Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_L07
(783 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q19673|TYR3_CAEEL Putative tyrosinase-like protein tyr-3... 125 1e-28
sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precurs... 66 9e-11
sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1) 66 1e-10
sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1) 66 1e-10
sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precurs... 65 2e-10
sp|P78504|JAG1_HUMAN Jagged-1 precursor (Jagged1) (hJ1) (CD... 64 5e-10
sp|Q9QW30|NOTC2_RAT Neurogenic locus notch homolog protein ... 62 2e-09
sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1... 60 5e-09
sp|Q6DI48|DLLA_BRARE Delta-like protein A precursor (DeltaA... 60 7e-09
sp|Q90Y54|JAG1B_BRARE Jagged-1b precursor (Jagged1b) (Jagged3) 60 9e-09
>sp|Q19673|TYR3_CAEEL Putative tyrosinase-like protein tyr-3 precursor
Length = 683
Score = 125 bits (314), Expect = 1e-28
Identities = 66/200 (33%), Positives = 88/200 (44%), Gaps = 35/200 (17%)
Frame = +2
Query: 131 CSDYNRNCTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWAD 310
C + N C W+ +G C+KN +M CK SC C N N C + H +C W+
Sbjct: 462 CFNENECCGPWSAKGECQKNPVYMNVWCKASCRQCTP---NYNINEECSDRHTNCAMWSR 518
Query: 311 RGECASNPGYMLVSCKKACNVCGKENK--------------------------------- 391
GEC NP +M +C+ +C CG+
Sbjct: 519 SGECNKNPLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTPCDS 578
Query: 392 --CADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASH 565
C + + CPI A+ G C S+P +M CK SCGVC + PC D + DCA WA
Sbjct: 579 PMCYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRPNYVYGPCADYHYDCAAWARRG 638
Query: 566 ECETNPSWMLYNCKKSCNHC 625
EC N WM NC++SCN C
Sbjct: 639 ECLKN-KWMPENCRRSCNTC 657
Score = 114 bits (284), Expect = 4e-25
Identities = 63/202 (31%), Positives = 85/202 (42%), Gaps = 36/202 (17%)
Frame = +2
Query: 269 NCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKE----NKCADYRKRCPIMAKYG 436
+C N +E C W+ +GEC NP YM V CK +C C +C+D C + ++ G
Sbjct: 461 SCFNENECCGPWSAKGECQKNPVYMNVWCKASCRQCTPNYNINEECSDRHTNCAMWSRSG 520
Query: 437 LCESDPSFMLQNCKESCGVCDGS---------------------------SKNRPC---- 523
C +P +M +NC+ SC C S +N PC
Sbjct: 521 ECNKNPLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTPCDSPM 580
Query: 524 -VDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYWAN 700
+ +Q C WA +C +NP +M CK SC CR + P C D C WA
Sbjct: 581 CYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRP---NYVYGP-CADYHYDCAAWAR 636
Query: 701 AGECQLNPGWAKQNCPFSCQHC 766
GEC N W +NC SC C
Sbjct: 637 RGECLKNK-WMPENCRRSCNTC 657
Score = 91.7 bits (226), Expect = 2e-18
Identities = 58/205 (28%), Positives = 77/205 (37%), Gaps = 75/205 (36%)
Frame = +2
Query: 8 NCIDRDRNCQMWSDRGECGINPEAMLVTCKKTCNQCGNPG-----KCSDYNRNCTKWARE 172
+C + + C WS +GEC NP M V CK +C QC P +CSD + NC W+R
Sbjct: 461 SCFNENECCGPWSAKGECQKNPVYMNVWCKASCRQC-TPNYNINEECSDRHTNCAMWSRS 519
Query: 173 GLCEKNFNFMQKNCKFSCDACQDI-------GDGDNS---------------------NP 268
G C KN +M +NC+ SC C G G +S +P
Sbjct: 520 GECNKNPLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTPCDSP 579
Query: 269 NCLNSHESCDTWADRGECASNPGYMLVSCK------------------------------ 358
C N + C WA RG+C SNPGYM CK
Sbjct: 580 MCYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRPNYVYGPCADYHYDCAAWARRGE 639
Query: 359 ------------KACNVCGKENKCA 397
++CN C + + A
Sbjct: 640 CLKNKWMPENCRRSCNTCVNQQQLA 664
Score = 86.7 bits (213), Expect = 7e-17
Identities = 54/171 (31%), Positives = 70/171 (40%), Gaps = 35/171 (20%)
Frame = +2
Query: 374 CGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSK-NRPCVDANQDCAG 550
C EN+C C + G C+ +P +M CK SC C + N C D + +CA
Sbjct: 462 CFNENEC------CGPWSAKGECQKNPVYMNVWCKASCRQCTPNYNINEECSDRHTNCAM 515
Query: 551 WAASHECETNPSWMLYNCKKSCNHCRDAR---------LESISNPN-------------- 661
W+ S EC NP WM NC+ SC C +R +SISNP
Sbjct: 516 WSRSGECNKNPLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTP 575
