Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_022_K13 (514 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q7TMR0|PCP_MOUSE Lysosomal Pro-X carboxypeptidase precur... 113 3e-25 sp|P34676|YO26_CAEEL Putative serine protease Z688.6 precursor 112 7e-25 sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase precur... 111 9e-25 sp|Q5RBU7|PCP_PONPY Lysosomal Pro-X carboxypeptidase precur... 110 2e-24 sp|Q9EPB1|DPP2_RAT Dipeptidyl-peptidase II precursor (DPP I... 99 4e-21 sp|Q9ET22|DPP2_MOUSE Dipeptidyl-peptidase II precursor (DPP... 96 6e-20 sp|Q9UHL4|DPP2_HUMAN Dipeptidyl-peptidase II precursor (DPP... 94 2e-19 sp|P34610|PCP1_CAEEL Putative serine protease pcp-1 precursor 90 3e-18 sp|Q9NQE7|TSSP_HUMAN Thymus-specific serine protease precursor 44 2e-04 sp|Q9QXE5|TSSP_MOUSE Thymus-specific serine protease precursor 40 0.003
>sp|Q7TMR0|PCP_MOUSE Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase) (PRCP) (Proline carboxypeptidase) Length = 491 Score = 113 bits (282), Expect = 3e-25 Identities = 55/130 (42%), Positives = 79/130 (60%), Gaps = 1/130 (0%) Frame = +1 Query: 124 QYETKYFPTYLDHFTYKNDSNKFLMKYLISTKNFVE-GNPILFYCGNEGSIELFANNSGF 300 +Y YF +DHF + D F +YL++ K++ G ILFY GNEG I F NN+GF Sbjct: 45 KYSVLYFEQKVDHFGFA-DMRTFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGF 103 Query: 301 VWELGEQLSAIVVFAEHRFYGSTLPFGKKSYDSAQYFGYLNSEQXXXXXXXXXXXXKYNL 480 +W++ E+L A++VFAEHR+YG +LPFG+ S+ +Q+ +L SEQ + + Sbjct: 104 MWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTI 163 Query: 481 PGASHSPVIA 510 PGA PVIA Sbjct: 164 PGAQGQPVIA 173
>sp|P34676|YO26_CAEEL Putative serine protease Z688.6 precursor Length = 507 Score = 112 bits (279), Expect = 7e-25 Identities = 56/133 (42%), Positives = 80/133 (60%), Gaps = 1/133 (0%) Frame = +1 Query: 118 EFQYETKYFPTYLDHFTYKNDSNKFLMKYLISTKNFVEGNPILFYCGNEGSIELFANNSG 297 +++YE Y +D F + ND +F ++Y ++ ++ G PILFY GNEGS+E FA N+G Sbjct: 38 KYKYEEGYLKAPIDPFAFTNDL-EFDLRYFLNIDHYETGGPILFYTGNEGSLEAFAENTG 96 Query: 298 FVWELGEQLSAIVVFAEHRFYGSTLPFGKKSYDSAQYFGYLNSEQXXXXXXXXXXXXK-Y 474 F+W+L +L A VVF EHRFYG + PF +SY ++ GYL+S+Q K Sbjct: 97 FMWDLAPELKAAVVFVEHRFYGKSQPFKNESYTDIRHLGYLSSQQALADFALSVQFFKNE 156 Query: 475 NLPGASHSPVIAF 513 + GA S VIAF Sbjct: 157 KIKGAQKSAVIAF 169
>sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase) (PRCP) (Proline carboxypeptidase) (Angiotensinase C) (Lysosomal carboxypeptidase C) Length = 496 Score = 111 bits (278), Expect = 9e-25 Identities = 55/129 (42%), Positives = 78/129 (60%), Gaps = 1/129 (0%) Frame = +1 Query: 127 YETKYFPTYLDHFTYKNDSNKFLMKYLISTKNFVE-GNPILFYCGNEGSIELFANNSGFV 303 Y YF +DHF + N F +YL++ K + + G ILFY GNEG I F NN+GF+ Sbjct: 48 YSVLYFQQKVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFM 106 Query: 304 WELGEQLSAIVVFAEHRFYGSTLPFGKKSYDSAQYFGYLNSEQXXXXXXXXXXXXKYNLP 483 W++ E+L A++VFAEHR+YG +LPFG S+ +++ +L SEQ K +P Sbjct: 107 WDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIP 166 Query: 484 GASHSPVIA 510 GA + PVIA Sbjct: 167 GAENQPVIA 175
