG+++S PL PR K++ +G C
Sbjct: 854 KLLSNLGAIDSEGVLTKLGEQMSLFPLSPRFSKMLIIGQQHGC 896
>sp|O35286|DHX15_MOUSE Putative pre-mRNA splicing factor RNA helicase (DEAH box protein 15)
Length = 795
Score = 141 bits (355), Expect = 2e-33
Identities = 90/274 (32%), Positives = 144/274 (52%), Gaps = 15/274 (5%)
Frame = +1
Query: 13 LSKTKKGDILIFLQTELKVRKCRKVLKN--------LKRTRVLKFFANMDYDDKLRVFDD 168
+ + ++GD+L+FL + ++ + K +K + +++ ++ + + R+F+
Sbjct: 344 MCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEP 403
Query: 169 FSPY-------RKIIIATNIAETSLTIPGVDFVIDSGAVKRISFDHETWVEKWVSTYISV 327
P RK++++TNIAETSLTI GV FVID G K+ ++ VE + T IS
Sbjct: 404 PPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISK 463
Query: 328 TEADQRKGRTGRTGPGCCYRLYEESFIKETDENEEDESIYDIKFPFYCQEKKESETNKRF 507
A QR GR GRT PG C+RLY E K E ++ Y
Sbjct: 464 ASAQQRAGRAGRTRPGKCFRLYTEKAYK----TEMQDNTY-------------------- 499
Query: 508 HRFPLPEILQANLGNMILILKSLGIDDIMRFPFIVYPNESHVKSAVDQLTKLSLLDRNTD 687
PEIL++NLG+++L LK LGIDD++ F F+ P + A++ L L+ L+ + D
Sbjct: 500 -----PEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGD 554
Query: 688 LTKLGKRVSFLPLEPRLGKVVCMGSSFRCSRDVL 789
LT+LG ++ PL+P+L K+V + CS +VL
Sbjct: 555 LTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVL 588
>sp|O43143|DHX15_HUMAN Putative pre-mRNA splicing factor RNA helicase (DEAH box protein 15)
(ATP-dependent RNA helicase #46)
Length = 795
Score = 141 bits (355), Expect = 2e-33
Identities = 90/274 (32%), Positives = 144/274 (52%), Gaps = 15/274 (5%)
Frame = +1
Query: 13 LSKTKKGDILIFLQTELKVRKCRKVLKN--------LKRTRVLKFFANMDYDDKLRVFDD 168
+ + ++GD+L+FL + ++ + K +K + +++ ++ + + R+F+
Sbjct: 344 MCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEP 403
Query: 169 FSPY-------RKIIIATNIAETSLTIPGVDFVIDSGAVKRISFDHETWVEKWVSTYISV 327
P RK++++TNIAETSLTI GV FVID G K+ ++ VE + T IS
Sbjct: 404 PPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISK 463
Query: 328 TEADQRKGRTGRTGPGCCYRLYEESFIKETDENEEDESIYDIKFPFYCQEKKESETNKRF 507
A QR GR GRT PG C+RLY E K E ++ Y
Sbjct: 464 ASAQQRAGRAGRTRPGKCFRLYTEKAYK----TEMQDNTY-------------------- 499
Query: 508 HRFPLPEILQANLGNMILILKSLGIDDIMRFPFIVYPNESHVKSAVDQLTKLSLLDRNTD 687
PEIL++NLG+++L LK LGIDD++ F F+ P + A++ L L+ L+ + D
Sbjct: 500 -----PEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGD 554
Query: 688 LTKLGKRVSFLPLEPRLGKVVCMGSSFRCSRDVL 789
LT+LG ++ PL+P+L K+V + CS +VL
Sbjct: 555 LTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVL 588
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,396,778
Number of Sequences: 369166
Number of extensions: 1621773
Number of successful extensions: 4931
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4717
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4895
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7425705210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)