Query: 662 -----CKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC------GGCRD 781
C + C WA G+C+ NPG+ C SC C G C D
Sbjct: 576 CDSPMCYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRPNYVYGPCAD 626
Score = 75.5 bits (184), Expect = 2e-13
Identities = 34/81 (41%), Positives = 47/81 (58%), Gaps = 4/81 (4%)
Frame = +2
Query: 5 PNCIDRDRNCQMWSDRGECGINPEAMLVTCKKTCNQCGNP----GKCSDYNRNCTKWARE 172
P C + D+ C +W+ RG+C NP M CK +C C P G C+DY+ +C WAR
Sbjct: 579 PMCYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVC-RPNYVYGPCADYHYDCAAWARR 637
Query: 173 GLCEKNFNFMQKNCKFSCDAC 235
G C KN +M +NC+ SC+ C
Sbjct: 638 GECLKN-KWMPENCRRSCNTC 657
>sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precursor (Nematode astacin 15)
Length = 571
Score = 66.2 bits (160), Expect = 9e-11
Identities = 52/225 (23%), Positives = 86/225 (38%), Gaps = 10/225 (4%)
Frame = +2
Query: 122 PGKCSDYNRNCTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDT 301
P +C + +C A++G C +N +M+ NC SC C I + P + ++ T
Sbjct: 351 PSECRNLRGDCDDLAKQGWCIRNPGWMRANCPISCGMC--IPTKETQKPYVQTTTQAATT 408
Query: 302 WADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKE 481
A + + P L ++ C D R C ++ C+ +FM C +
Sbjct: 409 TARPQKPVTQPIQPLPPVPPLPPTTPED--CEDLRVDCLVLVSQRYCKISQNFMKSYCAK 466
Query: 482 SCGVC-----DGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLES 646
SCG C NRP V + + +P+ + K+
Sbjct: 467 SCGFCFKPPPTEIPDNRPTVVTTRPLVTLPPAVIRSRSPAPPVSTTTKAAPTTSTTSAAP 526
Query: 647 IS----NPNCKDLQIHCLYWANAGECQ-LNPGWAKQNCPFSCQHC 766
S C D + C +W +AG C+ + + K+NCP SC C
Sbjct: 527 YSPTPLPSECSDRKHFCSHWKSAGFCEGIFMNYMKKNCPASCGLC 571
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 2/131 (1%)
Frame = +2
Query: 380 KENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSK-NRPCVDANQDCAGWA 556
K ++C + R C +AK G C +P +M NC SCG+C + + +P V A
Sbjct: 350 KPSECRNLRGDCDDLAKQGWCIRNPGWMRANCPISCGMCIPTKETQKPYVQTTTQAATTT 409
Query: 557 A-SHECETNPSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYWANAGECQLNPGWA 733
A + T P L L + +C+DL++ CL + C+++ +
Sbjct: 410 ARPQKPVTQPIQPLPPVPP---------LPPTTPEDCEDLRVDCLVLVSQRYCKISQNFM 460
Query: 734 KQNCPFSCQHC 766
K C SC C
Sbjct: 461 KSYCAKSCGFC 471
>sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1)
Length = 1218
Score = 65.9 bits (159), Expect = 1e-10
Identities = 52/225 (23%), Positives = 84/225 (37%)
Frame = +2
Query: 92 CKKTCNQCGNPGKCSDYNRNCTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPN 271
C K N CG C + + C + NC+ + AC S+P
Sbjct: 293 CDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACL-------SDP- 344
Query: 272 CLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 451
++ SC + EC +PG+ +C + C N + C + C
Sbjct: 345 -CHNRGSCKETSSGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCP 401
Query: 452 PSFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 631
P + + C+ C+ +PCV+A + C AS+ C+ P WM NC + N C
Sbjct: 402 PQWTGKTCQLDANECEA----KPCVNA-RSCKNLIASYYCDCLPGWMGQNCDININDCLG 456
Query: 632 ARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC 766
+ ++ +C+DL N C PG+A +C C
Sbjct: 457 ---QCQNDASCRDL-------VNGYRCICPPGYAGDHCERDIDEC 491
Score = 53.5 bits (127), Expect = 6e-07
Identities = 53/231 (22%), Positives = 83/231 (35%), Gaps = 8/231 (3%)
Frame = +2
Query: 113 CGNPGKCSDYNRNC-TKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHE 289
C P +C C T W + LC+K+ N+ ++ CLN
Sbjct: 276 CNEPWQCL-----CETNWGGQ-LCDKDLNYC------------------GTHQPCLNRGT 311
Query: 290 SCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQ 469
+T D+ +C+ GY +C+ A + C + C + R C + CE P +
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHAC-LSDPCHN-RGSCKETSSGFECECSPGWTGP 369
Query: 470 NCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESI 649
C + C ++ + C +C P W C+ N C +
Sbjct: 370 TCSTNIDDCSPNNCSH-----GGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--PCV 422