>sp|Q5RBU7|PCP_PONPY Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase) (PRCP) (Proline carboxypeptidase) Length = 496 Score = 110 bits (275), Expect = 2e-24 Identities = 54/129 (41%), Positives = 78/129 (60%), Gaps = 1/129 (0%) Frame = +1 Query: 127 YETKYFPTYLDHFTYKNDSNKFLMKYLISTKNFVE-GNPILFYCGNEGSIELFANNSGFV 303 Y YF +DHF + N F +YL++ K + + G ILFY GNEG I F NN+GF+ Sbjct: 48 YSVLYFQQKVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFM 106 Query: 304 WELGEQLSAIVVFAEHRFYGSTLPFGKKSYDSAQYFGYLNSEQXXXXXXXXXXXXKYNLP 483 W++ E+L A++VFAEHR+YG +LPFG ++ +++ +L SEQ K +P Sbjct: 107 WDVAEELKAMLVFAEHRYYGESLPFGDNTFKDSRHLNFLTSEQALADFAELIKHLKRTIP 166 Query: 484 GASHSPVIA 510 GA + PVIA Sbjct: 167 GAENQPVIA 175
>sp|Q9EPB1|DPP2_RAT Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl aminopeptidase II) (Quiescent cell proline dipeptidase) (Dipeptidyl peptidase 7) Length = 500 Score = 99.4 bits (246), Expect = 4e-21 Identities = 59/137 (43%), Positives = 78/137 (56%), Gaps = 2/137 (1%) Frame = +1 Query: 109 SNLEFQYETKYFPTYLDHFTYKNDSNK-FLMKYLISTKNFVEGN-PILFYCGNEGSIELF 282 S L+ + YF Y+DHF +++ SNK F ++L+S K + G PI FY GNEG I Sbjct: 35 SVLDPDFRENYFEQYMDHFNFESFSNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSL 94 Query: 283 ANNSGFVWELGEQLSAIVVFAEHRFYGSTLPFGKKSYDSAQYFGYLNSEQXXXXXXXXXX 462 ANNSGF+ EL Q A++VFAEHR+YG +LPFG +S Y L EQ Sbjct: 95 ANNSGFIVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRG-YTQLLTVEQALADFAVLLQ 153 Query: 463 XXKYNLPGASHSPVIAF 513 ++NL G +P IAF Sbjct: 154 ALRHNL-GVQDAPTIAF 169
>sp|Q9ET22|DPP2_MOUSE Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl aminopeptidase II) (Quiescent cell proline dipeptidase) (Dipeptidyl peptidase 7) Length = 506 Score = 95.5 bits (236), Expect = 6e-20 Identities = 57/135 (42%), Positives = 76/135 (56%), Gaps = 2/135 (1%) Frame = +1 Query: 115 LEFQYETKYFPTYLDHFTYKNDSNK-FLMKYLISTKNFVEGN-PILFYCGNEGSIELFAN 288 L+ + YF Y+DHF +++ NK F ++L+S K + G PI FY GNEG I FAN Sbjct: 37 LDPDFHENYFEQYMDHFNFESFGNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSFAN 96 Query: 289 NSGFVWELGEQLSAIVVFAEHRFYGSTLPFGKKSYDSAQYFGYLNSEQXXXXXXXXXXXX 468 NSGF+ EL Q A++VFAEHR+YG +LPFG +S Y L EQ Sbjct: 97 NSGFMVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRG-YTQLLTVEQALADFAVLLQAL 155 Query: 469 KYNLPGASHSPVIAF 513 + +L G +P IAF Sbjct: 156 RQDL-GVHDAPTIAF 169