Query: 650 SNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFS-------CQHCGGCRD 781
+ +CK+L I Y C PGW QNC + CQ+ CRD
Sbjct: 423 NARSCKNL-IASYY------CDCLPGWMGQNCDININDCLGQCQNDASCRD 466
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/226 (20%), Positives = 77/226 (34%), Gaps = 9/226 (3%)
Frame = +2
Query: 5 PNCIDRDRNCQMWSDRGECGINPEAMLVTCKKTCNQCGNPGKCSDYNRNCTKWAREGLCE 184
PN CQ + +C P+ TC+ N+C K R+C C+
Sbjct: 380 PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANEC--EAKPCVNARSCKNLIASYYCD 437
Query: 185 KNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKA 364
+M +NC + + C D S + +N + C PGY C++
Sbjct: 438 CLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR----------CICPPGYAGDHCERD 487
Query: 365 CNVCGK---------ENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNR 517
+ C +N+ ++ CP LC+ D + N
Sbjct: 488 IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN--------------- 532
Query: 518 PCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISN 655
PC + Q C A+ + C+ + NC +HCR E I +
Sbjct: 533 PCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCRTTTCEVIDS 577
Score = 42.4 bits (98), Expect = 0.001
Identities = 52/238 (21%), Positives = 79/238 (33%), Gaps = 13/238 (5%)
Frame = +2
Query: 107 NQCGNPGKCSDYNRNCTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSH 286
N C N +C YNR A + C+ ++ KNC D C+
Sbjct: 532 NPCQNGAQC--YNR-----ASDYFCKCPEDYEGKNCSHLKDHCRT---------TTCEVI 575
Query: 287 ESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPSFML 466
+SC + Y+ + NVCG KC K+ C+ + F
Sbjct: 576 DSCTVAMASNDTPEGVRYI------SSNVCGPHGKCKSQSG-----GKF-TCDCNKGFTG 623
Query: 467 QNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLES 646
C E+ C+ + PC + C S++C + W +C+ + N C
Sbjct: 624 TYCHENINDCESN----PCKNGGT-CIDGVNSYKCICSDGWEGAHCENNINDCS------ 672
Query: 647 ISNP-----NCKDLQIHCLYWANAGECQLNPGWAKQNC--------PFSCQHCGGCRD 781
NP C+DL N C GW + C +C + G C D
Sbjct: 673 -QNPCHYGGTCRDL-------VNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYD 722
>sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1)
Length = 1219
Score = 65.9 bits (159), Expect = 1e-10
Identities = 52/225 (23%), Positives = 84/225 (37%)
Frame = +2
Query: 92 CKKTCNQCGNPGKCSDYNRNCTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPN 271
C K N CG C + + C + NC+ + AC S+P
Sbjct: 293 CDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACL-------SDP- 344
Query: 272 CLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 451
++ SC + EC +PG+ +C + C N + C + C
Sbjct: 345 -CHNRGSCKETSSGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCP 401
Query: 452 PSFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 631
P + + C+ C+ +PCV+A + C AS+ C+ P WM NC + N C
Sbjct: 402 PQWTGKTCQLDANECEA----KPCVNA-RSCKNLIASYYCDCLPGWMGQNCDININDCLG 456
Query: 632 ARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC 766
+ ++ +C+DL N C PG+A +C C
Sbjct: 457 ---QCQNDASCRDL-------VNGYRCICPPGYAGDHCERDIDEC 491
Score = 53.5 bits (127), Expect = 6e-07
Identities = 53/231 (22%), Positives = 83/231 (35%), Gaps = 8/231 (3%)
Frame = +2
Query: 113 CGNPGKCSDYNRNC-TKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHE 289
C P +C C T W + LC+K+ N+ ++ CLN
Sbjct: 276 CNEPWQCL-----CETNWGGQ-LCDKDLNYC------------------GTHQPCLNRGT 311
Query: 290 SCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQ 469
+T D+ +C+ GY +C+ A + C + C + R C + CE P +
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHAC-LSDPCHN-RGSCKETSSGFECECSPGWTGP 369
Query: 470 NCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESI 649
C + C ++ + C +C P W C+ N C +
Sbjct: 370 TCSTNIDDCSPNNCSH-----GGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--PCV 422
Query: 650 SNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFS-------CQHCGGCRD 781
+ +CK+L I Y C PGW QNC + CQ+ CRD
Sbjct: 423 NARSCKNL-IASYY------CDCLPGWMGQNCDININDCLGQCQNDASCRD 466
Score = 47.0 bits (110), Expect = 6e-05
Identities = 63/292 (21%), Positives = 101/292 (34%), Gaps = 32/292 (10%)
Frame = +2
Query: 2 DPNCIDRDRNCQMWSDRGECGINPEAMLVTCKKTCNQCGNPGKC-SDYNRN---CTKWAR 169
D +C D + G G + E + C N C N G C ++ NR C
Sbjct: 461 DASCRDLVNGYRCICPPGYAGDHCERDIDECAS--NPCLNGGHCQNEINRFQCLCPTGFS 518
Query: 170 EGLCEKNFNFMQKN-CKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYML 346
LC+ + ++ + N C+ + Q + C +E + + C + P ++
Sbjct: 519 GNLCQLDIDYCEPNPCQ---NGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVI 575
Query: 347 VSCKKAC--------------NVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKES 484
SC A NVCG KC + K+ C+ + F C E+
Sbjct: 576 DSCTVAMASNDTPEGVRYISSNVCGPHGKC-----KSESGGKF-TCDCNKGFTGTYCHEN 629
Query: 485 CGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISNP-- 658
C+G+ PC + C S++C + W +C+ + N C NP
Sbjct: 630 INDCEGN----PCTNGGT-CIDGVNSYKCICSDGWEGAHCENNINDCS-------QNPCH 677
Query: 659 ---NCKDLQIHCLYWANAGECQLNPGWAKQNC--------PFSCQHCGGCRD 781
C+DL N C GW + C +C + G C D
Sbjct: 678 YGGTCRDL-------VNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYD 722
Score = 44.7 bits (104), Expect = 3e-04
Identities = 47/226 (20%), Positives = 77/226 (34%), Gaps = 9/226 (3%)
Frame = +2
Query: 5 PNCIDRDRNCQMWSDRGECGINPEAMLVTCKKTCNQCGNPGKCSDYNRNCTKWAREGLCE 184
PN CQ + +C P+ TC+ N+C K R+C C+
Sbjct: 380 PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANEC--EAKPCVNARSCKNLIASYYCD 437
Query: 185 KNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKA 364
+M +NC + + C D S + +N + C PGY C++
Sbjct: 438 CLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR----------CICPPGYAGDHCERD 487
Query: 365 CNVCGK---------ENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNR 517
+ C +N+ ++ CP LC+ D + N
Sbjct: 488 IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN--------------- 532
Query: 518 PCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISN 655
PC + Q C A+ + C+ + NC +HCR E I +
Sbjct: 533 PCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDS 577
>sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precursor (Nematode astacin 13)
Length = 527
Score = 65.1 bits (157), Expect = 2e-10
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Frame = +2
Query: 389 KCADYRKRCPIMAKYGLCESDPS--FMLQNCKESCGVCDGSSKNRP-CVDANQDCAGWAA 559
KC D RK C +A+ G CES S FM +NC SCG C K + C DA C WA
Sbjct: 444 KCEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWAN 503
Query: 560 SHECETN--PSWMLYNCKKSCNHC 625
S C +M C KSCN C
Sbjct: 504 SGMCNQTVFKDYMRQKCAKSCNFC 527
Score = 58.2 bits (139), Expect = 3e-08
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Frame = +2
Query: 125 GKCSDYNRNCTKWAREGLCEKNFN--FMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCD 298
GKC D ++C AR G CE F+ FM +NC SC C I + + C ++ C+
Sbjct: 443 GKCEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKC--IAE-EKRKEVCEDARTWCE 499
Query: 299 TWADRGECASN--PGYMLVSCKKACNVC 376
WA+ G C YM C K+CN C
Sbjct: 500 RWANSGMCNQTVFKDYMRQKCAKSCNFC 527
Score = 47.8 bits (112), Expect = 3e-05
Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +2
Query: 521 CVDANQDCAGWAASHECETNPS--WMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYW 694
C D +DC A + CE+ S +M NC SC C E C+D + C W
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCI---AEEKRKEVCEDARTWCERW 501
Query: 695 ANAGECQ--LNPGWAKQNCPFSCQHC 766
AN+G C + + +Q C SC C
Sbjct: 502 ANSGMCNQTVFKDYMRQKCAKSCNFC 527
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 8/83 (9%)
Frame = +2
Query: 272 CLNSHESCDTWADRGECASNPG--YMLVSCKKACNVCGKENK----CADYRKRCPIMAKY 433
C + + C+ A G C S +M +C +C C E K C D R C A
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWANS 504
Query: 434 GLCESD--PSFMLQNCKESCGVC 496
G+C +M Q C +SC C
Sbjct: 505 GMCNQTVFKDYMRQKCAKSCNFC 527
>sp|P78504|JAG1_HUMAN Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen)
Length = 1218
Score = 63.9 bits (154), Expect = 5e-10