>sp|Q9UHL4|DPP2_HUMAN Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl aminopeptidase II) (Quiescent cell proline dipeptidase) (Dipeptidyl peptidase 7) Length = 492 Score = 94.0 bits (232), Expect = 2e-19 Identities = 54/131 (41%), Positives = 76/131 (58%), Gaps = 2/131 (1%) Frame = +1 Query: 127 YETKYFPTYLDHFTYKNDSNK-FLMKYLISTKNFVEGN-PILFYCGNEGSIELFANNSGF 300 ++ ++F LDHF ++ NK F ++L+S + +V G PI FY GNEG + FANNSGF Sbjct: 31 FQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSGF 90 Query: 301 VWELGEQLSAIVVFAEHRFYGSTLPFGKKSYDSAQYFGYLNSEQXXXXXXXXXXXXKYNL 480 V EL + A++VFAEHR+YG +LPFG +S + L EQ + +L Sbjct: 91 VAELAAERGALLVFAEHRYYGKSLPFGAQSTQRG-HTELLTVEQALADFAELLRALRRDL 149 Query: 481 PGASHSPVIAF 513 GA +P IAF Sbjct: 150 -GAQDAPAIAF 159
>sp|P34610|PCP1_CAEEL Putative serine protease pcp-1 precursor Length = 565 Score = 90.1 bits (222), Expect = 3e-18 Identities = 43/93 (46%), Positives = 58/93 (62%) Frame = +1 Query: 154 LDHFTYKNDSNKFLMKYLISTKNFVEGNPILFYCGNEGSIELFANNSGFVWELGEQLSAI 333 LDHFT+ D+ F M+ + + + G PI FY GNEG +E F +G +++L +A Sbjct: 51 LDHFTW-GDTRTFDMRVMWNNTFYKPGGPIFFYTGNEGGLESFVTATGMMFDLAPMFNAS 109 Query: 334 VVFAEHRFYGSTLPFGKKSYDSAQYFGYLNSEQ 432 ++FAEHRFYG T PFG +SY S GYL SEQ Sbjct: 110 IIFAEHRFYGQTQPFGNQSYASLANVGYLTSEQ 142
>sp|Q9NQE7|TSSP_HUMAN Thymus-specific serine protease precursor Length = 514 Score = 44.3 bits (103), Expect = 2e-04 Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Frame = +1 Query: 154 LDHFTYKNDSNKFLMKYLISTKNFV-EGNPILFYCGNEGSIELFANNSGFVWELGEQLSA 330 LD F +D FL +Y ++ +++V + PI + G EGS+ + G L A Sbjct: 66 LDPFNV-SDRRSFLQRYWVNDQHWVGQDGPIFLHLGGEGSLGPGSVMRGHPAALAPAWGA 124 Query: 331 IVVFAEHRFYGSTLPFG 381 +V+ EHRFYG ++P G Sbjct: 125 LVISLEHRFYGLSIPAG 141
>sp|Q9QXE5|TSSP_MOUSE Thymus-specific serine protease precursor Length = 509 Score = 40.0 bits (92), Expect = 0.003 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Frame = +1 Query: 154 LDHFTYKNDSNKFLMKYLISTKNFV-EGNPILFYCGNEGSIELFANNSGFVWELGEQLSA 330 LD F +D FL +Y ++ ++ + P+ + G EGS+ + +G L A Sbjct: 65 LDPFN-ASDRRTFLQRYWVNDQHRTGQDVPVFLHIGGEGSLGPGSVMAGHPAALAPAWGA 123 Query: 331 IVVFAEHRFYGSTLPFG 381 +V+ EHRFYG ++P G Sbjct: 124 LVISLEHRFYGLSMPAG 140
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 54,944,250 Number of Sequences: 369166 Number of extensions: 1059177 Number of successful extensions: 2587 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2525 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2582 length of database: 68,354,980 effective HSP length: 103 effective length of database: 49,327,275 effective search space used: 3304927425 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)