Identities = 52/225 (23%), Positives = 84/225 (37%)
Frame = +2
Query: 92 CKKTCNQCGNPGKCSDYNRNCTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPN 271
C K N CG C + + C + NC+ + AC S+P
Sbjct: 293 CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACL-------SDP- 344
Query: 272 CLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 451
++ SC + EC +PG+ +C + C N + C + C
Sbjct: 345 -CHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCP 401
Query: 452 PSFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 631
P + + C+ C+ +PCV+A + C AS+ C+ P WM NC + N C
Sbjct: 402 PQWTGKTCQLDANECEA----KPCVNA-KSCKNLIASYYCDCLPGWMGQNCDININDCLG 456
Query: 632 ARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC 766
+ ++ +C+DL N C PG+A +C C
Sbjct: 457 ---QCQNDASCRDL-------VNGYRCICPPGYAGDHCERDIDEC 491
Score = 53.5 bits (127), Expect = 6e-07
Identities = 53/231 (22%), Positives = 83/231 (35%), Gaps = 8/231 (3%)
Frame = +2
Query: 113 CGNPGKCSDYNRNC-TKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHE 289
C P +C C T W + LC+K+ N+ ++ CLN
Sbjct: 276 CNEPWQCL-----CETNWGGQ-LCDKDLNYC------------------GTHQPCLNGGT 311
Query: 290 SCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQ 469
+T D+ +C+ GY +C+ A + C + C + R C + CE P +
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHAC-LSDPCHN-RGSCKETSLGFECECSPGWTGP 369
Query: 470 NCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESI 649
C + C ++ + C +C P W C+ N C +
Sbjct: 370 TCSTNIDDCSPNNCSH-----GGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK--PCV 422
Query: 650 SNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFS-------CQHCGGCRD 781
+ +CK+L I Y C PGW QNC + CQ+ CRD
Sbjct: 423 NAKSCKNL-IASYY------CDCLPGWMGQNCDININDCLGQCQNDASCRD 466
Score = 43.5 bits (101), Expect = 7e-04
Identities = 46/226 (20%), Positives = 77/226 (34%), Gaps = 9/226 (3%)
Frame = +2
Query: 5 PNCIDRDRNCQMWSDRGECGINPEAMLVTCKKTCNQCGNPGKCSDYNRNCTKWAREGLCE 184
PN CQ + +C P+ TC+ N+C K ++C C+
Sbjct: 380 PNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANEC--EAKPCVNAKSCKNLIASYYCD 437
Query: 185 KNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKA 364
+M +NC + + C D S + +N + C PGY C++
Sbjct: 438 CLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR----------CICPPGYAGDHCERD 487
Query: 365 CNVCGK---------ENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNR 517
+ C +N+ ++ CP LC+ D + N
Sbjct: 488 IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN--------------- 532
Query: 518 PCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISN 655
PC + Q C A+ + C+ + NC +HCR E I +
Sbjct: 533 PCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDS 577
>sp|Q9QW30|NOTC2_RAT Neurogenic locus notch homolog protein 2 precursor (Notch 2)
[Contains: Notch 2 extracellular truncation; Notch 2
intracellular domain]
Length = 2471
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/263 (25%), Positives = 95/263 (36%), Gaps = 18/263 (6%)
Frame = +2
Query: 32 CQMWSDRGECGINPEAMLVTCKKTCNQCG-----NPGKCSD----YNRNCTKWAREGLCE 184
CQ D C NP M C ++C N G+C D Y NC GL
Sbjct: 584 CQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQP-GTSGL-- 640
Query: 185 KNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSC--- 355
NC+ + D C SNP CL H +C +R C +PG+ C
Sbjct: 641 --------NCEINFDDCA-------SNP-CL--HGACVDGINRYSCVCSPGFTGQRCNID 682
Query: 356 --KKACNVCGKENKCAD----YRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNR 517
+ A N C K+ C + +R CP + C S + C S
Sbjct: 683 IDECASNPCRKDATCINDVNGFRCMCPEGPHHPSCYSQ----VNECLSS----------- 727
Query: 518 PCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYWA 697
PC+ N C G + ++C + W+ NC+ N C +SNP C++ C
Sbjct: 728 PCIHGN--CTGGLSGYKCLCDAGWVGINCEVDKNEC-------LSNP-CQNGGT-CNNLV 776
Query: 698 NAGECQLNPGWAKQNCPFSCQHC 766
N C G+ NC + C
Sbjct: 777 NGYRCTCKKGFKGYNCQVNIDEC 799
Score = 49.3 bits (116), Expect = 1e-05
Identities = 65/257 (25%), Positives = 91/257 (35%), Gaps = 4/257 (1%)
Frame = +2
Query: 8 NCIDRDRNCQMWSDRGECGINPEAMLVTCKKTCNQCGNPGKCSDY--NRNCTKWAREGLC 181
NC + D G GIN E C N C N G C++ CT C
Sbjct: 733 NCTGGLSGYKCLCDAGWVGINCEVDKNECLS--NPCQNGGTCNNLVNGYRCT-------C 783
Query: 182 EKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKK 361
+K F NC+ + D C SNP CLN D + C Y +C+
Sbjct: 784 KKGFKGY--NCQVNIDECA-------SNP-CLNQGTCLDDVSGY-TCHCMLPYTGKNCQT 832
Query: 362 ACNVCGKENKC--ADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNRPCVDAN 535
C N C A K P + C P + Q C C ++PC++ N
Sbjct: 833 VLAPCSP-NPCENAAVCKEAPNFESF-TCLCAPGWQGQRCTVDVDEC----VSKPCMN-N 885
Query: 536 QDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYWANAGECQ 715
C S+ CE P + +C++ N C ++NP C++ C+ N C
Sbjct: 886 GICHNTQGSYMCECPPGFSGMDCEEDINDC-------LANP-CQN-GGSCVDKVNTFSCL 936
Query: 716 LNPGWAKQNCPFSCQHC 766
PG+ C C
Sbjct: 937 CLPGFVGDKCQTDMNEC 953
Score = 46.2 bits (108), Expect = 1e-04
Identities = 57/256 (22%), Positives = 79/256 (30%), Gaps = 4/256 (1%)
Frame = +2
Query: 11 CIDRDRNCQMWSDRGECGINPEAMLVTCKKTCNQCGNPGKCSD----YNRNCTKWAREGL 178
C+D+ Q G G + + C T C N KC D Y C L
Sbjct: 509 CVDKVNRFQCLCPPGFTGPVCQIDIDDCSST--PCLNGAKCIDHPNGYECQCATGFTGTL 566
Query: 179 CEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCK 358
C++N DN +P+ + H C D C NPGYM C
Sbjct: 567 CDENI--------------------DNCDPDPCH-HGQCQDGIDSYTCICNPGYMGAICS 605
Query: 359 KACNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNRPCVDANQ 538
+ C D RC + C P NC+ + C + PC+ +
Sbjct: 606 DQIDECYSSPCLND--GRCIDLVNGYQCNCQPGTSGLNCEINFDDC----ASNPCL--HG 657
Query: 539 DCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYWANAGECQL 718
C + C +P + C + C SNP KD C+ N C
Sbjct: 658 ACVDGINRYSCVCSPGFTGQRCNIDIDEC-------ASNPCRKDAT--CINDVNGFRCMC 708
Query: 719 NPGWAKQNCPFSCQHC 766
G +C C
Sbjct: 709 PEGPHHPSCYSQVNEC 724
Score = 45.4 bits (106), Expect = 2e-04
Identities = 63/251 (25%), Positives = 81/251 (32%), Gaps = 28/251 (11%)
Frame = +2
Query: 113 CGNPGKCSDYNRNCTKWAREGL----CEKNFNFMQKNCKFSCDACQDIGDGDNS------ 262
C N G CSDY + T G CE N + ++ F+ C DG NS
Sbjct: 958 CKNGGTCSDYVNSYTCTCPAGFHGVHCENNIDECTESSCFNGGTCV---DGINSFSCLCP 1014
Query: 263 ----NPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCAD----YRKRCP 418
P CL+ D EC+SNP C C D YR CP
Sbjct: 1015 VGFTGPFCLH---------DINECSSNP-------------CLNSGTCVDGLGTYRCTCP 1052
Query: 419 IMAKYGLCESDPSFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLY 598
+ + +NC+ +C S PC + CA A C P W
Sbjct: 1053 L-----------GYTGKNCQTLVNLCSPS----PCKNKG-TCAQEKARPRCLCPPGWDGA 1096
Query: 599 NCKKSCNHCRDARLES--ISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFS------ 754
C C+ A L+ C+ I C+ N CQ G+ C
Sbjct: 1097 YCDVLNVSCKAAALQKGVPVEHLCQHSGI-CINAGNTHHCQCPLGYTGSYCEEQLDECAS 1155
Query: 755 --CQHCGGCRD 781
CQH C D
Sbjct: 1156 NPCQHGATCSD 1166
Score = 39.7 bits (91), Expect = 0.009
Identities = 51/235 (21%), Positives = 78/235 (33%), Gaps = 13/235 (5%)
Frame = +2
Query: 107 NQCGNPGKCSDYNRNCTKWAREGL----CEKNFNFMQKNCKFSCDACQDIGDGDNSNPNC 274
N C N G C D GL C + KNC+ + C +P+
Sbjct: 1032 NPCLNSGTCVD-----------GLGTYRCTCPLGYTGKNCQTLVNLC---------SPSP 1071
Query: 275 LNSHESCDTWADRGECASNPGY-------MLVSCKKACNVCGK--ENKCADYRKRCPIMA 427
+ +C R C PG+ + VSCK A G E+ C + C
Sbjct: 1072 CKNKGTCAQEKARPRCLCPPGWDGAYCDVLNVSCKAAALQKGVPVEHLC-QHSGICINAG 1130
Query: 428 KYGLCESDPSFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCK 607
C+ + C+E C + PC C+ + + CE P + NC+
Sbjct: 1131 NTHHCQCPLGYTGSYCEEQLDEC----ASNPC-QHGATCSDFIGGYRCECVPGYQGVNCE 1185
Query: 608 KSCNHCRDARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCGG 772
+ C++ + + C DL N +C PG C + C G
Sbjct: 1186 YEVDECQNQPCQ--NGGTCIDL-------VNHFKCSCPPGTRGLLCEENIDDCAG 1231
Score = 38.1 bits (87), Expect = 0.027
Identities = 38/175 (21%), Positives = 60/175 (34%), Gaps = 12/175 (6%)
Frame = +2
Query: 92 CKKTCNQCGNPGKCSDYNRNCTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPN 271
C N+C PG+C + C C+ F ++C C +
Sbjct: 179 CDADINECDIPGRC-QHGGTCLNLPGSYRCQCPQRFTGQHCDSPYVPC--------APSP 229
Query: 272 CLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCAD----------YRKRCPI 421
C+N T EC PG+ +C++ + C +KC + Y RCP
Sbjct: 230 CVNGGTCRQTGDFTSECHCLPGFEGSNCERNIDDC-PNHKCQNGGVCVDGVNTYNCRCPP 288
Query: 422 MAKYGLC--ESDPSFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETN 580
C + D + N ++ G C + CV N GW+ +C N
Sbjct: 289 QWTGQFCTEDVDECLLQPNACQNGGTCTNRNGGYGCVCVN----GWSGD-DCSEN 338
Score = 35.4 bits (80), Expect = 0.18
Identities = 56/267 (20%), Positives = 92/267 (34%), Gaps = 47/267 (17%)
Frame = +2
Query: 53 GECGINPEAMLVTCKKTCNQCGNPGKCSD----YNRNCTKWAREGLCEKNFNFMQK---- 208
G G+N E + C+ C N G C D + +C R LCE+N +
Sbjct: 1178 GYQGVNCEYEVDECQN--QPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCAGAPHC 1235
Query: 209 -------------NCK----FSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPG 337
+C+ F+ + C+ + SNP C + +C
Sbjct: 1236 LNGGQCVDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLKNNYQCVCRSA 1295
Query: 338 YMLVSCKKACNVCGKENKCADYRKRCPIMAKYG---LCESDPSFMLQNCKESCG------ 490
+ C+ +VC + C + C + + +C P F C+ SCG
Sbjct: 1296 FTGRHCETFLDVC-PQKPCLN-GGTCAVASNVPDGFICRCPPGFSGARCQSSCGQVKCRR 1353
Query: 491 --VCDGSSKNRPCVDAN-QDCAGWAASHECETNPSWM------LYNCKKS----CNHCRD 631
C ++ C N +DC AS+ C+ + Y+C+ S +HC +
Sbjct: 1354 GEQCVHTASGPHCFCPNHKDCESGCASNPCQHGGTCYPQRQPPYYSCRCSPPFWGSHC-E 1412
Query: 632 ARLESISNPNCKDLQIHCLYWANAGEC 712
+ S P L +C A G C
Sbjct: 1413 SYTAPTSTPPATCLSQYCADKARDGIC 1439
>sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1 precursor
Length = 601
Score = 60.5 bits (145), Expect = 5e-09
Identities = 23/81 (28%), Positives = 40/81 (49%)
Frame = +2
Query: 383 ENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAAS 562
++ C + C ++ C ++ +M + C++SCG+C + NR C D + CA W
Sbjct: 477 QSNCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQ 536
Query: 563 HECETNPSWMLYNCKKSCNHC 625
+ C WM NC+ +C C
Sbjct: 537 NFCTRRRQWMAENCQATCGWC 557
Score = 60.1 bits (144), Expect = 7e-09
Identities = 26/82 (31%), Positives = 37/82 (45%)
Frame = +2
Query: 521 CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYWAN 700
C + + C W+ +EC TN +M C+KSC C+ + +N C D I C YW
Sbjct: 480 CYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQS----NDNNRGCHDRHISCAYWRG 535
Query: 701 AGECQLNPGWAKQNCPFSCQHC 766
C W +NC +C C
Sbjct: 536 QNFCTRRRQWMAENCQATCGWC 557
Score = 57.0 bits (136), Expect = 6e-08
Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Frame = +2
Query: 8 NCIDRDRNCQMWSDRGECGINPEAMLVTCKKTCNQC---GNPGKCSDYNRNCTKWAREGL 178
NC + D C WS + EC N M C+K+C C N C D + +C W +
Sbjct: 479 NCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNF 538
Query: 179 CEKNFNFMQKNCKFSCDAC 235
C + +M +NC+ +C C
Sbjct: 539 CTRRRQWMAENCQATCGWC 557
Score = 56.6 bits (135), Expect = 7e-08
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +2
Query: 269 NCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENK---CADYRKRCPIMAKYGL 439
NC N C+ W+ + EC +N YM C+K+C +C + C D C
Sbjct: 479 NCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNF 538
Query: 440 CESDPSFMLQNCKESCGVCD 499
C +M +NC+ +CG C+
Sbjct: 539 CTRRRQWMAENCQATCGWCN 558
Score = 56.2 bits (134), Expect = 1e-07
Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 5/112 (4%)
Frame = +2
Query: 131 CSDYNRNCTKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWAD 310
C + + C +W+R+ C N +M + C+ SC CQ +++N C + H SC W
Sbjct: 480 CYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQ----SNDNNRGCHDRHISCAYWRG 535
Query: 311 RGECASNPGYMLVSCKKACNVCGKEN-----KCADYRKRCPIMAKYGLCESD 451
+ C +M +C+ C C A +R AK+ L E D
Sbjct: 536 QNFCTRRRQWMAENCQATCGWCNMNEAQLCASVARQSRRVRRNAKFWLTEPD 587
>sp|Q6DI48|DLLA_BRARE Delta-like protein A precursor (DeltaA protein)
Length = 772
Score = 60.1 bits (144), Expect = 7e-09
Identities = 60/251 (23%), Positives = 94/251 (37%), Gaps = 21/251 (8%)
Frame = +2
Query: 92 CKKTCNQCGNPGKCS-------DYNRNCTKW--AREGLCEKNFNFMQKNCKFSCDAC--- 235
C + C PG+C Y C ++ G C++ + Q NC+
Sbjct: 232 CDEEHGFCEKPGECKCRVGFKGRYCDECIRYPGCLHGTCQQPW---QCNCQEGWGGLFCN 288
Query: 236 QDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRC 415
QD+ + P CLN +T C+ PG+ SC+ N C N C + C
Sbjct: 289 QDLNYCTHHKP-CLNGATCSNTGQGSYTCSCRPGFSGASCEIEVNEC-TGNPCRN-GGSC 345
Query: 416 PIMAKYGLCESDPSFMLQNCKESCGVC-DGSSKNRPCVDANQDCAGWAASHECETNPSWM 592
M C P F +NC+ S C DG PC + + + C+ +
Sbjct: 346 TDMENTYSCTCPPGFYGKNCELSAMTCADG-----PCFNGGRCADNPDGGYFCQCPTGYA 400
Query: 593 LYNCKKSCNHCRDARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCP-------- 748
+NC+K +HC S+ C + C+ N+ CQ G+ NC
Sbjct: 401 GFNCEKKIDHC--------SSSPCSN-GARCVDLVNSYLCQCPDGFTGMNCDRAGDECSM 451
Query: 749 FSCQHCGGCRD 781
+ CQ+ G C++
Sbjct: 452 YPCQNGGTCQE 462
>sp|Q90Y54|JAG1B_BRARE Jagged-1b precursor (Jagged1b) (Jagged3)
Length = 1213
Score = 59.7 bits (143), Expect = 9e-09
Identities = 56/250 (22%), Positives = 90/250 (36%), Gaps = 41/250 (16%)
Frame = +2
Query: 155 TKWAREGLCEKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNP 334
T W + LC+K+ N+ ++ CLN +T D+ +C+
Sbjct: 283 TNWGGQ-LCDKDLNYC------------------GTHQPCLNGGTCSNTGPDKYQCSCED 323
Query: 335 GYMLVSCKKACNVCGKENKCAD----------YRKRCPIMAKYGLCESDPSFMLQN-CK- 478
GY V+C++A + C N CA+ Y C I CE + N CK
Sbjct: 324 GYSGVNCERAEHAC-LSNPCANGGTCKETSQGYECHCAIGWSGTSCEINVDDCTPNQCKH 382
Query: 479 ---------------------ESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWML 595
++C + +++PCV+A + C ++ CE P W
Sbjct: 383 GGTCQDLVNGFKCACPPHWTGKTCQIDANECEDKPCVNA-KSCHNLIGAYFCECLPGWSG 441
Query: 596 YNCKKSCNHCRDARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC--- 766
NC + N C+ + ++ CKDL N C PG+ + C C
Sbjct: 442 QNCDININDCKG---QCLNGGTCKDL-------VNGYRCLCPPGYTGEQCEKDVDECASS 491
Query: 767 -----GGCRD 781
G C+D
Sbjct: 492 PCLNGGRCQD 501
Score = 46.2 bits (108), Expect = 1e-04
Identities = 49/217 (22%), Positives = 76/217 (35%)
Frame = +2
Query: 5 PNCIDRDRNCQMWSDRGECGINPEAMLVTCKKTCNQCGNPGKCSDYNRNCTKWAREGLCE 184
PN CQ + +C P TC+ N+C + K ++C CE
Sbjct: 377 PNQCKHGGTCQDLVNGFKCACPPHWTGKTCQIDANECED--KPCVNAKSCHNLIGAYFCE 434
Query: 185 KNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKA 364
+ +NC + + C+ CLN +C + C PGY C+K
Sbjct: 435 CLPGWSGQNCDININDCKG---------QCLNGG-TCKDLVNGYRCLCPPGYTGEQCEKD 484
Query: 365 CNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNRPCVDANQDC 544
+ C + C + RC C F Q C+ C K PC + Q C
Sbjct: 485 VDECAS-SPCLN-GGRCQDEVNGFQCLCPAGFSGQLCQLDIDYC----KPNPCQNGAQ-C 537
Query: 545 AGWAASHECETNPSWMLYNCKKSCNHCRDARLESISN 655
A+ + C+ + NC +HCR + I +
Sbjct: 538 FNLASDYFCKCPDDYEGKNCSHLKDHCRTTSCQVIDS 574
Score = 42.7 bits (99), Expect = 0.001
Identities = 44/208 (21%), Positives = 72/208 (34%)
Frame = +2
Query: 11 CIDRDRNCQMWSDRGECGINPEAMLVTCKKTCNQCGNPGKCSDYNRNCTKWAREGLCEKN 190
CID+ Q G G++ E + C + N C N G C D + CE
Sbjct: 641 CIDKVNVYQCICADGWEGVHCEINIDDC--SLNPCLNKGACQDL-------VNDFYCECR 691
Query: 191 FNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKACN 370
+ K C C + N+ +C D +C +PG+ +C A N
Sbjct: 692 NGWKGKTCHSRDSQCDEA---------TCNNGGTCHDEGDTFKCRCSPGWEGATCNIAKN 742
Query: 371 VCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNRPCVDANQDCAG 550
N C + C + C + C E+ C+ PC ++ C
Sbjct: 743 SSCLPNPC-ENGGTCVVNGDSFNCVCKEGWEGSTCTENTNDCN----PHPCYNSG-TCVD 796
Query: 551 WAASHECETNPSWMLYNCKKSCNHCRDA 634
+ CE P + +C+ + N C+ +
Sbjct: 797 GENWYRCECAPGFAGPDCRININECQSS 824
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,668,043
Number of Sequences: 369166
Number of extensions: 2382757
Number of successful extensions: 8324
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6634
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7802
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7357347200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)